Phosphorus, Sulfur, and Silicon and the Related Elements最新文献_第7页

Spectral study of phosphonium salts synthesized from Michael acceptors Michael受体合成磷盐的光谱研究

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2022.2150854

Elleuch Haitham , Ferid Yaccoubi

引用次数: 0

Stable cysteine sulfenic acid: synthesis by direct oxidation of a thiol, crystallographic analysis, and elucidation of reactivities 稳定半胱氨酸磺酸:由硫醇直接氧化合成，结晶学分析和反应性说明

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2195650

Kei Goto , Tsukasa Sano , Ryosuke Masuda , Shotaro Otaka , Ryutaro Kimura , Shohei Sase , Satoru Kuwano

{"title":"Stable cysteine sulfenic acid: synthesis by direct oxidation of a thiol, crystallographic analysis, and elucidation of reactivities","authors":"Kei Goto , Tsukasa Sano , Ryosuke Masuda , Shotaro Otaka , Ryutaro Kimura , Shohei Sase , Satoru Kuwano","doi":"10.1080/10426507.2023.2195650","DOIUrl":"https://doi.org/10.1080/10426507.2023.2195650","url":null,"abstract":"<div>A small-molecule cysteine sulfenic acid (Cys–SOH) was synthesized and isolated as stable crystals, for the first time, by utilizing a nanosized molecular cavity as a protective cradle. The cradled Cys–SOH was synthesized by direct oxidation of the corresponding cysteine thiol with H2O2 under basic conditions and its structure was established by X-ray crystallographic analysis. In the reaction of the cradled Cys–SOH with a thiol to produce the disulfide, a remarkable acceleration was observed upon the addition of an amine base. This suggests the important role of base in the reaction of Cys–SOH with thiols in biological systems. The cradled Cys–SOH was reduced to the cysteine thiol by dithiothreitol or triphenylphosphine. The high stability and sufficient reactivity of the cradled Cys–SOH indicate its usefulness as a small-molecule model compound for better understanding the chemical behavior of Cys–SOH in biological systems.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49863684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catalyst-free thia-Diels-Alder click reaction for the labeling of peptides for imaging applications 无催化剂的thia-Diels-Alder点击反应用于成像应用的肽标记

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2165659

Timothé Maujean , Patrice Marchand , Patrick Wagner , Stéphanie Riché , Frédéric Boisson , Nicolas Girard , Julie Karpenko , Dominique Bonnet , Mihaela Gulea

引用次数: 0

Design, synthesis and molecular docking studies of 5-fluoro 1-aryl/alkyl sulfonyl benzimidazole derivatives for treatment of Parkinson’s disease 治疗帕金森病的5-氟1-芳基/烷基磺酰基苯并咪唑衍生物的设计、合成及分子对接研究

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2022.2150852

Subarna Roy , Subhadeep Sen , Samiran Saha , Sandip Kumar Deb , Bhagat Singh , Goutam Biswas

{"title":"Design, synthesis and molecular docking studies of 5-fluoro 1-aryl/alkyl sulfonyl benzimidazole derivatives for treatment of Parkinson’s disease","authors":"Subarna Roy , Subhadeep Sen , Samiran Saha , Sandip Kumar Deb , Bhagat Singh , Goutam Biswas","doi":"10.1080/10426507.2022.2150852","DOIUrl":"https://doi.org/10.1080/10426507.2022.2150852","url":null,"abstract":"<div>Novel sulfonyl derivatives of 5-fluoro-substituted benzimidazole were synthesized and characterized by 1H-NMR, 13C-NMR, 19F-NMR and mass spectrometry. Molecular docking study against monoamine oxidase B (MAO-B), responsible for Parkinson’s disease (PD), was performed. The binding energy and interactions with active amino acid residues in the binding site of newly synthesized derivatives, as well as conventional inhibitors (Selegiline and Rasagiline), were investigated and presented. According to the docking scores predicted by ADV (AutoDock vina) and AD (AutoDock), most of the synthesized derivatives have higher binding affinity toward MAO-B than the conventional inhibitors. This study shows that these fluoro-substituted benzimidazole derivatives can be developed into essential drugs for the treatment of PD. The antibacterial property of these compounds was investigated by disk diffusion test and minimum inhibitory concentration (MIC), against gram-negative and gram-positive bacteria. And the results were further verified by the bacteria kill test with respect to time. All the synthesized compounds demonstrated considerable antibacterial activity against both bacterial strains. Therefore, this work focuses on defining the efficiency of different types of sulfonyl derivatives of fluorinated benzimidazole in biomedical research for the treatment of PD highlighting their versatile biological properties.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49700418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discovery of novel carbazole derivatives containing a 1,3,4-thiadiazole moiety as antifungal candidates 发现含有1,3,4-噻二唑片段的新型咔唑衍生物作为抗真菌候选物

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2191961

Chenghao Tang , Xingju Chen , Shengzhou Yang , Wenbo Guo , Xiumei Yang , Pei Li , Xiang Wang

{"title":"Discovery of novel carbazole derivatives containing a 1,3,4-thiadiazole moiety as antifungal candidates","authors":"Chenghao Tang , Xingju Chen , Shengzhou Yang , Wenbo Guo , Xiumei Yang , Pei Li , Xiang Wang","doi":"10.1080/10426507.2023.2191961","DOIUrl":"https://doi.org/10.1080/10426507.2023.2191961","url":null,"abstract":"<div>Fifteen novel carbazole derivatives of 2-(9H-carbazol-9-yl)-N-(5-phenyl-1,3,4-thiadiazol-2-yl)acetamide were designed, synthesized and evaluated for their antifungal activities against Pellicularia sasakii (P. sasakii), Fusarium oxysporum (F. oxysporum), Gibberella zeae (G. zeae), Phytophthora infestans (P. infestans), Cytospora mandshurica (C. mandshurica) and Capsicum wilt (C. wilt). The results of antifungal activity tests indicated that the inhibitory rates of compounds 2-(2-chloro-9H-carbazol-9-yl)-N-(5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl)acetamide (3h) and 2-(2-chloro-9H-carbazol-9-yl)-N-(5-(thiophen-2-yl)-1,3,4-thiadiazol-2-yl)acetamide (3o) against P. sasakii were 72.89% and 74.29%, respectively, which displayed better bioactivity compared with commercial fungicides hymexazol (53.09%) and carbendazim (69.65%). Meanwhile, compounds 2-(9H-carbazol-9-yl)-N-(5-(thiophen-2-yl)-1,3,4-thiadiazol-2-yl)acetamide (3f) and 2-(3-iodo-9H-carbazol-9-yl)-N-(5-(p-tolyl)-1,3,4-thiadiazol-2-yl)acetamide (3 l) exhibited the inhibition rates of 72.40% and 67.65% against C. wilt, respectively, which were better than the commercial fungicides hymexazol (50.21%) and carbendazim (65.33%).</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49712579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Targeted application of GO to improve mechanical and thermal properties of PVCS/RS composites 有针对性地应用氧化石墨烯改善PVCS/RS复合材料的力学和热性能

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2022.2150853

Milad Sheydaei , Vahid Pouraman , Milad Edraki , Ebrahim Alinia-Ahandani , Seyedeh Mozhdeh Asadi-Sadeh

{"title":"Targeted application of GO to improve mechanical and thermal properties of PVCS/RS composites","authors":"Milad Sheydaei , Vahid Pouraman , Milad Edraki , Ebrahim Alinia-Ahandani , Seyedeh Mozhdeh Asadi-Sadeh","doi":"10.1080/10426507.2022.2150853","DOIUrl":"https://doi.org/10.1080/10426507.2022.2150853","url":null,"abstract":"<div>In this study, wood–plastic composites (WPCs) were prepared from polyvinyl chloride (PVC) modified by sodium trisulfide (Na2S3) and rice straw (RS) treated with 7% sodium hydroxide solution. The results showed that after modification, 35.4 wt. % of sulfur is present in the structure of PVC containing sulfur (PVCS). The structural, morphological, thermal, and mechanical properties of the samples were investigated. As the RS fibers content in the composites increased, the thermal stability also increased but the mechanical properties decreased slightly. Moreover, the presence of sulfur in the matrix created antifungal properties that the results showed us that the PVCS can inhibit and kill Aspergillus niger and Aspergillus brasiliensis. Also, graphene oxide (GO) was added to the matrix to improve its properties. The addition of GO to composite improved the mechanical and thermal properties to extent that its mechanical properties were better than the sample without RS.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49728230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Attempts to oxidize sulfides under mechanochemical conditions: synthetic and stereochemical aspects 尝试在机械化学条件下氧化硫化物:合成和立体化学方面

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2193405

Aneta Wróblewska , Kamil Bugaj , Jakub Łagiewka , Tomasz Girek , Jozsef Rabai , Józef Drabowicz

引用次数: 0

A Box-Behnken design-based chemometric approach to optimize the removal of phosphate ions from water using Punica granatum shells 基于Box-Behnken设计的化学计量学方法优化石榴壳对水中磷酸盐离子的去除效果

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2174542

H. Bendjeffal , H. Mamine , T. Metidji , A. Djebli , R. Diaf , Y. Bouhedja

{"title":"A Box-Behnken design-based chemometric approach to optimize the removal of phosphate ions from water using Punica granatum shells","authors":"H. Bendjeffal , H. Mamine , T. Metidji , A. Djebli , R. Diaf , Y. Bouhedja","doi":"10.1080/10426507.2023.2174542","DOIUrl":"https://doi.org/10.1080/10426507.2023.2174542","url":null,"abstract":"<div>The present study was aimed at evaluating the adsorption of phosphate ions using Punica granatum shells (PGS) as an environmentally friendly and economical sorbent material. The PGS powder was characterized by several techniques including BET, <math><msub><mrow><mi>p</mi><mi>H</mi></mrow><mrow><mi>pzc</mi></mrow></msub><mo>,</mo></math> SEM, and FTIR, as well as its adsorption capacity evaluated with the sorption of <math><msubsup><mrow><mi>P</mi><mi>O</mi></mrow><mrow><mn>4</mn></mrow><mrow><mn>3</mn><mo>−</mo></mrow></msubsup></math> from water. To achieve adequate removal of <math><msubsup><mrow><mi>P</mi><mi>O</mi></mrow><mrow><mn>4</mn></mrow><mrow><mn>3</mn><mo>−</mo></mrow></msubsup></math> from water, a chemometric method based on the Box–Behnken design was applied to optimize the influence of the main operating factors such as the PGS amount (0.10–1 g L−1), medium pH (3–9), and <math><msubsup><mrow><mi>P</mi><mi>O</mi></mrow><mrow><mn>4</mn></mrow><mrow><mn>3</mn><mo>−</mo></mrow></msubsup></math> initial concentration (10–100 mg L−1) on the adsorption processes. Noteworthy, the best adsorption amount (29.31 mg g−1) was obtained at a pollutant dose of 72.72 mg L−1, an adsorbent quantity of 1 g L−1 in medium acid pH 3 at 25 °C. The modeling study suggests that the process of <math><msubsup><mrow><mi>P</mi><mi>O</mi></mrow><mrow><mn>4</mn></mrow><mrow><mn>3</mn><mo>−</mo></mrow></msubsup></math> uptake follows the pseudo-second-order model with a maximum adsorbent quantity of 32.25 mg g−1.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49706627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Microwave assisted, Cu-catalyzed synthesis of sulfonamides using sodium sulfinates and amines 微波辅助铜催化亚硫酸钠和胺合成磺胺类药物

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2198714

Anil Nikam , Jagannath Jadhav , Sagar Sankpal

引用次数: 0

One-pot synthesis of a new class of alkynyl anionic synthons: the 4-(2',2-trimethylsilylethynylphenoxymethyl)-2H-chromen-2-ones 一类新的炔基阴离子合成物:4-(2′，2-三甲基硅乙基苯氧甲基)- 2h -2-酮

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2022.2150851

G.B. Venkatesh , S. HariPrasad , A.S. Jeevan Chakravarthy

引用次数: 0