Phosphorus, Sulfur, and Silicon and the Related Elements最新文献_第10页

Synthesis of nitroarenes and azoxyarenes through the selenium-mediated on water oxidation of aryl amines 硒介导芳基胺水氧化合成硝基芳烃和偶氮氧芳烃

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2166044

Antonella Capperucci , Camilla Dalia , Alessio Cenni , Damiano Tanini

引用次数: 1

Optimization synthesis of phosphorous-containing natural products fosmidomycin and FR900098 含磷天然产物fosmidomycin和FR900098的优化合成

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2173756

Xin Wu , Hongrui Ping , Chunlin Song , Jiang Duan , Aidong Zhang

引用次数: 1

An overview on synthetic routes of anti-inflammatory active scaffolds including thiazole and thiazolidine cores 噻唑类和噻唑烷类抗炎活性支架的合成途径综述

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2189253

Ayushi Bhatnagar , Gangotri Pemawat

{"title":"An overview on synthetic routes of anti-inflammatory active scaffolds including thiazole and thiazolidine cores","authors":"Ayushi Bhatnagar , Gangotri Pemawat","doi":"10.1080/10426507.2023.2189253","DOIUrl":"https://doi.org/10.1080/10426507.2023.2189253","url":null,"abstract":"<div>Thiazoles and thiazolidines are widespread occurring in natural products. They act as a viaduct between medicinal and organic chemistry. The presence of sulfur elevates their pharmacological activities whereas the presence of nitrogen makes it an active moiety for the development of scaffolds in a drug discovery process. Therefore, both of these compounds can be utilized as a vehicle for the synthesis of beneficial organic amalgamation. Thiazole exhibits high curative properties which enabled researchers to focus on composing various attempts to integrate and investigate novel structural precursors, which are more effective. On the other hand, thiazolidine and its derivatives are used in scrutinizing drug designs for the development of multifunctional drugs and modifying their activity. Both the nucleus and their derivative are blended in the evolution of drugs that display selective inhibition of both types of cyclooxygenases as well as lipoxygenase enzymes. In the present review, different recent synthetic routes of this important class are presented which show anti-inflammatory activities and enhanced potential in the inhibition of COX enzymes.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49700531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of seed crystal concentration, pH, and stirring rate on ammonium sulfate crystallization under the action of ammonium nitrate 种子结晶浓度、pH、搅拌速率对硝酸铵作用下硫酸铵结晶的影响

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2175828

Gaoyong Zi , Bangfu Huang , Meng Dai , Zhe Shi , Zhenjing Wen , Wanjun Li , Liubin Luo , Linjing Yang

引用次数: 0

Synthesis and fungicidal activity of 2-(methylthio)-4-methylpyrimidine carboxamides bearing a carbamate moiety 含氨基甲酸酯部分的2-(甲基硫代)-4-甲基嘧啶类羧酰胺的合成及其杀真菌活性

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2192934

Fu-Hao Zhang , Huan Zhang , Chang-Xing Sun , Peng-Hui Li , Lin Jiang

{"title":"Synthesis and fungicidal activity of 2-(methylthio)-4-methylpyrimidine carboxamides bearing a carbamate moiety","authors":"Fu-Hao Zhang , Huan Zhang , Chang-Xing Sun , Peng-Hui Li , Lin Jiang","doi":"10.1080/10426507.2023.2192934","DOIUrl":"https://doi.org/10.1080/10426507.2023.2192934","url":null,"abstract":"<div>A series of 1-[2-(4-methyl-2-(methylthio)pyrimidine-5-carboxamido)phenyl]ethyl-substitutedphenyl carbamates (3a–3i) were designed and synthesized, using 4-methyl-2-(methylthio)pyrimidine-5-carboxylic acid, (2-aminophenyl)ethan-1-one, and substituted phenyl isocyanates as starting materials. Their structures were characterized by 1H NMR, 13C NMR, IR and HRMS. The in vitro fungicidal activities against Sclerotinia sclerotiorum were evaluated, and the result showed that some compounds displayed moderate antifungal activity with >60% inhibitory rates, among which 1-[2-(4-methyl-2-(methylthio)pyrimidine-5-carboxamido)phenyl] ethyl-(2- methyl phenyl)carbamate (3a) and 1-[2-(4-methyl-2-(methylthio)pyrimidine-5- carboxamido)phenyl] ethyl-(3-trifluoromethyl phenyl)carbamate (3g) held inhibitory rates of 69.5% and 70.3% at 100 mg/L, respectively. Molecular docking study showed that 3g can form two hydrogen bonds and a cation-π interaction with succinate dehydrogenase.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49706815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Aromatic iodonium/sulfonium rearrangement using difluoroenol silyl ethers 使用二氟烯醇硅基醚的芳香碘/磺胺重排

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2022.2113977

Peng Du , Lijiang Zhou , Zongwei Zhang , Xin Huang , Bo Peng

引用次数: 0

3,3-Disubstituted 1-acylthioureas as ionophores for Pb(II)-ion selective electrodes: physical and chemical characterization of the sensing membranes 3,3-二取代1-酰基硫脲作为铅离子选择电极的离子载体:传感膜的物理和化学表征

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2022.2152814

Ana Rosa Lazo-Fraga , Mayra Paulina Hernández , Alicia María Díaz-García , Marcia Viltres-Portales , Osvaldo Estévez-Hernández

{"title":"3,3-Disubstituted 1-acylthioureas as ionophores for Pb(II)-ion selective electrodes: physical and chemical characterization of the sensing membranes","authors":"Ana Rosa Lazo-Fraga , Mayra Paulina Hernández , Alicia María Díaz-García , Marcia Viltres-Portales , Osvaldo Estévez-Hernández","doi":"10.1080/10426507.2022.2152814","DOIUrl":"https://doi.org/10.1080/10426507.2022.2152814","url":null,"abstract":"<div>Solid-state Pb(II) ion selective electrodes were developed, which are based on 3,3-disubstituted 1-acylthioureas as ionophores and use PVC membranes. 1-Benzoyl, 1-(2-furoyl), 3,3-diethyl and 3,3-diphenyl were the substituent groups on the thioureide core. The analytical parameters for the constructed electrodes were studied. The electrodes based on 3,3-diethyl substituted thiourea derivatives showed better analytical response to Pb(II) ions with suitable sensitivity and an average lifetime of more than 30 days. Cu(II), Hg(II) and Ag(I) ions were interfering species during Pb(II) detection. Scanning electron microscopy and atomic force microscopy micrographs of the activated sensing membranes revealed morphological changes, which have been associated with the performance of the sensors. The studies have suggested that the detection of few large size particles or aggregates at the membrane surface are responsible for inadequate functioning of the prepared electrodes. This pattern was mainly observed for the sensing membranes based on 3,3-diphenyl groups as substituents and is related to unfavorable steric and electronic factors. Furthermore, X-ray photoelectron spectroscopy profiles S2p and Pb4f supported chemically the analytical response displayed for the four membrane systems. The X-ray photoelectron spectroscopy results combined with scanning electron microscopy and atomic force microscopy studies shed light on the working mechanism of the studied electrodes.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49902487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel thiourea derivatives against Mycobacterium tuberculosis: synthesis, characterization and molecular docking studies 新型抗结核分枝杆菌硫脲衍生物:合成、表征及分子对接研究

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2201503

Emine Kutlu , Fatih Mehmet Emen , Kübra Yıldırım , Cemilenur Ataş , Ruken Esra Demirdogen , Tuncay Yesilkaynak , Neslihan Kaya Kinaytürk , Ece Şimşek , Ahmet Yılmaz Çoban

{"title":"Novel thiourea derivatives against Mycobacterium tuberculosis: synthesis, characterization and molecular docking studies","authors":"Emine Kutlu , Fatih Mehmet Emen , Kübra Yıldırım , Cemilenur Ataş , Ruken Esra Demirdogen , Tuncay Yesilkaynak , Neslihan Kaya Kinaytürk , Ece Şimşek , Ahmet Yılmaz Çoban","doi":"10.1080/10426507.2023.2201503","DOIUrl":"https://doi.org/10.1080/10426507.2023.2201503","url":null,"abstract":"<div> N-((2-chloropyridin-3-yl)carbamothioyl)thiophene-2-carboxamide (HL1), N-((6-methylpyridin-2-yl)carbamothioyl)thiophene-2-carboxamide (HL2), N-(allylcarbamothioyl)thiophene-2-carboxamide (HL3), 2-chloro-N-(methyl(1-phenylethyl)carbamothioyl)benzamide (HL4) and 2-chloro-N-(bis((R)-1-phenylethyl)carbamothioyl)benzamide (HL5) were synthesized and characterized via FT-IR, 1H-NMR, 13C-NMR and HR-MS techniques and HL3 was characterized via a single crystal X-ray diffraction experiment. The antituberculosis activity of the synthesized thiourea derivatives was tested against the H37RV (ATCC27294), ATCC35822 (INH resistant), ATCC35838 (RIF resistant), ATCC35820 (STM resistant) and ATCC35837 (EMB resistant) standard bacteria strains. The thiourea derivatives were tested on two MDR and one primary drug-sensitive isolates with the microplate nitrate reductase test method. The results indicated that HL2 and HL3 had tuberculosis activity on some of the isolates. It was observed that HL4 was the most effective among all the thiourea derivatives. The interaction mechanism of the synthesized compounds on 2X23, a tuberculosis protein, was investigated via molecular docking method. The interaction was observed to occur over S and Cl atoms in all the compounds. The compounds containing the methyl group were observed to interact via this group.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-assisted construction of novel diethyl {(4-oxo-1,4-dihydroquinolin-3-yl) (aryl/heteroarylamino)methyl}phosphonates using CdI2 nanoparticles as an efficient catalyst: Synthesis, characterization, and antifungal properties 超声辅助构建新型二乙基{(4-氧-1,4-二氢喹啉-3-基)(芳基/杂芳胺)甲基}膦酸盐:CdI2纳米颗粒作为高效催化剂:合成、表征和抗真菌性能

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2207709

Mohamed Hussien , Tarik E. Ali , Ibrahim El-Tantawy El Sayed , Abdelaleem Hassan Abdelaleem , H. M. Torkey

{"title":"Ultrasound-assisted construction of novel diethyl {(4-oxo-1,4-dihydroquinolin-3-yl) (aryl/heteroarylamino)methyl}phosphonates using CdI2 nanoparticles as an efficient catalyst: Synthesis, characterization, and antifungal properties","authors":"Mohamed Hussien , Tarik E. Ali , Ibrahim El-Tantawy El Sayed , Abdelaleem Hassan Abdelaleem , H. M. Torkey","doi":"10.1080/10426507.2023.2207709","DOIUrl":"https://doi.org/10.1080/10426507.2023.2207709","url":null,"abstract":"<div>The synthesis of some novel diethyl {(4-oxo-1,4-dihydroquinolin-3-yl)(aryl/heteroaryl-amino)methyl}phosphonates, was achieved. The methodology is based on one-pot three-component reaction of 4-oxo-1,4-dihydroquinoline-3-carboxaldehyde (1), amine, and diethyl phosphite in the presence of CdI2 nanoparticles as an efficient catalyst under conventional heating at 80 °C or ultrasound irradiation at 50 °C. The mild reaction conditions, operational simplicity, and excellent yields are the essential advantages of this protocol. Most of the products recorded inhibitory effects toward plant pathogenic fungi nearly to the standard control. The hybridization between diethyl α-aminophosphonate and quinolin-4-one moieties clubbed with sulfonamide, antipyrine, or 1,2,4-triazine in one molecular frame displayed good antifungal activities.</div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A greener approach of synthesis of new 2-chloro-1,3,2-diazaphosphinin-4-one-2-oxide derivatives 新的2-氯-1,3,2-二氮磷-4- 1 -2-氧化物衍生物的绿色合成方法

IF 1.3 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2023-01-01 DOI: 10.1080/10426507.2023.2184362

Samar Kherfani , Raoudha Abderrahim

引用次数: 0