利用生物可再生的2-甲基四氢呋喃溶剂合成2-乙烯基吡啶

IF 1.4 4区化学 Q4 CHEMISTRY, INORGANIC & NUCLEAR

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2024-09-02 DOI:10.1080/10426507.2024.2420011

Manchikanti M. Chandrasekhar , D. S. Ramakrishna , Priyanka Behera , Bhujanga Rao Chitturi

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引用次数: 0

摘要

本文报道了复合图法合成2-乙烯基吡啶在制药科学、材料科学和工业上的广泛应用。本方法强调使用商业上可获得的廉价原料和生物可再生溶剂。采用无毒的三聚氰胺作为绿色氯化试剂，反应过程中得到的相应副产物是可生物降解的。整个三步操作过程不需要任何色谱技术，使用>；98%的纯度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Multigram synthesis of 2-vinylpyridine using bio-renewable 2-methyl tetrahydrofuran solvent

The present work reports the synthesis of 2-vinylpyridine in multigram synthetic approach as it has tremendous application in pharmaceutical science as well as in material science and industries. This present method emphasizes the usage of commercially available inexpensive raw materials and bio renewable solvents. Nontoxic TCCA was used as green chlorinating reagent and its corresponding bi-product obtained in the course of the reaction is biodegradable in nature. This entire three step procedure does not require any chromatographic techniques and the product is obtained in 95% yield with > 98% purity.

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来源期刊

Phosphorus, Sulfur, and Silicon and the Related Elements 化学-无机化学与核化学

CiteScore

2.60

自引率

7.70%

发文量

103

审稿时长

2.1 months

期刊介绍： Phosphorus, Sulfur, and Silicon and the Related Elements is a monthly publication intended to disseminate current trends and novel methods to those working in the broad and interdisciplinary field of heteroatom chemistry.