Patient preference and adherence最新文献

{"title":"Phytomedicines in Pharmacotherapy of LUTS/BPH - What Do Patients Think?","authors":"Alexander Tamalunas, Richard Paktiaval, Philipp Lenau, Leo Federico Stadelmeier, Alexander Buchner, Thomas Kolben, Giuseppe Magistro, Christian G Stief, Martin Hennenberg","doi":"10.2147/PPA.S484632","DOIUrl":"10.2147/PPA.S484632","url":null,"abstract":"<p><strong>Purpose: </strong>Lower urinary tract symptoms (LUTS) consist of voiding and storage symptoms. While the therapeutic efficacy of current LUTS medications is limited, and with more than 20% of patients suffering from mixed symptoms, current guidelines offer nothing more than combining monotherapies. An individualized approach is urgently warranted, and phytomedicines have become an integral part of patient-empowerment in therapeutic shared-decision making processes. Therefore, we aimed to investigate patients' preference of phytomedicines and treatment adherence at the dawn of an era leaving α₁-blocker monotherapies behind.</p><p><strong>Patients and methods: </strong>A questionnaire was prepared, and patients at our tertiary referral center were given the opportunity to voluntarily participate in our survey. We collected questionnaires from 300 patients during their visits from January 2022 to December 2022.</p><p><strong>Results: </strong>With 73% (218/300), most of our study cohort had either taken one or more or were currently on prescription medication for LUTS/BPH. Patients were prescribed α₁-blockers (72%), followed by 5α-reductase inhibitors (21%), and phosphodiesterase-5-inhibitor (5%), while antimuscarinics and β₃-agonists were rarely prescribed. However, 41% (89/218) of our patients, who were taking medication for LUTS, had taken or were currently taking phytomedicines, making this the second most common drug class in our patient cohort. Patients scored the efficacy of phytomedicines at a mean in the lower third, but 87% of patients attributed excellent tolerability, and only 9% experienced side effects. While 43% of patients recommended phytomedicines for other patients, two-thirds of patients thought phytomedicines should be covered by statutory health insurance.</p><p><strong>Conclusion: </strong>We found that phytomedicines were the second most common drug class taken by LUTS patients at our hospital. Reasons may be easy availability as over the counter medication and a superior safety profile with less bothersome side effects than commonly prescribed drug classes. Taken together, phytomedicines may be able to bridge an important gap in LUTS pharmacotherapy to provide sufficient treatment adherence where prescription drug classes fail, and ultimately, adequate improvement of symptoms. However, patients need to be counseled on potentially limited efficacy.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2507-2518"},"PeriodicalIF":2.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Strategies for Enhancing Medication Adherence in the Kingdom of Saudi Arabia (KSA): A Cross-Sectional Study.","authors":"Farah Kais Alhomoud, Lama Wesam Alwohaibi, Kawthar Aljarrash, Faten Alhomoud, Khalid Alamer, Mohammed M Alsultan, Yousef Alqarni, Noor Alotaibi, Anwar Khalifah Alsaad, Afrah Dhafer Alqahtani, Reem Saad Alkhnbashi","doi":"10.2147/PPA.S499795","DOIUrl":"10.2147/PPA.S499795","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess medication adherence strategies among users in Saudi Arabia, explore the prevalence and effectiveness of behavioral, technical, and organizational tools, and identify key predictors of adherence related to demographic, health, and medication characteristics.</p><p><strong>Patients and methods: </strong>A descriptive cross-sectional study was conducted among 250 Saudi residents aged ≥18 who regularly take prescription/non-prescription medications. The questionnaire was developed through a literature review, validated by academic pharmacists, and refined based on pilot testing feedback. A convenience sampling method, complemented by snowball sampling, was employed to recruit participants. Limitations like sampling bias and self-reported data emphasize the need for broader studies. Quantitative analysis was performed using IBM SPSS.</p><p><strong>Results: </strong>Participants were predominantly young adults (84%) and females (84%), with 54% reporting being healthy and 46% managing chronic conditions. Behavioral strategies, such as time-based reminders, were the most commonly used (40%), followed by technical tools (33%), including mobile applications. Employment status significantly influenced adherence, with employed individuals (adjusted OR: 3.274, p = 0.028) and those working >8 hours daily (adjusted OR: 9.838, p = 0.049) exhibiting higher adherence. Fieldwork negatively impacted adherence (adjusted OR: 0.052, p = 0.007). While other demographic and health factors showed no significant associations, trends suggested that complex medication regimens increased the likelihood of using adherence strategies.</p><p><strong>Conclusion: </strong>Behavioral strategies, such as time- and location-based reminders, and technical tools, like apps, effectively improved medication adherence. Healthcare providers should promote simple, cost-effective methods, such as pillboxes and mobile reminders, tailored to patient needs. Addressing adherence barriers for individuals with demanding/unexpected schedules or complex regimens through targeted interventions and awareness campaigns is essential. Future research should explore these strategies' scalability and long-term impact in diverse healthcare settings.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2469-2480"},"PeriodicalIF":2.0,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstacles to Medication Adherence for Patients with Inflammatory Bowel Disease: A Qualitative Study in East China.","authors":"Fen Xu, Jingjing Xing, Mingna Fan, Zhiping Zhu, Yan Chen, Wen Hu, Yunxian Zhou","doi":"10.2147/PPA.S486974","DOIUrl":"10.2147/PPA.S486974","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the factors impacting medication non-adherence in patients with inflammatory bowel disease (IBD) in China, and to provide a reference for effective interventions.</p><p><strong>Patients and methods: </strong>Individual semi-structured interviews were conducted between December 2020 and July 2021 in four tertiary hospitals in East China. A conventional content analysis method was used in data analysis to extract themes and sub-themes in IBD Patients with poor medication adherence.</p><p><strong>Results: </strong>The 10 participants included were those who were diagnosed with IBD at least 1 year and could provide rich information and express strong desire. Seven themes emerged after data analysis: (a) non-acceptance of disease; (b) Lack of cognition of disease; (c) medication beliefs; (d) perceived efficacy; (e) Forgetting and delays; (f) costs of medication; (g) personality and psychological factors.</p><p><strong>Conclusion: </strong>Our data confirmed that in addition to comprehensive disease education and effective communication, medical staff should also pay attention to individualized factors, and develop effective response strategies for medication management support to reduce recurrence and control the disease.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2481-2494"},"PeriodicalIF":2.0,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients' Preferences for the Treatment of a Single Missing Tooth in China: A Discrete Choice Experiment.","authors":"Ming-Yu Zhao, Wen Zeng, Sze Ngai Chan, Jianhao Du, Naman Rao, Taoran Liu, Wai-Kit Ming","doi":"10.2147/PPA.S475061","DOIUrl":"10.2147/PPA.S475061","url":null,"abstract":"<p><strong>Purpose: </strong>The main treatment options offered to patients to choose from when restoring a single missing tooth include tooth-supported three-unit fixed partial dentures (FPDs) and implant-supported single crowns (ISCs). However, due to the heterogeneity of current studies, it is difficult to objectively compare these two treatment strategies. In this study, a discrete choice experiment (DCE) was used to quantify the preferences of individuals undergoing restoration treatment for single tooth loss.</p><p><strong>Patients and methods: </strong>The DCE questionnaire was disseminated in a \"snowball\" fashion, with data collected from participants aged 18-60. Five important attributes of treatment were selected: (1) treatment procedure, (2) treatment time, (3) cost, (4) five-year survival rate, and (5) five-year complication rate. A conditional logit model was employed to ascertain the direction of participants' preferences for specific attribute levels and to derive their willingness to pay (WTP) through the principle of marginal utility.</p><p><strong>Results: </strong>287 participants completed the questionnaire. The results of the questionnaire revealed that the five-year complication rate (42.42%) was the most important attribute, followed by cost (20.43%), five-year survival rate (14.23%), treatment time (13.44%), and treatment procedure (9.49%). Participants were willing to pay RMB$11076.2 (USD$1,772.2) to obtain a 10% extra reduction in the five-year complication rate, and RMB$7434.6 (USD$1,189.5) for a non-invasive treatment.</p><p><strong>Conclusion: </strong>In the ranking of the relative importance of key factors affecting single missing tooth restoration, complication rates are most highly valued, suggesting that reducing the complication rate is a key issue to be addressed in prosthodontics. In addition, deriving the ranking of patients' concerns about key factors can help to improve doctor-patient communication and provide a reference for treatment technology development and medical decision-making.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2455-2467"},"PeriodicalIF":2.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hierarchical Medical: What are the Factors Driving ESKD Patients to Choose Community Hemodialysis Centers in China? A Labelled Discrete Choice Experiment.","authors":"Juyang Xiong, Hangjing Zhang, Huimin Ma","doi":"10.2147/PPA.S484608","DOIUrl":"10.2147/PPA.S484608","url":null,"abstract":"<p><strong>Purpose: </strong>In China, secondary and tertiary hospital-based dialysis facilities had been the most prominent provider of hemodialysis treatment. Developing community hemodialysis centers was the key to constructing hierarchical hemodialysis system. Thus, the aim of this study was to explore end-stage kidney disease (ESKD) patients' preferences for hemodialysis services and attract patients with stable condition to choose community hemodialysis services.</p><p><strong>Patients and methods: </strong>The study used a labelled discrete choice experiment with ESKD patients in Wuhan, Hubei Province in China. Patients were asked to make a choice between hospital-based hemodialysis facilities and community hemodialysis centers with different attribute levels. Mixed logit model was used to measure their preferences and heterogeneity for hemodialysis services. The marginal utility was measured to predict the change of patients' choice probability of community hemodialysis centers.</p><p><strong>Results: </strong>A total of 420 ESKD patients consented to complete the questionnaires and 408 were included in the analysis after excluding responses that did not pass the consistency test. All attributes were significantly influencing respondents' choice of hemodialysis service. Patients were more inclined to hemodialysis services with smooth and effective referral, regular doctors, 20 minutes of travel time, and home-based offline follow-up. Gender, age, income, hemodialysis year, and hemodialysis times weekly were found to influence the preferences. When the community hemodialysis service attributes gradually meet the patients' preferences, as many as 58.39% of patients will choose community hemodialysis centers.</p><p><strong>Conclusion: </strong>A better understanding of ESKD patients' preferences for hemodialysis service is a crucial step for the future policy implementations. Although patients tended to choose hospital-based hemodialysis facilities, patients' preferences for hemodialysis institutions would reverse with the change of service attribute. Establishing a smooth and effective referral is the most important attribute to improve patients' acceptance of community hemodialysis centers. Strengthening the integration of service can facilitate hierarchical hemodialysis service system.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2441-2454"},"PeriodicalIF":2.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Barriers to Healthy Lifestyle Adherence and Associated Factors Among Patients with Type 2 Diabetes Mellitus: Implications for Improved Self-Care.","authors":"Awatif M Alrasheeday, Hasna Sumir Alshammari, Bushra Alshammari, Sameer A Alkubati, Jordan H Llego, Azizah Dhaher Alshammari, Matar Hamed Alshammari, Ruqayyah Abdullah Almohammed, Saad Mohammed Saad Alsheeb, Farhan Alshammari","doi":"10.2147/PPA.S432806","DOIUrl":"10.2147/PPA.S432806","url":null,"abstract":"<p><strong>Background: </strong>Many patients with type 2 diabetes mellitus (T2DM) face barriers to maintain a healthy lifestyle. This study investigated the perceived barriers to healthy eating and physical activity and compared them by demographic and diabetes-related characteristics among patients with T2DM.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 534 patients with T2DM attending primary healthcare centers in Hail City from January to June 2023. Data analyzed at a significance level of <0.05.</p><p><strong>Results: </strong>Barriers to healthy eating and physical activity were perceived by 34.9% and 28% of patients, re-spectively. Personal and environmental barriers to healthy eating were perceived more frequently than social barriers (43.0% and 26.9%, respectively). Personal and environmental barriers to physical activity were perceived by 28.0% of patients, followed by social barriers (27.9%). The most frequently perceived barrier to healthy eating was a lack of motivation (61.6%), followed by insufficient information about healthy diets (32.2%). Regarding physical activity, a lack of motivation was the most frequently perceived personal barrier (32.0%), while a lack of a supportive work environment was the most frequently perceived social barrier (33.7%). Patients who were aged between 30 and 40 years, were highly educated, were diagnosed with DM within less than five years, and used insulin injections as a strategy to manage DM reported significantly higher levels of perceived barriers to healthy eating compared to their counterparts. In contrast, patients who were female, married, had poor financial status, and used insulin injections reported significantly higher levels of perceived barriers to physical activity compared to their counterparts.</p><p><strong>Conclusion: </strong>Over one-third of patients with T2DM seeking medical care in Hail City perceive barriers to healthy eating, mainly a lack of motivation, insufficient diet information. Educational programs that consider the unique characteristics of patients should be developed.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2425-2439"},"PeriodicalIF":2.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"People Living with Chronic Obstructive Pulmonary Disease (COPD) and Inhalers: Insights and Suggestions from a Human Factors Study on NEXThaler.","authors":"Nicola Scichilone, Andrew Whittamore, Chris White, Elena Nudo, Massimo Savella, Marta Lombardini","doi":"10.2147/PPA.S483993","DOIUrl":"10.2147/PPA.S483993","url":null,"abstract":"<p><strong>Purpose: </strong>COPD treatment relies mostly on drug administration via inhaler. Adherence to therapy is highly dependent on inhaler features and patient training. With the aim of identifying patients' unmet needs and expectations about inhalers, data from a recent human factors study involving COPD patients have been analyzed. The specific use of the NEXThaler, a multidose dry powder inhaler that is activated by the patient's inhalation, and its potential impact on adherence was explored.</p><p><strong>Methods: </strong>Adult patients with moderate to severe COPD were interviewed across 8 European countries using 90-minute semi-structured interviews to assess symptoms, services, challenges, patient expectations, and feedback on current inhalers. Patients participated in a simulation of NEXThaler use and watched a training video; they were asked to rate the device's key features regarding treatment experience, confidence, and quality of life and provide suggestions for improvement.</p><p><strong>Results: </strong>The 62 patients interviewed most appreciated an inhaler's ease of use, followed by the presence of an inhalation counter and a comfortable mouthpiece. Some patients were more interested in the drug itself rather than in the delivery device. Overall, the participants had positive feedback about NEXThaler, appreciating its ease of use, the low inhalation effort required to activate it, and the presence of both the inhalation click (referred to as the \"click of confidence\" because it gives COPD patients confidence that the dose has been released correctly) and the inhalation counter.</p><p><strong>Conclusion: </strong>NEXThaler has been appreciated for its three differentiating features (click of confidence, low inhalation effort, and inhalation counter), which have been shown to have a positive impact on patient's lives, treatment experience, and confidence. This can potentially translate into improved medication adherence with a positive impact on the QoL of people living with COPD.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2415-2423"},"PeriodicalIF":2.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Adherence to Health Behaviors Research: Reflections on Current Methods and Future Directions [Response to Letter].","authors":"Siying Ji, Anan Li, Yangfan Nie, Yunying Hou","doi":"10.2147/PPA.S507647","DOIUrl":"10.2147/PPA.S507647","url":null,"abstract":"","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2395-2396"},"PeriodicalIF":2.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Sensor-Based Interventions for Supporting Patient Adherence to Inhalation Therapy.","authors":"Jing Ma, Xu Sun, Bingjian Liu","doi":"10.2147/PPA.S485553","DOIUrl":"10.2147/PPA.S485553","url":null,"abstract":"<p><strong>Purpose: </strong>This review aims to provide a comprehensive overview of sensor technologies employed in interventions to enhance patient adherence to inhalation therapy for chronic respiratory diseases, with a particular emphasis on human factors. Sensor-based interventions offer opportunities to improve adherence through monitoring and feedback; however, a deeper understanding of how these technologies interact with patients is essential.</p><p><strong>Patients and methods: </strong>We conducted a systematic review by searching online databases, including PubMed, Scopus, Web of Science, Science Direct, and ACM Digital Library, spanning the timeframe from January 2014 to December 2023. Our inclusion criteria focused on studies that employed sensor-based technologies to enhance patient adherence to inhalation therapy.</p><p><strong>Results: </strong>The initial search yielded 1563 results. After a thorough screening process, we selected 37 relevant studies. These sensor-based interventions were organized within a comprehensive HFE framework, including data collection, data processing, system feedback, and system feasibility. The data collection phase comprised person-related, task-related, and physical environment-related data. Various approaches to data processing were employed, encompassing applications for assessing intervention effectiveness, monitoring patient behaviour, and identifying disease risks, while system feedback included reminders and alerts, data visualization, and persuasive features. System feasibility was evaluated based on patient acceptance, usability, and device cost considerations.</p><p><strong>Conclusion: </strong>Sensor-based interventions hold significant promise for improving adherence to inhalation therapy. This review highlights the necessity of an integrated \"person-task-physical environment\" system to advance future sensor technologies. By capturing comprehensive data on patient health, device usage patterns, and environmental conditions, this approach enables more personalized and effective adherence support. Key recommendations include standardizing data integration protocols, employing advanced algorithms for insights generation, enhancing interactive visual features for accessibility, integrating persuasive design elements to boost engagement, exploring the advantages of conversational agents, and optimizing experience to increase patient acceptance.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2397-2413"},"PeriodicalIF":2.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Patients' Knowledge on the Disease and Its Management with Indicators of Disease Severity and Individual Characteristics in Patients with Chronic Obstructive Pulmonary Disease (COPD): Results from COSYCONET 2.","authors":"Carolina Fischer, Maria Siakavara, Peter Alter, Claus Franz Vogelmeier, Tim Speicher, Hendrik Pott, Henrik Watz, Robert Bals, Franziska Trudzinski, Felix Herth, Joachim H Ficker, Manfred Wagner, Christoph Lange, Krista Stoycheva, Winfried Randerath, Jürgen Behr, Sebastian Fähndrich, Tobias Welte, Isabell Pink, Kathrin Kahnert, Werner Seeger, Stefan Kuhnert, Tobias Gessler, Nina Adaskina, Rudolf A Jörres","doi":"10.2147/PPA.S488165","DOIUrl":"10.2147/PPA.S488165","url":null,"abstract":"<p><strong>Background: </strong>In patients with chronic diseases, including those with chronic obstructive pulmonary disease (COPD), knowledge on the disease and its self-management is considered as relevant for improving disease control and long-term outcome. We studied to which extent components of knowledge depended on potential predictors, such as participation in educational programs and disease severity. For example, the perception of exacerbations or GOLD grade might modulate the content and reliability of COPD understanding.</p><p><strong>Methods: </strong>Data from the German COSYCONET 2 COPD cohort was used, and 13 questions addressing knowledge and self-management were analyzed.</p><p><strong>Results: </strong>Overall, 310 patients with the diagnosis of COPD of GOLD grades 1/2/3/4 as well as the former grade 0 were included (39.7% female, median age 66.0 years). The answers to 3 questions (knowledge of term exacerbation, pursed lip breathing technique, criteria for contacting a doctor) were improved (p < 0.05 each) when patients had had moderate-to-severe exacerbations, and to one question (breathing exercise) when having COPD grade 3/4 versus 0/1/2. The other 9 responses did not depend on disease severity, but most of the knowledge was improved when having participated in an educational COPD program. This was particularly true for knowledge that also depended on exacerbations, or if the treating physician was a pulmonary specialist. In some responses, the proportion of correct answers was significantly reduced in males compared to females. The dependence on education level, existence of a treatment plan, self-reported level of risk aversion and low depression score was weak and heterogeneous.</p><p><strong>Conclusion: </strong>These findings suggest that part of the disease-related knowledge in patients with COPD was reinforced by the experience of exacerbations, especially knowledge regarding criteria on contacting a physician. These observations might help in focusing education on those parts of knowledge that are considered as important by patients based on their own experience.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2383-2393"},"PeriodicalIF":2.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}