Patient preference and adherence最新文献

{"title":"Doctor-Patient Communication Models, Patient Decision-Making Participation, and Patient Emotional Expression: A Cross-Cultural Comparison of Samples from the UK and China.","authors":"Chao Liu, Ye-Hui Tu, Li-Jen Lin, Hao Chen, Thu-Hua Liu, Huang-Li Lin, Renbo Liu, Wen-Ko Chiou","doi":"10.2147/PPA.S537829","DOIUrl":"10.2147/PPA.S537829","url":null,"abstract":"<p><strong>Background: </strong>Effective doctor-patient communication is critical to healthcare outcomes, but cultural differences can significantly influence communication dynamics. Understanding how cultural factors shape communication styles is essential, particularly in cross-cultural healthcare settings. Power distance and individualism/collectivism are key cultural dimensions that may impact doctor-patient interactions.</p><p><strong>Objective: </strong>This study aims to examine the impact of cultural differences between China and the UK on doctor-patient communication, focusing on communication quality, patient participation in decision-making, and emotional expression.</p><p><strong>Methods: </strong>A total of 1000 participants (500 from China and 500 from the UK) were surveyed using four measurement tools: the Doctor-Patient Communication Scale (DPCS), the Hofstede Cultural Dimensions Questionnaire (HCDQ), the Patient Participation in Decision-Making Scale (PPDMS), and the Emotional Expression in Healthcare Scale (EEHS). The data were analyzed using independent samples <i>t</i>-tests, Pearson correlation, and regression analysis.</p><p><strong>Results: </strong>The findings reveal significant cultural differences between China and the UK in terms of communication quality, patient participation, and emotional expression. British patients reported significantly higher scores on all scales, reflecting the more egalitarian and individualistic communication style in the UK compared to the more hierarchical and collectivist style in China. Power distance and individualism/collectivism were significant predictors of communication outcomes, with higher power distance and stronger collectivism associated with lower communication quality, reduced patient participation, and more restrained emotional expression.</p><p><strong>Conclusion: </strong>Cultural dimensions significantly affect doctor-patient communication, highlighting the importance of considering cultural differences in healthcare settings. This study underscores the need for tailored communication strategies that accommodate cultural norms to improve patient engagement and healthcare outcomes across different cultural contexts. Future research should address the limitations of this study, including its reliance on self-reported data, and explore additional cultural contexts to better understand the complexities of cross-cultural healthcare communication.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2505-2524"},"PeriodicalIF":2.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144964731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 Pandemic on Adherence to Most Costly Chronic Disease Medications in British Columbia, Canada: A Population-Based Interrupted Time Series Analysis.","authors":"Nevena Rebić, Eric C Sayre, Michael R Law, Jacquelyn J Cragg, Lori A Brotto, Mary A De Vera","doi":"10.2147/PPA.S529666","DOIUrl":"10.2147/PPA.S529666","url":null,"abstract":"<p><strong>Purpose: </strong>To address limited population-level data on prescription medication taking during COVID-19, we assessed the impact of the pandemic on adherence to the costliest drug classes prescribed for chronic diseases in British Columbia (BC).</p><p><strong>Patients and methods: </strong>Of the 100 top drug classes contributing to total drug spending in 2020, we categorized those prescribed for chronic diseases into 26 drug groups; specifically, drugs for psychiatric and neurologic, cardiac and respiratory, hormone-related, and immune and musculoskeletal conditions. Using administrative health data on all dispensed medications, we quantified adherence by monthly proportion of days covered (PDC) and performed interrupted time-series analysis (ITS) to estimate changes in PDC trends 1-year before and after the implementation of pandemic mitigation measures.</p><p><strong>Results: </strong>We included 3,906,377 adults with ≥1 prescription to ≥1 included drug groups. The most common prescriptions among our study population were for antidepressants (45.0%), drugs for obstructive airway diseases (41.6%), renin-angiotensin system agents (30.5%), diuretics (28.2%), and lipid modifying agents (24.8%). ITS models for 22 of 26 drug groups showed statistically significant changes in monthly PDC trends, with the greatest change occurring among parenteral immunosuppressants, injectable insulins and analogues, and renin-angiotensin system agents.</p><p><strong>Conclusion: </strong>Findings suggest that the pandemic did not substantially impact adherence to commonly used medications; however, adherence was found to be suboptimal across all drug groups regardless of the impact of COVID-19. Medication adherence remains a critical therapeutic challenge requiring our attention irrespective of major healthcare system stressors such as COVID-19.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2493-2504"},"PeriodicalIF":2.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144964734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Experience and Improvement Opportunities in Self-Administered, Large-Volume Subcutaneous Infusions at Home.","authors":"Chris Franzese, James Hawthorne, Dimos Katsaros, Marty Coyne","doi":"10.2147/PPA.S515565","DOIUrl":"10.2147/PPA.S515565","url":null,"abstract":"<p><strong>Purpose: </strong>Subcutaneous (SC) administration is largely established as the preferred route to deliver biotherapeutics. Although the majority of approved SC products are limited to dose volumes ≤2.25 mL, there has been increasing industry focus on large-volume SC (LVSC) development. To date, however, there are few LVSC biotherapeutics available for self-administration, and subcutaneous immunoglobulin (SCIg) remains the most established example. As a result, there is limited published literature on real-world practices with LVSC therapies to inform user needs and preferences for delivery device design attributes.</p><p><strong>Patients and methods: </strong>This was a remote ethnography study of patients self-administering SCIg at home for treatment of primary immunodeficiency diseases (PIDD). Participants passively video recorded their preparation and infusion processes, took photos, and provided open responses to illustrate their overall experiences with their disease, infusions, and delivery devices. Qualitative data were compiled, analyzed, and grouped into themes and subthemes that represented participant responses and sentiments.</p><p><strong>Results: </strong>A total of 11 patients completed the remote study, all of whom were diagnosed with PIDD. Enrolled participants were currently infusing SCIg with one of five delivery devices and most also had previous experience with another delivery device. Emerging themes included universal preference for SC administration and pain points associated with managing medication/supply orders, storing medications/supplies, troubleshooting device issues, performing burdensome medication preparations, priming tubing/needles, inserting/securing needles, programming devices, adapting to device volume constraints, and loading reservoirs or tubing into delivery devices.</p><p><strong>Conclusion: </strong>Although patients prefer LVSC administration at home compared to the alternatives, the current SCIg use process presents a variety of challenges. While not all of these factors will apply to every LVSC scenario, these insights, along with their corresponding implications for device design, provide a framework to inform user needs for LVSC self-administration, anticipate obstacles during development of new LVSC therapies, and improve existing delivery devices.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2459-2491"},"PeriodicalIF":2.0,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Primary Chronic Immune Thrombocytopenia and Thrombopoietin Receptor Agonists Treatment Instructions on Daily Living: Results of a Multinational Cross-Sectional Survey.","authors":"Jaap Jan Zwaginga, Srikanth Nagalla, Marie Linden, Marjo Hannele Lindberg, Caroline Kruse, Mervyn Morgan, Cecilie Yssing, Donatella Decise, Milica Putnik, Carly Rich","doi":"10.2147/PPA.S505337","DOIUrl":"10.2147/PPA.S505337","url":null,"abstract":"<p><strong>Purpose: </strong>Thrombopoietin receptor agonists (TPO-RAs) are second-line treatments for people with immune thrombocytopenia (ITP). A survey was conducted to evaluate the understanding of and adherence to TPO-RA treatment instructions, and to determine the impact of ITP and TPO-RAs on daily living.</p><p><strong>Patients and methods: </strong>Cross-sectional, self-administered, online survey conducted from September 2023 to April 2024. Respondents were aged ≥18 years, diagnosed with primary chronic ITP, and prescribed a TPO-RA in the last 12 months and for ≥3 months.</p><p><strong>Results: </strong>In total, 221 respondents were voluntarily recruited by patient organizations and completed the survey. Over one-third (37%) of respondents were given ≥5 specific instructions on medication use (eltrombopag 58%; avatrombopag 24%; romiplostim 9%). Taking treatment at the same time each day/week was most common. Eltrombopag-treated respondents were given the most instructions about food: timing of medication relative to meals (72%), timing of meals relative to medication (65%), and the restriction (44%) or avoidance (69%) of certain foods. Despite this, nearly one-third (32%) of eltrombopag-treated respondents ate when/what they wanted at times, and 64% would prefer to have a TPO-RA with no food/drink restrictions. Compared to before ITP diagnosis, living with ITP negatively impacted ≥1 daily activity or mental health in 89% of respondents, most commonly travelling (for pleasure [69%]). Approximately one-third (36%) experienced an improvement or no change in ≥1 daily activity or mental health after TPO-RA treatment initiation. Eating habits, sleeping, exercise/sport and mental health were markedly worsened by treatment with a TPO-RA. Avatrombopag and eltrombopag had the highest rates of any reported improvements across daily activities/mental health.</p><p><strong>Conclusion: </strong>This real-world international survey showed that people with ITP may experience a negative impact on their daily activities and mental health from their condition. Treatment with some TPO-RAs may also impair specific activities, likely influenced by administration routes and dietary restrictions.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2445-2458"},"PeriodicalIF":2.0,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"I Probably Am Being a Naughty Boy, But…\" Reasons for Non-Adherence to Prescribed Medication, as Perceived by People Living with Inflammatory Bowel Disease: A Qualitative Study.","authors":"Kathryn King, Christine Norton, Awa Jammeh, Trudie Chalder, Wladyslawa Czuber-Dochan","doi":"10.2147/PPA.S531675","DOIUrl":"10.2147/PPA.S531675","url":null,"abstract":"<p><strong>Purpose: </strong>Inflammatory bowel disease (IBD) is treated with medications to induce and maintain remission. However, many people with IBD do not take treatments as prescribed. Identifying and understanding reasons behind medication non-adherence in IBD is critical.</p><p><strong>Patients and methods: </strong>Semi-structured interviews were recorded and transcribed verbatim. Braun and Clarke's principles of reflexive thematic data analysis were followed.</p><p><strong>Results: </strong>Twenty people living with IBD were purposively selected and interviewed. Four main themes were identified: 1) Context: adherence was impacted by the context of care individuals received, daily activities, physical and emotional well-being and relationship with others; 2) Battles: with IBD, with healthcare professionals and/or with IBD medication; 3) Medical treatment: treatment type, efficacy, side-effects and treatment requirements influenced adherence, as did an individual's treatment beliefs; and 4) Knowledge, learning, understanding and experience of IBD as a condition and its treatment typically promoted adherence. Yet treatment information was frequently not offered by healthcare professionals, leading individuals to self-educate and develop personal understanding, which with experience, influenced their adherence, both positively and negatively.</p><p><strong>Conclusion: </strong>Medication adherence is a journey, influenced by multiple determinants. IBD diagnosis is a critical stage where individuals require compassionate care from both multidisciplinary health professionals and personal networks. Clear treatment information should be provided, with self-education encouraged through trusted resources. To promote adherence and establish treatment routines, patients must feel fully informed, confident and comfortable in their shared decision-making on treatment that will suit their lifestyle.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2391-2415"},"PeriodicalIF":2.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12371128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144964647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating Adherence to Asthma Management with an Electronic Monitoring System.","authors":"Yi-Ying Liu, Han-Pin Kuo, Mei-Chuan Chen, Hsiu-Mei Chang, Shu-Chuan Ho","doi":"10.2147/PPA.S526063","DOIUrl":"10.2147/PPA.S526063","url":null,"abstract":"<p><strong>Background: </strong>Adherence to prescribed inhaler use is critical for effective asthma management and to prevent exacerbations. However, overall adherence to inhaler use among asthma patients is low and the most frequent measures of adherence are considered not sufficiently reliable. The aim of this study was to investigate adherence rates and their impact on asthma management via an electronic monitoring system.</p><p><strong>Methods: </strong>This was a prospective observational study of adults diagnosed with asthma who were equipped with electronic monitoring sensors whose data were recorded from August 2019 to June 2020. The study participants were also divided into two groups: allergic and nonallergic. The study lasted 90 days, and participants' demographic information, inhaled corticosteroid (ICS) dosage, lung function and asthma control test scores, blood samples, exhaled nitric oxide concentrations, and inhaler usage records from the electronic monitoring system were collected.</p><p><strong>Results: </strong>In total, 39 asthma patients completed the follow-up period. The study results revealed a significant difference in the adherence rates between the allergy and nonallergy groups at 30 days, with respective adherence rates of 49.9% and 22.8%, and at 90 days, the rates were 37.3% in the allergy group and 19.3% in the nonallergy group. The study results also revealed a significant positive correlation between medication adherence and the allergy group, and adherence was negatively correlated with the ICS dosage.</p><p><strong>Conclusion: </strong>In this study, the average medication adherence rates among asthma patients were low and even lower in the nonallergy group than in the allergy group. Electronic monitoring can provide a clearer understanding of patients' medication patterns and could serve as a valuable tool for improving asthma management in the future.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2417-2427"},"PeriodicalIF":2.0,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Dimensions and Items for a Questionnaire to Assess Medication Adherence in Men and Women with Ischemic Heart Disease: Insights from the GENADHECAR Study.","authors":"Álvaro Carbonell-Soliva, Rauf Nouni-García, Jose A Quesada, Francisco González-Llopis, Alberto Cordero, Vicente Bertomeu-González, Domingo Orozco-Beltrán, José Verdú-Soriano, Andreu Nolasco, Virtudes Pérez-Jover, Jose Joaquín Mira, Adriana López-Pineda, Silvia Guillén-García, Pablo Martínez-Pérez, Concepción Carratalá-Munuera, Vicente F Gil-Guillén","doi":"10.2147/PPA.S516285","DOIUrl":"10.2147/PPA.S516285","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to identify dimensions and items for a future questionnaire aimed at measuring medication nonadherence in people with ischemic heart disease, considering gender differences and incorporating the views of healthcare professionals, researchers, and patients.</p><p><strong>Patients and methods: </strong>We conducted a mixed-method cross-sectional study at San Juan de Alicante University Hospital and Miguel Hernández University (Spain). The methods used to identify dimensions included a consensus group of healthcare and scientific professionals, an open-response survey for community pharmacists, a closed-response patient survey, and patient focus groups. When drafting the item list, we followed international recommendations related to the number and wording of items. Our study also included a qualitative review of the item list and response scales by psychologists.</p><p><strong>Results: </strong>The resulting item list includes 41 potential items grouped into 26 dimensions and five domains: \"patient\", \"treatment\", \"disease\", \"health professional-patient relationship\" and \"healthcare system\". It covers aspects such as personal beliefs, mood, polypharmacy, disease symptoms, patient-healthcare professional interaction and healthcare system factors. Response options are presented on a 5-point Likert scale, including agreement-level responses and frequency-level responses.</p><p><strong>Conclusion: </strong>With the collaboration of patients, researchers, and healthcare providers, we potentially identified five domains, 26 dimensions, and 41 items with 5-point Likert scale response options. These will be considered in the subsequent development and validation of a questionnaire to measure medication adherence in patients with ischemic heart disease.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2429-2444"},"PeriodicalIF":2.0,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Qualitative Study of Migraine Headache Experience in Patients with Patent Foramen Ovale Based on the Symptom Management Theory.","authors":"Meng Li, Min Feng, Mengtian Li, Junfan Wei, Shen Li, Ning Zhang, Qiong Li, Ruipeng Song, Huawei Li","doi":"10.2147/PPA.S531129","DOIUrl":"10.2147/PPA.S531129","url":null,"abstract":"<p><strong>Objective: </strong>To explore the migraine experience of patients with patent foramen ovale (PFO) and migraine based on the Symptom Management Theory(SMT).</p><p><strong>Methods: </strong>A qualitative research approach was employed to conduct face-to-face, semi-structured, in-depth interviews with 16 patients diagnosed with PFO and migraine at the Department of Cardiology, The Third People's Hospital of Henan Province, from March to June 2025. The collected data were analyzed using the Colaizzi phenomenological method.</p><p><strong>Results: </strong>The migraine experience of patients with PFO was categorized into 3 main themes: 1) Symptom Perception: Variability in migraine severity and frequency (mean VAS 5.2 ± 1.8, indicating moderate symptom severity); Triggers and warning signs of migraine attacks; Impact of environmental and lifestyle factors on symptom onset. 2) Symptom Management: Persistent efforts to alleviate migraine symptoms (eg, medication, lifestyle adjustments); Emotional and psychological coping strategies; High expectations and hopes for the PFO closure procedure; Concerns and uncertainties about the effectiveness of the operation. 3) Symptom Outcomes: Physical and mental health challenges caused by chronic migraines; Social and occupational disruptions due to migraine symptoms; Seeking professional medical and psychological support; Long-term adaptation and resilience strategies.</p><p><strong>Conclusion: </strong>This study, grounded in the SMT, provides valuable insights into the migraine experiences of patients with PFO. The findings highlight the multifaceted nature of their symptom perception, management, and outcomes, emphasizing the profound physical, emotional, and social impact of chronic migraines on their lives. Patients' persistent efforts to manage symptoms, coupled with their high expectations for the PFO closure procedure, underscore the need for comprehensive, patient-centered care.The study also reveals the critical role of professional support in addressing both the physical and psychological dimensions of migraine management. Healthcare providers should prioritize personalized, multidisciplinary approaches to care, focusing on symptom relief, emotional well-being, and long-term adaptation strategies. Future research should expand the scope to include diverse geographical populations and explore long-term postoperative experiences to further enhance understanding and improve clinical interventions for this patient group.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2363-2375"},"PeriodicalIF":2.0,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influencing Factors of Self-Management Behavior in Patients with Glaucoma in West China: A Cross-Sectional Study.","authors":"Xin Zhang, Jie Ren, Li Tang, Ji-Hong Zeng, Jing Tang","doi":"10.2147/PPA.S528222","DOIUrl":"10.2147/PPA.S528222","url":null,"abstract":"<p><strong>Background: </strong>Glaucoma is the world's leading cause of irreversible blindness, and poor self-management behavior is a global public health problem. Effective self-management behavior is crucial for controlling the progression of the disease. Nevertheless, few studies have carried out large-sample research on the factors influencing self-management behavior in glaucoma patients. The aim of this study was to comprehend the influencing factors of self-management behavior in glaucoma patients in western China and to provide a scientific basis for further exploring the intervention measures to enhance self-management behavior.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at West China Hospital, Sichuan University. It enrolled 538 participants from 12 provinces, municipalities, and autonomous regions across western China via convenience sampling. Survey instruments included: 1) a self-developed general information questionnaire (covering demographic and disease-related data); 2) the Glaucoma Self-Management Questionnaire (GSMQ); 3) the Social Support Rating Scale (SSRS); and 4) the Brief Illness Perception Questionnaire (BIPQ).</p><p><strong>Results: </strong>The mean total score of the glaucoma self-management questionnaire was 50.64±6.06. The mean total score of the social support rating scale was 31.04±7.65. The mean total score on the brief illness perception questionnaire was 47.65±7.33. Patients with glaucoma identified various contributing factors to their condition, with emotion ranking highest at 29.4%, followed by stress at 22.5%, and genetics at 18.2%. Multivariate analysis showed that smoking, type of glaucoma, annual follow-up frequency, assignment of a follow-up doctor, social support, and illness perception significantly affected self-management behaviors (P<0.05).</p><p><strong>Conclusion: </strong>Self-management behaviors, social support and disease perception of glaucoma patients are all at a moderate level. Smoking, less than two annual follow-ups, primary open-angle glaucoma and not having a designated follow-up doctor are all associated with poorer self-management behaviors. A higher level of social support is associated with improved self-management behavior. Patients who perceived greater harm to their physical wellbeing due to the disease tended to show poorer self-management behavior.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2377-2389"},"PeriodicalIF":2.0,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Patient Perspectives in Treatment and Management of Care in Asthma.","authors":"Alexandra Hicks, Michael J George, Mason Benjamin, Eric Lacoste, Hilarry C Orr, Angel Melendez, Donna D'laine Gardner","doi":"10.2147/PPA.S522436","DOIUrl":"10.2147/PPA.S522436","url":null,"abstract":"<p><strong>Purpose: </strong>For the development of novel and efficacious drugs and improvement of patients' quality of life, the involvement of patient stakeholders in drug development is essential. This study was conducted among patients with asthma to understand their unmet needs with current treatments, and expectations from new treatments.</p><p><strong>Methods: </strong>Sanofi collaborated with the Allergy & Asthma Network (AAN), a US-based patient advocacy group and their patient community. Several virtual patient panels were conducted involving patient advocates and researchers that spanned patient experiences with asthma, treatment options, gaps, needs, and priorities. Additionally, a literature search was conducted using Medline^® between July 2013 and July 2023.</p><p><strong>Results: </strong>Based on input gleaned from patients (n=5), their major unmet needs included: management of medication-related side effects, lack of information about correct inhaler techniques, medication costs, misunderstanding of medication dosing schedules, lack of communication between researchers and patients, lack of awareness about patient advocacy organizations and research led programs, and fear of discrimination or having concerns disregarded by healthcare providers. Patients expressed their expectation that new treatments should treat all asthma symptoms, including inflammation, airway constriction, and responsiveness to asthma triggers, all with a single treatment. For patients, an ideal treatment would not need to be taken daily, would be quick-acting, and cost-effective for all patients regardless of their insurance status or coverage. Digital applications that remind patients to take their medications on schedule and monitor asthma triggers, mood, sleep, peak flow recordings, and nutrition could improve patients' treatment adherence, quality of life, and health outcomes would be welcomed.</p><p><strong>Conclusion: </strong>This study emphasizes the importance of gathering input from patients living with asthma, understanding their unmet needs, and the importance of integrated patient engagement in the development of new therapies for asthma.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2353-2361"},"PeriodicalIF":2.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12348883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144848258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}