Patient preference and adherence最新文献

{"title":"Knowledge, Attitude, and Practice Toward Hallux Valgus Among Women: A Web-Based Cross-Sectional Study.","authors":"Delong Gao, Tao Fu, Weitao Dai, Guangwu Liu","doi":"10.2147/PPA.S535333","DOIUrl":"10.2147/PPA.S535333","url":null,"abstract":"<p><strong>Purpose: </strong>Hallux valgus is a common foot deformity affecting primarily adults and the elderly, especially females, resulting in significant changes in foot architecture and function. This study aimed to investigate the knowledge, attitudes, and practices (KAP) regarding hallux valgus among women.</p><p><strong>Patients and methods: </strong>Between July and August 2023, a self-administered questionnaire was utilized to collect demographic data along with KAP scores from 526 women, 291 (55.32%) of whom were over 30 years of age.</p><p><strong>Results: </strong>The mean scores were 7.04 ± 2.25 for knowledge (range: 0-10), 36.24 ± 2.98 for attitude (range: 11-55), and 25.02 ± 4.90 for practice (range: 7-35). Multivariate logistic regression identified knowledge (OR = 1.335, 95% CI: 1.213-1.469, P < 0.001), age over 30 years (OR = 1.517, 95% CI: 1.026-2.244, P = 0.037), monthly income above 10,000 Yuan (OR = 1.638, 95% CI: 1.111-2.415, P = 0.013), and mild hallux valgus (OR = 1.974, 95% CI: 1.246-3.127, P = 0.004) as independently linked to proactive practices. Additionally, the structural equation model indicated a direct effect of knowledge on practice (β = 0.765, P < 0.001).</p><p><strong>Conclusion: </strong>Women showed adequate knowledge but suboptimal attitudes and proactive practices concerning hallux valgus. Enhancing patient education is vital for improving understanding and addressing misconceptions regarding this condition.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2343-2352"},"PeriodicalIF":2.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144837227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydroquinone Levels in Unregulated Skin-Lightening Creams and Women's Knowledge, Attitudes, and Practices Toward Skin-Lightening Products in Hail, Saudi Arabia.","authors":"Farhan Alshammari, Fawaz Alheibshy, Ahmed Alobaida, Mohammed Qaed Alhamad, Othman Abdulrahman Alrashidi, Omar Raja Alharbi, Azizah Dhaher Alshammri, Matar Hamed Alshammari, Laila Lafi Alharbi, Hamad Ahmad Almarri, Abdullah Fahad Altihani, Abdulrahman Ibrahim Aldibas, Layla Alshammari, Bushra Alshammari","doi":"10.2147/PPA.S514993","DOIUrl":"10.2147/PPA.S514993","url":null,"abstract":"<p><strong>Background: </strong>Skin-lightening products (SLPs) are widely used in Saudi Arabia, driven by cultural ideals that associate lighter skin tones with beauty and social status. Hydroquinone (HQ), a common ingredient in skin-lightening creams (SLCs), inhibits melanin production but carries risks such as skin irritation, hyperpigmentation, and potential carcinogenicity. This study aimed to evaluate the safety of locally available SLCs and investigate consumer knowledge, attitudes, and practices (KAP) regarding SLP use in Hail, Saudi Arabia.</p><p><strong>Methods: </strong>Ten locally available SLCs samples were collected from pharmacies and cosmetic shops in Hail. HQ concentrations were analyzed using validated UV-visible spectrophotometry, while pH levels were measured to assess their safety. A cross-sectional KAP survey of 301 residents was also conducted, exploring awareness, usage habits, and reported side effects of SLPs.</p><p><strong>Results: </strong>Laboratory analysis showed that 80% of the samples contained HQ, with concentrations reaching as high as 7.1%. As HQ is classified as a prescription-only drug at any concentration in Saudi Arabia, the presence of HQ in unregulated products raises significant safety concerns. pH levels ranged from 2.92 to 10.04, with half of the samples outside the optimal skin pH range, posing concerns about irritation risks. Among survey participants, 63% reported using SLPs, primarily in cream form (91%). While 80% recognized potential risks, only half were aware of the ingredients in their products. Reported side effects included redness (18.75%) and pigmentation issues (15.33%), with 16.33% of users requiring medical care.</p><p><strong>Conclusion: </strong>These findings reveal significant safety concerns surrounding locally available SLCs, with HQ concentrations frequently exceeding permissible limits and unsuitable pH levels exacerbating risks. The widespread use of SLPs despite limited consumer awareness underscores the urgent need for stronger regulations and public education to promote safer cosmetic practices in Saudi Arabia.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2309-2318"},"PeriodicalIF":2.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12335261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Melasma Patients' Needs Through Social Media: A Qualitative Study.","authors":"Xinjin Liu, Xu Liu, Yanbing Han, Yifei Cheng, Hongjie Luo, Yichen Liu, Dingling Li, Weihong Guo, Haoyu Jiang, Linghong Guo, Xian Jiang","doi":"10.2147/PPA.S532613","DOIUrl":"10.2147/PPA.S532613","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the primary concerns and unmet needs of patients with melasma on social media using qualitative analysis and AI-based keyword extraction.</p><p><strong>Patients and methods: </strong>We conducted a qualitative study of melasma patient discussions using publicly available posts on Facebook and Baidu. The data were collected between January 2014 and October 2024. ChatGPT-4o was used for keyword extraction and classification.</p><p><strong>Results: </strong>A total of 1106 related posts were analyzed, revealing 284 unique tags and 2434 keywords. Treatment and prevention were the most discussed topics, with patients seeking information on effective, long-term, and affordable treatment. Daily care and mental health accounted for 29.2% of the total, focusing on skincare routines, sun protection, and lifestyle modification. Etiology and clinical features were observed in 14.8% of the posts, whereas 2.4% addressed diagnosis and differentiation.</p><p><strong>Conclusion: </strong>This study identified key concerns of patients with melasma using AI-based keyword extraction and qualitative analysis, highlighting the need for healthcare professionals to engage in digital patient education, clarify misinformation, support patient self-management, and integrate mental health considerations into melasma care. Future research should focus on AI-based interventions to enhance patient engagement and self-management.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2333-2341"},"PeriodicalIF":2.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relative Importance of Disease-Modifying Antirheumatic Drug Attributes for Patients with Rheumatoid Arthritis.","authors":"Nabin Poudel, Jingjing Qian, Kimberly B Garza, Peng Zeng, Jeffrey R Curtis, Surachat Ngorsuraches","doi":"10.2147/PPA.S514920","DOIUrl":"10.2147/PPA.S514920","url":null,"abstract":"<p><strong>Purpose: </strong>The significance of fatigue reduction in rheumatoid arthritis (RA) is well recognized. However, prior patient preference studies on disease-modifying antirheumatic drugs (DMARDs) have not adequately explored the relative importance of fatigue reduction compared to other DMARD attributes or accounted for preference heterogeneity. The objective of this study is to determine the relative importance of DMARD attributes, including fatigue reduction, from the patient perspective.</p><p><strong>Patients and methods: </strong>We conducted a web-based discrete choice experiment (DCE) survey among RA patients in the US. Six DMARD attributes were included: chance of pain reduced by 50% or more, chance of physical function improved by 50% or more, chance of fatigue reduced by 10 points or more, chance of serious side effects, the route and frequency of administration, and out-of-pocket cost per month. Choice sets were constructed using a Bayesian efficient design. Mixed logit (ML) and latent class (LC) models were developed to determine preference weights and to calculate the conditional relative importance of each attribute.</p><p><strong>Results: </strong>Of 228 patients, the ML model showed that the chance of pain reduction had the highest conditional relative importance (2.4), followed by out-of-pocket cost (2.1), the chance of physical function improvement (1.6), the chance of fatigue reduction (1.5), the chance of experiencing serious adverse events (0.6), and the route and frequency of administration (0.09). Preference heterogeneity was observed. The LC model identified two patient classes. The chance of fatigue reduction and the out-of-pocket cost were the most important attributes for class 1 and class 2, respectively.</p><p><strong>Conclusion: </strong>Pain reduction, physical function improvement, fatigue reduction, and out-of-pocket cost were relatively important DMARD attributes for RA patients. However, the presence of preference heterogeneity underscores the need for individualized treatment. Future studies should explore fatigue preferences and generalizability in the broader RA population.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2319-2331"},"PeriodicalIF":2.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12333635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Self-Management Care and Shared Decision-Making with Glycemic Control and Psychosocial Outcomes in Type 2 Diabetes Mellitus.","authors":"Mu'taman Jarrar, Mohammad Al-Bsheish, Bashair Khalid Alshahri, Manar Abdulrahman Bamashmoos, Mona I Alnaimi, Shaykhah A Alsayil, Shymaa A Basager, Mohammad Ahmad Al Rawashdeh, Ahmad Bahjat Al-Rawashdeh","doi":"10.2147/PPA.S534066","DOIUrl":"10.2147/PPA.S534066","url":null,"abstract":"<p><strong>Purpose: </strong>This study explored the associations of Self-Management Care (SMC) and Shared Decision-Making (SDM) with clinical outcomes, specifically glycated hemoglobin (HbA1c) levels, and non-clinical outcomes (psychosocial Outcomes) in patients with type 2 Diabetes Mellitus (T2DM).</p><p><strong>Methods: </strong>A cross-sectional design was employed, involving 200 patients with T2DM, recruited through convenience sampling. Data were collected from the two healthcare facilities in Dammam, Saudi Arabia, between March and June 2020. Statistical analyses, including independent sample t-tests, one-way ANOVA, and multiple linear regression, were conducted using Statistical Package for the Social Sciences (SPSS) version 26.0.</p><p><strong>Results: </strong>The findings showed that Increased SMC levels were associated with improved clinical outcomes, particularly lower HbA1c levels (p < 0.01). Additionally, SMC was positively associated with psychosocial outcomes (ie, quality of life and mental health; p < 0.05). In contrast, SDM was significantly associated with psychosocial outcomes (p < 0.05), its relationship with HbA1c was non-significant (p= 0.300), indicating only a minor explanatory effect. Additionally, demographic and clinical factors such as sex and lipid levels were found to influence glycemic outcomes, with males and patients with better lipid profiles showing lower HbA1c levels.</p><p><strong>Conclusion: </strong>This study reinforces the pivotal role of SMC in achieving optimal glycemic control and improving the overall well-being of T2DM patients. While shared decision-making (SDM) enhances patient-reported outcomes, its impact on clinical outcomes such as HbA1c was not statistically significant. These findings support patient-centered approaches and highlight the need for further longitudinal research to confirm causal relationships. The results highlight the value of integrating comprehensive self-management support and patient-centered decision-making in diabetes care to optimize both clinical and psychosocial outcomes for patients.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2295-2307"},"PeriodicalIF":2.0,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Decision-Making Experience of Self-Management Behaviors in Home Peritoneal Dialysis for Patients with Diabetic Nephropathy: A Qualitative Study Using the Theory of Planned Behavior.","authors":"Zihao Song, Yuping Xiao, Yanjin Su, Gangxin Qin, Jinxin Yang","doi":"10.2147/PPA.S537890","DOIUrl":"10.2147/PPA.S537890","url":null,"abstract":"<p><strong>Purpose: </strong>Self-management among diabetic kidney disease(DKD) patients receiving home peritoneal dialysis(PD) remains a significant challenge, warranting further exploration. In this study, the Theory of Planned Behavior (TPB) was used to clarify patients' decision-making processes and understand the reasons for adhering to and changing behaviors.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 16 DKD patients who were undergoing follow-up and receiving home PD. The TPB was applied to formulate the interview themes and provide information for the Interpretative Phenomenological Analysis (IPA) method used.</p><p><strong>Results: </strong>A total of 3 themes and 7 sub-themes were summarized, namely attitude towards behavior, where physical and mental perception affects the decision-making attitude (the positive feedback of improved physical function strengthens the decision-making attitude; the two-way influence of emotions catalyzes the decision-making attitude); subjective norm, where social factors drive the decision-making belief (the behavioral outcomes of peers transform the decision-making belief; the continuity of medical and nursing services consolidates the decision-making belief; the motivation of social feedback stimulates the decision-making belief); perceived behavioral control, where self-perception influences the decision-making intention (positive self-efficacy motivates the decision-making intention; the limitation of external resources restricts the decision-making intention).</p><p><strong>Conclusion: </strong>For the management of home PD in patients with DKD, efforts can be made to improve patients' decision-making in self-management of home PD by strengthening the positive feedback of psychological experiences in behavioral decision-making, exploring digital peer support platforms and social support networks for such patients to improve the mechanism of patients' active participation in decision-making within social support networks, and improving the community support system from multiple dimensions such as incorporating relevant policies into assessment criteria, coordinating funds through multiple channels, enhancing the capabilities of community medical and nursing teams, and encouraging doctor-patient shared decision-making, thereby exploring and constructing a community assistance model for the management of home PD in patients with DKD.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2283-2294"},"PeriodicalIF":2.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generative AI/LLMs for Plain Language Medical Information for Patients, Caregivers and General Public: Opportunities, Risks and Ethics.","authors":"Avishek Pal, Tenzin Wangmo, Trishna Bharadia, Mithi Ahmed-Richards, Mayank Bhailalbhai Bhanderi, Rohitbhai Kachhadiya, Samuel S Allemann, Bernice Simone Elger","doi":"10.2147/PPA.S527922","DOIUrl":"10.2147/PPA.S527922","url":null,"abstract":"<p><p>Generative artificial intelligence (gAI) tools and large language models (LLMs) are gaining popularity among non-specialist audiences (patients, caregivers, and the general public) as a source of plain language medical information. AI-based models have the potential to act as a convenient, customizable and easy-to-access source of information that can improve patients' self-care and health literacy and enable greater engagement with clinicians. However, serious negative outcomes could occur if these tools fail to provide reliable, relevant and understandable medical information. Herein, we review published findings on opportunities and risks associated with such use of gAI/LLMs. We reviewed 44 articles published between January 2023 and July 2024. From the included articles, we find a focus on readability and accuracy; however, only three studies involved actual patients. Responses were reported to be reasonably accurate and sufficiently readable and detailed. The most commonly reported risks were oversimplification, over-generalization, lower accuracy in response to complex questions, and lack of transparency regarding information sources. There are ethical concerns that overreliance/unsupervised reliance on gAI/LLMs could lead to the \"humanizing\" of these models and pose a risk to patient health equity, inclusiveness and data privacy. For these technologies to be truly transformative, they must become more transparent, have appropriate governance and monitoring, and incorporate feedback from healthcare professionals (HCPs), patients, and other experts. Uptake of these technologies will also need education and awareness among non-specialist audiences around their optimal use as sources of plain language medical information.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2227-2249"},"PeriodicalIF":2.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12325106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medication Adherence in Adults with Type 2 Diabetes: A Comprehensive Qualitative Meta-Synthesis of Factors in the MENA Region.","authors":"Nasser Al-Salmi, Joshua K Muliira, Eilean Rathinasamy Lazarus","doi":"10.2147/PPA.S526844","DOIUrl":"10.2147/PPA.S526844","url":null,"abstract":"<p><strong>Purpose: </strong>Medication adherence is a critical factor in the management of Type 2 Diabetes (T2D) and plays a vital role in slowing disease progression, preventing complications and improving health outcomes. This study fills this gap by systematically integrating findings from qualitative studies to provide a comprehensive understanding of the multilevel determinants of adherence unique to the MENA sociocultural context.</p><p><strong>Methods: </strong>A metasynthesis was conducted using a thematic synthesis approach, incorporating data from nine qualitative studies. The search was limited to research articles published in English between 2014 and 2024.</p><p><strong>Results: </strong>The metasynthesis identified four key themes: (1) personal factors and perceptions related to the disease and medications are fundamental to adherence, (2) healthcare provider attitudes and practices can improve adherence to medications, (3) the healthcare system is a key factor for optimal adherence, and (4) sociocultural, alternative medicine, and religious practices affect adherence in the MENA region.</p><p><strong>Conclusion: </strong>Medication adherence among adults with T2D in the MENA region is influenced by factors related to the individual patients, healthcare providers, healthcare system, and sociocultural practices. There is a need for more qualitative studies to address existing knowledge gaps about the agency of the above factors in regard to initiation and control of actions that lead to medication adherence.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2263-2281"},"PeriodicalIF":2.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Medication Adherence and Lifestyle Changes: An Image-Based Educational Tool for Patients with Heart Failure.","authors":"Lingyan Gao, Qing Xie, Tiantian Liu, Hua Liu, Suying Yan, Yalei Han, Meijing Zhang, Dawei Zhu, Na Guo, Stephen Nicholas, Elizabeth Maitland, Dongxiao Wang","doi":"10.2147/PPA.S530695","DOIUrl":"10.2147/PPA.S530695","url":null,"abstract":"<p><strong>Background: </strong>A lack of disease-specific knowledge in heart failure (HF) patients is associated with poor adherence to complex medication regimens and non-pharmacological recommendations, especially among individuals with low health literacy. Existing educational tools have been shown to be inadequate, highlighting the need for more accessible and effective alternatives.</p><p><strong>Purpose: </strong>To develop an educational tool that improves HF knowledge in a more accessible and effective way.</p><p><strong>Methods: </strong>An image-based educational tool was created by healthcare professionals and HF patients, drawing on the Health Belief Model (HBM) and utilizing both qualitative and quantitative approaches. Project objectives were defined and content was guided by a literature review and focus group interviews. The tool was refined through iterative optimization using feedback and questionnaires.</p><p><strong>Results: </strong>Thirteen healthcare professionals and eight HF patients participated in the development and refinement of the educational tool. The final tool consisted of seven A3-sized images and accompanying text, addressing the following topics: (1) Cognition of HF; (2) Cause and classification of HF; (3) Inducing factors and prevention of HF; (4)-(5) Medication treatments of HF; (6) Exercise and self-management of HF; (7) \"We are on the same journey\" - a supportive theme for HF patients. The final version of the tool demonstrated high accuracy, readability, usability, and overall satisfaction, with all categories receiving scores of ≥4.5 on a 5-point Likert scale.</p><p><strong>Conclusion: </strong>The image-based educational tool, developed using HBM, effectively meets the needs of HF patients. It shows strong performance in terms of accuracy, readability, usability, and satisfaction, which may ultimately help improve adherence to both pharmacological treatments and non-pharmacological recommendations for HF management.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2251-2262"},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging Research Trends on Medication Adherence in Tuberculosis Treatment: A Bibliometric Study of Research Between 2015 and 2024 to Inform Future Research Trajectory.","authors":"Sidik Maulana, Lutfian Lutfian, Izdihar Javier Wardika, Rahmat Fadhli, Desfara Anggreani, Jonathan Hasian Haposan, Fahmi Wildana, Melani Adelia Efendi, Hesti Platini, Hartiah Haroen","doi":"10.2147/PPA.S520341","DOIUrl":"10.2147/PPA.S520341","url":null,"abstract":"<p><strong>Introduction: </strong>Current knowledge regarding tuberculosis (TB) medication adherence largely stems from scientific publications. However, to date, the volume and characteristics of studies specifically focused on TB medication adherence in Southeast Asia have not yet been systematically assessed. This study aims to conduct a comprehensive bibliometric analysis of research on medication adherence in TB treatment within this region.</p><p><strong>Methods: </strong>A bibliometric analysis was conducted using the Scopus database to identify research articles related to medication adherence in TB treatment in Southeast Asia, published in English between 2015 and 2024. The analysis included the number of publication trends, country of origin, citation metrics, co-authorship networks, keyword co-occurrence, and the most frequently cited documents.</p><p><strong>Results: </strong>A total of 146 journal articles were retrieved. Indonesia emerged as the most prolific contributor and demonstrated strong international collaboration. Keyword co-occurrence analysis revealed four major research themes: (1) clinical and demographic characteristics, (2) pharmacological management and disease burden, (3) socio-behavioral factors related to adherence, and (4) digital health-based treatment evaluation. Burst analysis of reference and keyword highlighted emerging research trends, particularly in \"primary-community based care\" and \"digital health interventions\", indicating potential trajectories for future research in TB medication adherence.</p><p><strong>Conclusion: </strong>This study provided an overview of the evolving research landscape on TB medication adherence in Southeast Asia. These findings highlight the growing emphasis on primary-community based care and digital health interventions, pointing toward shaping future research and practice.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2213-2226"},"PeriodicalIF":2.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}