Medication Adherence in Adults with Type 2 Diabetes: A Comprehensive Qualitative Meta-Synthesis of Factors in the MENA Region.

IF 2 3区医学 Q2 MEDICINE, GENERAL & INTERNAL

Patient preference and adherence Pub Date : 2025-07-31 eCollection Date: 2025-01-01 DOI:10.2147/PPA.S526844

Nasser Al-Salmi, Joshua K Muliira, Eilean Rathinasamy Lazarus

{"title":"Medication Adherence in Adults with Type 2 Diabetes: A Comprehensive Qualitative Meta-Synthesis of Factors in the MENA Region.","authors":"Nasser Al-Salmi, Joshua K Muliira, Eilean Rathinasamy Lazarus","doi":"10.2147/PPA.S526844","DOIUrl":null,"url":null,"abstract":"Purpose: Medication adherence is a critical factor in the management of Type 2 Diabetes (T2D) and plays a vital role in slowing disease progression, preventing complications and improving health outcomes. This study fills this gap by systematically integrating findings from qualitative studies to provide a comprehensive understanding of the multilevel determinants of adherence unique to the MENA sociocultural context.Methods: A metasynthesis was conducted using a thematic synthesis approach, incorporating data from nine qualitative studies. The search was limited to research articles published in English between 2014 and 2024.Results: The metasynthesis identified four key themes: (1) personal factors and perceptions related to the disease and medications are fundamental to adherence, (2) healthcare provider attitudes and practices can improve adherence to medications, (3) the healthcare system is a key factor for optimal adherence, and (4) sociocultural, alternative medicine, and religious practices affect adherence in the MENA region.Conclusion: Medication adherence among adults with T2D in the MENA region is influenced by factors related to the individual patients, healthcare providers, healthcare system, and sociocultural practices. There is a need for more qualitative studies to address existing knowledge gaps about the agency of the above factors in regard to initiation and control of actions that lead to medication adherence.","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2263-2281"},"PeriodicalIF":2.0000,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323785/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Patient preference and adherence","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/PPA.S526844","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Medication adherence is a critical factor in the management of Type 2 Diabetes (T2D) and plays a vital role in slowing disease progression, preventing complications and improving health outcomes. This study fills this gap by systematically integrating findings from qualitative studies to provide a comprehensive understanding of the multilevel determinants of adherence unique to the MENA sociocultural context.

Methods: A metasynthesis was conducted using a thematic synthesis approach, incorporating data from nine qualitative studies. The search was limited to research articles published in English between 2014 and 2024.

Results: The metasynthesis identified four key themes: (1) personal factors and perceptions related to the disease and medications are fundamental to adherence, (2) healthcare provider attitudes and practices can improve adherence to medications, (3) the healthcare system is a key factor for optimal adherence, and (4) sociocultural, alternative medicine, and religious practices affect adherence in the MENA region.

Conclusion: Medication adherence among adults with T2D in the MENA region is influenced by factors related to the individual patients, healthcare providers, healthcare system, and sociocultural practices. There is a need for more qualitative studies to address existing knowledge gaps about the agency of the above factors in regard to initiation and control of actions that lead to medication adherence.

Abstract Image

查看原文本刊更多论文

成人2型糖尿病患者的药物依从性：中东和北非地区因素的综合定性综合

目的：药物依从性是2型糖尿病（T2D）治疗的关键因素，在减缓疾病进展、预防并发症和改善健康结果方面起着至关重要的作用。本研究通过系统地整合定性研究的结果来填补这一空白，以提供对中东和北非社会文化背景下独特的依从性的多层次决定因素的全面理解。方法：采用主题综合方法进行综合，纳入了九项定性研究的数据。该搜索仅限于2014年至2024年间用英文发表的研究文章。结果：综合分析确定了四个关键主题：(1)与疾病和药物相关的个人因素和认知是依从性的基础；(2)医疗保健提供者的态度和做法可以提高药物依从性；(3)医疗保健系统是最佳依从性的关键因素；(4)社会文化、替代医学和宗教习俗影响MENA地区的依从性。结论：中东和北非地区成人T2D患者的药物依从性受到患者个体、医疗服务提供者、医疗体系和社会文化习俗等因素的影响。有必要进行更多的定性研究，以解决有关上述因素在导致药物依从性的行动的启动和控制方面的作用的现有知识差距。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Patient preference and adherence MEDICINE, GENERAL & INTERNAL-

CiteScore

3.60

自引率

4.50%

发文量

354

审稿时长

6-12 weeks

期刊介绍： Patient Preference and Adherence is an international, peer reviewed, open access journal that focuses on the growing importance of patient preference and adherence throughout the therapeutic continuum. The journal is characterized by the rapid reporting of reviews, original research, modeling and clinical studies across all therapeutic areas. Patient satisfaction, acceptability, quality of life, compliance, persistence and their role in developing new therapeutic modalities and compounds to optimize clinical outcomes for existing disease states are major areas of interest for the journal. As of 1st April 2019, Patient Preference and Adherence will no longer consider meta-analyses for publication.