Patient preference and adherence最新文献

{"title":"Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania.","authors":"Gheorghe Gindrovel Dumitra, Ancuța Ramona Camen, Florina Nechita, Mihail Cristian Pîrlog, Constantin Kamal, Carmen Adriana Dogaru, Mirela Radu, Elena Codruța Gheorghe, Elena Madalina Dumitrescu, Venera Cristina Dinescu, Roxana Surugiu, Carmen Nicoleta Oancea, Adina Turcu-Stiolica","doi":"10.2147/PPA.S500640","DOIUrl":"https://doi.org/10.2147/PPA.S500640","url":null,"abstract":"<p><strong>Introduction: </strong>Vaccine hesitancy remains a critical barrier to achieving widespread vaccination, particularly in settings with limited public trust and high exposure to misinformation. This study aims to measure the level of vaccine hesitancy, identifying the factors contributing to it, and to evaluate the effectiveness of two targeted interventions-group and individual counseling-designed to address vaccine hesitancy among employees in seven industrial companies in Romania during the Coronavirus disease 2019 (COVID-19) pandemics.</p><p><strong>Methods: </strong>A total of 256 participants were included in the study, and interventions were delivered by family physicians and occupational medicine specialists trained in motivational interviewing (MI) techniques. Data on sociodemographic factors, vaccine hesitancy, and willingness to vaccinate were collected using a questionnaire and a Visual Analogue Scale (VAS) for vaccine willingness.</p><p><strong>Results: </strong>Both interventions led to significant increases in willingness to vaccinate, with group counseling showing a 1.4-point increase on the VAS (p-value < 0.0001) and individual counseling showing a 1.5-point increase (p-value < 0.0001), though the differences between the two approaches were not statistically significant (p-value = 0.209). Key factors correlated with higher levels of vaccine hesitancy included younger age, lower education levels, marital status (single or divorced), having children, the presence of chronic diseases, a lack of general antivaccine beliefs, and a lack of trust in the natural origin of the novel coronavirus (SARS-CoV-2).</p><p><strong>Conclusion: </strong>This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing hesitancy included demographic characteristics (age, marital status) and social determinants (education level, anti-vaccine beliefs, parenthood, and chronic illness). The findings emphasize the role of trusted healthcare professionals in addressing these concerns through targeted communication strategies, such as motivational interviewing.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"907-919"},"PeriodicalIF":2.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normoglycemia and Weight Reduction: Perspectives of People with Type 2 Diabetes in Australia.","authors":"Rachel S Newson, Helen Barraclough, Jennifer Lapthorn, Martin Stewart, Sam Colman, Michael D'Emden","doi":"10.2147/PPA.S503673","DOIUrl":"https://doi.org/10.2147/PPA.S503673","url":null,"abstract":"<p><strong>Purpose: </strong>As more treatments become available to normalize glycated hemoglobin (HbA1c) levels and reduce weight, it is important to understand the meaningfulness of achieving target HbA1c levels and weight reduction from the perspective of people with type 2 diabetes.</p><p><strong>Patients and methods: </strong>This is a cross-sectional survey of 300 Australians with type 2 diabetes.</p><p><strong>Results: </strong>Achieving target HbA1c levels was meaningful to 90.0% (n=198) and moderately/very/extremely important to 94.5% (n=208) of the 220 participants with HbA1c >6.0%. Over half of the participants were dissatisfied with their current weight (n=158, 52.7%) and underreported their body mass index category (n=160, 53.3%). For 59.0% (n=177), a mean (±standard deviation) of 17.2 (±20.6) kg of weight loss was meaningful. Of these participants, 10.7%, 30.5%, 21.5%, and 37.3% viewed 5%, 5-10%, 10%-15%, and >15% of weight reduction as meaningful, respectively.</p><p><strong>Conclusion: </strong>According to this survey, achieving target HbA1c levels is both meaningful and important to most people with type 2 diabetes. Achieving weight reduction is also seen as important despite frequent underrating of body mass index. Therapies targeting both target HbA1c levels and weight reduction may be of interest to people with type 2 diabetes in Australia, and this could impact medication adherence and health outcomes.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"897-905"},"PeriodicalIF":2.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who is Seeking Traditional Chinese Medicine (TCM) for Cancer? Insights from a Large Cohort in a Rehabilitation Clinic.","authors":"Yong Zhang, Yiding Dai, Dan Kang, Qingsong Yu, Xiangxi Zhou, Xin Tian, Qiulong Chen, Yi Chen, Fang Liu, Qiuling Shi","doi":"10.2147/PPA.S509263","DOIUrl":"10.2147/PPA.S509263","url":null,"abstract":"<p><strong>Purpose: </strong>Traditional Chinese Medicine (TCM) is widely used in cancer care, yet its utilization features are not well understood. By providing a comprehensive overview of the demographic and clinical characteristics, symptom burden, HRQoL, and TCM constitution of cancer patients seeking TCM treatment, we aim to offer insights into the integration of TCM into cancer care.</p><p><strong>Patients and methods: </strong>The questionnaire collected data on demographic and clinical characteristics, the MD Anderson Symptom Inventory for Traditional Chinese Medicine (MDASI-TCM), the EuroQol-5Dimensions-5Levels (EQ-5D-5L), and the simplified version of the Constitution in Chinese Medicine Questionnaire (CCMQ). A descriptive analysis was conducted to profile the patients' status and expectations of TCM. Chi-square or Fisher exact tests were employed to compare the distribution of TCM constitutional types across different cancer diagnoses.</p><p><strong>Results: </strong>Among 3047 eligible patients, 2796 (median age 55) completed the questionnaire and were subsequently included in the analysis. The cohort was predominantly female (56.5%), with lung cancer being the most common primary diagnosis (25.2%). Furthermore, 86.7% of the patients presented with a good performance status (ECOG-PS ≤ 1). The main reasons patients sought TCM treatment were to alleviate cancer-related symptoms (59.4%) and enhance immune function (55.4%). The most prevalent symptoms (scored 1-10 on a 0-10 scale) were fatigue (81.1%), followed by disturbed sleep (81.0%), and dry mouth (78.2%). The mean and median EQ-5D-5L utility scores were 0.81 and 0.89, respectively. About 83.4% of cancer patients exhibited a deviation in TCM constitution, with Yang-deficiency being particularly common among them.</p><p><strong>Conclusion: </strong>This study highlights the symptom burden, HRQoL, TCM constitution, and characteristics of patients who pursue TCM treatment. It advances our understanding of TCM's role in cancer rehabilitation by shedding light on target population potential needs of care. The findings provide a foundation for developing evidence-based strategies to enhance TCM application in clinical settings, optimize resource allocation, and improve rehabilitation outcomes for cancer patients.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"883-896"},"PeriodicalIF":2.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11972600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Empirical Comparison of Discrete Choice Experiment and Best-Worst Scaling to Estimate Patient Preferences in Infertility Treatment in China.","authors":"Jiali Chen, Xiaodan Qian, Dan Su, Jinhong Gong, Jingjing Shang, Lingli Zhang, Xin Li","doi":"10.2147/PPA.S501723","DOIUrl":"10.2147/PPA.S501723","url":null,"abstract":"<p><strong>Background: </strong>Infertility has become a growing public health problem in China. It is important to accurately and easily obtain patient preferences. This study aimed to obtain and compare stated preference results from the perspective of infertility patients. By assessing the validity and acceptability of both methods, it provides lessons for empirical research and practical application.</p><p><strong>Methods: </strong>Discrete choice experiments (DCE) and profile case best-worst scaling (BWS-2) are methods used to identify and weigh various criteria affecting the order of priorities. We conducted a face-to-face survey of female patients with infertility aged between 20-45 years. The survey included socio-demographic information, preference questionnaires and completion of evaluation questions. Attributes included live birth rate, pregnancy rate, degree of participation in treatment decision making, maternal complications, neonatal complications and program cost. Conditional logit models were used to analyze attribute level weights and relative importance was calculated separately.</p><p><strong>Results: </strong>A total of 330 valid questionnaires were collected. The preferences of patients experiencing infertility were quantified through two stated preference research methods. The findings indicated that patients exhibited a preference for treatment options that were highly effective, exhibited minimal side effects, were patient-centered, and were cost-effective. The BWS-2 and DCE preference weights demonstrated high consistency, with only slight difference observed in the ranking of individual attributes within the order of relative importance. In the view of the patients, the DCE questions were perceived to be less challenging to comprehend and were therefore preferred to be completed.</p><p><strong>Conclusion: </strong>The BWS-2 and DCE exhibit identical validity and highly consistent preference results. In the context of specific research questions, the selection of a method or the combination of methods must be suitable to the purpose of the study in order to ensure that the utility gained is maximized. Further research is required to corroborate these findings.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"869-882"},"PeriodicalIF":2.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Preferences for Episodic Migraine Medications: A Discrete Choice Experiment of Self-Injectable Versus Oral Treatments Targeting Calcitonin Gene-Related Peptide Pathway.","authors":"Chiara Whichello, Lars Viktrup, Oralee J Varnado, Matthew Quaife, Myrto Trapali, Antje Tockhorn-Heidenreich","doi":"10.2147/PPA.S496736","DOIUrl":"10.2147/PPA.S496736","url":null,"abstract":"<p><strong>Purpose: </strong>To understand the trade-offs that patients with episodic migraine are willing to make between attributes of self-injectable calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) and oral small-molecule calcitonin gene-related peptide receptor antagonists (gepants).</p><p><strong>Patients and methods: </strong>This was an online discrete choice experiment survey among adults with episodic migraine (≥4 and <15 migraine headache days and <15 headache days per month over 3 months) in the United States. Hypothetical treatments were characterized by five attributes: chance of ≥50% migraine reduction, impact on daily activities, onset of treatment effect, reduction in number of acute medications, and treatment administration. The attributes were selected based on insights gained from a previously conducted literature review and focus group study and aligned with the primary and secondary outcome measures in the double-blind Phase IV head-to-head clinical trial of a CGRP mAb versus gepant.</p><p><strong>Results: </strong>601 patients (mean age: 44.8 years) completed the survey. Treatment preferences differed significantly between patients. However, for all patients, the most important driver of treatment preferences was the chance of a ≥50% reduction in monthly migraine headache days (relative attribute importance: 38.3%), followed by the impact on daily activities (23.5%), the onset of treatment effect (19.5%), the reduction in need for acute medication (15.4%), and finally the route of administration (3.4%). Patients were willing to consider a one-week delayed onset of treatment effect or one-day increased need for acute medication for a higher chance (by 2.06% and 2.65% respectively) of a ≥50% reduction in monthly migraine headache days. Patients would trade a reduction of migraine's impact on daily activities from \"extreme\" to \"moderate\" or \"minimal\" with a lower chance (17.09%, 12.06% respectively) of halving the number of monthly migraine headache days.</p><p><strong>Conclusion: </strong>A ≥50% reduction in monthly migraine headache days was the most important treatment attribute for which participants were willing to trade against other attributes. The variation in treatment preferences between patients emphasizes the importance to align decision-making with individual patients' preferences.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"839-853"},"PeriodicalIF":2.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colonoscopy Uptake in First-Degree Relatives of CRC Patients: Challenges and Intervention Strategies.","authors":"Weihua Liu, Mindi Liu, Ping Li, YingHui Hou, Qing Zhao, Limei Xing, Ying Wang, Cong Fu","doi":"10.2147/PPA.S501332","DOIUrl":"10.2147/PPA.S501332","url":null,"abstract":"<p><strong>Objective: </strong>Colorectal cancer (CRC) screening is crucial for early detection and prevention. However, the willingness of first-degree relatives of CRC patients to undergo colonoscopy often remains low, impacting early diagnosis and treatment outcomes.</p><p><strong>Methods: </strong>This article reviewed the relevant concepts, research status, evaluation methods, influencing factors and intervention measures of first-degree relatives of patients with colorectal cancer.</p><p><strong>Results: </strong>Through the review, it is found that there is still a large gap in the research on the development of assessment tools and intervention programs. Existing intervention programs often fail to address the unique demographic, cognitive, psychological, family dynamic, and social barriers faced by this population. Future research should prioritize the development of specific assessment tools that can accurately measure the willingness of first-degree relatives to undergo colonoscopy, taking into account cultural nuances and contextual factors. By addressing psychological and social factors, researchers can develop more targeted and effective programs that enhance understanding and motivation for colonoscopy screening.</p><p><strong>Conclusion: </strong>This study provides references for domestic research on the willingness of first-degree relatives for colonoscopy, provide new ideas for formulating intervention methods more suitable for first-degree relatives for colonoscopy, and promote their willingness to perform colonoscopy.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"855-868"},"PeriodicalIF":2.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preferences for First-Line Chronic Lymphocytic Leukemia Treatments: Results From a Multinational Study on the Perspectives of Patients and Physicians.","authors":"Bersabeh Sile, Dipen Patel, Dahbia Horchi, Bleuenn Rault, Emily Mulvihill, Kathleen Beusterien, Katherine Stewart, Paulo Miranda, Xavier Guillaume","doi":"10.2147/PPA.S510401","DOIUrl":"10.2147/PPA.S510401","url":null,"abstract":"<p><strong>Background: </strong>Few studies have explored physician and patient preferences for the treatment of chronic lymphocytic leukemia (CLL) related to treatment efficacy, adverse events (AEs), and treatment duration. Thus, this observational, mixed-methods study investigated patients' and physicians' preferences for CLL first-line treatments.</p><p><strong>Materials and methods: </strong>An online discrete choice experiment in five countries among 192 patients and 259 physicians in the US, the UK, Germany, France, and Australia examined the importance of outcomes and treatment attributes.</p><p><strong>Results: </strong>Increasing 5-year progression-free survival (5-year PFS) was most important to patients and physicians, with a relative importance (RI) of 30.3% among patients and 37.8% among physicians, followed by reducing the risks of common side effects (RI 21.6% among patients, 22.9% among physicians) and adverse events (AEs) leading to treatment discontinuation (RI 22.1% among patients, 20.6% among physicians). Patients strongly preferred time limited treatment regimen over treatment to progression (TTP). Specifically, patients and physicians would require a 6.4% vs 2.3% increase in 5-year PFS, a 19.4% vs 8.9% decrease in the risk of common all grades side effects, and a 7.5% vs 3.7% decrease in the risk of treatment discontinuation due to AEs, respectively, to compensate for a daily oral medication taken indefinitely vs daily oral medication taken for 24 months.</p><p><strong>Conclusion: </strong>Overall, patients and physicians favor time-limited treatment regimens over TTP and value treatments with greater PFS benefits followed by lower side effects. Patients and physicians were both willing to trade-off switching from time-limited treatment to TTP for a better 5-year PFS, decrease side effects, and risk of treatment discontinuation due to AEs.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"823-837"},"PeriodicalIF":2.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Glucose Management Protection Motivation Trajectory and Its Associated Factors in Pregnant Women with Gestational Diabetes Mellitus: A Longitudinal Study.","authors":"Yi Gao, Jun Liu, Qingxian Zhu, Zhiyi Zhang, Qi Dai, Yifan Guo, Wei Zhang, Minjie Jia","doi":"10.2147/PPA.S501614","DOIUrl":"10.2147/PPA.S501614","url":null,"abstract":"<p><strong>Purpose: </strong>To (1) explore the trajectories of blood glucose management protection motivation in pregnant women with gestational diabetes mellitus, based on a growth mixture model, and (2) identify factors associated with these trajectories.</p><p><strong>Patients and methods: </strong>This longitudinal study, conducted between December 2023 and June 2024 at a tertiary hospital in China, involved 313 pregnant women diagnosed with gestational diabetes mellitus who were not using medication to control their blood glucose levels. Participants were assessed at three time points: 24-28 gestational weeks, 29-35 gestational weeks, and 36-40 gestational weeks. The data collected included general demographic information and the level of blood glucose management protection motivation. A growth mixture model was employed to examine the trajectory of blood glucose management protection motivation, and binary logistic regression analysis was performed to identify predictors of the trajectory. This study was reported following the Reporting Observational Longitudinal Research statement.</p><p><strong>Results: </strong>The study identified two distinct trajectories of blood glucose management protection motivation: a low-motivation group (slowly increasing then rapidly declining; 124, 39.62%) and a high-motivation group (rapidly then increasing slowly declining; 189, 60.38%). The independent predictors of these trajectory categories included age, per capita monthly household income, and pregnancy complications.</p><p><strong>Conclusion: </strong>Significant heterogeneity existed in the developmental trajectories of blood glucose management protection motivation among pregnant women with gestational diabetes mellitus. Future research should prioritize developing targeted interventions that consider not only different developmental trajectories but also factors such as age, per capita monthly household income, and pregnancy complications. These strategies may foster blood glucose management protection motivation among pregnant women with gestational diabetes mellitus, addressing their specific needs and enhancing the effectiveness of care.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"809-821"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11960459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: The Concizumab Pen-Injector is Easy to Use and Preferred by Hemophilia Patients and Caregivers: A Usability Study Assessing Pen-Injector Handling and Preference [Corrigendum].","authors":"","doi":"10.2147/PPA.S529186","DOIUrl":"https://doi.org/10.2147/PPA.S529186","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.2147/PPA.S470091.].</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"805-807"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11960467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Talking About Barriers to Disease-Modifying Anti-Rheumatic Drugs: Content Analysis of Audio-Recorded Routine Clinical Visits of Patients with Rheumatoid Arthritis.","authors":"Marieke J H Voshaar, Bart J F Van den Bemt, Mart A van de Laar, Sandra van Dulmen, Johanna E Vriezekolk","doi":"10.2147/PPA.S503083","DOIUrl":"10.2147/PPA.S503083","url":null,"abstract":"<p><strong>Purpose: </strong>Effective healthcare professional-patient communication is essential for medication adherence. Conversations about patient's barriers to medication use, for example, could help to enhance adherence and consequently improve treatment outcomes. However, it is unclear whether and how barriers to medication use are discussed during routine rheumatology consultations. The aims of this study were to examine 1) the barriers and facilitators to medication use raised by patients during real-life rheumatology outpatient consultations, and whether the issue of medication (non)adherence was discussed (communication content); and 2) how rheumatologists responded to the barriers (communication process).</p><p><strong>Methods: </strong>A total of 134 audio-recordings of real-life outpatient rheumatology consultations were analysed. Barriers and facilitators for the current use of disease-modifying anti-rheumatic drugs were identified and categorized using a previously adapted Theoretical Domains Framework. The way rheumatologists responded to the barriers brought up by the patients was analysed using relevant parts of the Roter Interaction Analysis System.</p><p><strong>Results: </strong>In 58 of the 134 consultations, at least one barrier or facilitator to current medication use was brought up by the patient; in 31 out of 134 consultations, medication (non)adherence was addressed. Most facilitators were related to the quality of the needles, the use of an injection pen instead of a syringe, dose reduction because of low disease activity and timing of the medication. The majority of barriers were related to experiencing side effects and doubts about efficacy and resistance of (long-term use of) medication. Rheumatologists' responses to barriers related to disease-modifying anti-rheumatic drugs were mostly a combination of instrumental (counselling) and affective (agreement) communication.</p><p><strong>Conclusion: </strong>Barriers to current disease-modifying anti-rheumatic drugs' use raised by patients and discussed during routine rheumatology consultations were primarily related to side effects and concerns about the efficacy and long-term use. Continuous attention of these barriers and tailored responses to patients' concerns are key to promote better adherence to treatment.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"777-790"},"PeriodicalIF":2.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}