Patient preference and adherence最新文献

{"title":"Developing a Structured Framework for Pharmacist-Led Prescription Medication Counselling: A Scoping Review Integrating Structural Domains and Patient-Centered Operational Features.","authors":"Sunmin Lee, Eonji Han, Yeonwoo Jung","doi":"10.2147/PPA.S605582","DOIUrl":"https://doi.org/10.2147/PPA.S605582","url":null,"abstract":"<p><p>Medication counselling is a core element of pharmaceutical care that supports safe, rational, and adherent medication use. However, despite its importance, medication counselling remains suboptimally implemented in routine practice. A clearer description of how counselling is structured in practice is therefore required. This study aimed not only to map existing practices but to develop a structured framework for pharmacist-led prescription medication counselling by integrating procedural components with patient-centered operational behaviors. The review followed the PRISMA Extension for Scoping Reviews checklist. MEDLINE, Embase, the Cochrane Library, and grey literature were searched for publications from January 2015 to January 2025. Fourteen sources, including both regulatory guidance documents and empirical studies, met the inclusion criteria. Using an adapted TIDieR framework, intervention components were deductively extracted and analyzed. Subsequently, content analysis was conducted to inductively synthesize them into structural domains and patient-centered operational features. Six structural domains were identified: patient identification and encounter framing; risk screening; information provision; understanding verification and engagement; adherence and self-management support; and documentation and referral or escalation. Four patient-centered operational features were also identified: patient context elicitation and prioritization; tailored communication adaptation; interactive understanding verification; and adherence support practices. Structural detail varied across sources, particularly for documentation and adherence-related elements.These operational features function as implementation-level elements within structural domains, linking procedural structure to observable patient-centered behaviors. This integrated framework conceptualizes medication counselling as an operationalized service and provides a foundation for its standardization, implementation, and evaluation in real-world practice.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"605582"},"PeriodicalIF":2.0,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Person-Centered Approaches for Identifying Subgroups of Post-Stroke Depression: A Systematic Review of Observational Studies.","authors":"Dan Shi, Min Zhou, Li Zou","doi":"10.2147/PPA.S598428","DOIUrl":"https://doi.org/10.2147/PPA.S598428","url":null,"abstract":"<p><strong>Background: </strong>Current management for post-stroke depression (PSD) mainly relies on the severity of depression, insufficiently capturing PSD's clinical heterogeneity. No previous systematic review has jointly synthesized cross-sectional and longitudinal observational studies using person-centered approaches to identify PSD subgroups. This systematic review synthesizes evidence from these studies employing person-centered approaches to characterize PSD subgroups.</p><p><strong>Methods: </strong>Comprehensive searches were conducted in nine databases from the inception to September 2025. Observational studies using person-centered approaches to subgroup PSD were included. Two reviewers independently performed data extraction and study quality assessment using the National Institutes of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies.</p><p><strong>Results: </strong>Eleven articles (9 unique cohorts; N = 6729) were included. Cross-sectional studies (4 studies; N = 1400) identified four symptom-based subgroups: low depressive symptoms (46.6%), emotional depressive symptoms (9.4%), atypical depressive symptoms (23.2%), and widespread depressive symptoms (20.8%). Longitudinal studies (5 studies; N = 5329) revealed four trajectory-based subgroups: low and stable/decreasing (59.7%), low but increasing (17.8%), high and stable/increasing (13.6%), and initially high/moderate but declining (8.9%). Latent transition analysis (2 studies; N = 886) showed greater subgroup fluidity within 6-month post-stroke, followed by increasing stability. Predictors of more severe/persistent subgroups included social-demographic, clinical and physiological factors. One study found that all non-low-stable trajectories were associated with significantly increased 10-year mortality (hazard ratios: 1.38-2.62).</p><p><strong>Conclusion: </strong>Person-centered approaches can effectively delineate latent subgroups of PSD characterized by distinct symptom manifestations and trajectories. Findings of this review support a shift away from one-size-fits-all, total-score-based management toward a more nuanced, symptom- and trajectory-informed framework for PSD.</p><p><strong>Systematic review registration: </strong>CRD420251273568.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"598428"},"PeriodicalIF":2.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching Patients to Self-Care for Active, Recurrent Periodontal or Peri-Implant Pockets Guided by the TIME Wound-Healing Model: A Pilot Feasibility Study Based on Clinical and Microbiological Outcomes.","authors":"Jaume Miranda-Rius, Gerard Àlvarez, Vanessa Blanc, Rubén León, Albert Ramírez-Rámiz, Lluís Brunet-Llobet","doi":"10.2147/PPA.S596403","DOIUrl":"https://doi.org/10.2147/PPA.S596403","url":null,"abstract":"<p><strong>Background: </strong>The TIME therapeutic model is used for the management of chronic wounds: Tissue (non-viable); Infection/Inflammation; Moisture (imbalance); Edges (non-advancing). These four components will determine the persistence or the healing of any chronic ulcer on the skin's surface and, by analogy, also those of the ulcerated epithelium at the subgingival level. We aimed to evaluate the clinical and microbiological changes recorded after implementation of this personalized subgingival model.</p><p><strong>Methods: </strong>Twelve patients with active periodontal or peri-implant pockets were recruited for a feasibility study. Patients were instructed to deeply clean these lesions subgingivally using an angulated interdental brush in a vertical position, twice per day for 15 days. On the first and last days, Löe & Silness gingival index and bleeding on probing (BoP) were recorded and samples were collected using the brush head for the quantitative PCR analysis of 8 bacterial species (commensal and pathogenic).</p><p><strong>Results: </strong>Severe gingival inflammation with profuse bleeding was present at baseline in ten patients. Eight of them complied and adhered with 100% of the treatment. Following self-treatment at home, ten patients exhibited normal or mildly inflamed gums. Seven patients no longer had bleeding, four had slight bleeding and only one moderate bleeding. Microbiologically, the total bacterial load significantly decreased from 7E07 to 9.39E06 cfu/head.</p><p><strong>Conclusion: </strong>This proposed conservative cost-effective subgingival model could significantly improve the inflammatory activity of certain recurrent periodontal or peri-implant pockets, stabilize them and thus minimize their progression. The preliminary findings reflected a reduction or absence of bleeding, a relative decrease in pathogenic species, and the restoration of a microbial community in symbiosis with the host.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"596403"},"PeriodicalIF":2.0,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"iPREFER: Patients' Experiences and Preference of Treatment for Multiple Myeloma Following Multiple Lines of Treatment - A Qualitative Study.","authors":"Melissa Betty Perry, Ramsay Lochhead Devaraj, Kate Law, Fay Ashby, Sally Taylor","doi":"10.2147/PPA.S576524","DOIUrl":"https://doi.org/10.2147/PPA.S576524","url":null,"abstract":"<p><strong>Purpose: </strong>Each year in the United Kingdom, approximately 6000 people are diagnosed with Multiple Myeloma (MM) and treated with targeted cancer drugs. The duration and frequency of these treatments vary and include oral, intravenous (IV), and subcutaneous administration. Patients often undergo multiple lines of treatment and live with uncertainty spanning years and decades. This study (ClinicalTrials.gov Identifier: NCT06322927) explores the experiences of people receiving treatment for MM, what matters most when making treatment decisions, and what influences their treatment preference.</p><p><strong>Patients and methods: </strong>This was a qualitative study using semi-structured interviews. Patients were eligible if they had a confirmed MM diagnosis and received at least five lines of treatment. Interviews focused on their extensive experiences of multiple lines of oral anti-cancer and bispecific antibody treatment, or IV therapy, and were analyzed using inductive thematic analysis.</p><p><strong>Results: </strong>Four key themes were identified from nine interviews: \"Living with MM and its impact on quality of life\", portrays the relentless challenges and side effects of MM; \"Factors influencing treatment decision making\" outlines the importance of family, shared decision-making and information needs; \"Factors influencing treatment experience\", including practical challenges, and self-management; and \"Treatment preference\" explores participants' perceptions of treatment within the context of their own circumstances. Participants showed a willingness and tolerance to accept treatments that significantly impact their everyday life, quality of life, and relationships, to achieve their goals of care.</p><p><strong>Conclusion: </strong>The findings highlight the need for healthcare professionals to better understand individual patient circumstances and priorities, inform them of the treatment impact on their priorities to empower patients to choose the right treatment for them and improve quality of life. More research is needed to understand how to integrate this into the clinical care pathway.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"576524"},"PeriodicalIF":2.0,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intertemporal Decision-Making Ability in Patients with Chronic Diseases: A Concept Analysis.","authors":"Xingru Li, Youmin Lu, Wenguang Xie, Wenhao Zhang, Chao Zhang, Tiantian Zhou","doi":"10.2147/PPA.S604005","DOIUrl":"https://doi.org/10.2147/PPA.S604005","url":null,"abstract":"<p><strong>Purpose: </strong>Intertemporal decision-making ability influences adherence to health behavior and clinical outcomes in patients with chronic diseases. However, its concept remains insufficiently defined. This study aimed to identify the key attributes, antecedents, consequences, and empirical referents of intertemporal decision-making ability in patients with chronic diseases.</p><p><strong>Methods: </strong>The Walker and Avant's concept analysis method was used. A systematic search for studies on intertemporal decision-making ability in patients with chronic diseases was conducted across the following databases: PubMed, Web of Science, CINAHL, Embase, PsycINFO, and the China National Knowledge Infrastructure (CNKI). The search covered literature from the beginning until January 2026.</p><p><strong>Results: </strong>A total of 35 articles were included. Four defining attributes of intertemporal decision-making ability in patients with chronic diseases were identified: impulse control, emotional self-regulation, future health valuation, and future-oriented thinking and planning. Antecedents included economic factors, knowledge level, perceived health competence, disease status, emotional status, personality traits, and time perspective, while its consequences encompassed improved psychological status, adherence, and clinical outcomes.</p><p><strong>Conclusion: </strong>Intertemporal decision-making ability in patients with chronic diseases is a multidimensional psychological construct. A thorough examination of this concept can facilitate the development of appropriate assessment instruments and stratified interventions. In clinical practice, healthcare providers can deliver individualized interventions based on patients' specific deficient attributes, using strategies such as immediate rewards, environmental restructuring, health education, and episodic future thinking training to enhance intertemporal decision-making ability, thereby improving adherence to health behaviors and optimizing clinical outcomes.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"604005"},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13134571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Medication Non-Adherence in 1,750 Indonesian Adults with Chronic Diseases: A Nationwide Cross-Sectional Study.","authors":"Sofa D Alfian, Meliana Griselda, Indah L Hilmi, Abdullah A Alshehri, Irma M Puspitasari, Rizky Abdulah","doi":"10.2147/PPA.S599598","DOIUrl":"https://doi.org/10.2147/PPA.S599598","url":null,"abstract":"<p><strong>Purpose: </strong>Medication adherence is critical for effective chronic disease management, yet non-adherence remains a major challenge. Current evidence on medication adherence in Indonesia is constrained by small sample sizes, narrow geographic scope, and a failure to adequately account for the complex interplay of social, economic, and cultural factors. This study aimed to identify factors associated with medication non-adherence in patients with chronic diseases in Indonesia.</p><p><strong>Methods: </strong>This nationwide cross-sectional study was carried out across 34 provinces in Indonesia during April - November 2024. Participants were patients aged 20-74 years diagnosed with at least one chronic disease. Medication non-adherence was assessed through an online and offline self-reported survey. Data was analyzed using multivariable logistic regression, with Odds Ratio (OR) and 95% Confidence Interval (CI) reported.</p><p><strong>Results: </strong>Among 1,750 participants, 957 (54.7%) were adherent and 793 (45.3%) were non-adherent. Non-adherence was most prevalent in digestive diseases (371/541; 68.6%) and psychiatric disorders (37/52; 71.2%). In multivariable logistic regression, younger age (20-30 years: aOR 4.53, 95% CI 2.90-7.09), residence in Java and Bali (aOR 3.21, 95% CI 1.85-5.56), lower income (<IDR 1,500,000: aOR 2.08, 95% CI 1.48-2.92), absence of health insurance (aOR 1.43, 95% CI 1.06-1.92), self-perceived health status (healthy: aOR 2.48, 95% CI 1.63-3.77), and healthcare-seeking behavior (self-medication: aOR 3.36, 95% CI 2.37-4.77; no treatment: aOR 8.77, 95% CI 4.98-15.44) were significantly associated with non-adherence.</p><p><strong>Conclusion: </strong>Medication non-adherence affected nearly half of Indonesian patients with chronic diseases. Strengthening health insurance coverage, addressing financial and geographic disparities, and implementing targeted education strategies, including gender-sensitive approaches that address financial barriers among women and health perception-related factors among men, are essential to improve medication adherence.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"599598"},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in Perspectives of Weight Management Among People in the US and Canada with Type 2 Diabetes by Body Mass Index.","authors":"Melissa M Ross, Sarah Mulnick, Kristina S Boye, Ashley Samuelson, Vivian Thuyanh Thieu, Christine Longuet, Jennifer Glass, Meredith M Hoog","doi":"10.2147/PPA.S574743","DOIUrl":"https://doi.org/10.2147/PPA.S574743","url":null,"abstract":"<p><strong>Purpose: </strong>The link between type 2 diabetes (T2D) and obesity is well established; guidelines for treating T2D include recommendations to support healthy weight reduction. This study explored the perspectives of people in the US and Canada with T2D across BMI categories regarding the perceived value of reaching a lower weight and how this would impact their lives.</p><p><strong>Patients and methods: </strong>A quantitative cross-sectional survey informed by a targeted literature review and qualitative interviews was administered in English to adults in the US and Canada with T2D. Enrollment ensured a sample representative of the T2D population by BMI (per US census data). The survey explored weight management experience, impacts of T2D and weight on quality of life (QOL), and perceived value of 5%/10%/20% weight reductions. Results were summarized descriptively. Chi-squared tests and <i>t</i>-tests assessed significant differences between BMI categories (p<0.05).</p><p><strong>Results: </strong>The 746 participants had a mean (SD) BMI of 32.8 kg/m² (8.2). Nearly all (93%) felt weight management was important to managing their T2D, regardless of BMI. Most (66%) reported currently thinking about and trying to lose weight at least multiple times each week over the last 2 years, especially those with higher BMIs (p<0.001). Higher BMI was also associated with more impacts of weight on T2D (emotional well-being, medical/health complications, physical/mobility limitations, sleep, daily activities, social and financial). Participants with higher BMIs desired greater weight reduction than those with lower BMIs when defining dream, achievable, acceptable and unsuccessful weight goals and were more likely to expect positive and meaningful impacts on their life with 5%/10%/20% weight reductions.</p><p><strong>Conclusion: </strong>Participants with T2D positively valued weight reduction and anticipate it to lead to improvements in their overall T2D management and QOL. As the percentage of weight reduction increased, those with higher BMIs perceived greater meaningfulness and more positive impacts.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"574743"},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13134561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Patient Satisfaction with TB Care Services in Southern Afghanistan.","authors":"Muhammad Haroon Stanikzai, Hazratullah Bariz, Zabihullah Anwary, Ahmad Haroon Baray, Jawad Shirzad, Omid Dadras","doi":"10.2147/PPA.S602353","DOIUrl":"https://doi.org/10.2147/PPA.S602353","url":null,"abstract":"<p><strong>Background: </strong>Patient satisfaction is an important measure of high-quality TB care. However, no study has investigated patient satisfaction with TB care services in Afghanistan. Therefore, this study aims to assess patient satisfaction with TB care services in Southern Afghanistan.</p><p><strong>Methods: </strong>Between October and December 2025, a cross-sectional study was carried out among adult TB patients, who were randomly selected from six TB care centers in Southern Afghanistan. The outcome variable was patient satisfaction, assessed by the Patient Satisfaction Questionnaire-18 (PSQ-18). Bivariate and multivariable logistic regression models were fitted to identify factors associated with patient dissatisfaction.</p><p><strong>Results: </strong>Of 413 patients, 44.5% (95% CI: 39.6%-49.4%) were dissatisfied. The domains with the lowest satisfaction scores were financial aspects, followed by time spent with doctors. Patients living in rural areas (AOR = 1.72; 95% CI: 1.07-2.77), with lower household income (AOR = 1.73; 95% CI: 1.07-2.79), incurring out-of-pocket treatment costs (AOR = 1.68; 95% CI: 1.06-2.67), being in the continuation phase (AOR = 1.83; 95% CI: 1.12-2.98), not receiving counselling (AOR = 7.25; 95% CI: 3.86-13.61), and currently smoking (AOR = 2.05; 95% CI: 1.16-3.60) had greater odds of dissatisfaction with TB care.</p><p><strong>Conclusion: </strong>Nearly half of the TB patients were not satisfied with TB care. Policymakers and healthcare providers should address the determinants of dissatisfaction, particularly socioeconomic barriers, healthcare inequities, limited counselling, and regional disparities, to improve TB care programs in Southern Afghanistan.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"602353"},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13134556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment-Related Factors for Medication Non-Adherence Among Patients with Major Depressive Disorder: An Explanatory Sequential Mixed-Methods Study.","authors":"Sohail Riaz, Fazli Khuda, Asif Jan, Aqeel Nasim, Atif Ali Khan Khalil, Basmah Abdulaziz Albabtain, Sultan Mehtap Büyüker, Asmat Ullah","doi":"10.2147/PPA.S554649","DOIUrl":"https://doi.org/10.2147/PPA.S554649","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to examine treatment-related factors influencing antidepressant non-adherence among patients with Major depressive disorder in Pakistan.</p><p><strong>Methods: </strong>An explanatory sequential mixed-methods cross-sectional design was employed. The study first conducted questionnaire-based quantitative research to assess non-adherence and its treatment-related predictors. This was followed by semi-structured interviews with a purposively selected subset of participants who were poorly adherent to explore their contextual experiences. Quantitative and qualitative findings were integrated using narrative synthesis and joint displays.</p><p><strong>Results: </strong>A total of 2,513 participants with recurrent major depressive disorder (MDD) were surveyed. Among them, 812 (32.3%) were classified as poorly adherent, 719 (28.6%) as moderately adherent, and 982 (39.1%) as highly adherent, based on the UMGLS-4. High ADR burden, low DAI-10 scores, unemployment, low income, and age above 55 years were significantly associated with non-adherence (p <0.05). Participants with high ADR burden were 1.42 times more likely to be non-adherent (AOR = 1.42, p < 0.001). Qualitative findings from 17 interviews supported and expanded these associations, revealing how sedation, weight gain, cultural interpretations of medication as \"hot\", lack of treatment timelines, and poor pharmacy support discouraged routine antidepressant use.</p><p><strong>Conclusion: </strong>A combination of physiological, cognitive, and systemic treatment-related barriers drives antidepressant non-adherence among Pakistani MDD patients. Addressing these factors through culturally sensitive ADR counselling, consistent follow-up, and pharmacist-led support may improve adherence and treatment outcomes in low-resource mental health settings.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"554649"},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prioritisation of Factors Influencing Outpatient Satisfaction in Chinese Public Hospitals: A Dominance Analysis.","authors":"Wei Liu, Guoping Li, Kunli Ding, Sike Wang, Zixuan Fan, Zhenbo Wang, Qian Zhuang, Yang Liu, Lihua Liu, Lin Li","doi":"10.2147/PPA.S553147","DOIUrl":"https://doi.org/10.2147/PPA.S553147","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the current status of outpatient satisfaction with their healthcare experience and its influencing factors, providing a basis for improving medical service quality.</p><p><strong>Methods: </strong>Utilizing data from a 2021-2024 national survey by Doctor-Patient Experience Research Base, National Health Commission of the people's Republic of China across 20 hospitals (n=49,371 outpatients), this study analyzed the impact of hospital characteristics, patient demographics, and care process factors (registration time, consultation time, payment time, waiting time, perceived value of consultation) on satisfaction. Chi-square tests and Logistic regression identified significant factors; the innovative application of dominance analysis was then used to assess their relative importance contribution and establish a clear priority for intervention.</p><p><strong>Results: </strong>Hospital characteristics, care process factors, and most patient demographics showed significant associations with satisfaction (p<0.05). Logistic regression identified consultation time, perceived value of consultation, payment time, registration time, and waiting time as significant predictors of satisfaction (p<0.001). The dominance analysis revealed a distinct hierarchy of influence: consultation time had the highest relative contribution to satisfaction, followed by perceived value of consultation, payment time, registration time, and waiting time.</p><p><strong>Conclusion: </strong>This study analyses the key sequences for enhancing patient satisfaction and healthcare experience, providing healthcare managers with precise actionable guidance.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"553147"},"PeriodicalIF":2.0,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}