{"title":"Undetectable=Untransmittable Perception and Its Association with Sexual Risk Behaviors and Potential Physical and Psychological Benefits Among People Living with HIV/AIDS in Hunan, China.","authors":"Yuqiong Duan, Yixuan Li, Ziqi Qin, Pingwu Wang, Tao Liu, Honghong Wang, Xueling Xiao","doi":"10.2147/PPA.S544362","DOIUrl":"https://doi.org/10.2147/PPA.S544362","url":null,"abstract":"<p><strong>Purpose: </strong>Undetectable = Untransmittable (U=U) is the scientific consensus that people living with HIV (PLWH) who maintain an undetectable viral load cannot sexually transmit HIV to others. This study aimed to explore the status of PLWH's perception of U=U (including knowledge, attitude, and acceptance) and the relationships with their sexual behaviors and potential physical and psychological benefits (satisfaction of health, depression, self-stigma, quality of life, ART adherence, viral load and CD4+ cell level).</p><p><strong>Patients and methods: </strong>We analyzed data from 730 PLWH aged 18 years or older from the outpatient clinic at the Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, between October 2021 and January 2022. Data were collected using a structured, anonymous, paper-based questionnaire. It gathered information on U=U perception, sexual risk behaviors, potential physical and psychological benefits and socio-demographic and clinical characteristics. To examine associations between U=U perception and sexual risk behaviors and potential physical and psychological benefits, for categorical outcome variable, multiple logistic regression was adopted for the CD4+ cells and HIV viral load level; for count outcome variable, generalized linear model (GLM) with Poisson regressor was used for sexual risk behaviors; and since all the other response variables were skewed, GLM with Gamma regressor was used.</p><p><strong>Results: </strong>The mean age of the participants was 33.6 years (SD = 10.8). Majority (95.1%) of the participants were male and initiated ART (97%). Nearly half had bachelor's degree or higher (45.6%) and were identified as homosexuality (48.5%). More than half heard U=U (63.8%) and perceived U=U accurate (57.4%), however only 13.6% had a comprehensive understanding of U=U and 19.9% accepted U=U as a strategy for HIV prevention. The acceptance level of U=U was positively correlated with increased unprotected sexual behaviors [β(95% CI)=0.21(0.045,0.365); P<0.05)]. The U=U perception was not related to depression, antiretroviral therapy adherence, self-stigma and perceived quality of life. We only found that less U=U knowledge was associated with the detectable [β(95% CI)=0.69(0.503,0.903); P<0.05)] or unavailable viral load [β(95% CI)=0.68(0.0528,0.884); P<0.01)], and unavailable CD4+ cell counts was more like to less U=U knowledge [β(95% CI)=0.62(0.395,0.959); P<0.05)]. Furthermore, those with unavailable viral data exhibited a more negative attitude towards U=U [β(95% CI)=0.79(0.635,0.977); P<0.05)]. In addition, lower level of U=U acceptance was related to the unavailable CD4 cell counts [β(95% CI)=0.67(0.474,0.940); P<0.05)].</p><p><strong>Conclusion: </strong>This study suggests that PLWH have not fully reaped the benefits of U=U. Further research is necessary to explore strategies for promoting clear and accurate information about U=U and for effectively communi","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3057-3068"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Medication Self-Management at Home Among Older Adults with Coronary Artery Disease: A Qualitative Study.","authors":"Mengqi Xu, Suzanne Hoi Shan Lo, Lingyan Zhu, Xiaoli Huang","doi":"10.2147/PPA.S537115","DOIUrl":"https://doi.org/10.2147/PPA.S537115","url":null,"abstract":"<p><strong>Background: </strong>The medication self-management at home among older adults with coronary artery disease is found suboptimal, leading to discrepancies from the prescriptions. More support is expected to meet their needs in medication self-management. This study aims to understand medication self-management at home of older adults with coronary artery disease.</p><p><strong>Methods: </strong>From June to August 2024, a descriptive qualitative study was conducted among 28 older adults with coronary artery disease and six healthcare professionals. Older adults participated in interviews before and one month after hospital discharge. The healthcare professionals were interviewed once. The semi-structured interviews were conducted face-to-face or through a virtual platform. Thematic analysis was used in data analysis.</p><p><strong>Findings: </strong>Two themes with five sub-themes emerged: 1. Dealing with unknown when starting new regimens: seeking support from healthcare professionals when starting medication self-management, self-information seeking is far from satisfactory. 2. Exploring strategies to support adherence to medications: difficulties in integrating medication taking into daily routine, aids as reminders for medication taking, and requesting help from caregivers.</p><p><strong>Conclusion: </strong>Older adults with coronary artery disease struggled with seeking information to adapt to the new regimens and exploring different strategies to improve their adherence. Future interventions could improve their medication self-efficacy through patient-centred communication and peer education. Offering reliable information resources and improving the capacity to identify the accuracy of online information were important for self-information seeking. Besides, support in medication management aids and involving caregivers in medication management according to their needs were also warranted.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3069-3082"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identifying Causes of Subcutaneous Immunotherapy Non-Adherence in Patients with Allergic Rhinitis: A Cross-Sectional Study.","authors":"Cheng-Zhi Huang, Zhi-Yuan Tang","doi":"10.2147/PPA.S544333","DOIUrl":"https://doi.org/10.2147/PPA.S544333","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the reasons for discontinuation of subcutaneous immunotherapy (SCIT) in patients with allergic rhinitis (AR) and to inform strategies for improving treatment adherence.</p><p><strong>Materials and methods: </strong>In this single-center retrospective cross-sectional study, 794 AR patients (age 1-60 years) who initiated standardized SCIT with house dust mite extracts at Shenzhen University General Hospital between December 2019 and July 2023 were included. SCIT followed a structured dose-escalation and maintenance protocol: weeks 1-4, 0.1-0.8 mL (50 TU/mL); weeks 5-8, 0.1-0.8 mL (500 TU/mL); weeks 9-14, 0.1-1.0 mL (5000 TU/mL); weeks 14-152, monthly 1.0 mL (5000 TU/mL). Symptom severity was assessed using a visual analogue scale (VAS) at baseline and at 6 months, 1, 2, and 3 years; <20% VAS reduction and/or patient-reported insufficient improvement after ≥12 months defined \"unsatisfactory efficacy\". Structured telephone follow-up was used, with caregivers interviewed for pediatric patients. All patients provided detailed contact information; no loss to follow-up occurred.</p><p><strong>Results: </strong>Fifty-eight patients (7.30%) discontinued SCIT (27 males, 31 females; mean age 14.71 ± 10.76 years). Leading reasons were relocation for education, work, or travel (53.45%), perceived lack of efficacy (17.24%), limited time (8.62%), and pregnancy/gynecological conditions (6.90%). Females were more likely to discontinue due to relocation, males due to unsatisfactory efficacy; age and comorbidities were not significantly associated with dropout.</p><p><strong>Conclusion: </strong>SCIT discontinuation was mainly driven by relocation, treatment expectations, and logistical factors, with gender-specific patterns. Tailored pre-treatment counseling, assessment of lifestyle and reproductive plans, and strategies to maintain continuity of care may reduce dropout and improve long-term adherence.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3049-3056"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristian Ramos-Vera, Miguel Basauri-Delgado, Alicia Krikorian, Yaquelin E Calizaya-Milla, Jacksaint Saintila
{"title":"Predictors of Self-Care Self-Efficacy in Adults Familiar with Palliative Care: The Role of Patient-Centered Communication, Health, and Well-Being.","authors":"Cristian Ramos-Vera, Miguel Basauri-Delgado, Alicia Krikorian, Yaquelin E Calizaya-Milla, Jacksaint Saintila","doi":"10.2147/PPA.S529645","DOIUrl":"10.2147/PPA.S529645","url":null,"abstract":"<p><strong>Background: </strong>Understanding the determinants of self-care self-efficacy (SS) is essential to improving health outcomes in patients facing advanced disease. This study contributes to the field by examining the direct and indirect effects of quality of care (QC), patient-centered communication (PCC), perceived health (PH), and emotional well-being (EW) on SS in American adults with knowledge of palliative care.</p><p><strong>Methods: </strong>A predictive-crossover design study was conducted. Data from N = 1154 adult respondents to the 2018 Health Information National Trends Survey (HINTS) 5, cycle 2 were used. Structural Equation Modeling (SEM) was used to report the direct and indirect effects for the proposed mediation model.</p><p><strong>Results: </strong>QC had a strong, significant association with PCC (β =0.930, p <0.001). PCC was significantly associated with PH (β =0.104, p <0.01) and EW (β =0.098, p <0.01), but not directly with SS (β =0.030, p >0.05). SS was significantly predicted by PH (β =0.659, p <0.001) and EW (β =0.178, p <0.001). Indirect effects of PCC on SS via PH and EW were confirmed.</p><p><strong>Conclusion: </strong>These findings highlight the importance of promoting perceived health and emotional well-being as key mechanisms by which care quality and communication impact self-efficacy. This study underscores the need to prioritize patient perceptions in palliative care interventions aimed at enhancing self-care capacity.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3025-3035"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Influencing Rehabilitation Exercise Behavior in Elderly Rotator Cuff Repair Patients: A Qualitative Study Based on the Theory of Behavior Change Wheel.","authors":"Qi Tang, Fang Hu, Jie Zhao, Nan Wang","doi":"10.2147/PPA.S546831","DOIUrl":"10.2147/PPA.S546831","url":null,"abstract":"<p><strong>Purpose: </strong>With the incidence of elderly patients requiring rotator cuff repair, it is crucial to investigate the factors influencing rehabilitation exercise behavior. The theory of the behavior change wheel is used to analyze the factors that influence an individual's health behaviors. This study aimed to explore factors that can influence rehabilitation exercise behavior in elderly rotator cuff repair patients based on the theory of behavior change wheel. This is a qualitative study using thematic analysis.</p><p><strong>Methods: </strong>Data was collected through face-to-face interviews with 15 elderly rotator cuff repair patients in the traumatic upper limbs unit of the Tianjin Hospital. This study adhered to the targeted thematic analysis based on the theory of behavior change wheel.</p><p><strong>Results: </strong>Three themes and seven sub-themes were identified, including rehabilitation exercise capability-related factors (rehabilitation exercises exacerbate postoperative pain, postoperative discomfort, lack of knowledge of rehabilitation exercises), the influence of external environmental opportunity-related factors (supervision and encouragement by primary family caregivers, support and guidance from healthcare professionals), and motivation-related factors for adherence to rehabilitation exercise behavior (health beliefs, rehabilitation expectations).</p><p><strong>Conclusion: </strong>This study reveals that the rehabilitation exercise behavior in elderly rotator cuff repair patients is influenced by factors related to capability, opportunity, and motivation. Reducing postoperative pain, enhancing health belief, setting reasonable rehabilitation expectation, emphasizing social support, and expanding access to proactive information will contribute to improving the quality of rehabilitation exercises. Future research should expand the scope to include family members and caregivers to conduct a more comprehensive exploration of the influencing factors.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3037-3047"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sihui Liu, Kaili Hu, Huazhen Rui, Yi Gao, Xue Zhan
{"title":"Barriers and Facilitators in Proxy Decision-Making for Financial Support in Adolescent Idiopathic Scoliosis: A Qualitative Study of Family Caregivers Using the COM-B Model.","authors":"Sihui Liu, Kaili Hu, Huazhen Rui, Yi Gao, Xue Zhan","doi":"10.2147/PPA.S538568","DOIUrl":"10.2147/PPA.S538568","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to explore the barriers and facilitators faced by family caregivers in proxy decision-Making for financial support in patients with adolescent idiopathic scoliosis (AIS).</p><p><strong>Patients and methods: </strong>This qualitative study utilized the Capability, Opportunity, Motivation-Behavior (COM-B) model to examine the factors that influence family caregivers' proxy decision-Making regarding financial support for patients with AIS. Eighteen caregivers were interviewed using semi-structured interviews. The data were analyzed using MAXQDA software and Braun and Clarke's thematic analysis.</p><p><strong>Results: </strong>The key facilitators identified included financial relief, trust in the legitimacy and reputation of charitable organizations, and family and social support. Barriers included lack of knowledge and practical skills, emotional and physical exhaustion, privacy concerns, particularly related to the patient's future educational opportunities, and the complexity of application procedures.</p><p><strong>Conclusion: </strong>This study underscores the importance of addressing the barriers caregivers face, such as complex application processes and emotional stress, while enhancing facilitators like financial support and trust in organizations. Streamlining application procedures and improving transparency can enhance caregivers' ability to access financial resources, benefiting both patients and their families.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3001-3011"},"PeriodicalIF":2.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12478196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Cross-Sectional Study of Quality of Life, Treatment Adherence, and Health-Seeking Behavior in Turkish Patients with Rheumatoid Arthritis: Gender and Education as Key Predictors.","authors":"Betülay Kilic, Emine Akdoğan, Fatma Ilknur Cinar, Melih Pamukcu, Filiz Bozdeveci","doi":"10.2147/PPA.S553233","DOIUrl":"10.2147/PPA.S553233","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to examine the quality of life, treatment adherence, and health-seeking behavior among patients with rheumatoid arthritis.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted with 161 patients diagnosed with rheumatoid arthritis between May 2024 and May 2025. Data were collected using the \"Personal Information Form\", \"Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL)\", \"Compliance Questionnaire on Rheumatology (CQR-T)\", and the \"Health-Seeking Behavior Scale\".</p><p><strong>Results: </strong>The mean age of the participants was 57.94 ± 13.46 years, and 72% were female. The mean duration of symptoms was 12.95 ± 10.06 years, and the mean disease activity score was 6.09±2.59. The analyses showed that lower treatment adherence, greater symptom severity, and female gender had negative effects on quality of life, while higher disease activity had a positive effect (ß = -0.205; ß = -0.284; ß = -0.155; ß = 0.303, respectively). In addition, a decrease in quality of life was found to negatively affect treatment adherence, whereas professional health-seeking behavior improved adherence (ß = -0.164; ß = 0.519). Educational level was also found to have a positive effect on health-seeking behavior (ß = 0.304).</p><p><strong>Conclusion: </strong>This study highlights the complex interplay of psychosocial, behavioral, and clinical factors influencing quality of life in patients with rheumatoid arthritis. Specifically, we found that male gender was a significant predictor of better quality of life, while higher education levels were associated with stronger health-seeking behavior. These findings underscore the importance of strengthening treatment adherence, promoting proactive health-seeking behavior, and considering sociodemographic differences such as gender and education in patient care. Moreover, this study is among the first to examine health-seeking behavior alongside quality of life and treatment adherence in RA, providing a unique contribution to the literature. Integrating these factors into management strategies can better support clinicians in improving both health outcomes and quality of life for their patients. This study highlights the complex interplay of psychosocial, behavioral, and clinical factors influencing quality of life in patients with rheumatoid arthritis. The findings underscore the importance of strengthening treatment adherence, promoting proactive health-seeking behavior, and considering sociodemographic differences such as gender and education in patient care. Moreover, this study is among the first to examine health-seeking behavior alongside quality of life and treatment adherence in RA, providing a unique contribution to the literature. Integrating these factors into management strategies can better support clinicians in improving both health outcomes and quality of life for their patients.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"3013-3024"},"PeriodicalIF":2.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12478224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Misk Al Zahidy, Kerly Guevara Maldonado, Suvyaktha Simha, Mariana Borras-Osorio, Megan E Branda, Viet-Thi Tran, Jennifer L Ridgeway, Victor M Montori
{"title":"Development of the TBQ+D: A Novel Patient-Reported Measure of The Burden of Digital Care.","authors":"Misk Al Zahidy, Kerly Guevara Maldonado, Suvyaktha Simha, Mariana Borras-Osorio, Megan E Branda, Viet-Thi Tran, Jennifer L Ridgeway, Victor M Montori","doi":"10.2147/PPA.S540026","DOIUrl":"10.2147/PPA.S540026","url":null,"abstract":"<p><strong>Background: </strong>Patients with diabetes manage complex treatment regimens that include the use of digital medicine tools. Existing instruments do not explicitly capture treatment burden, i.e., workload and its effect on patient's quality of life, from using digital medicine tools.</p><p><strong>Objective: </strong>To engage patients and clinical experts in adapting the Treatment Burden Questionnaire (TBQ) to capture digital treatment burden. The adapted instrument underwent cognitive testing and refinements to ensure it captures the burden of using digital medicine tools in diabetes self-management.</p><p><strong>Methods: </strong>This two-phase study was conducted with adults with diabetes at the Division of Endocrinology at Mayo Clinic (Rochester, MN). First, we mapped themes from prior concept elicitation interviews to existing TBQ items to identify content gaps related to digital burden. Based on these gaps, the study team and expert panel generated new items and adapted existing ones to better reflect the workload and burdens from using digital medicine tools. The resulting instrument underwent three rounds of cognitive testing with adult patients living with diabetes, using a think-aloud protocol to assess clarity, relevance, and comprehensiveness. Results of cognitive testing informed iterative refinements across three rounds of interviews, leading to improved clarity, reduced redundancy, and improved relevance of items.</p><p><strong>Results: </strong>The final TBQ+D retained the original 15-item TBQ structure, added 8 new items, and modified 8 extant ones to capture burden of digital care (e.g, syncing issues, discomfort from sensors, and device malfunctions). Cognitive testing demonstrated strong content relevance and patient comprehension.</p><p><strong>Conclusion: </strong>The TBQ+D can measure digital treatment burden in patients with diabetes. Limitations include a relatively homogeneous sample drawn from a single center. Next steps include field testing for validation across diverse populations and settings.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2975-2984"},"PeriodicalIF":2.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Systematic Review of Internet-Based Remote Patient Monitoring Systems for Chronic Disease Management in Asian.","authors":"Etika Emaliyawati, Kusman Ibrahim, Titis Kurniawan, Nita Fitria, Praneed Songwathana","doi":"10.2147/PPA.S544351","DOIUrl":"10.2147/PPA.S544351","url":null,"abstract":"<p><strong>Background: </strong>Chronic diseases are an increase global health concern driven by aging populations and lifestyle changes. In Asia, rapid demographic shifts and diverse healthcare systems pose unique challenges for chronic disease management. Internet-based remote monitoring systems offer innovative solutions for early detection and timely intervention, but their effectiveness within the varied Asian context requires thorough evaluation.</p><p><strong>Purpose: </strong>This systematic review aimed to evaluate the effectiveness of internet-based remote monitoring systems in managing outcomes among patients with chronic diseases.</p><p><strong>Methods: </strong>A systematic literature search was conducted across major electronic databases, including PubMed, Scopus, Taylor and Francis, and EBSCOhost, employing a combination of relevant search terms. The keywords used were \"remote monitoring OR telemonitoring OR internet-based monitoring AND chronic disease OR chronic illness AND patient outcome OR health outcome OR clinical outcome\". The inclusion criteria are defined using the PICO framework. The data were analyzed descriptively and qualitatively using thematic analysis.</p><p><strong>Results: </strong>Following rigorous screening and quality appraisal, 16 studies met the inclusion criteria. These studies employed diverse remote monitoring modalities, encompassing automated remote monitoring systems, patient-reported monitoring, and personalized telecommunication-based approaches. The evidence demonstrates that internet-based remote monitoring systems significantly enhance chronic disease management across various Asian contexts.</p><p><strong>Conclusion: </strong>Internet-based remote patient monitoring constitutes a pivotal advancement in chronic disease management. It facilitates timely emergency responses, reduces healthcare utilization, and optimizes clinical outcomes within Asian healthcare settings. Future efforts should focus on synergizing automated data acquisition, patient self-reporting, and personalized communication to overcome challenges related to sustained behavioral change and quality-of-life improvements.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2985-3000"},"PeriodicalIF":2.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asma Basheer Khamees, Rasha M Arabyat, Ibrahim Alabbadi, Saja A Alnahar
{"title":"Association Between Adherence to Oral Antidiabetic Medications and Cost Sharing Among Patients with Type II Diabetes: A Cross-Sectional Study.","authors":"Asma Basheer Khamees, Rasha M Arabyat, Ibrahim Alabbadi, Saja A Alnahar","doi":"10.2147/PPA.S532590","DOIUrl":"10.2147/PPA.S532590","url":null,"abstract":"<p><strong>Background: </strong>One of the critical factors that affect medication adherence is cost-sharing (the percentage that a patient pays out-of-pocket to cover health expenses), which sometimes may become a barrier to initiate or refill prescription medications.</p><p><strong>Aim: </strong>The primary aim of this study was to assess the association between adherence to oral antidiabetic medications (OADs) using the Adherence to Refills and Medicines Scale for Diabetes (ARMS-D) questionnaire and cost-sharing among patients with type 2 diabetes. The secondary aim was to evaluate the extent to which patients are adherent to their OADs, and which factors were significantly affecting patients' adherence to their OADs.</p><p><strong>Methods: </strong>Four hundred adult patients that visited the Diabetes Clinic of the Jordan University Hospital who were on OADs were interviewed by the researcher and were asked to complete the study questionnaire. The questionnaire consists of two sections: patients' characteristics and ARMS-D. Simple and multivariable linear regression analyses were used to assess the determinants (demographic, clinical, and economic characteristics) associated with patient's adherence to their OADs.</p><p><strong>Results: </strong>When measured by ARMS-D (sores range from 11 to 44), where higher scores indicate lower adherence, 71% of participants reported lower adherence (scores > 11) to their OADs, while 29% achieved full adherence (scores = 11). Our analysis identified that there was no significant association between adherence to OADs and cost-sharing (<i>P</i> > 0.05). However, multiple regression analysis revealed that demographic factors, such as age and education level, along with clinical factors, such as the number of pills per day, the number of anti-diabetic-medications side effects, and frequent episodes of hyperglycemia, were significantly affecting patients' adherence to OADs (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The key findings of this study indicate that the effect of patients' characteristics on adherence is therefore caused primarily by demographic and clinical factors rather than economic factors.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2959-2973"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12471656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}