Patient preference and adherence最新文献

{"title":"Improving Proton-Pump Inhibitor Adherence Intervention Between Primary Care and Community Pharmacies: A Pre-Post Intervention Study.","authors":"María Puig-Moltó, Blanca Lumbreras, Elsa López-Pintor","doi":"10.2147/PPA.S485307","DOIUrl":"https://doi.org/10.2147/PPA.S485307","url":null,"abstract":"<p><strong>Purpose: </strong>Proton-pump inhibitor (PPI) therapy stands as the primary treatment for upper gastrointestinal symptoms, yet poor adherence often results in treatment failure. Given that patients experiencing these symptoms frequently seek assistance at community pharmacies, the development of collaborative tools with primary care is becoming imperative. The objective was to assess the effectiveness of a pharmaceutical intervention, as demonstrated by a collaborative model between primary care and community pharmacies, in enhancing adherence to PPI among patients experiencing upper gastrointestinal symptoms.</p><p><strong>Patients and methods: </strong>A Pre-post intervention study was carried out in Spanish community pharmacies (June-October 2022). During the baseline visit, patients' sociodemographic and clinical variables were evaluated. Patients were categorized as adherent or non-adherent using the Morisky Medication Adherence Scale (MMAS-4). In the follow-up visit (14 days later), the impact of the intervention was measured by changes in the Gastroesophageal Reflux Disease Impact Scale (GIS).</p><p><strong>Results: </strong>Of the 351 patients with an active PPI prescription, 178 (50.7%) were non-adherent. Nearly 70% of these patients (122, 68.5%) received an intervention to improve adherence. The overall GIS score improved after the intervention (mean 25.34, SD 5.66 vs mean 27.64, SD 5.63, p < 0.001). All GIS score items showed improvement after the intervention except for the item regarding the taking of additional medication different from that prescribed by the clinician (p = 0.200).</p><p><strong>Conclusion: </strong>The pharmaceutical intervention had a positive impact on patients' symptom relief and overall quality of life, highlighting the significance and efficacy of a collaborative model between primary care and professional pharmaceutical services.</p><p><strong>Clinical trials registry: </strong>Clinical Trial Registration (NCT05162079).</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2569-2580"},"PeriodicalIF":2.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors to Poor Quality of Life Among Patients with Heart Failure and Its Correlation with Their Medication Adherence: Finding for Healthcare Improvement and Follow-Up.","authors":"Sameer A Alkubati, Homoud Khaled Aleyadah, Mohammad Alboliteeh, Abdulhafith Alharbi, Bandar Alsaif, Bushra Alshammari, Anas Balawi","doi":"10.2147/PPA.S503087","DOIUrl":"https://doi.org/10.2147/PPA.S503087","url":null,"abstract":"<p><strong>Background: </strong>Understanding medication adherence and its relationship with quality of life (QoL) is essential for improving health outcomes in patients with heart failure (HF).</p><p><strong>Objective: </strong>This study aimed to investigate the predictors of poor quality of life and its relationship with medication adherence among patients with heart failure.</p><p><strong>Methods: </strong>A cross-sectional correlational study was performed on 229 patients with HF receiving care at the Cardiac Center of King Salman Specialist Hospital from March to June 2024. Data were collected using a structured questionnaire comprising patient demographics, the Minnesota Living with Heart Failure Questionnaire (MLHFQ) to assess QoL, and the General Medication Adherence Scale (GMAS) to measure medication adherence.</p><p><strong>Results: </strong>The mean medication adherence score among patients with heart HF was 17.53 ± 6.94. The level of adherence was moderate among most patients (47.2%), high (29.7%), and poor (23.1%). Regarding QoL, the mean total score for overall QoL was 42.16 ± 20.53. Specifically, the mean scores were 15.24 ± 8.65 and 10.53 ± 5.82 for the physical and emotional dimensions of QoL, respectively. More than half of the patients experienced poor QoL, while moderate QoL was observed in 31.9% and good QoL in 17% of patients. Furthermore, there were moderate negative correlations between medication adherence and physical QoL (r= -0.51), emotional QoL (r = -0.59), and overall QoL (r = -0.59), all of which were statistically significant (p <0.001).</p><p><strong>Conclusion: </strong>Moderate-to-poor levels of medication adherence and QoL were found among HF patients receiving care in Hail City. Therefore, interventions to improve medication adherence among patients with HF must be prioritized to enhance health outcomes and QoL. It is also crucial to address the factors that negatively influence medication adherence to overcome the barriers that hinder optimal medication adherence.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2545-2557"},"PeriodicalIF":2.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapy-Related Symptoms and Sense of Coherence: The Mediating Role of Social Support and Hope in Lung Cancer Patients Undergoing Chemotherapy.","authors":"Fang Wang, Anliu Nie, Shaona Liao, Zhisheng Zhang, Xiangfen Su","doi":"10.2147/PPA.S480306","DOIUrl":"https://doi.org/10.2147/PPA.S480306","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the current status of the sense of coherence in lung cancer patients undergoing chemotherapy and explore the mediating role of social support and hope in the relationship between therapy-related symptoms and sense of coherence.</p><p><strong>Methods: </strong>We conducted a cross-sectional study to investigate lung cancer chemotherapy patients aged 18 years or older who completed at least two cycles of chemotherapy. Patients were recruited from the First Affiliated Hospital of Guangzhou Medical University's chemotherapy day ward from May to December 2023. Patients were required to complete a questionnaire that included the Sense of Coherence Scale, the Perceived Social Support Scale, the Herth Hope Index, and the Therapy-related Symptoms Checklist. The structural equation model was used to test the mediating role of social support and hope between therapy-related symptoms and the sense of coherence.</p><p><strong>Results: </strong>A total of 241 patients were included. The scores of the sense of coherence, hope level, therapy-related symptoms, and social support were 68.79 ± 11.24, 38.94 ± 4.25, 11.53 ± 8.15, and 69.49 ± 8.15, respectively. Sense of coherence, social support, hope, and therapy-related symptoms were significantly related (P<0.01). Therapy-related symptoms had a direct negative influence on the sense of coherence [B=-0.144, 95% CI (-0.209, -0.070)]. Meanwhile, therapy-related symptoms influenced the sense of coherence via three pathways: independent mediation of social support [B=-0.021, 95% CI (-0.065, -0.002)], independent mediation of hope [B=-0.022, 95% CI (-0.057, -0.000)], and chain mediation of social support and hope [B=-0.012, 95% CI (-0.035, -0.002)].</p><p><strong>Conclusion: </strong>Lung cancer patients undergoing chemotherapy experience a medium sense of coherence. This study's findings indicate that the relationship between therapy-related symptoms and sense of coherence is affected by the independent mediating effect of social support and hope and the chain mediating effect of social support and hope. Therefore, reducing the burden of their therapy-related symptoms, providing them with social support, and fostering their hope can enhance patients' sense of coherence and improve their quality of life.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2559-2568"},"PeriodicalIF":2.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Patient Satisfaction Attaining Primary Health Care Services at Health Centers in Mogadishu, Somalia.","authors":"Hassan Ali Abdi, Mohamed Omar Warsame, Mohamud Abdinor Adan, Mohamed Ahmed Hassan","doi":"10.2147/PPA.S486919","DOIUrl":"https://doi.org/10.2147/PPA.S486919","url":null,"abstract":"<p><strong>Background: </strong>Patient satisfaction in healthcare a crucial aspect of quality assessment, especially in resource-limited settings like Mogadishu, Somalia, where challenges in service quality persist due to socioeconomic and infrastructural constraints. It plays a significant role in evaluating the overall healthcare experience and provides valuable insights into healthcare system strengths and weaknesses.</p><p><strong>Objective: </strong>This study aimed to assess patient satisfaction in primary health care facilities in Mogadishu to identify areas for improvement.</p><p><strong>Methodology: </strong>A facility-based cross-sectional survey of 358 patients was conducted from August 2023 to November 2023; Data was collected through questionnaires and analyzed using SPSS software. Quantitative data was analyzed using appropriate statistical methods, such as descriptive statistics and chi-square tests, to examine the relationships between patient satisfaction and various factors the statistical significance was declared at p-value < 0.05. Ethical approval was obtained from the Ministry of health Somalia before data collection permission was also obtained from the health facility in charges.</p><p><strong>Results: </strong>While a majority of respondents, 71.5% express overall satisfaction with the healthcare services provided, there were significant concerns regarding empathy, privacy, facility cleanliness, and waiting times. There is a statistically significant association between patients' visit frequency and their perceptions of various healthcare aspects. Patients who visited the healthcare facility 2-4 times expressed significantly more positive perceptions of healthcare providers' competence (p < 0.020), empathy (p < 0.009), time spent (p < 0.001), pharmacy services (p < 0.001), and facility cleanliness (p < 0.001) when compared to those with first-time visits or more frequent visits.</p><p><strong>Conclusion: </strong>The study highlights the importance of addressing communication gaps, enhancing facility hygiene, and reducing waiting times to improve patient satisfaction. To enhance patient satisfaction and overall healthcare quality, recommendations include healthcare provider training, facility hygiene upgrades, and the implementation of strengthened privacy protocols in Mogadishu's primary healthcare facilities.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2529-2543"},"PeriodicalIF":2.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with the Public's Intention to Report Adverse Drug Reactions to Community Pharmacists in the Makkah Region of Saudi Arabia: An Application of the Theory of Planned Behavior.","authors":"Fahad T Alsulami","doi":"10.2147/PPA.S495487","DOIUrl":"10.2147/PPA.S495487","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the public's intention to report ADRs to community pharmacists in the Makkah region of Saudi Arabia and to identify the factors influencing this intention, using the TPB as the theoretical framework.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in the Makkah region of Saudi Arabia via a nonprobability sampling method. Data were gathered through an online self-report survey designed to assess the public's intention to report ADRs to community pharmacists. Multivariate logistic regression analysis was used to examine the influence of three constructs of the TPB on this intention.</p><p><strong>Results: </strong>A total of 452 individuals participated in the study. Approximately 22% of them reported experiencing ADRs in the last six months, but only 21% were aware of the Saudi NPC. Approximately 62% of the participants expressed a strong intention to report ADRs to community pharmacists. The public exhibited a highly positive attitude toward reporting ADRs, alongside high subjective norms and perceived behavioral control. Among the TPB constructs, attitude had the most significant influence on the intention to report ADRs to community pharmacists, followed by subjective norms and perceived behavioral control.</p><p><strong>Conclusion: </strong>This study revealed a strong public intention to report ADRs to community pharmacists in the Makkah region, driven primarily by positive attitudes, supportive subjective norms, and high perceived behavioral control. However, the findings highlight a critical gap in public awareness of the Saudi NPC, with only 21% of participants aware of its existence. These results underscore the importance of targeted initiatives to improve awareness of the Saudi NPC and to leverage positive attitudes and social norms to promote ADR reporting practices effectively.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2495-2506"},"PeriodicalIF":2.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicine Usage for Hypertension Management in Type 2 Diabetes Patients in the Rural-Urban Fringe Zone, Suzhou City, Jiangsu Province, China.","authors":"Liping Wang, Jin Yan, Fenghua Wang, Peng Xue, Zheng Li, Rong Jiang, Min Lu, Ning Yang, Junli Wei, Maoti Wei, Zhimin Ma","doi":"10.2147/PPA.S475936","DOIUrl":"10.2147/PPA.S475936","url":null,"abstract":"<p><strong>Objective: </strong>Medicine is critical for blood-pressure control in patients with type 2 diabetes mellitus (T2DM), for evaluation of treatment patterns and effects would offer baselines for future health services.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from August 2018 to January 2021 in the urban-rural fringe zone of Suzhou City, Jiangsu Province, China. Blood pressure and antihypertensive medication use were collected from T2DM patients combined with hypertension (HTN). Using systolic blood pressure (SBP) and diastolic blood pressure (DBP) <140/85 mmHg as HTN controls, medicine usage patterns were analyzed.</p><p><strong>Results: </strong>Among the 931 T2DM patients with HTN, 333 (37.0%, 95% <i>CI</i>: 33.8%-40.2%) had HTN controlled with SBP and DBP of <140/85 mmHg. Partial following the medicine recommendations for HTN control were observed in this zone, and calcium channel blocker (CCB), angiotensin II receptor blocker (ARB), diuretics and β-receptor blocker (Βeta-blocker) were the most frequently used ones, especially for CCB and ARB, which accounted for 67% (625/931) and 55% (509/931), respectively. For combination usage, complete adherence to the recommendation was observed, ie, ARB + CCB and ARB + diuretics were listed as the top two, accounting 30% (282/931) and 16% (153/931), respectively. Combination therapies had HTN control rates ranging from 31.1% to 39.1%, lower than those of monotherapy (>40%). In monotherapies, CCB had control rate of 41.2% (115/279, 95% <i>CI</i> 35.4%-47.2%), higher than combination (31.9%, 105/329, 95% <i>CI</i> 26.9%-37.3%), as well as ARB; the single reagent had control rate of 42.0% (95% <i>CI</i> 33.7%-50.7%), higher than combination (32.2%, 95% <i>CI</i> 27.4%-37.3%).</p><p><strong>Conclusions: </strong>More than 60% of T2DM patients had blood-pressures above the target level and the pattern of medications for HTN control in T2DM patients followed the recommendation of the authorities; however, the effects were not as expected, and more antihypertensive medicines or combinations would not raise the HTN control rate.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2519-2528"},"PeriodicalIF":2.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytomedicines in Pharmacotherapy of LUTS/BPH - What Do Patients Think?","authors":"Alexander Tamalunas, Richard Paktiaval, Philipp Lenau, Leo Federico Stadelmeier, Alexander Buchner, Thomas Kolben, Giuseppe Magistro, Christian G Stief, Martin Hennenberg","doi":"10.2147/PPA.S484632","DOIUrl":"10.2147/PPA.S484632","url":null,"abstract":"<p><strong>Purpose: </strong>Lower urinary tract symptoms (LUTS) consist of voiding and storage symptoms. While the therapeutic efficacy of current LUTS medications is limited, and with more than 20% of patients suffering from mixed symptoms, current guidelines offer nothing more than combining monotherapies. An individualized approach is urgently warranted, and phytomedicines have become an integral part of patient-empowerment in therapeutic shared-decision making processes. Therefore, we aimed to investigate patients' preference of phytomedicines and treatment adherence at the dawn of an era leaving α₁-blocker monotherapies behind.</p><p><strong>Patients and methods: </strong>A questionnaire was prepared, and patients at our tertiary referral center were given the opportunity to voluntarily participate in our survey. We collected questionnaires from 300 patients during their visits from January 2022 to December 2022.</p><p><strong>Results: </strong>With 73% (218/300), most of our study cohort had either taken one or more or were currently on prescription medication for LUTS/BPH. Patients were prescribed α₁-blockers (72%), followed by 5α-reductase inhibitors (21%), and phosphodiesterase-5-inhibitor (5%), while antimuscarinics and β₃-agonists were rarely prescribed. However, 41% (89/218) of our patients, who were taking medication for LUTS, had taken or were currently taking phytomedicines, making this the second most common drug class in our patient cohort. Patients scored the efficacy of phytomedicines at a mean in the lower third, but 87% of patients attributed excellent tolerability, and only 9% experienced side effects. While 43% of patients recommended phytomedicines for other patients, two-thirds of patients thought phytomedicines should be covered by statutory health insurance.</p><p><strong>Conclusion: </strong>We found that phytomedicines were the second most common drug class taken by LUTS patients at our hospital. Reasons may be easy availability as over the counter medication and a superior safety profile with less bothersome side effects than commonly prescribed drug classes. Taken together, phytomedicines may be able to bridge an important gap in LUTS pharmacotherapy to provide sufficient treatment adherence where prescription drug classes fail, and ultimately, adequate improvement of symptoms. However, patients need to be counseled on potentially limited efficacy.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2507-2518"},"PeriodicalIF":2.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Strategies for Enhancing Medication Adherence in the Kingdom of Saudi Arabia (KSA): A Cross-Sectional Study.","authors":"Farah Kais Alhomoud, Lama Wesam Alwohaibi, Kawthar Aljarrash, Faten Alhomoud, Khalid Alamer, Mohammed M Alsultan, Yousef Alqarni, Noor Alotaibi, Anwar Khalifah Alsaad, Afrah Dhafer Alqahtani, Reem Saad Alkhnbashi","doi":"10.2147/PPA.S499795","DOIUrl":"10.2147/PPA.S499795","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess medication adherence strategies among users in Saudi Arabia, explore the prevalence and effectiveness of behavioral, technical, and organizational tools, and identify key predictors of adherence related to demographic, health, and medication characteristics.</p><p><strong>Patients and methods: </strong>A descriptive cross-sectional study was conducted among 250 Saudi residents aged ≥18 who regularly take prescription/non-prescription medications. The questionnaire was developed through a literature review, validated by academic pharmacists, and refined based on pilot testing feedback. A convenience sampling method, complemented by snowball sampling, was employed to recruit participants. Limitations like sampling bias and self-reported data emphasize the need for broader studies. Quantitative analysis was performed using IBM SPSS.</p><p><strong>Results: </strong>Participants were predominantly young adults (84%) and females (84%), with 54% reporting being healthy and 46% managing chronic conditions. Behavioral strategies, such as time-based reminders, were the most commonly used (40%), followed by technical tools (33%), including mobile applications. Employment status significantly influenced adherence, with employed individuals (adjusted OR: 3.274, p = 0.028) and those working >8 hours daily (adjusted OR: 9.838, p = 0.049) exhibiting higher adherence. Fieldwork negatively impacted adherence (adjusted OR: 0.052, p = 0.007). While other demographic and health factors showed no significant associations, trends suggested that complex medication regimens increased the likelihood of using adherence strategies.</p><p><strong>Conclusion: </strong>Behavioral strategies, such as time- and location-based reminders, and technical tools, like apps, effectively improved medication adherence. Healthcare providers should promote simple, cost-effective methods, such as pillboxes and mobile reminders, tailored to patient needs. Addressing adherence barriers for individuals with demanding/unexpected schedules or complex regimens through targeted interventions and awareness campaigns is essential. Future research should explore these strategies' scalability and long-term impact in diverse healthcare settings.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2469-2480"},"PeriodicalIF":2.0,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstacles to Medication Adherence for Patients with Inflammatory Bowel Disease: A Qualitative Study in East China.","authors":"Fen Xu, Jingjing Xing, Mingna Fan, Zhiping Zhu, Yan Chen, Wen Hu, Yunxian Zhou","doi":"10.2147/PPA.S486974","DOIUrl":"10.2147/PPA.S486974","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the factors impacting medication non-adherence in patients with inflammatory bowel disease (IBD) in China, and to provide a reference for effective interventions.</p><p><strong>Patients and methods: </strong>Individual semi-structured interviews were conducted between December 2020 and July 2021 in four tertiary hospitals in East China. A conventional content analysis method was used in data analysis to extract themes and sub-themes in IBD Patients with poor medication adherence.</p><p><strong>Results: </strong>The 10 participants included were those who were diagnosed with IBD at least 1 year and could provide rich information and express strong desire. Seven themes emerged after data analysis: (a) non-acceptance of disease; (b) Lack of cognition of disease; (c) medication beliefs; (d) perceived efficacy; (e) Forgetting and delays; (f) costs of medication; (g) personality and psychological factors.</p><p><strong>Conclusion: </strong>Our data confirmed that in addition to comprehensive disease education and effective communication, medical staff should also pay attention to individualized factors, and develop effective response strategies for medication management support to reduce recurrence and control the disease.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2481-2494"},"PeriodicalIF":2.0,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients' Preferences for the Treatment of a Single Missing Tooth in China: A Discrete Choice Experiment.","authors":"Ming-Yu Zhao, Wen Zeng, Sze Ngai Chan, Jianhao Du, Naman Rao, Taoran Liu, Wai-Kit Ming","doi":"10.2147/PPA.S475061","DOIUrl":"10.2147/PPA.S475061","url":null,"abstract":"<p><strong>Purpose: </strong>The main treatment options offered to patients to choose from when restoring a single missing tooth include tooth-supported three-unit fixed partial dentures (FPDs) and implant-supported single crowns (ISCs). However, due to the heterogeneity of current studies, it is difficult to objectively compare these two treatment strategies. In this study, a discrete choice experiment (DCE) was used to quantify the preferences of individuals undergoing restoration treatment for single tooth loss.</p><p><strong>Patients and methods: </strong>The DCE questionnaire was disseminated in a \"snowball\" fashion, with data collected from participants aged 18-60. Five important attributes of treatment were selected: (1) treatment procedure, (2) treatment time, (3) cost, (4) five-year survival rate, and (5) five-year complication rate. A conditional logit model was employed to ascertain the direction of participants' preferences for specific attribute levels and to derive their willingness to pay (WTP) through the principle of marginal utility.</p><p><strong>Results: </strong>287 participants completed the questionnaire. The results of the questionnaire revealed that the five-year complication rate (42.42%) was the most important attribute, followed by cost (20.43%), five-year survival rate (14.23%), treatment time (13.44%), and treatment procedure (9.49%). Participants were willing to pay RMB$11076.2 (USD$1,772.2) to obtain a 10% extra reduction in the five-year complication rate, and RMB$7434.6 (USD$1,189.5) for a non-invasive treatment.</p><p><strong>Conclusion: </strong>In the ranking of the relative importance of key factors affecting single missing tooth restoration, complication rates are most highly valued, suggesting that reducing the complication rate is a key issue to be addressed in prosthodontics. In addition, deriving the ranking of patients' concerns about key factors can help to improve doctor-patient communication and provide a reference for treatment technology development and medical decision-making.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2455-2467"},"PeriodicalIF":2.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}