Patient preference and adherence最新文献

{"title":"Home-Based Self-Management After Permanent Pacemaker Implantation: What Should Patients Know.","authors":"Han Yan, Yu Shuang Chen, Yi Li, Guan-Xing Wei, Fang Ma, Qiu Lan Hu, Lan Ding, Wei Wei, Yan Li, Yang-Juan Bai","doi":"10.2147/PPA.S535177","DOIUrl":"10.2147/PPA.S535177","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study is to systematically explore and summarize the best evidence of home-based self-management in patients with permanent pacemaker implantation, providing comprehensive references and guidance for improving the self-management ability of such patients.</p><p><strong>Methods: </strong>Using the \"6S\" model, a systematic literature search was conducted on home-based self-management in patients with permanent pacemaker implantation. The types of literature included best practice, clinical decision-making, guidelines, expert consensus, systematic review and evidence summary. According to the inclusion and exclusion criteria, two researchers screened the literature, evaluated the quality, extracted the data, synthesized the evidence.</p><p><strong>Data sources: </strong>BMJ Best Practice, Up To Date, Joanna Briggs Institute (JBI), the World Health Organization (WHO), the Guidelines International Network (GIN), the National Institute for Health and Care Excellence (NICE), the Registered Nurses Association of Ontario (RNAO), the Scottish Intercollegiate Guidelines Network (SIGN), the American Heart Association (AHA), the Cochrane Library, PubMed, CINAHL, Web of Science, Medlive, CNKI Database, SinoMed (China Biomedical Literature Database), Wanfang Database and VIP Database. The retrieval period spanned from the establishment of these databases until January 31, 2025.</p><p><strong>Results: </strong>A total of 21 articles were included, 1 best practice, 9 clinical decision-making, 5 guidelines, 3 expert consensus, 1 systematic review, and 2 evidence summaries. Thirty-five pieces of the best evidence from 7 aspects were summarized, including complication management, electromagnetic interference management, sports rehabilitation management, operative limb management, postoperative follow-up management, role management, and emotional management.</p><p><strong>Conclusion: </strong>This review comprehensively summarized the best evidence home-based self-management in patients with permanent pacemaker implantation. These findings are scientific and referential, and provide evidence-based support for nursing and management of patients during home-based rehabilitation.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2771-2786"},"PeriodicalIF":2.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12430239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial Management Strategies for Oral Mucosal Lesions Among Local Pharmacists in Saudi Arabia: A Cross-Sectional Study.","authors":"Soulafa Almazrooa, Sarah AlFarabi Ali, Noor Hakem Alfaqiri, Khlood Mohammed Alghamdi, Nour Baghdadi, Hebah AlDehlawi, Sara Akeel","doi":"10.2147/PPA.S540449","DOIUrl":"10.2147/PPA.S540449","url":null,"abstract":"<p><strong>Purpose: </strong>Pharmacists may be an initial point-of-contact for patients with oral mucosal lesions. The purpose of this study was to investigate the proficiency of pharmacists in recognizing and managing oral mucosal lesions to help formulate educational recommendations for improvements in pharmacist-led patient care.</p><p><strong>Methods: </strong>Pharmacists in community pharmacies in Jeddah, Saudi Arabia, completed structured interviews that included five images of oral mucosal lesions (Herpes labialis, Lichen planus, Traumatic lip ulcer, Candidiasis, and Squamous cell carcinoma) with short clinical scenarios. Pharmacists were asked how they would manage the patients and about their knowledge of oral cancer.</p><p><strong>Results: </strong>One hundred and forty pharmacists participated. Herpes labialis was correctly identified by 81.6% of pharmacists, followed by traumatic ulcers (65.2%). No pharmacist correctly identified lichen planus, while squamous cell carcinoma was correctly identified in 14.9% of cases. Lichen planus (51.8%) was most commonly referred to specialist services, followed by squamous cell carcinoma (45.4%). Most pharmacists prescribed over-the-counter medications to treat the lesions. Most pharmacists recommended appropriate antiviral treatment for herpes labialis (70.2%) and wound care for traumatic lip ulcers (71.6%). However, 68.1% referred patients to healthcare professionals. Around 75.2% of pharmacists opted to refer to healthcare providers in cancer patients.</p><p><strong>Conclusion: </strong>While pharmacists could play a significant role in providing accurate and timely medical or pharmacological advice to patients with oral mucosal lesions, further education and training are required to improve knowledge to inform decision-making.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2787-2796"},"PeriodicalIF":2.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12430262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Early Symptom Experiences and Self-Management Strategies Among Postoperative Kidney Transplant Patients on Symptom Management Theory: A Qualitative Study.","authors":"Na Hu, Tiantian Chang, Delong Jiang","doi":"10.2147/PPA.S542956","DOIUrl":"10.2147/PPA.S542956","url":null,"abstract":"<p><strong>Background: </strong>After kidney transplantation, patients need to take immunosuppressants for life to maintain their kidney functions. However, patients still face various symptoms and reactions after the surgery, which poses great challenges to their kidney rehabilitation and public health management. This study is based on the symptom management theory and focuses on exploring the unique experiences of real symptom perception and symptom management coping strategies of kidney transplant patients in the early postoperative period.</p><p><strong>Methods: </strong>This study adopted the descriptive qualitative research method. From February to April in 2025, 13 patients who underwent kidney transplantation were recruited by purposive sampling in a tertiary hospital in Northeast China. Data collection was conducted through semi-structured one-on-one interviews, and the data were analyzed using content analysis method.</p><p><strong>Results: </strong>This study identified a total of 4 themes and 9 sub-themes, namely: (1) The diversity and complexity of symptom experiences (irregular dynamic changes, excessive symptom burden); (2) Coping strategies for symptom experiences (positive approach to challenges, negative responses to symptoms); (3) Adverse effects of symptoms (affecting personal values, family relationships, and social interactions); (4) Barriers to symptom management (internal and external factors).</p><p><strong>Conclusion: </strong>This study indicates that kidney transplant patients exhibit various symptoms and reactions in the early postoperative period and these reactions change irregularly. This also emphasizes the importance for clinical nursing researchers to dynamically assess the postoperative symptom reactions of kidney transplant patients. Based on the results of this study, clinical nurses can guide kidney transplant patients to adopt correct and positive coping strategies to manage their symptoms, establish an optimistic psychological state and perception of the disease, and by improving the internal and external influencing factors of symptom management, strengthen the relevant health education training for patients after surgery.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2759-2769"},"PeriodicalIF":2.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12428631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Medication Literacy and Its Determinants in Chinese Patients with Multimorbidity.","authors":"Xinyi Li, Changcheng Shi, Lihong Liu, Yibo Wu","doi":"10.2147/PPA.S539753","DOIUrl":"10.2147/PPA.S539753","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the medication literacy and influencing factors among patients with multimorbidity.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted to assess medication literacy using the medication literacy scale in patients with multimorbidity. Data were collected between June 20 and August 31, 2023, using stratified and quota sampling methods. The Wilcoxon tests or Kruskal-Wallis tests, Pearson's correlation analysis, and multiple stepwise linear regression were employed for the analysis.</p><p><strong>Results: </strong>3,955 patients with multimorbidity were included, with the average medication literacy score of 18.56±4.52 (scale range: 6-30). Younger age groups (18-30, 31-44, 45-59 years) had higher medication literacy than those aged 60 years or older (β = 0.11, 0.14, 0.17 respectively; all <i>P</i> <0.01). Higher education levels (middle/secondary degree, college/university degree, postgraduate degree) correlated with higher medication literacy compared to primary or lower education (β =0.21, 0.28, 0.13 respectively; all <i>P</i> <0.01). Currently married (β =0.09, <i>P</i> <0.01), unmarried (β =0.15, <i>P</i> < 0.01), and divorced individuals (β =0.06, <i>P</i> < 0.01) all exhibited higher medication literacy compared to widowed individuals. Compared with people living in Eastern China, those in Central/Western China (β =-0.06, -0.07, respectively; all <i>P</i> <0.01) had lower medication literacy. People whose area was urban (β =0.07, <i>P</i> <0.01) showed higher medication literacy compared with the rural. A higher score of depressive symptoms (β =-0.20, <i>P</i> <0.01) was negatively correlated with medication literacy, and a higher level of social support (β = 0.17, <i>P</i> <0.01) was positively correlated with medication literacy.</p><p><strong>Conclusion: </strong>It is critically important to improve medication literacy in patients with multimorbidity, particularly by optimizing medication instructions for understanding. Tailored interventions targeting older, less educated, rural, and central/western populations with emphasis on depression management and social support are needed.</p><p><strong>Study registration: </strong>ChiCTR2300072573.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2747-2757"},"PeriodicalIF":2.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12423441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home Rehabilitation Experience and Influencing Factors in Frail Elderly Patients with Lumbar Spine Surgery: A Qualitative Study.","authors":"Wei Jiang, Mingyang Qian, Qingsong Zou, Xiaowei Chen, Mengyi Xu, Jiangming Yu","doi":"10.2147/PPA.S531781","DOIUrl":"10.2147/PPA.S531781","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the home rehabilitation experience of frail elderly patients with lumbar spine surgery and to analyse potential factors promoting and hindering their rehabilitation.</p><p><strong>Methods: </strong>Purposive sampling method was used to select patients undergoing lumbar spine surgery in a tertiary general hospital in Shanghai, China, from January to March 2025 and 24 patients were chosen. A descriptive phenomenological research method was used with face-to-face semi-structured interview and raw data were analyzed using Colaizzi's seven-step method.</p><p><strong>Results: </strong>The transcripts were synthesized into three main themes and nine sub-themes. (1) Barriers to exercise compliance, including poor compliance with rehabilitation, frail state of the body, negative emotions, and lack of professional guidance. (2) Facilitating factors, including health literacy, family responsibility and social support. (3) Latent demands, including diversified information support needs and continuity of care needs.</p><p><strong>Conclusion: </strong>The home rehabilitation experience of frail patients was thoroughly explored, capturing physical, psychological, and rehabilitation needs. Future research should develop targeted home rehabilitation exercise programs for this vulnerable population and incorporate tele-rehabilitation modalities to facilitate safe and effective recovery at home.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2723-2735"},"PeriodicalIF":2.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Needs and Preferences of Patients with Port-Wine Stain and Associated Syndromes: A Qualitative Analysis of Social Media Discussions.","authors":"Yichen Liu, Xu Liu, Min-Kyu Kim, Beenu Maharjan, Xinjin Liu, Yuxin Duan, Dingling Li, Long Lin, Jingyuan Zeng, Hanfei Qin, Yifei Cheng, Linghong Guo, Xian Jiang","doi":"10.2147/PPA.S541439","DOIUrl":"10.2147/PPA.S541439","url":null,"abstract":"<p><strong>Purpose: </strong>Patients with port-wine stain (PWS) and related syndromes often face multifaceted challenges in disease management, including prolonged treatment cycles, appearance-related distress, and psychological burdens. Social media has become an important platform for these individuals to obtain information and share experiences. However, there is a lack of systematic qualitative research exploring their genuine needs. This study analyzes content from social media to identify patients' core concerns during the diagnostic and therapeutic process, providing both theoretical foundations and practical references for developing patient-centered care models.</p><p><strong>Methods: </strong>This study systematically analyzed PWS-related posts published between 2010 and 2023 across open social media platforms including Twitter, Facebook, and Baidu. A stratified sampling method was applied, and natural language processing was used to extract keywords and thematic sentences. Through expert review and AI-assisted classification, core patient needs in disease management were qualitatively summarized and categorized.</p><p><strong>Results: </strong>A total of 1528 social media posts were analyzed, yielding 4,190 extracted keywords categorized into six major themes. Treatment-related concerns were the most prominent (30.04%), particularly focusing on treatment choices, side effects, and delayed efficacy. Diagnostic confusion was also frequently mentioned (24.41%). A significant number of posts conveyed emotional distress and a strong desire for shared experiences, with emotional support themes accounting for 4.19%, highlighting their importance. Some patients proactively shared treatment journeys, contributing to a supportive and empathetic community atmosphere.</p><p><strong>Conclusion: </strong>This study distilled key needs from authentic patient expressions and found that beyond clinical diagnosis and treatment, PWS patients also highly value emotional support and anxiety relief regarding relapse. These findings underscore the necessity of building patient-centered care systems that integrate emotional and psychological support while managing treatment expectations. Future studies should combine quantitative research and clinical data to refine variable analyses and develop educational and intervention strategies tailored to real online patient needs.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2737-2746"},"PeriodicalIF":2.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental Perspectives on Childhood Vaccination: Analysing Knowledge and Attitudes Among Families in Tabuk, Saudi Arabia.","authors":"Faten Ezzelarab Younis, Omnia S Elseifi, Fatma Mustafa Toonisi, Maram Abdullah Alsamti, Hala Turki Alanazi, Eman M Mortada","doi":"10.2147/PPA.S537453","DOIUrl":"10.2147/PPA.S537453","url":null,"abstract":"<p><strong>Purpose: </strong>To ascertain the knowledge and attitudes of parents on childhood vaccination in Tabuk, Saudi Arabia, as well as their perceived barriers to vaccination.</p><p><strong>Patients and methods: </strong>Three hundred and thirty parents were selected in this cross-sectional study by convenience sampling from the parents who attended several primary healthcare facilities to vaccinate their children. A pre-made questionnaire was used, which included the sociodemographic characteristics and questions about the parents' knowledge, attitude toward childhood vaccination, and compliance with vaccination according to the immunization schedule. The associations between the research variables were evaluated using chi-square, the Pearson correlation, and multiple binary logistic regression.</p><p><strong>Results: </strong>Among the parents studied, 66.1% had adequate knowledge of childhood vaccination, and 55.5% held positive attitudes toward it. The significant associated factors for adequate knowledge and positive attitude were the age from 30 to <40 (OR: 2.6 and 2.3, P<0.05), increasing education level (OR: 2.1 and 1.7, P<0.05), and work related to the health sector (OR: 2.7 and 4.4, P<0.05). The examined parents' attitude score increased significantly with the high level of knowledge score (r = 0.603, P < 0.001). Among the parents studied, 62.9% adhered to the childhood immunization schedule. In contrast, the most common perceived barriers for those who did not comply were the illness of a family member (36.7%), the child's sickness (32.8%), or being busy on vaccination day (31.4%).</p><p><strong>Conclusion: </strong>Around half of the parents in this study had a positive attitude and understood the significance of vaccination. Nevertheless, the contributory factors of insufficient knowledge and attitude, like lower levels of education and advanced age, should be handled through health education initiatives to raise their awareness and motivate them to complete their children's vaccination.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2711-2721"},"PeriodicalIF":2.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial.","authors":"Berta Munné-Barellas, Ramon Monfà, Carl Llor, Ana Garcia-Sangenís, Cristina Miranda-Jiménez, Rosa Morros, Ana Moragas, Pablo Alvarez-Greciano, Alfonso Leiva, Mª Luisa Lozano-Del Hoyo, Maria Antonia Sánchez-Calavera, Jaime Marín-Cañada, Raquel Sánchez-Ruano","doi":"10.2147/PPA.S531582","DOIUrl":"10.2147/PPA.S531582","url":null,"abstract":"<p><strong>Background: </strong>This paper focuses on women's subjective experiences with UTIs and antibiotic use. Uncomplicated urinary tract infections (UTI) are among the most common infections treated in primary care, however, there is limited evidence regarding the experiences and their antibiotic treatment preferences.</p><p><strong>Objective: </strong>The aim of this study is to gather experiences, beliefs, and attitudes regarding the use of antibiotics and the participation in the clinical trial.</p><p><strong>Methods: </strong>This qualitative sub-study is part of the SCOUT project, which, through a clinical trial, aims to assess the effectiveness of four short antibiotic regimens (a single 3g dose of fosfomycin; 3g of fosfomycin for two days; 400mg of pivmecillinam for three days; and 100mg of nitrofurantoin for five days). A total of 68 semi-structured interviews were conducted in four regions of Spain (Catalonia N=19, Aragón N=19, Madrid N=15, and the Balearic Islands N=15). A purposive and theoretical sampling approach was employed. Participants were recruited after taking part in the clinical trial. Data collection took place between March and July 2024 and analysed using Thematic Analysis.</p><p><strong>Results: </strong>UTI did not cause excessive concern, except in cases where the antibiotic was ineffective or when participants had experienced multiple infections in the past. Fosfomycin was the most widely recognized antibiotic, and the two-dose regimen was generally well-regarded for being easy to take while also being more effective than the single-dose treatment. Longer regimens could cause some side effects, but in certain cases, they were perceived as more effective. Participation in the clinical trial was viewed positively, as it contributed to increasing overall knowledge about UTI and the antibiotics used to treat them, as well as ensuring closer monitoring of each specific case.</p><p><strong>Conclusion: </strong>This study gathers experiences related to UTI, antibiotic treatment regimens, and participation in the SCOUT clinical trial. It highlights the need to document the realities of UTI in order to improve future clinical trials.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2673-2685"},"PeriodicalIF":2.0,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Stigma Among Women with Infertility: A Cross-Sectional Study in Shenzhen, China.","authors":"Juanhua Li, Xiaoxuan Chen, Chi-Zhi Wang, Yangliu Ye, Xiaofei Tian, Ling-Ling Gao","doi":"10.2147/PPA.S541661","DOIUrl":"10.2147/PPA.S541661","url":null,"abstract":"<p><strong>Purpose: </strong>The issue of infertility is a worldwide challenge, estimated to affect approximately 50 million couples. Infertility is a stressful event for women and may result in stigma. This study aimed to investigate stigma and its predictors in Chinese women with infertility.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted in Shenzhen, China, from November 2022 to April 2023. Two hundred seventy-five women with infertility completed the Mandarin version of the Infertility Stigma Scale (ISS), the Mandarin version of the Fertility Problem Inventory (M-FPI), and a socialdemographic data sheet. Descriptive statistics were used for demographic and infertility-related characteristics and study variables. The predictors of stigma were subjected to univariate and multivariate analyses.</p><p><strong>Results: </strong>Although the women with infertility had an average mild level of stigma (54.00 [38.00, 68.00]), 26.9% (n = 74) and 4.7% (n = 13) of the women had a moderate and severe level of stigma, respectively. The women had an average moderate level of infertility-related stress (143.00 [122.00, 157.00]), with 7.3% (n = 20) of women having severe infertility-related stress. The predictors of stigma in women with infertility were the dimensions of social concern, relationship concern, and need for parenthood of infertility-related stress.</p><p><strong>Conclusion: </strong>This study found that stigma and infertility-related stress were prevalent in Chinese women with infertility. Psychosocial strategies aimed at reducing infertility-related stress may help mitigate perceived stigma in this population.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2687-2696"},"PeriodicalIF":2.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to Opioids for Cancer-Related Pain Among Patients with Cancer in a Resource-Restricted Hospital in Palestine.","authors":"Nancy Yacoub Nashwan, Noraida Mohamed Shah, Farida Islahudin, Sameh Mohammed Wasfi Iii","doi":"10.2147/PPA.S525593","DOIUrl":"10.2147/PPA.S525593","url":null,"abstract":"<p><strong>Purpose: </strong>Cancer-related pain is a critical symptom that significantly impacts patients' quality of life. This study aimed to assess adherence and identify factors influencing adherence to opioid analgesics for cancer-related pain among cancer patients at a hospital setting in Gaza, Palestine.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted from December 2021 to March 2022, involving cancer patients receiving opioid for cancer-related pain. Participants completed a set of questionnaires on socioeconomic data, pain intensity and interference using the Brief Pain Inventory (BPI), adherence to opioids using the General Medication Adherence Scale (GMAS), and beliefs about pain and opioids using the Pain and Opioid Analgesic Beliefs-Cancer (POASB-CA) scale. Patients' clinical data were collected from the patients' medical records. Simple and multiple linear regression analyses were utilized to elucidate factors associated with adherence towards opioids for cancer-related pain.</p><p><strong>Results: </strong>A total of 270 patients were recruited. Most patients (88.5%) were at least partially adherent to the opioid analgesic. The average pain intensity score was 5.796 (SD = 1.98), and pain interference scored 7.093 (SD = 3.63). Simple linear regression identified the following parameters to be significantly associated with adherence: education level, presence of comorbidity, average percentage of pain relief experienced over the past 24 hours, negative effect beliefs and pain endurance beliefs. Based on multiple linear regression analysis, education level, percentage of pain relief and presence of side effects were positive predictors of higher adherence score (B=1.082, CI 0.139 to 2.025, p=0.025; B=0.076, CI 0.046 to 0.105, p<0.001 and B=1.578, CI 0.116 to 3.041, p=0.034, respectively).</p><p><strong>Conclusion: </strong>Adherence to opioids for cancer-related pain was generally good. Influencing factors included education level, average pain relief in the past 24 hours, and opioid side effects. These results highlight the complex nature of adherence in managing cancer pain and suggest areas for targeted interventions.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"19 ","pages":"2663-2671"},"PeriodicalIF":2.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}