Patient preference and adherence最新文献

{"title":"The Attitudes Toward Polypharmacy and Willingness to Deprescribe Among Patients with Multimorbidity in Rural Areas of Shandong Province in China: A Cross-Sectional Study.","authors":"Xi Liu, Yang Zhao, Tianya Da, Shilong Zhang, Haipeng Wang, Hui Li","doi":"10.2147/PPA.S498472","DOIUrl":"10.2147/PPA.S498472","url":null,"abstract":"<p><strong>Purpose: </strong>Multimorbidity and polypharmacy have emerged as significant global issues, heightening the risks of potentially inappropriate medications (PIMs). This necessitates medication optimization through deprescribing. Understanding patients' decision-making preferences regarding medication cessation is crucial for mitigating medication-related risks. This study aims to capture the attitude of patients with multimorbidity towards deprescribing in rural China and to ascertain whether individual characteristics were linked to these attitudes.</p><p><strong>Patient and methods: </strong>A cross-sectional study employing the validated Patients' Attitudes Towards Deprescribing (PATD) questionnaire was performed in rural regions of Eastern China. The PATD Questionnaire was utilized to investigate patients' attitudes towards the concurrent use of multiple medications, with response elicited on a 5-point Likert scale. Utilizing multistage random sampling, a total of 560 participants with multimorbidity were randomly selected from two counties in Shandong Province. Descriptive statistics were reported on participant characteristics. Binary logistic regression analysis was conducted to identify the factors that influenced participants' willingness to discontinue or reduce their medication.</p><p><strong>Results: </strong>The median age of patients was 69.5 years (SD=8.2 years), and 314 were female. Nearly one in four patients experienced polypharmacy, while 42.2% had two chronic diseases. More than half of the participants (55.2%) reported that they would be willing to stop one or more medications if their physicians agreed, and 52.9% of participants agreed to reduce the medications taken. Participants with two chronic conditions (OR=3.038, 95% CI=1.342-6.881), taking less than 10 tablets (OR=2.994, 95% CI=1.113-8.054), having their own source of healthcare expenditure (OR=0.639, 95% CI=0.432-0.945), and hospitalization in the prior year (OR=0.636, 95% CI=0.429-0.944) were significantly associated with patients' attitudes toward deprescribing.</p><p><strong>Conclusion: </strong>Over half of patients with multimorbidity expressed a willingness to have one or more of their medicines deprescribed. Physicians can be trained in the integrated care of chronic diseases and encouraged to engage in discussions about deprescribing with patients having multimorbidity and polypharmacy during their routine practice.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2637-2646"},"PeriodicalIF":2.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11681821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confirmatory Factor Analysis of the Malay Version of the Malaysia Medication Adherence Assessment Tool (MyMAAT) Among Patients with Chronic Medications.","authors":"Gaik Tian Ong, Sarimah Abdullah, Norsa'adah Binti Bachok","doi":"10.2147/PPA.S475738","DOIUrl":"10.2147/PPA.S475738","url":null,"abstract":"<p><strong>Purpose: </strong>The bilingual Malaysia Medication Adherence Assessment Tool (MyMAAT) was developed using the Exploratory Factor Analysis (EFA) and the current study intended to confirm the measurement model, dimensionality and ensure the factor structure by the Confirmatory Factor Analysis (CFA). The objective of this study was to validate the Malay version of the MyMAAT in measuring medication adherence among participants with chronic medications.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted using a self-report questionnaire at five health clinics and a hospital in Kuala Lumpur and Putrajaya region between May to November 2023. The participants were selected using quota sampling and written informed consent was obtained from each participant prior to data collection. There are two constructs in the MyMAAT, namely the Specific Medication-Taking Behaviour (Factor 1) and the Social-Cognitive Theory of Self-Efficacy and Social Support (Factor 2).</p><p><strong>Results: </strong>Four hundred and seventy participants participated in the CFA study. The final model for the Malay version of the MyMAAT retained the two constructs and 12 items with good fit: CFI = 0.978, TLI = 0.973, RMSEA = 0.036 (90% CI 0.001,0.067) and with good composite reliability CR 0.790 for Factor 1 and 0.787 for Factor 2. The factor loadings ranged from 0.413 to 0.832 with <i>p</i>-value < 0.001. The AVE for Factor 1 was 0.664 and for Factor 2 was 0.491. There was a strong correlation (<i>ρ</i> = 0.507, <i>p</i> < 0.001) between the Malay version of the MyMAAT and the Malay version of the MMAS-8 by adherence category from the data of 191 participants. Twenty-six participants completed the test-retest after five to ten days from the first administration. The Malay version of the MyMAAT showed moderate to excellent with ICC 0.932 (95% CI: 0.661,0.986) for Factor 1 and poor to excellent for with ICC 0.956 (95% CI:0.325,0.997) for Factor 2 by using the Two-Way Mixed Model and Consistency type.</p><p><strong>Conclusion: </strong>It is concluded that the Malay version of the MyMAAT is valid and reliable in measuring medication adherence among patients with chronic medications.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2609-2620"},"PeriodicalIF":2.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11669339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness, Beliefs, and Psychological Impact of Patients with Alopecia Areata in Saudi Arabia: A Multi-Center Study.","authors":"Nasser Abdullah Almulhim, Heba Yousef Alojail, Mohammed Abdullah Aljughayman, Fatimah Hussain Almarri, Norah Hamad Alsultan, Latifah Adel Albash, Sara Khalid Almukhaimar, Ali Abduljalil Alkhamis, Mohammed Abdullah Albaqshi, Amnah Ali Alkhawajah","doi":"10.2147/PPA.S486039","DOIUrl":"10.2147/PPA.S486039","url":null,"abstract":"<p><strong>Purpose: </strong>Alopecia Areata (AA) is a complex autoimmune condition characterized by long-term inflammatory non-scarring patches of hair loss on the face, scalp, and body. Its development involves a combination of genetic, immunological, and environmental factors, making it challenging to understand and treat. This study aims to assess the awareness, beliefs, and psychological impact of patients with Alopecia Areata.</p><p><strong>Patients and methods: </strong>This cross-sectional study was conducted in Eastern and Central provinces of Saudi Arabia and utilized online questionnaires to evaluate knowledge, beliefs, and psychological effects of patients with Alopecia Areata. These questionnaires were distributed using social media platforms.</p><p><strong>Results: </strong>This study enrolled 248 patients with Alopecia Areata (AA), of whom 38.7% were aged 31-40 years and 55.2% were males. The majority were Saudis (98.4%), married (54%), and residing in the Central Region (60.1%). Nearly half (48.8%) were employed in non-medical fields, and 30.6% were vocational school graduates. Healthcare providers were the main source of AA information (52.8%), with most patients aware of AA's seriousness, curability, and quality of life impact, though many had low knowledge and experienced negative psychological effects such as shyness, anxiety, and depression.</p><p><strong>Conclusion: </strong>Despite low self-rated knowledge, most patients recognized AA as serious and requiring treatment. Psychological well-being was heavily impacted by AA severity, quality of life, disease duration, and treatment efficacy. Although many patients showed improved AA status and good medication compliance, adverse psychological effects persisted, highlighting the need for larger studies to better understand and address these issues.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2597-2607"},"PeriodicalIF":2.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11668324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Adherence of Young Male Patients with HBV Infection to the Regular Follow-Up via Mobile Healthcare Platform Might Be Cost-Effective to Decrease the Morbidity of Advanced Liver Cancer.","authors":"Hao Liang, Min Yang, Dan Luo, Ya-Kun Wu","doi":"10.2147/PPA.S497831","DOIUrl":"10.2147/PPA.S497831","url":null,"abstract":"<p><strong>Background: </strong>Young adults contribute substantially to the social economy. However, the number of young adults with liver cancer has increased recently. In addition, the mortality rate of these patients is high.</p><p><strong>Methods: </strong>This retrospective study investigated the risk factors of young patients diagnosed with liver cancer over the past 12 years.</p><p><strong>Results: </strong>The risk factors of liver cancer, including male, HBV infection, and family history of diseases, were more common in young patients. Nearly 80% of young patients (198/253) were tested as positive HBsAg. However, most of these patients did not visit doctors regularly, as recommended. Thus, 55.7% of young patients were diagnosed with advanced liver cancer. The aspartate aminotransferase (AST) levels were independently associated with advanced liver cancer (OR = 4.262, 95% CI = 1.559-11.65, P = 0.005) in the multivariable logistic regression. The 1-year survival rate of these patients was 19.4%.</p><p><strong>Conclusion: </strong>The high-risk factors of liver cancer are common in young patients. The poor adherence to regularly visited doctors in young patients might contribute to the high ratio of advanced liver cancer. The 1-year survival rate of these patients is low. Improving patient's adherence via mobile healthcare platform and monitoring serum AST levels might decrease the incidence and mortality of liver cancer in young adults.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2581-2595"},"PeriodicalIF":2.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11665142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Proton-Pump Inhibitor Adherence Intervention Between Primary Care and Community Pharmacies: A Pre-Post Intervention Study.","authors":"María Puig-Moltó, Blanca Lumbreras, Elsa López-Pintor","doi":"10.2147/PPA.S485307","DOIUrl":"10.2147/PPA.S485307","url":null,"abstract":"<p><strong>Purpose: </strong>Proton-pump inhibitor (PPI) therapy stands as the primary treatment for upper gastrointestinal symptoms, yet poor adherence often results in treatment failure. Given that patients experiencing these symptoms frequently seek assistance at community pharmacies, the development of collaborative tools with primary care is becoming imperative. The objective was to assess the effectiveness of a pharmaceutical intervention, as demonstrated by a collaborative model between primary care and community pharmacies, in enhancing adherence to PPI among patients experiencing upper gastrointestinal symptoms.</p><p><strong>Patients and methods: </strong>A Pre-post intervention study was carried out in Spanish community pharmacies (June-October 2022). During the baseline visit, patients' sociodemographic and clinical variables were evaluated. Patients were categorized as adherent or non-adherent using the Morisky Medication Adherence Scale (MMAS-4). In the follow-up visit (14 days later), the impact of the intervention was measured by changes in the Gastroesophageal Reflux Disease Impact Scale (GIS).</p><p><strong>Results: </strong>Of the 351 patients with an active PPI prescription, 178 (50.7%) were non-adherent. Nearly 70% of these patients (122, 68.5%) received an intervention to improve adherence. The overall GIS score improved after the intervention (mean 25.34, SD 5.66 vs mean 27.64, SD 5.63, p < 0.001). All GIS score items showed improvement after the intervention except for the item regarding the taking of additional medication different from that prescribed by the clinician (p = 0.200).</p><p><strong>Conclusion: </strong>The pharmaceutical intervention had a positive impact on patients' symptom relief and overall quality of life, highlighting the significance and efficacy of a collaborative model between primary care and professional pharmaceutical services.</p><p><strong>Clinical trials registry: </strong>Clinical Trial Registration (NCT05162079).</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2569-2580"},"PeriodicalIF":2.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors to Poor Quality of Life Among Patients with Heart Failure and Its Correlation with Their Medication Adherence: Finding for Healthcare Improvement and Follow-Up.","authors":"Sameer A Alkubati, Homoud Khaled Aleyadah, Mohammad Alboliteeh, Abdulhafith Alharbi, Bandar Alsaif, Bushra Alshammari, Anas Balawi","doi":"10.2147/PPA.S503087","DOIUrl":"10.2147/PPA.S503087","url":null,"abstract":"<p><strong>Background: </strong>Understanding medication adherence and its relationship with quality of life (QoL) is essential for improving health outcomes in patients with heart failure (HF).</p><p><strong>Objective: </strong>This study aimed to investigate the predictors of poor quality of life and its relationship with medication adherence among patients with heart failure.</p><p><strong>Methods: </strong>A cross-sectional correlational study was performed on 229 patients with HF receiving care at the Cardiac Center of King Salman Specialist Hospital from March to June 2024. Data were collected using a structured questionnaire comprising patient demographics, the Minnesota Living with Heart Failure Questionnaire (MLHFQ) to assess QoL, and the General Medication Adherence Scale (GMAS) to measure medication adherence.</p><p><strong>Results: </strong>The mean medication adherence score among patients with heart HF was 17.53 ± 6.94. The level of adherence was moderate among most patients (47.2%), high (29.7%), and poor (23.1%). Regarding QoL, the mean total score for overall QoL was 42.16 ± 20.53. Specifically, the mean scores were 15.24 ± 8.65 and 10.53 ± 5.82 for the physical and emotional dimensions of QoL, respectively. More than half of the patients experienced poor QoL, while moderate QoL was observed in 31.9% and good QoL in 17% of patients. Furthermore, there were moderate negative correlations between medication adherence and physical QoL (r= -0.51), emotional QoL (r = -0.59), and overall QoL (r = -0.59), all of which were statistically significant (p <0.001).</p><p><strong>Conclusion: </strong>Moderate-to-poor levels of medication adherence and QoL were found among HF patients receiving care in Hail City. Therefore, interventions to improve medication adherence among patients with HF must be prioritized to enhance health outcomes and QoL. It is also crucial to address the factors that negatively influence medication adherence to overcome the barriers that hinder optimal medication adherence.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2545-2557"},"PeriodicalIF":2.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapy-Related Symptoms and Sense of Coherence: The Mediating Role of Social Support and Hope in Lung Cancer Patients Undergoing Chemotherapy.","authors":"Fang Wang, Anliu Nie, Shaona Liao, Zhisheng Zhang, Xiangfen Su","doi":"10.2147/PPA.S480306","DOIUrl":"10.2147/PPA.S480306","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the current status of the sense of coherence in lung cancer patients undergoing chemotherapy and explore the mediating role of social support and hope in the relationship between therapy-related symptoms and sense of coherence.</p><p><strong>Methods: </strong>We conducted a cross-sectional study to investigate lung cancer chemotherapy patients aged 18 years or older who completed at least two cycles of chemotherapy. Patients were recruited from the First Affiliated Hospital of Guangzhou Medical University's chemotherapy day ward from May to December 2023. Patients were required to complete a questionnaire that included the Sense of Coherence Scale, the Perceived Social Support Scale, the Herth Hope Index, and the Therapy-related Symptoms Checklist. The structural equation model was used to test the mediating role of social support and hope between therapy-related symptoms and the sense of coherence.</p><p><strong>Results: </strong>A total of 241 patients were included. The scores of the sense of coherence, hope level, therapy-related symptoms, and social support were 68.79 ± 11.24, 38.94 ± 4.25, 11.53 ± 8.15, and 69.49 ± 8.15, respectively. Sense of coherence, social support, hope, and therapy-related symptoms were significantly related (P<0.01). Therapy-related symptoms had a direct negative influence on the sense of coherence [B=-0.144, 95% CI (-0.209, -0.070)]. Meanwhile, therapy-related symptoms influenced the sense of coherence via three pathways: independent mediation of social support [B=-0.021, 95% CI (-0.065, -0.002)], independent mediation of hope [B=-0.022, 95% CI (-0.057, -0.000)], and chain mediation of social support and hope [B=-0.012, 95% CI (-0.035, -0.002)].</p><p><strong>Conclusion: </strong>Lung cancer patients undergoing chemotherapy experience a medium sense of coherence. This study's findings indicate that the relationship between therapy-related symptoms and sense of coherence is affected by the independent mediating effect of social support and hope and the chain mediating effect of social support and hope. Therefore, reducing the burden of their therapy-related symptoms, providing them with social support, and fostering their hope can enhance patients' sense of coherence and improve their quality of life.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2559-2568"},"PeriodicalIF":2.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Patient Satisfaction Attaining Primary Health Care Services at Health Centers in Mogadishu, Somalia.","authors":"Hassan Ali Abdi, Mohamed Omar Warsame, Mohamud Abdinor Adan, Mohamed Ahmed Hassan","doi":"10.2147/PPA.S486919","DOIUrl":"10.2147/PPA.S486919","url":null,"abstract":"<p><strong>Background: </strong>Patient satisfaction in healthcare a crucial aspect of quality assessment, especially in resource-limited settings like Mogadishu, Somalia, where challenges in service quality persist due to socioeconomic and infrastructural constraints. It plays a significant role in evaluating the overall healthcare experience and provides valuable insights into healthcare system strengths and weaknesses.</p><p><strong>Objective: </strong>This study aimed to assess patient satisfaction in primary health care facilities in Mogadishu to identify areas for improvement.</p><p><strong>Methodology: </strong>A facility-based cross-sectional survey of 358 patients was conducted from August 2023 to November 2023; Data was collected through questionnaires and analyzed using SPSS software. Quantitative data was analyzed using appropriate statistical methods, such as descriptive statistics and chi-square tests, to examine the relationships between patient satisfaction and various factors the statistical significance was declared at p-value < 0.05. Ethical approval was obtained from the Ministry of health Somalia before data collection permission was also obtained from the health facility in charges.</p><p><strong>Results: </strong>While a majority of respondents, 71.5% express overall satisfaction with the healthcare services provided, there were significant concerns regarding empathy, privacy, facility cleanliness, and waiting times. There is a statistically significant association between patients' visit frequency and their perceptions of various healthcare aspects. Patients who visited the healthcare facility 2-4 times expressed significantly more positive perceptions of healthcare providers' competence (p < 0.020), empathy (p < 0.009), time spent (p < 0.001), pharmacy services (p < 0.001), and facility cleanliness (p < 0.001) when compared to those with first-time visits or more frequent visits.</p><p><strong>Conclusion: </strong>The study highlights the importance of addressing communication gaps, enhancing facility hygiene, and reducing waiting times to improve patient satisfaction. To enhance patient satisfaction and overall healthcare quality, recommendations include healthcare provider training, facility hygiene upgrades, and the implementation of strengthened privacy protocols in Mogadishu's primary healthcare facilities.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2529-2543"},"PeriodicalIF":2.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with the Public's Intention to Report Adverse Drug Reactions to Community Pharmacists in the Makkah Region of Saudi Arabia: An Application of the Theory of Planned Behavior.","authors":"Fahad T Alsulami","doi":"10.2147/PPA.S495487","DOIUrl":"10.2147/PPA.S495487","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the public's intention to report ADRs to community pharmacists in the Makkah region of Saudi Arabia and to identify the factors influencing this intention, using the TPB as the theoretical framework.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in the Makkah region of Saudi Arabia via a nonprobability sampling method. Data were gathered through an online self-report survey designed to assess the public's intention to report ADRs to community pharmacists. Multivariate logistic regression analysis was used to examine the influence of three constructs of the TPB on this intention.</p><p><strong>Results: </strong>A total of 452 individuals participated in the study. Approximately 22% of them reported experiencing ADRs in the last six months, but only 21% were aware of the Saudi NPC. Approximately 62% of the participants expressed a strong intention to report ADRs to community pharmacists. The public exhibited a highly positive attitude toward reporting ADRs, alongside high subjective norms and perceived behavioral control. Among the TPB constructs, attitude had the most significant influence on the intention to report ADRs to community pharmacists, followed by subjective norms and perceived behavioral control.</p><p><strong>Conclusion: </strong>This study revealed a strong public intention to report ADRs to community pharmacists in the Makkah region, driven primarily by positive attitudes, supportive subjective norms, and high perceived behavioral control. However, the findings highlight a critical gap in public awareness of the Saudi NPC, with only 21% of participants aware of its existence. These results underscore the importance of targeted initiatives to improve awareness of the Saudi NPC and to leverage positive attitudes and social norms to promote ADR reporting practices effectively.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2495-2506"},"PeriodicalIF":2.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicine Usage for Hypertension Management in Type 2 Diabetes Patients in the Rural-Urban Fringe Zone, Suzhou City, Jiangsu Province, China.","authors":"Liping Wang, Jin Yan, Fenghua Wang, Peng Xue, Zheng Li, Rong Jiang, Min Lu, Ning Yang, Junli Wei, Maoti Wei, Zhimin Ma","doi":"10.2147/PPA.S475936","DOIUrl":"10.2147/PPA.S475936","url":null,"abstract":"<p><strong>Objective: </strong>Medicine is critical for blood-pressure control in patients with type 2 diabetes mellitus (T2DM), for evaluation of treatment patterns and effects would offer baselines for future health services.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from August 2018 to January 2021 in the urban-rural fringe zone of Suzhou City, Jiangsu Province, China. Blood pressure and antihypertensive medication use were collected from T2DM patients combined with hypertension (HTN). Using systolic blood pressure (SBP) and diastolic blood pressure (DBP) <140/85 mmHg as HTN controls, medicine usage patterns were analyzed.</p><p><strong>Results: </strong>Among the 931 T2DM patients with HTN, 333 (37.0%, 95% <i>CI</i>: 33.8%-40.2%) had HTN controlled with SBP and DBP of <140/85 mmHg. Partial following the medicine recommendations for HTN control were observed in this zone, and calcium channel blocker (CCB), angiotensin II receptor blocker (ARB), diuretics and β-receptor blocker (Βeta-blocker) were the most frequently used ones, especially for CCB and ARB, which accounted for 67% (625/931) and 55% (509/931), respectively. For combination usage, complete adherence to the recommendation was observed, ie, ARB + CCB and ARB + diuretics were listed as the top two, accounting 30% (282/931) and 16% (153/931), respectively. Combination therapies had HTN control rates ranging from 31.1% to 39.1%, lower than those of monotherapy (>40%). In monotherapies, CCB had control rate of 41.2% (115/279, 95% <i>CI</i> 35.4%-47.2%), higher than combination (31.9%, 105/329, 95% <i>CI</i> 26.9%-37.3%), as well as ARB; the single reagent had control rate of 42.0% (95% <i>CI</i> 33.7%-50.7%), higher than combination (32.2%, 95% <i>CI</i> 27.4%-37.3%).</p><p><strong>Conclusions: </strong>More than 60% of T2DM patients had blood-pressures above the target level and the pattern of medications for HTN control in T2DM patients followed the recommendation of the authorities; however, the effects were not as expected, and more antihypertensive medicines or combinations would not raise the HTN control rate.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"2519-2528"},"PeriodicalIF":2.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}