Kristine Harrsen, Murat Yildirim, Clodagh Beckham, Soma Nag, Xavier Guillaume, Amal Sadou, Arun Micheelsen, Stephan Heres, Sofia Pappa
{"title":"A Quantitative Discrete Choice Experiment Survey-Based Study of Preferences for a Hypothetical Long-Acting Injectable Antipsychotic Administered Once Every 2 Months Among People Living with Schizophrenia.","authors":"Kristine Harrsen, Murat Yildirim, Clodagh Beckham, Soma Nag, Xavier Guillaume, Amal Sadou, Arun Micheelsen, Stephan Heres, Sofia Pappa","doi":"10.2147/PPA.S622291","DOIUrl":"10.2147/PPA.S622291","url":null,"abstract":"<p><strong>Objectives: </strong>This quantitative preference study aimed to quantify the strength of preferences for a hypothetical once-every-2-months long-acting injectable (LAI) vs an oral medication or once-monthly LAI, to identify the factors that drive preference for a once-every-2-months LAI and to evaluate these preferences in relation to the current treatment in schizophrenia.</p><p><strong>Methods: </strong>An online survey that included a discrete choice experiment (DCE) component was used to quantify the preferences of adults living with schizophrenia who were receiving treatment with an oral antipsychotic or a once-monthly LAI from five countries across North America and Europe. The survey included questions about the respondent and their attitudes towards schizophrenia and treatment, including their views on a hypothetical LAI taken once every 2 months. The DCE component was used to determine preference weights for levels of the following treatment attributes: mode and frequency of administration, flexibility of administration, psychiatric hospital admission, symptom improvement, social functioning, feelings of sedation, and overall weight gain.</p><p><strong>Results: </strong>In total, 212 people living with schizophrenia completed the survey, of whom 66.5% were \"very satisfied\" or \"satisfied\" with their current treatment. A greater proportion of people living with schizophrenia currently receiving a once-monthly LAI (67.0%) were \"very likely\" or \"likely\" to try a hypothetical once-every-2-months LAI than those receiving oral treatment (46.2%). The most common motivation for trying a hypothetical once-every-2-months LAI was to not have to think of taking the medicine as often (43.6%), while the most common barrier was a fear of needles (30.4%). Results from the DCE indicated that symptomatic improvement and a reduced risk of hospital admission were among most important treatment attributes for acceptance.</p><p><strong>Conclusions: </strong>Most people living with schizophrenia were open to the idea of trying a hypothetical once-every-2-months LAI treatment for schizophrenia, particularly those who were currently receiving a once-monthly LAI.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"622291"},"PeriodicalIF":2.6,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13644573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Home Nutrition Management Experiences in Postoperative Esophageal Cancer Patients and Their Caregivers: A Study Utilizing Patient Journey Mapping.","authors":"Luman Zhang, Wenfeng Tang, Siqi Yang, Luying Zhou, Wanqin Zhang, Ju Zhu, Yunbo Xie","doi":"10.2147/PPA.S644041","DOIUrl":"10.2147/PPA.S644041","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to explore the multidimensional needs of patients and their caregivers during home-based nutritional management after esophageal cancer surgery, and to provide evidence for developing targeted nursing interventions using patient journey mapping.</p><p><strong>Methods: </strong>We used a descriptive qualitative design. From December 2025 to January 2026, we conducted semi-structured interviews with 11 patients who had undergone esophageal cancer surgery and 9 caregivers at a tertiary general hospital in Chongqing, China. We analyzed the data using traditional content analysis and constructed a patient journey map.</p><p><strong>Results: </strong>The patient journey map, structured across four stages and three analytical dimensions, identified 31 sub-themes across these stages. From participants' retrospective accounts, three core barriers were identified in this study: cognitive-behavioral barriers, cultural-cognitive dissonance, and fragmented post-discharge support systems. Moreover, these difficulties were interrelated and associated with eroded confidence in nutritional management, persistent worry about recurrence, and a sense of helplessness. This predicament persisted throughout the rehabilitation period, suggesting a structural gap within the current healthcare system: a mismatch between patients' ongoing need for nutritional guidance and the limited professional support available.</p><p><strong>Conclusion: </strong>Given the prolonged and complex nature of home-based nutritional management after esophagectomy, and to address patients' need for sustained professional guidance, this study outlines a theoretical intervention framework that integrates three strategies-phase-specific education, culturally tailored dietary support, and a continuous care loop linking hospital and home-drawing on the advantages of digital health technologies. The feasibility and implementation pathways of this framework warrant further exploration.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"644041"},"PeriodicalIF":2.6,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Behavioral Pathways Associated with Nutritional Self-Management Among Patients Undergoing Maintenance Hemodialysis: A Cross-Sectional IMB Model-Guided Path Analysis.","authors":"Ting Wu, Liping Wang, Hui Si, Weiwei Zhang, Weixiang Luo, Jiaxiu Deng","doi":"10.2147/PPA.S647632","DOIUrl":"10.2147/PPA.S647632","url":null,"abstract":"<p><strong>Purpose: </strong>To examine factors associated with nutritional self-management behavior and their hypothesized relationships within the Information-Motivation-Behavioral Skills (IMB) framework among patients undergoing maintenance hemodialysis (MHD).</p><p><strong>Patients and methods: </strong>This single-center cross-sectional study included a convenience sample of 215 patients undergoing MHD at a tertiary hospital in Shenzhen, China, between January and May 2026. Questionnaires assessed hemodialysis knowledge, health beliefs, social support, self-management, and nutritional self-management behavior. Pearson correlations and multiple linear regression were analyzed. Because the initially planned latent-variable structural equation model showed inadequate measurement-model fit, an observed-variable path analysis using composite scores was conducted. Indirect associations were estimated using 5000 bias-corrected bootstrap resamples.</p><p><strong>Results: </strong>The mean nutritional self-management behavior score was 86.47 ± 9.86 (scoring rate, 72.06%). In the regression model, health beliefs (β = 0.190, P = 0.003) and self-management (β = 0.365, P < 0.001) were positively associated with nutritional self-management behavior. In the path model, health beliefs had the largest coefficient for self-management (β = 0.437, P = 0.001), and self-management had the largest coefficient for nutritional self-management behavior (β = 0.380, P < 0.001). Hemodialysis knowledge, health beliefs, and social support showed significant indirect associations through self-management; the largest was for health beliefs (β = 0.166). Explained variance was 25.7% for self-management and 33.2% for nutritional self-management behavior.</p><p><strong>Conclusion: </strong>These cross-sectional associations provide preliminary evidence consistent with the hypothesized IMB framework. Longitudinal and intervention studies are needed to establish temporal relationships and evaluate potential intervention strategies.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"647632"},"PeriodicalIF":2.6,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does Provider's Supportive Communication Enhance Trust and Treatment Adherence Attitudes in Mild and Severe Dysfunction Scenarios? A Web-Based Experimental Study.","authors":"Rosanna Matthäus, Hojjat Daniali, Magne Arve Flaten","doi":"10.2147/PPA.S614208","DOIUrl":"https://doi.org/10.2147/PPA.S614208","url":null,"abstract":"<p><strong>Purpose: </strong>The way healthcare providers communicate with patients can influence patients' trust in providers and their attitudes toward treatment adherence. The present study investigated whether such influences of providers' communication can be modulated by dysfunction severity and participant gender.</p><p><strong>Participants and methods: </strong>In an online experiment, participants (N = 508) were instructed to imagine having either mild or severe olfactory dysfunction (OD). They were then randomized to watch a video of a healthcare provider delivering an olfactory training (OT) as a treatment for OD, with either neutral or emotionally supportive communication. Participants then rated their perceived trust in the provider, attitudes toward treatment effectiveness, treatment engagement, treatment unpleasantness, and treatment risk. State anxiety was measured before and after watching the videos.</p><p><strong>Results: </strong>Supportive communication elicited higher trust in the provider than neutral communication, with a small to medium effect size (Cohen's <i>d</i> = 0.36). While supportive communication did not directly affect anxiety, exploratory analyses showed that higher levels of trust in the supportive communication group were linked to lower anxiety. Moreover, supportive communication elicited higher treatment effectiveness attitude. No other treatment adherence attitudes were affected by the communication. Dysfunction severity did not affect trust in provider and treatment adherence attitudes. Men reported lower perceived treatment unpleasantness than did women, and no other gender differences emerged.</p><p><strong>Conclusion: </strong>Supportive communication may elicit higher trust in provider independent of dysfunction severity and gender, however, likely with a smaller effect than previously assumed, and with no influence on attitudes toward adherence to treatment. Gender differences in perceived attitudes toward treatment adherence appear to be limited.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"614208"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13637507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149112210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Qualitative Study on Self-Perceived Burden in Elderly Patients with Diabetes and Frailty Based on Social Ecological Theory.","authors":"Mingzhu Chen, Xiaofen Shi, Jing Tan, Mengyu Wang, Xia Pan, Xiao-Lei Chen","doi":"10.2147/PPA.S624736","DOIUrl":"https://doi.org/10.2147/PPA.S624736","url":null,"abstract":"<p><strong>Objective: </strong>To explore the formation mechanism of self-perceived burden (SPB) in elderly patient with diabetes with frailty from the perspective of social ecological theory.</p><p><strong>Methods: </strong>Using purposive sampling, 21 frail elderly patient with diabetes (aged ≥60 years, Tilburg Frailty Index ≥5, Self-Perceived Burden Scale score ≥20) were recruited from a tertiary hospital in Wuxi, China. One-on-one semi-structured interviews were conducted using an interview guide based on social ecological theory. Data were analyzed with NVivo 12.0 using theory-driven and data-driven qualitative content analysis.</p><p><strong>Results: </strong>Five themes with core connotations and 12 sub themes were identified: (1) Physiological disability: the loss of self-integrity caused by the progression of complications, debilitating experiences and impairment of self-care; (2) Management dilemma: management frustration and loss of life meaning caused by the conflict between subjective efforts and poor outcomes; (3) Relationship tension: the common sense of emotional debt in spousal care, intergenerational support and social withdrawal; (4) Environmental exclusion: the double marginalization experience caused by barriers to the physical environment at home and the intensification of the digital divide; (5) System imbalance: the sense of powerlessness caused by the lack of humanistic care in medical services and limited medical insurance support.</p><p><strong>Conclusion: </strong>SPB is shaped by multi‑level interactions within the social ecological system. Findings can inform clinical practice and policy: stratified psychological interventions, family support optimization, age‑friendly environmental and digital inclusion, and chronic disease insurance refinement. Nurses can serve as cross‑level integrators in implementing these strategies.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"624736"},"PeriodicalIF":2.6,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13632690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiajia Wu, Lei He, Jing Wang, Xiangyu Wang, Bingqing Lu, Zhi Zhao, Sijia Sun, Bo Chen, Cuilian Chen
{"title":"Barriers and Facilitators to the Initiation of Home-Based Exercise Rehabilitation After Radiofrequency Catheter Ablation for Atrial Fibrillation: A TDF-Based Qualitative Study.","authors":"Jiajia Wu, Lei He, Jing Wang, Xiangyu Wang, Bingqing Lu, Zhi Zhao, Sijia Sun, Bo Chen, Cuilian Chen","doi":"10.2147/PPA.S624476","DOIUrl":"https://doi.org/10.2147/PPA.S624476","url":null,"abstract":"<p><strong>Purpose: </strong>Home-based exercise rehabilitation is important for recovery after atrial fibrillation (AF) ablation. However, the barriers and facilitators influencing the initiation of home-based exercise rehabilitation during the early post-ablation recovery phase remain insufficiently understood. This study aimed to explore the barriers and facilitators influencing the initiation of home-based exercise rehabilitation among patients following radiofrequency catheter ablation for AF, guided by the Theoretical Domains Framework (TDF).</p><p><strong>Patients and methods: </strong>A descriptive qualitative study was conducted using purposive sampling. Twenty patients who had undergone radiofrequency catheter ablation for AF were recruited from a tertiary general hospital in Jiangsu Province, China. Formal data collection was conducted from August to December 2025.Face-to-face semi-structured interviews were conducted individually during routine follow-up approximately one month after ablation. The phenomenon under investigation was the initiation of home-based exercise rehabilitation during the early recovery phase, referring to patients' transition toward intentional, planned exercise activities performed at home after discharge and recommended or guided by healthcare professionals. Data were analysed using qualitative content analysis with a hybrid inductive-deductive approach informed by the TDF.</p><p><strong>Results: </strong>Factors influencing the initiation of home-based exercise rehabilitation were categorized into promoting and impeding factors. A total of 11 influencing factors were identified: 3 promoting factors (benefit-driven motivation, trust and recognition of professionals, and family responsibility as a motivator) and 8 impeding factors (lack of exercise knowledge, inadequate skill mastery, low exercise self-efficacy, distress from physical symptoms, poor resource accessibility, negative emotional distress, and absence of exercise plans).</p><p><strong>Conclusion: </strong>The initiation of home-based exercise rehabilitation after radiofrequency catheter ablation for AF is influenced by multiple interacting individual, professional, and contextual factors. Support strategies should address patients' knowledge and skills, confidence, symptom-related concerns, access to professional guidance and rehabilitation resources, and competing social responsibilities to facilitate the initiation of home-based exercise rehabilitation during early recovery.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"624476"},"PeriodicalIF":2.6,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lixia Wang, Xiyan He, Yan Lei, Jiao Liu, Sai Li, Zhiyun Ning, Xuemei Zhang
{"title":"Blood Glucose Management Behaviour Among Haemodialysis Patients with Diabetes: A Qualitative Study Guided by the Theory of Planned Behaviour.","authors":"Lixia Wang, Xiyan He, Yan Lei, Jiao Liu, Sai Li, Zhiyun Ning, Xuemei Zhang","doi":"10.2147/PPA.S618203","DOIUrl":"https://doi.org/10.2147/PPA.S618203","url":null,"abstract":"<p><strong>Objective: </strong>To utilise the Theory of Planned Behaviour as a theoretical framework, employing qualitative interviews to gain an in-depth understanding and analysis of the motivations and influencing factors of blood glucose management behaviours among haemodialysis patients with diabetes.</p><p><strong>Methods: </strong>Employing the phenomenological research method within qualitative research, in-depth semi-structured interviews were conducted with 12 haemodialysis patients with diabetes. Themes were then categorised using Colaizzi's seven-step content analysis method.</p><p><strong>Results: </strong>Themes were categorised according to the Theory of Planned Behaviour, yielding four categories: 1. Attitudes towards blood glucose management: perceived benefits and perceived burdens; 2. Subjective norms for blood glucose management: injunctive norms and descriptive norms; 3. Perceived behavioural control for blood glucose management: facilitating factors and impeding factors; 4. Behavioural intention versus actual behaviour: high intention-high execution, high intention-low execution, low intention-low execution, comprising nine themes in total.</p><p><strong>Conclusion: </strong>Using the Theory of Planned Behaviour, this study identifies key modifiable factors underlying glycaemic self-management among diabetic patients on maintenance haemodialysis, including conflicting attitudes, social-norm influences, and major perceived-behavioural-control barriers that produce intention-behaviour gaps. Interventions should shift from knowledge-only education towards enhancing patients' practical execution and perceived control. Individualised feasible management plans, together with integrated support from healthcare teams, families and social resources, are needed to address real-world barriers and improve glycaemic self-management outcomes for this patient group.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"618203"},"PeriodicalIF":2.6,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tina Tavakol, Rezvan Chaharlang, Maryam Zahedi, Mariyeh Najafi, Omid Nikpayam
{"title":"Adherence to Diabetes Self-Care Practices Across Demographic and Clinical Characteristics Among Patients with Type 2 Diabetes.","authors":"Tina Tavakol, Rezvan Chaharlang, Maryam Zahedi, Mariyeh Najafi, Omid Nikpayam","doi":"10.2147/PPA.S633712","DOIUrl":"https://doi.org/10.2147/PPA.S633712","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to examine the level of adherence to self-care behaviors across socio-demographic and clinical characteristics in patients with type 2 diabetes mellitus (T2DM).</p><p><strong>Methods: </strong>A total of 270 patients with diabetes who were referred to two medical centers in Gorgan, Iran, participated in this cross-sectional study. We assessed adherence using a reliable questionnaire, the Summary of Diabetes Self-Care Activities (SDSCA). The anthropometric measurements and blood pressure were assessed based on a standard protocol. The biochemical variables were gathered based on the medical documents of the centers. To compare adherence scores across clinical and demographic variables, independent <i>t</i>-test and ANOVA were used. A p-value less than 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The mean age of participants was 57.16 ± 9.20 years, and nearly 66% of patients were female. The mean SDSCA score was 3.50 ± 0.87. Regarding self-care domains, the highest adherence scores were observed for medication use (6.07 ± 1.42) and foot care (6.05 ± 1.50), while blood glucose monitoring (2.16 ± 1.89) yielded the lowest score. A significant difference was observed between adherence scores and better glycemic control (P<0.001) and a more favorable lipid profile (P=0.001). No significant difference was observed between factors such as age, gender, duration of diabetes, BMI, and type of medication used with total score adherence.</p><p><strong>Conclusion: </strong>Overall adherence to self-care practices among T2DM patients was suboptimal. Moreover, higher adherence to self-care behaviors is associated with a better metabolic situation. Targeted educational and awareness programs are recommended to enhance self-care behaviors and optimize metabolic outcomes in this population.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"633712"},"PeriodicalIF":2.6,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, Attitudes, and Practices of Patients with Urolithiasis Regarding Stone Examination Methods: A Cross-Sectional Study in China.","authors":"Xiaodong Liu, Zhaoyuan Gong, Sichen Liu, Xuejie Li, Yanhu Wang, Lianpeng Yang, Yu Zhao, Xing Zheng","doi":"10.2147/PPA.S631885","DOIUrl":"https://doi.org/10.2147/PPA.S631885","url":null,"abstract":"<p><strong>Background: </strong>This study aims to assess the knowledge, attitudes, and practices (KAP) of patients with urolithiasis regarding stone examination methods.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted in Wuhai City, Inner Mongolia Autonomous Region, between September 16, 2023, and December 30, 2024. Data were collected using a structured questionnaire, which included demographic information and KAP-related items. KAP scores were calculated, and their variations across different demographic groups were analyzed, with structural equation modeling (SEM) used to examine the interrelationships among the KAP dimensions.</p><p><strong>Results: </strong>A total of 457 valid responses were obtained, with 251 participants (54.92%) being male. Among the respondents, 373 (81.62%) reported experiencing pain in the lower back or abdomen. The mean knowledge, attitude, and practice scores were 11.23±2.98 (possible range: 0-18), 19.18±1.67 (possible range: 4-20), and 18.04±2.88 (possible range: 4-20), respectively. The mediation analysis showed that knowledge directly affected attitude (β = 0.462, P = 0.015) and practice (β = 0.312, P = 0.013), and attitude directly affected practice (β = 0.501, P = 0.009), as well as the knowledge indirectly affected practice (β = 0.231, P = 0.012).</p><p><strong>Conclusion: </strong>Patients with urolithiasis demonstrated inadequate knowledge but self-reported highly positive attitudes and proactive practices, which were likely influenced by social desirability bias. Targeted educational interventions are urgently needed to translate these positive declarations into genuine clinical examination adherence.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"631885"},"PeriodicalIF":2.6,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jingwen Song, Norafisyah Makhdzir, Zarina Haron, Chunping Qin, Li Wang
{"title":"Information Quality Requirements for AI-Generated Patient Education Materials in Diabetic Foot Ulcer Care: A Directed Qualitative Content Analysis of Patient and Nurse Perspectives.","authors":"Jingwen Song, Norafisyah Makhdzir, Zarina Haron, Chunping Qin, Li Wang","doi":"10.2147/PPA.S626817","DOIUrl":"https://doi.org/10.2147/PPA.S626817","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the information quality requirements of artificial intelligence generated patient education materials for diabetic foot ulcers from the perspectives of patients and nurses.</p><p><strong>Patients and methods: </strong>This single-center qualitative study was conducted at the Fifth Affiliated Hospital of Guangxi Medical University, China, from November 2025 to June 2026. Maximum-variation purposive sampling recruited 15 hospitalized patients with diabetic foot ulcers and 10 nurses. Saturation was assessed separately for each group and defined as no new codes, categories, or relevant insights. It was reached after 13 patient and 8 nurse interviews, with two additional interviews per group for confirmation. Face-to-face semi-structured interviews used standardized artificial intelligence generated diabetic foot ulcer education material as a discussion stimulus. Data were analyzed using directed content analysis guided by Wang and Strong's information quality framework.</p><p><strong>Results: </strong>Five themes and 17 subthemes were identified. Four themes mapped to Wang and Strong's framework: intrinsic information quality (accuracy, believability, objectivity, and reputation); contextual information quality (relevancy, completeness, timeliness, appropriate amount of data, and value-added); representational information quality (ease of understanding, interpretability, consistent representation, and concise representation); and accessibility information quality (accessibility and access security). An additional specific theme comprised clinical safety and actionability. Both groups valued reliable, relevant, understandable, and accessible information, but their priorities differed: nurses emphasized clinical accuracy, professional review, and the risks of unsafe recommendations, whereas patients prioritized relevance to current wound-care needs, ease of understanding and access, and clear guidance for self-care.</p><p><strong>Conclusion: </strong>Patients and nurses showed different but complementary priorities. Clinical safety and actionability extend conventional information quality considerations. Artificial intelligence may support educational content generation. However, a professional review is necessary for clinically sensitive information, and patient input is essential to ensure usability. Future studies should refine and validate these requirements across settings and user groups.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"20 ","pages":"626817"},"PeriodicalIF":2.6,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149112131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}