Oral diseases最新文献_第8页

Neutrophil Extracellular Traps in Oral Diseases. 口腔疾病中的中性粒细胞胞外捕获器

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-12 DOI: 10.1111/odi.15197

Pengfei Gao, Jun Zhou, Lu Sun, Dayong Liu

{"title":"Neutrophil Extracellular Traps in Oral Diseases.","authors":"Pengfei Gao, Jun Zhou, Lu Sun, Dayong Liu","doi":"10.1111/odi.15197","DOIUrl":"https://doi.org/10.1111/odi.15197","url":null,"abstract":"Objective: To summarize the current knowledge of the neutrophil extracellular traps (NETs) and its critical role in various oral diseases.Methods: We reviewed the recent research on NETs through PubMed and Web of Science. An analysis of recent research results was summarized from three aspects: NETs induction and formation, functions of NETs, and NETs in oral diseases.Results: The relationship between neutrophils and NETs is critical to the body's defense against microbial invasion. NETs can effectively combat pathogens with an anti-inflammatory effect and meanwhile it can contribute to inflammation. Moreover, it can synergize with other immune cells to respond to stimuli, such as pathogens, host-derived mediators, and drugs. It was revealed that NETs play different roles to influence various oral diseases like periodontitis, endodontic infection, oral mucosal diseases, maxillofacial tumors, and many other oral diseases.Conclusion: The balance between the protective and potentially harmful effects of NETs is a key factor in determining the outcome of infections and inflammatory responses. The role of NETs in oral diseases needs to be further studied to enable better understanding of its role in the different oral diseases.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Aphthous Stomatitis and Sleep Quality Factors: A Comprehensive Analysis. 复发性口腔炎与睡眠质量因素：综合分析

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-07 DOI: 10.1111/odi.15189

Sina Bazmi, Zahra Mohammadi, Reza Tabrizi, Maryam Kazemi

{"title":"Recurrent Aphthous Stomatitis and Sleep Quality Factors: A Comprehensive Analysis.","authors":"Sina Bazmi, Zahra Mohammadi, Reza Tabrizi, Maryam Kazemi","doi":"10.1111/odi.15189","DOIUrl":"https://doi.org/10.1111/odi.15189","url":null,"abstract":"Background: Due to the unclear etiology of recurrent aphthous stomatitis (RAS), a painful and distressing condition with a high prevalence, the researchers have hypothesized a connection between sleep quality and RAS.Methods: The cross-sectional study enrolled 10,138 Fasa Cohort Study participants aged 35-70 years. Various sleep quality factors were calculated and categorized based on the Pittsburgh Sleep Questionnaire.Results: Among 9030 subjects finally included with RAS prevalence of 20.2%, adjusted logistic regression showed significant odds ratios (ORs) in subjects who sleep < 5 h (OR = 1.44, 95%CI 1.25, 1.66), have sleep latencies of more than 60 min (OR = 1.37, 95%CI 1.11, 1.69), have sleep efficiencies of 65%-75% (OR = 1.55, 95%CI 1.21, 1.98), or regularly go to bed after 11 p.m. (OR = 1.23, 95%CI 1.11, 1.37). Subgroup analyses indicated no significant associations between RAS and various sleep factors in individuals who worked night shifts, and stronger associations were observed in men than women.Conclusion: The study found a significant positive association between RAS and sleep quality factors such as shorter duration, lower efficiency, longer latency, later bedtime, and regular sleeping pill use. Establishing early and sufficient sleep and addressing sleep onset disturbances by adhering to sleep hygiene principles should be prioritized in individuals with RAS.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Binary Grading Better Than WHO System for Grading Epithelial Dysplasia? A Systematic Review and Meta-Analysis. 二元分级比 WHO 上皮增生异常分级系统更好吗？系统回顾与元分析》。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-06 DOI: 10.1111/odi.15160

Divya Gopinath, Cheng Yung On, Sajesh Kalkandi Veettil, W M Tilakaratne

{"title":"Is Binary Grading Better Than WHO System for Grading Epithelial Dysplasia? A Systematic Review and Meta-Analysis.","authors":"Divya Gopinath, Cheng Yung On, Sajesh Kalkandi Veettil, W M Tilakaratne","doi":"10.1111/odi.15160","DOIUrl":"10.1111/odi.15160","url":null,"abstract":"Background: This meta-analysis summarizes the current evidence on the intra- and inter-observer agreement between WHO and the binary grading systems used to assess epithelial dysplasia (ED).Methods: A systematic search for observational studies that compared the level of agreement among pathologists between WHO and binary grading systems for ED was conducted using three databases: Medline, Scopus, and EBSCOhost. For the meta-analysis, summary estimations of kappa value (κ) and standard error (SE) were utilized.Results: The pooled analysis of observations by 46 pathologists from a total of eight studies showed better interobserver agreement in the interpretation of ED for the binary system (κ = 0.31; 95% confidence interval [CI], 0.23-0.40) in comparison with the WHO (κ = 0.14; 95% CI, 0.10-0.19). The intra-observer agreement was reported only by five studies and was also found to be higher for the binary system (κ = 0.44; 95% CI, 0.31-0.57) compared to the WHO (κ = 0.25; 95% CI, 0.11-0.39).Conclusions: Our results validate that the binary system has better overall intra-observer and interobserver agreement than the WHO system. Further studies with larger cohorts are mandatory before clinically relevant conclusions are drawn, as evidence remains inadequate.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter About the Article "Hydroxychloroquine Is Effective in Oral Lichen Planus". 关于 "羟氯喹对口腔扁平苔藓有效 "一文的来信

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-06 DOI: 10.1111/odi.15177

Wei-Zhen Tang, Xue-Bing Chen, Tai-Hang Liu

引用次数: 0

Hormone Replacement Therapy Relieves Periodontitis by Inhibiting Alveolar Bone Loss and Inflammation. 激素替代疗法通过抑制牙槽骨流失和炎症缓解牙周炎

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-06 DOI: 10.1111/odi.15192

Ying Man, Jianyong Qin, Hongliang Qiu, Yiying Wang, Xinyue Zhang, Shengjie Yan

{"title":"Hormone Replacement Therapy Relieves Periodontitis by Inhibiting Alveolar Bone Loss and Inflammation.","authors":"Ying Man, Jianyong Qin, Hongliang Qiu, Yiying Wang, Xinyue Zhang, Shengjie Yan","doi":"10.1111/odi.15192","DOIUrl":"10.1111/odi.15192","url":null,"abstract":"Objective: Hormone replacement therapy (HRT) is a commonly used strategy for treating menopausal symptoms, while its relation with periodontitis remains unclear. This study aimed to explore the potential effects of HRT on periodontitis, mainly in aspects of bone loss and inflammation.Methods: The alveolar bone height (ABH), alveolar bone thickness (ABT), and bone mineral density (BMD) were measured in menopausal women with periodontitis who had received HRT or had not received HRT by cone beam computed tomography. Based on a rat model of periodontitis, the alveolar bone loss was evaluated by micro-computed tomography and bone-related biochemical markers. The expression/levels of inflammatory markers were measured to reflect periodontal inflammation.Results: Although the differences were not all significant in each premolars/molars, the mesial/distal ABH and buccal/lingual ABT were lower, and the mesial/distal BMD was higher in patients in the HRT group than those in the control group. In a rat model of periodontitis, the alveolar bone loss was relieved by HRT. Additionally, HRT significantly weakened the elevation of inflammatory markers, including TNF-α, IL-1β, and IL-6 in periodontitis rats.Conclusions: HRT contributes to the remission of periodontitis by inhibiting alveolar bone loss and inflammation.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Second Events After Curative-Intent Treatment for Lip Cancer: Navigating the Path of Follow-Up Care. 唇癌治愈性治疗后的第二次事件：引领后续护理之路。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-06 DOI: 10.1111/odi.15194

Fábio Muradás Girardi, Amanda de Farias Gabriel, Vivian Petersen Wagner, Manoela Domingues Martins

{"title":"Second Events After Curative-Intent Treatment for Lip Cancer: Navigating the Path of Follow-Up Care.","authors":"Fábio Muradás Girardi, Amanda de Farias Gabriel, Vivian Petersen Wagner, Manoela Domingues Martins","doi":"10.1111/odi.15194","DOIUrl":"10.1111/odi.15194","url":null,"abstract":"Objective: We aimed to investigate the pattern, risk, and treatment of subsequent events after curative-intent treatment of lip cancer.Methods: This retrospective cohort study included 313 patients treated for lip cancer from 2011 to 2021 in a tertiary oncological center.Results: After a median follow-up time of 29.16 months, 145 (46.32%) patients presented with second primary tumors, 93% of which were skin carcinomas. Locoregional recurrence occurred in 7.9% of cases, with 2.5% with nodal recurrence. The 1-, 5-, and 10-year cumulative second primary tumor probabilities were 32.8%, 60.92%, and 70.92%, respectively. A higher risk was observed in elderly patients and basal cell carcinoma cases located on the cutaneous surface of the upper lip. Regional metastasis but not second primary tumors negatively impacted survival.Conclusions: Our study helps fill a literature gap, structuring specific recommendations regarding evaluations and follow-up protocols for patients with lip cancer. Since cutaneous second primary tumors were the most common second event, standard skin examination is key. Age and histology were significant predictors for second primary tumors. For cases of locally advanced lip squamous cell carcinoma, standard guidelines for head and neck cancer must be followed.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histone Lysine Lactylation (Kla)-induced BCAM Promotes OSCC Progression and Cis-Platinum Resistance. 组蛋白赖氨酸乳化（Kla）诱导的 BCAM 促进 OSCC 进展和顺铂抗性

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-06 DOI: 10.1111/odi.15179

Guangzhao Huang, Su Chen, Jialu He, Honglin Li, Zhongkai Ma, Grace Paka Lubamba, Lei Wang, Zhiyong Guo, Chunjie Li

{"title":"Histone Lysine Lactylation (Kla)-induced BCAM Promotes OSCC Progression and Cis-Platinum Resistance.","authors":"Guangzhao Huang, Su Chen, Jialu He, Honglin Li, Zhongkai Ma, Grace Paka Lubamba, Lei Wang, Zhiyong Guo, Chunjie Li","doi":"10.1111/odi.15179","DOIUrl":"https://doi.org/10.1111/odi.15179","url":null,"abstract":"Objective: Histone lysine lactylation (Kla) plays a vital role in cancer progression. However, the prognostic value of histone Kla in oral squamous cell carcinoma (OSCC) remains unclear.Materials and methods: OSCC RNA expression data were obtained from the TCGA and GEO databases. We explored the prognostic value of histone Kla in OSCC via constructing a Cox model and determined the role of Kla in OSCC drug susceptibility and tumor microenvironment (TME). In addition, the biological roles of candidate biomarkers were identified.Results: A total of 1223 Kla-specific genes were obtained, with 228 DEKlaGs in OSCC. GO and KEGG enrichment analyses suggested that DEKlaGs contributed to inflammatory and cancer progression. A Cox model in accordance with BCAM, CGNL1, DGKG, and OLR1 could predict OSCC patient prognosis accurately. Subsequently, Kla-induced prognostic genes were identified to play a crucial role in OSCC drug therapy and TME. Moreover, BCAM was identified as a biomarker that promoted OSCC invasion, angiogenesis, and chemotherapy resistance.Conclusion: Kla was identified to be associated with OSCC prognosis, drug therapy, and TME. Histone Kla-induced BCAM was identified to play a crucial role during OSCC progression, suggesting that Kla is promising to be a novel therapeutic target for OSCC.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is There a Role for Colchicine in the Treatment of Oral Mucous Membrane Pemphigoid? 秋水仙碱在治疗口腔粘膜丘疹性脓疱病中有作用吗？

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-04 DOI: 10.1111/odi.15193

E Fribourg, V Chuy, M Fenelon, S Catros, J C Fricain

引用次数: 0

Accurate Risk Prediction Model for Surgical Site Infection After Lower Third Molar Surgery. 下第三磨牙手术后手术部位感染的精确风险预测模型

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-03 DOI: 10.1111/odi.15185

HaiPeng Yu

引用次数: 0

Evaluating Dentists' Understanding of Dry Mouth Management: An International Cross-Sectional Study. 评估牙医对口腔干燥管理的理解：一项国际横断面研究。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-11-03 DOI: 10.1111/odi.15176

Anas B Alsalhani, Mohammad Zakaria Nassani, Mohammed Noushad, Bassel Tarakji, Samer Rastam, Azza Sioufi, Basem Sabbagh, Salah A Yousief, Abdulaziz Binrayes, Mudassir Hussain, Mohammed Arshad, Tahsinul Haque, Fatema Akhter, Shamil Fayis, Rami Taher Mousa, Mowaffak Adi, Omar Kujan

{"title":"Evaluating Dentists' Understanding of Dry Mouth Management: An International Cross-Sectional Study.","authors":"Anas B Alsalhani, Mohammad Zakaria Nassani, Mohammed Noushad, Bassel Tarakji, Samer Rastam, Azza Sioufi, Basem Sabbagh, Salah A Yousief, Abdulaziz Binrayes, Mudassir Hussain, Mohammed Arshad, Tahsinul Haque, Fatema Akhter, Shamil Fayis, Rami Taher Mousa, Mowaffak Adi, Omar Kujan","doi":"10.1111/odi.15176","DOIUrl":"https://doi.org/10.1111/odi.15176","url":null,"abstract":"Objective: Studying dentists' knowledge of dry mouth management is crucial for effective diagnosis and treatment, improving patient outcomes and oral health. This study aimed to evaluate their knowledge and awareness of dry mouth and its predictors.Materials and methods: A pre-validated online survey was administered to a convenience sample of dentists across six countries. The questionnaire evaluated knowledge in various domains, including predisposing factors, diagnosis, clinical signs and symptoms, and management of dry mouth.Results: A total of 884 dentists participated. Knowledge and awareness of dry mouth management varied significantly between countries (p < 0.05). Overall, 34.3% of participants demonstrated good knowledge, while 53.7% had moderate knowledge. Regarding management awareness, 55.4% had good awareness and 35.5% had moderate awareness. A majority (69.2%) showed good knowledge of common signs, symptoms, and consequences of dry mouth. Significant predictors of better knowledge and awareness included the country of practice and attendance at continuing education courses on dry mouth.Conclusion: The findings suggest that dentists in the surveyed countries require improved education on dry mouth and its management. Dental educators and healthcare planners can use this data to design targeted continuing education activities to enhance knowledge and awareness of dry mouth.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0