Oral diseases最新文献

Corrigendum to "A Three-Long Non-Coding RNA Signature That Predicts Tongue Squamous Cell Carcinoma Prognosis". “预测舌鳞状细胞癌预后的三长非编码RNA标记”的更正。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-05-05 DOI: 10.1111/odi.70361

引用次数: 0

Predicting Pain After Tooth Extraction With Easy-to-Collect Preoperative Variables. 用易于收集的术前变量预测拔牙后疼痛。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-05-05 DOI: 10.1111/odi.70360

Vincent Saliba, Christian Dualé, Radhouane Dallel, Antoine Berberi, Aurélien Mulliez, Laurent Devoize

{"title":"Predicting Pain After Tooth Extraction With Easy-to-Collect Preoperative Variables.","authors":"Vincent Saliba, Christian Dualé, Radhouane Dallel, Antoine Berberi, Aurélien Mulliez, Laurent Devoize","doi":"10.1111/odi.70360","DOIUrl":"https://doi.org/10.1111/odi.70360","url":null,"abstract":"Objectives: To examine the determinants of acute pain following tooth extraction, within a set of factors belonging to different domains: biometry, dental nosology and anatomy, psychology toward pain and surgery, and surgical procedure.Methods: Participants were recruited in two centres in France and Lebanon. A 'simple extraction' (161 patients) and a 'wisdom teeth/tooth' group (at least mandibular) (115 patients) were studied separately. Postoperative pain and total analgesic drug intake (over 5 days) were both expressed as a composite score. Both scores were ranked within each surgery group, and their sum was the primary outcome, which was analysed by multivariable linear mixed models after a factor selection.Results: In the simple extraction group, the primary outcome was predicted positively by preoperative fearfulness (defined by a composite of various phobias) and preoperative dental pain, and negatively by age (≥ 60) and a previous tooth extraction. In the wisdom teeth/tooth group, it was predicted positively by preoperative fearfulness and pain catastrophising, and negatively by a local inflammatory context and preoperative dental pain.Conclusions: Whereas postoperative pain was constantly favoured by psychological distress, age and other dental factors had different influences on postoperative pain depending on the type of extraction.Trial registration: ClinicalTrials.gov identifier: NCT05405088.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mastication Regulates Nitrate Homeostasis Through Lipid Raft-Mediated Sialin Translocation. 咀嚼通过脂质筏介导的Sialin易位调节硝酸盐稳态。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-05-05 DOI: 10.1111/odi.70359

Mingwei Yue, Xue Wang, Meizhi Ning, Huan Liu, Jinsong Wang, Xiaogang Wang, Songlin Wang, Lei Hu

{"title":"Mastication Regulates Nitrate Homeostasis Through Lipid Raft-Mediated Sialin Translocation.","authors":"Mingwei Yue, Xue Wang, Meizhi Ning, Huan Liu, Jinsong Wang, Xiaogang Wang, Songlin Wang, Lei Hu","doi":"10.1111/odi.70359","DOIUrl":"https://doi.org/10.1111/odi.70359","url":null,"abstract":"Objective: To investigate the role of mastication on the salivary nitrate transport and elucidate the underlying mechanisms.Methods: Systemic nitrate levels were clinically compared between individuals with masticatory dysfunction and healthy individuals. Behavioral assessments were performed in mice with reduced masticatory activity to examine the impact on anxiety-like behavior. Mechanical stimulation was applied to salivary gland epithelial cells and tissues to explore the expression, localization, and translocation mechanisms of Sialin, a nitrate transporter encoded by the Slc17a5.Results: Individuals with impaired mastication exhibited significantly lower systemic nitrate levels compared to healthy controls. In mice, decreased masticatory activity was associated with increased anxiety-like behavior. In vitro, mechanical force stimulated the upregulation and apical translocation of Sialin in human salivary gland epithelial cells (HSGs). Sialin was predominantly localized within lipid rafts, and its force-induced translocation was mediated by activation of the Piezo1 channel, which facilitated the movement of lipid rafts to the apical membrane, thereby enhancing nitrate secretion.Conclusion: Mastication sustains nitrate homeostasis and mitigates anxiety-like behavior in mice by mechanically activating the Piezo1 channel, thus facilitating the lipid raft-mediated translocation of Sialin to the apical membrane in salivary gland cells.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Odontogenic Keratocysts Don't Harbor BRAF Mutation: A Genetic and Immunohistochemical Analysis. 牙源性角化囊肿不携带BRAF突变：遗传和免疫组织化学分析。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-05-05 DOI: 10.1111/odi.70358

Raisa Severino-Lazo, Jéssica da Silva Cunha, Allan Vinícius Martins-de-Barros, Karina Helen Martins, Adauto Gomes Barbosa Neto, Jorge Esquiche León, Marianne de Vasconcelos Carvalho

引用次数: 0

A Rare LAMP3 Gene Variant Drives Enhanced Epithelial Cell Apoptosis and Salivary Gland Dysfunction. 一种罕见的LAMP3基因变异驱动上皮细胞凋亡和唾液腺功能障碍增强。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-05-05 DOI: 10.1111/odi.70347

Hitomi Ono-Minagi, Peter D Burbelo, Natalie Atyeo, Sandra A Afione, Changyu Zheng, John A Chiorini

引用次数: 0

Narrow Band Imaging by Novice Raters After Short Training: A Pilot Feasibility Study of Diagnostic Accuracy and Repeatability. 短期训练后的新手评分员窄带成像：诊断准确性和可重复性的试点可行性研究。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-04-26 DOI: 10.1111/odi.70357

Matteo Zotti, Katia Rupel, Edgar Andrea Keller, Griselda Pedroso Acosta, Roberto Di Lenarda, Matteo Biasotto, Giulia Ottaviani

{"title":"Narrow Band Imaging by Novice Raters After Short Training: A Pilot Feasibility Study of Diagnostic Accuracy and Repeatability.","authors":"Matteo Zotti, Katia Rupel, Edgar Andrea Keller, Griselda Pedroso Acosta, Roberto Di Lenarda, Matteo Biasotto, Giulia Ottaviani","doi":"10.1111/odi.70357","DOIUrl":"https://doi.org/10.1111/odi.70357","url":null,"abstract":"Objective: To pilot the feasibility, diagnostic accuracy, and repeatability of the Takano NBI-based IPCL classification when applied by novice raters after short formal training.Methods: Ten dental students classified 90 oral lesions shown as paired white-light and NBI images in two sessions, 4 weeks apart. Scores were recorded on an ordinal scale (0-4), where category 0 denoted hyperplasia or clinically normal mucosa, while categories 1-4 represented increasing degrees of epithelial dysplasia or invasive disease. Histopathology served as the reference standard.Results: The 90 lesions comprised 38 hyperplastic/normal, 29 dysplastic, and 23 invasive carcinomas. Mean agreement with histology was 18.8% at T1 and 21.0% at T2, with weighted kappa values of 0.080 and 0.093, respectively. Agreement with the expert rater was 22.2% at T1 and 20.4% at T2, with weighted kappa values of 0.170 and 0.127.Conclusion: A short lecture-based training is insufficient for reliable NBI interpretation by novice raters. These findings support the necessity for structured, competency-based training and supervised case libraries before Takano-based NBI assessment can be recommended in clinical practice for inexperienced practitioners.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Collaborative Networks as a Pathway to Stronger Scientific Evidence in Oral Pathology/Medicine in Latin America. 协作网络是拉丁美洲口腔病理学/医学获得更有力科学证据的途径。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-04-26 DOI: 10.1111/odi.70356

Bruno Augusto Benevenuto de Andrade, Luiz Miguel Ferreira, Daniella Reis B Martelli, Gerardo Marcelo Gilligan, Hercílio Martelli-Júnior

引用次数: 0

Eosinophilic Sialodochitis: A Review of the Literature. 嗜酸性粒细胞性涎腺炎：文献综述。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-04-26 DOI: 10.1111/odi.70341

Soulafa Almazrooa

{"title":"Eosinophilic Sialodochitis: A Review of the Literature.","authors":"Soulafa Almazrooa","doi":"10.1111/odi.70341","DOIUrl":"https://doi.org/10.1111/odi.70341","url":null,"abstract":"Objective: Eosinophilic sialodochitis is an uncommon, chronic inflammatory disorder of the major salivary glands characterized by intermittent pain, swelling, and mucous plugging containing eosinophils. Despite increasing reports, optimal diagnostic criteria and management remain unclear.Methods: PubMed, ScienceDirect, Google Scholar, and Ovid databases were searched to August 2025. Data were collected from eligible studies published after 2000 in English, noting that some significant reviews also summarize the Japanese literature.Results: Twenty-four studies (n = 309 patients) were included. The mean age was 39 years, with a male: female ratio of 1:2.5. The parotid gland was most often affected (50.8%), with bilateral involvement in 43.4% of cases. Most patients (87.4%) had atopy, particularly allergic rhinitis (75.4%). Swelling (94.5%), mucous plugs (46.0%), and pain (24.6%) were the most common symptoms. IgE was elevated in 66.3%, peripheral eosinophilia in 36.0%, and both in 6.5%. Imaging revealed ductal ectasia and stenosis, while histopathology demonstrated periductal fibrosis and eosinophilic infiltration. Endoscopy-assisted ductal irrigation and dilation were the most effective treatments, followed by conservative surgical excision. Medical treatments such as antihistamines, corticosteroids, and leukotriene receptor antagonists achieved variable treatment success.Conclusions: Future multicenter studies may eventually establish a definitive diagnostic algorithm based on combinations of clinical findings, IgE/eosinophils, and imaging.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tongue Nodule Affecting Breastfeeding. 影响母乳喂养的舌结节。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-04-24 DOI: 10.1111/odi.70283

Giuliano Saraceni Issa Cossolin, Heitor Albergoni Silveira, Ana Paula Abreu Vieira Alves, Carla Gabriela Ermacora, José Burgos Ponce, Camila Lopes Cardoso

引用次数: 0

Squamous Odontogenic Tumor: A Systematic Review. 牙源性鳞状肿瘤：系统综述。

IF 2.9 3区医学

Oral diseases Pub Date : 2026-04-24 DOI: 10.1111/odi.70340

Paula Sousa Lopes de Cascaes, Licia Pacheco Teixeira, Andresa Borges Soares, Izabel Regina Fischer Rubira-Bullen, Monikelly Carmo Narchini do Nascimento, José Luiz Cintra Junqueira, Mariana Quirino Silveira Soares

{"title":"Squamous Odontogenic Tumor: A Systematic Review.","authors":"Paula Sousa Lopes de Cascaes, Licia Pacheco Teixeira, Andresa Borges Soares, Izabel Regina Fischer Rubira-Bullen, Monikelly Carmo Narchini do Nascimento, José Luiz Cintra Junqueira, Mariana Quirino Silveira Soares","doi":"10.1111/odi.70340","DOIUrl":"https://doi.org/10.1111/odi.70340","url":null,"abstract":"Objective: Squamous odontogenic tumor is a rare benign epithelial odontogenic neoplasm whose overlapping features with other odontogenic lesions may hinder diagnosis and management. This systematic review analyzed clinical, radiographic, histopathological characteristics and treatment outcomes of SOT.Methods: Comprehensive search was conducted in April 2025 across PubMed, Web of Science, Scopus, Embase, Cochrane Library, Livivo, BVS, SciELO, ProQuest, OpenGrey, IBICT/BDTD, and Google Scholar. Two independent reviewers performed study selection, data extraction, and risk-of-bias assessment. Only cases fulfilling diagnostic criteria established by the WHO Classification of Head and Neck Tumors (2024) were included. Cases descriptions and images were assessed by an experienced oral pathologist to confirm diagnostic consistency.Results: A total of 65 SOT lesions were identified, including 59 intraosseous and 6 peripheral cases. Intraosseous lesions occurred across a wide age range with slight male predominance. Most lesions were solitary and located in the maxilla or posterior jaw regions. Radiographically, intraosseous lesions were predominantly unilocular, with triangular configuration most frequently reported. Most lesions were treated with conservative surgery, particularly surgical excision, and recurrence occurred in a minority of intraosseous cases. Peripheral lesions were solitary and showed a benign course without recurrence.Conclusion: SOT generally presents as a benign lesion with a favorable prognosis.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0