Oral diseasesPub Date : 2025-03-18DOI: 10.1111/odi.15314
Rebeka Thiara Nascimento Dos Santos, Jonathan França da Silva Cavalcanti, Luiz Gustavo de Sousa Duda Júnior, Ana Júlia Alves de Vasconcelos, Pamella Recco Alvares, Ana Paula Veras Sobral
{"title":"Teleconsultation Actions in Reducing In-Person Referrals for Oral Lesions: A Scoping Review.","authors":"Rebeka Thiara Nascimento Dos Santos, Jonathan França da Silva Cavalcanti, Luiz Gustavo de Sousa Duda Júnior, Ana Júlia Alves de Vasconcelos, Pamella Recco Alvares, Ana Paula Veras Sobral","doi":"10.1111/odi.15314","DOIUrl":"https://doi.org/10.1111/odi.15314","url":null,"abstract":"<p><strong>Objectives: </strong>This scoping review aimed to investigate the impact of teleconsultation actions on the reduction of unnecessary referrals for specialized in-person care of oral lesions.</p><p><strong>Materials and methods: </strong>This review included studies on teleconsultation in oral medicine and oral pathology that presented data on the referral flow for in-person care. Teleconsultation modalities included synchronous, asynchronous, or unspecified interactions. Excluded from the review were: (1) reviews, clinical cases, letters, chapters, conference abstracts, and editorials; (2) studies on direct teleconsultation between professionals; (3) telemanagement interventions; and (4) tele-education initiatives.</p><p><strong>Results: </strong>Nine articles met the inclusion criteria. The asynchronous teleconsultation stands out as the most effective intervention for reducing in-person referrals, observed in eight studies. Referral reductions ranged from 37.3% to 80%, with five studies exceeding 50%. Primary healthcare dentists were the most frequent users of the teleconsultation platform. The most commonly identified lesions found were oral potentially malignant disorders and soft tissue tumors.</p><p><strong>Conclusion: </strong>Asynchronous teleconsultation may reduce referrals for in-person care, though evidence is limited. Notably, referral rates exhibited significant heterogeneity across studies. Low reduction rates may be attributed to the high proportion of cases requiring in-person assessment. Future research should focus on optimizing referral reduction while addressing the heterogeneity of outcomes.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-17DOI: 10.1111/odi.15311
Shivani Shah, Nila Veerabagu, Nana A A Essel, Neda Mahjour, Katherine France
{"title":"The Dental Status of Patients Taking Common Biologic Agents: A Single-Center Cross-Sectional Study.","authors":"Shivani Shah, Nila Veerabagu, Nana A A Essel, Neda Mahjour, Katherine France","doi":"10.1111/odi.15311","DOIUrl":"https://doi.org/10.1111/odi.15311","url":null,"abstract":"<p><strong>Objectives: </strong>Despite expanding use and medical applications, little is known about the impact of biologic agents (BAs) on dental treatment. The aim of this study was to investigate the dental status of patients on common classes of BAs to understand treatment needs and use in this population.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted on patients treated with the most common classes of BA (tumor necrosis factor-alpha [TNF-α] inhibitors, interleukin (IL) inhibitors, and lymphocyte modulators) from 1/7/2017 to 1/7/2022. Data on demographic factors, BA treatment, medical conditions including indication, restorative and periodontal treatments, and decayed, missing, and filled tooth index (DMFT) were compared descriptively.</p><p><strong>Results: </strong>The study identified 247 patients treated with 24 different BAs. Restorative and periodontal treatment was completed on 60.3% and 72.9% of patients, respectively. The DMFT scores were higher in the study cohort compared to the average US adult population. The analysis revealed an upward trend in both periodontal and restorative treatments.</p><p><strong>Conclusions: </strong>This study provides the first comprehensive characterization of the oral health status and treatment needs of patients taking BAs. The findings suggest a higher dental treatment burden in this population, particularly regarding restorative care in this population, a finding that may be confirmed or expanded in future evaluations.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-17DOI: 10.1111/odi.15302
Daniele Sorgatto Faé, Francielle Silvestre Verner, Cleidiel Aparecido Araujo Lemos, Rafael Binato Junqueira, Rodrigo Furtado de Carvalho, Pedro Henrique Berbert de Carvalho, Sibele Nascimento de Aquino
{"title":"Development of the Multidimensional Scale Related to Infectious Diseases in Dentistry.","authors":"Daniele Sorgatto Faé, Francielle Silvestre Verner, Cleidiel Aparecido Araujo Lemos, Rafael Binato Junqueira, Rodrigo Furtado de Carvalho, Pedro Henrique Berbert de Carvalho, Sibele Nascimento de Aquino","doi":"10.1111/odi.15302","DOIUrl":"https://doi.org/10.1111/odi.15302","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to develop and validate an instrument to assess dentists' adherence to infection control protocols and explore psychological factors related to infectious diseases in dental practice.</p><p><strong>Materials and methods: </strong>The instrument was developed through phases including context validity, face and semantic analysis, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA). Internal consistency was evaluated using McDonald's Omega coefficient (ω) and Cronbach's Alpha (α).</p><p><strong>Results: </strong>A total of 405 individuals completed the instrument. EFA (n = 135) revealed a four-factor structure (Work Environmental Protection, Disinfection, Team Training, and Fear and Anxiety) with 23 items with factor loadings above 0.60. The Kaiser-Meyer-Olkin (KMO) value was 0.803, and Bartlett's test of sphericity was significant (χ<sup>2</sup>: 2501.136, df:253.000, p < 0.001). CFA (n = 270) confirmed an acceptable model fit: χ<sup>2</sup>/df: 1.75; Comparative Fit Index (CFI): 0.997; Tucker-Lewis Index (TLI): 0.996; Standardized Root Mean Square Residual (SRMR): 0.079; Root Mean Square Error of Approximation (RMSEA): 0.053, supporting the four-factor structure from the EFA. Reliability analysis demonstrated strong internal consistency across all factors (ω and α ≥ 0.70).</p><p><strong>Conclusion: </strong>The developed instrument exhibited appropriate validity, reliability, and internal consistency, providing a suitable tool to evaluate infection control adherence and psychological aspects among dentists facing infectious diseases.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-17DOI: 10.1111/odi.15303
Ruijie Jiao, Hu Long
{"title":"Ferroptosis: A New Challenge and Target in Oral Diseases.","authors":"Ruijie Jiao, Hu Long","doi":"10.1111/odi.15303","DOIUrl":"https://doi.org/10.1111/odi.15303","url":null,"abstract":"<p><strong>Objective: </strong>Ferroptosis, an iron-dependent intracellular programmed cell death mechanism discovered in the last decade, has emerged as a novel and intriguing concept in oral diseases, distinct from apoptosis, necrosis, and pyroptosis. This process plays a critical role in the pathophysiology of inflammation, trauma, and tumors, with evidence of its presence in multiple organ systems, including the liver, kidneys, and heart. In recent years, many studies have found that ferroptosis is closely related to oral diseases, and a number of pathogenic pathways and therapeutic strategies have been reported. However, ferroptosis remains an underexplored area in oral diseases, with multiple secrets waiting to be uncovered.</p><p><strong>Method: </strong>We collected articles related to ferroptosis and oral diseases and analyzed the mechanisms and therapeutic strategies associated with ferroptosis in different oral diseases.</p><p><strong>Results: </strong>In this review, we present a comprehensive analysis of ferroptosis and oral diseases, emphasizing its core mechanisms and associated therapeutic approaches. Furthermore, we give an outlook for future explorations of ferroptosis related to oral diseases.</p><p><strong>Conclusion: </strong>This review provides dental researchers and clinicians with a current state of ferroptosis in oral diseases, thereby inspiring noval investigations and discoveries.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-17DOI: 10.1111/odi.15315
Luiz Miguel Ferreira, Marcos Paulo Maia-Lima, Samuel Trezena, Fabrício Emanuel Soares de Oliveira, Árlen Almeida Duarte, Daniella Reis Barbosa Martelli, Fábio de Abreu Alves, Roseana de Almeida Freitas, Jean Nunes Dos Santos, Maria Cassia Ferreira de Aguiar, Marcio Ajudarte Lopes, Paulo Rogério Ferreti Bonan, Janete Dias Almeida, Hercílio Martelli-Júnior
{"title":"Postgraduate Satisfaction in Oral Pathology and Oral Medicine: Insights From Brazil.","authors":"Luiz Miguel Ferreira, Marcos Paulo Maia-Lima, Samuel Trezena, Fabrício Emanuel Soares de Oliveira, Árlen Almeida Duarte, Daniella Reis Barbosa Martelli, Fábio de Abreu Alves, Roseana de Almeida Freitas, Jean Nunes Dos Santos, Maria Cassia Ferreira de Aguiar, Marcio Ajudarte Lopes, Paulo Rogério Ferreti Bonan, Janete Dias Almeida, Hercílio Martelli-Júnior","doi":"10.1111/odi.15315","DOIUrl":"https://doi.org/10.1111/odi.15315","url":null,"abstract":"","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-17DOI: 10.1111/odi.15313
Mary Anne de Souza Alves França, Rejane Faria Ribeiro-Rotta, Nádia do Lago Costa, Patrícia Corrêa-Faria, Gabriela Moreira Policena, Maria do Carmo Matias Freire
{"title":"Time to Treatment Initiation of Oral Cancer: Impact of a National Policy in Midwest Brazil.","authors":"Mary Anne de Souza Alves França, Rejane Faria Ribeiro-Rotta, Nádia do Lago Costa, Patrícia Corrêa-Faria, Gabriela Moreira Policena, Maria do Carmo Matias Freire","doi":"10.1111/odi.15313","DOIUrl":"https://doi.org/10.1111/odi.15313","url":null,"abstract":"","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-14DOI: 10.1111/odi.15306
Julie Toby Thomas, Betsy Joseph, Sukumaran Anil, Tuomas Waltimo, Timo Sorsa
{"title":"Authors' Reply: \"Association Between Metabolic Syndrome and Salivary MMP-8, MPO in Periodontitis\".","authors":"Julie Toby Thomas, Betsy Joseph, Sukumaran Anil, Tuomas Waltimo, Timo Sorsa","doi":"10.1111/odi.15306","DOIUrl":"https://doi.org/10.1111/odi.15306","url":null,"abstract":"","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-14DOI: 10.1111/odi.15268
Bo Lin, Feng Wang, Shiyue Shen, Yufan Wang, Xia Hong, Xin Ye, Shunji Wang, Youdan Yao, Tianwen Zhang, Huijun Yang, Hongyu Yang
{"title":"Imaging and Pathology Concordance in Head and Neck Cancer: Retrospective Analysis.","authors":"Bo Lin, Feng Wang, Shiyue Shen, Yufan Wang, Xia Hong, Xin Ye, Shunji Wang, Youdan Yao, Tianwen Zhang, Huijun Yang, Hongyu Yang","doi":"10.1111/odi.15268","DOIUrl":"https://doi.org/10.1111/odi.15268","url":null,"abstract":"<p><strong>Background: </strong>Lymph node metastasis critically impacts prognosis in head and neck malignancies. Preoperative imaging (CT/MRI) is vital for assessment but often yields false results. This study examines the concordance between preoperative imaging and postoperative pathology and identifies factors influencing imaging accuracy.</p><p><strong>Methods: </strong>A retrospective cohort study from 2014 to 2023 included patients with head and neck malignancies. Clinical and radiological data were analyzed, and the random forest algorithm was utilized for indeterminate cases.</p><p><strong>Results: </strong>Analyzing 1129 records, 26.1% had indeterminate imaging. Imaging accuracy for definitive findings was 72.8%, sensitivity 57.2%, and specificity 86.0%. Logistic regression highlighted alcohol, T, and clinical stage as accuracy influencers. The indeterminate group showed a link between multiple enlarged lymph nodes and positivity. A nomogram achieved 67.5% accuracy. The random forest model, focusing on lymph node diameter, stage, and T classification, improved accuracy to 75.5% over logistic regression.</p><p><strong>Conclusion: </strong>Our study shows moderate imaging-pathology concordance. Key predictors like lymph node size suggest refining criteria with machine learning could enhance head and neck cancer diagnosis. These results could guide more accurate preoperative imaging assessments, leading to better surgical planning and patient outcomes. Subsequent exploration of adjusting lymph node size thresholds or integrating novel imaging technologies would be useful.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-14DOI: 10.1111/odi.15310
Büşra Yılmaz, Hüseyin Sagman, Timur Köse, Gülnur Emingil
{"title":"Transgender Individuals in the Eyes of Dental Professionals: A Data-Driven Study.","authors":"Büşra Yılmaz, Hüseyin Sagman, Timur Köse, Gülnur Emingil","doi":"10.1111/odi.15310","DOIUrl":"https://doi.org/10.1111/odi.15310","url":null,"abstract":"<p><strong>Objectives: </strong>Transgender individuals continue to face discrimination, particularly in accessing oral healthcare. This study aimed to evaluate dentists' attitudes toward transgender people and their knowledge of gender-affirming care.</p><p><strong>Materials and methods: </strong>A questionnaire assessing demographic data, clinical approaches, and knowledge of gender-affirming care was distributed via social media, professional chambers, and associations. Descriptive statistics were analyzed using SPSS, with Chi-square and Fisher exact tests, alongside logistic regression for appropriate questions.</p><p><strong>Results: </strong>A total of 403 dentists participated, with 8% reporting professional prejudices against transgender individuals. Dentists who associated transgender patients with increased clinical infection rates were statistically more likely to hold prejudices (p < 0.05). Additionally, 60.2% expressed interest in training to enhance communication with transgender patients. Female dentists were significantly more likely to be open to such training (p < 0.05).</p><p><strong>Conclusion: </strong>The findings highlight a strong desire among dentists for training to improve communication with transgender patients, along with a lack of knowledge about key topics such as gender-affirming, endogenous hormones, and their oral health implications. This underscores the need for targeted educational initiatives in the dental community.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-03-14DOI: 10.1111/odi.15312
Felippe José Almeida Loureiro, Karolyny Martins Balbinot, Maria Sueli da Silva Kataoka, Hellen Thais Fuzii, Sérgio de Melo Alves Júnior, José Antônio Picanço Diniz Júnior, Felipe Tuji de Castro Franco, João de Jesus Viana Pinheiro
{"title":"Invadopodia Related-Proteins Expression in Mucoepidermoid Carcinoma.","authors":"Felippe José Almeida Loureiro, Karolyny Martins Balbinot, Maria Sueli da Silva Kataoka, Hellen Thais Fuzii, Sérgio de Melo Alves Júnior, José Antônio Picanço Diniz Júnior, Felipe Tuji de Castro Franco, João de Jesus Viana Pinheiro","doi":"10.1111/odi.15312","DOIUrl":"https://doi.org/10.1111/odi.15312","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the expression of invadopodia-related proteins in mucoepidermoid carcinoma and their influence on this tumor's invasiveness.</p><p><strong>Material and methods: </strong>Twenty-seven mucoepidermoid carcinoma grading samples were evaluated for the expression of Tks4, Tks5, cortactin, and MT1-MMP and compared to 10 control samples of normal-looking salivary glands by immunohistochemistry. For in vitro analysis, immunofluorescence identified the expression of invadopodia-related proteins in the mucoepidermoid carcinoma cell line. Invadopodia formation and invasion assays were performed after silencing of Tks4 and Tks5 to evaluate invasiveness.</p><p><strong>Results: </strong>The invadopodia-related proteins were expressed significantly higher in mucoepidermoid carcinoma samples when compared to the control group. Positive expression of these proteins was identified in the mucoepidermoid carcinoma cell line. Knockdown of Tks4 and Tks5 reduced both gelatin degradation and invadopodia activity in mucoepidermoid carcinoma cell lines.</p><p><strong>Conclusion: </strong>Our results suggest that mucoepidermoid carcinoma behavior can be mediated by the expression of invadopodia-related proteins. Tks4 and Tks5 play a role in the invasiveness of mucoepidermoid carcinoma, mediated by invadopodia.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}