Oral diseases最新文献_第10页

Emergency of oral haemorrhage: Retrospective study over 2 years. 口腔出血急诊：历时两年的回顾性研究

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-10-07 DOI: 10.1111/odi.15137

M Pinana, I Rodriguez-Perron, G Lescaille, R Toledo, M Mondoloni, J Rochefort

{"title":"Emergency of oral haemorrhage: Retrospective study over 2 years.","authors":"M Pinana, I Rodriguez-Perron, G Lescaille, R Toledo, M Mondoloni, J Rochefort","doi":"10.1111/odi.15137","DOIUrl":"10.1111/odi.15137","url":null,"abstract":"Introduction: Oral haemorrhages (OH) represent a relatively rare reason for an emergency consultation, among dental pain, infectious processes and traumas. Various haemorrhagic risk factors are described, particularly those related to a general medical context or local factors. It is common to associate OH with haemorrhagic risk patients. Current studies mainly focus on patients considered at risk, but there is limited data on the characteristics of OH in patients without known haemorrhagic risk.Method: We conducted a 2-year retrospective study in a dental emergency department to identify OH occurring in patients without known haemorrhagic risk and to study their characteristics.Results: OH accounted for approximately 2% of the reasons for consultation among all consultations carried out for dental emergencies. Their frequency was similar in the population of patients without hemorrhagic risk and those with a confirmed risk. They mainly occurred in young patients, without medical history. They also led to the diagnosis of an underlying pathology in about 1% of cases.Conclusion: This study underscores the importance of accurately documenting patients' medical history during preoperative consultations, as well as identifying associated risk factors. It also highlights that OH can be an early sign of a systemic disorder.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"648-655"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aerosolized e-liquid base constituents induce cytotoxicity and genotoxicity in oral keratinocytes. 气溶胶电子液体基质成分会诱导口腔角质细胞产生细胞毒性和遗传毒性。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-08-09 DOI: 10.1111/odi.15104

Tao Ma, Angela Lee, Bryan Eng, Vyomesh Patel, Sarah L J Michel, Maureen A Kane, Richard Dalby, Abraham Schneider

{"title":"Aerosolized e-liquid base constituents induce cytotoxicity and genotoxicity in oral keratinocytes.","authors":"Tao Ma, Angela Lee, Bryan Eng, Vyomesh Patel, Sarah L J Michel, Maureen A Kane, Richard Dalby, Abraham Schneider","doi":"10.1111/odi.15104","DOIUrl":"10.1111/odi.15104","url":null,"abstract":"Objective: Electronic cigarette (e-cigarette) use among adults in the United States continues to rise. Particularly concerning is the impact of e-cigarette aerosol inhalation on the oral mucosa. Aerosols are derived from a heated e-liquid base of propylene glycol/glycerin (PG/G) often mixed with nicotine and chemical flavors. Of note, harmful and potentially harmful constituents (HPHCs), including metals and volatile organic compounds, have been detected in e-cigarette aerosols. It remains unknown, however, whether aerosols exclusively derived from e-liquid PG/G are detrimental to oral keratinocytes. The present study analyzed toxicological outcomes in normal oral keratinocytes exposed to model nicotine-free, unflavored PG/G e-liquid aerosols.Materials and methods: Cell viability/cytotoxicity, genotoxicity, and immunoblotting assays were conducted in NOKSI, a gingiva-derived oral keratinocyte cell line, following exposure to model e-liquid aerosols or non-aerosolized controls. The HPHC acrolein, reported to form DNA adducts in the buccal mucosa from e-cigarette users, was also used in similar assays.Results: PG/G e-liquid aerosol extracts significantly enhanced cytotoxic and DNA damaging responses in NOKSI cells when compared to non-aerosolized e-liquid treatment. Acrolein treatment led to similar results.Conclusions: The aerosolization process of PG/G e-liquid is a critical determinant of marked cytotoxic and genotoxic stimuli in oral keratinocytes.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"482-491"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141910028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can high-power lasers photobiomodulation therapy alleviate the pain of refractory oral mucositis? 高功率激光光生物调节疗法能否减轻难治性口腔黏膜炎的痛苦？

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-08-20 DOI: 10.1111/odi.15112

Qian Wang, Jianqiu Jin

引用次数: 0

Immunohistochemical Evaluation of p300, H2AacK5 and H3AcK27 in Odontogenic Cysts and Tumors. 牙源性囊肿和肿瘤中 p300、H2AacK5 和 H3AcK27 的免疫组化评估

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-10-22 DOI: 10.1111/odi.15164

Luciane De Jesus Carvalho, Douglas Magno Guimarães, Alann Thaffarell Portilho Souza, Karolyny Martins Balbinot, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Junior, Fabio Daumas Nunes, Marcos José Custódio Neto da Silva, João de Jesus Viana Pinheiro

{"title":"Immunohistochemical Evaluation of p300, H2AacK5 and H3AcK27 in Odontogenic Cysts and Tumors.","authors":"Luciane De Jesus Carvalho, Douglas Magno Guimarães, Alann Thaffarell Portilho Souza, Karolyny Martins Balbinot, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Junior, Fabio Daumas Nunes, Marcos José Custódio Neto da Silva, João de Jesus Viana Pinheiro","doi":"10.1111/odi.15164","DOIUrl":"10.1111/odi.15164","url":null,"abstract":"The acetylation of histones H2A on lysine 5 (H2AacK5) and H3 on lysine 27 (H3AcK27) modulate several cellular mechanisms through the p300 enzyme in pathological lesions; however, their role in odontogenic lesions has not been addressed. This study aims to evaluate the immunoexpression of p300, H2AacK5, and H3AcK27 in samples of ameloblastoma (AMB) (n = 30), odontogenic keratocyst (OK) (n = 15), adenomatoid odontogenic tumor (AOT) (n = 10), odontogenic fibroma (OF) (n = 8), calcifying odontogenic cyst (COC) (n = 8), odontogenic myxoma (MIX) (n = 10), and ameloblastic fibroma (AF) (n = 06). The percentage of p300-positive cells was higher in AOT and decreased in COC, OK, AMB, AF, OF, and MIX. H2AacK5-positive cells were higher in AF and decreased in AOT, COC, OK, OF, AMB, and MIX, whereas H3acK27-positive cells were higher in AOT and decreased in COC, OK, AF, OF, AMB, and MIX. The expression of these proteins was higher in nonaggressive lesions in comparison to aggressive lesions. There was a positive correlation between p300 and H2AacK5, and H3acK27 in AMB, MIX, and OF, whereas there was a positive correlation between p300 and H2AacK5 in AOT and COC. The histone acetylation may be involved in the biological behavior of these lesions, which could be used to improve their diagnosis and treatment.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"555-564"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body Mass Index as an Indicator of Survival in Oral Cancer. 作为口腔癌生存指标的体重指数

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-10-14 DOI: 10.1111/odi.15155

Deysimara de Cássia Santos, Gisele Queiroz Carvalho, Carina Carvalho Silvestre, Sibele Nascimento de Aquino

引用次数: 0

Authors' reply: "MRTF-A/SRF signaling suppresses invasion of oral squamous cell carcinoma". 作者的回复："MRTF-A/SRF信号抑制口腔鳞状细胞癌的侵袭

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-07-24 DOI: 10.1111/odi.15091

Dan Yang, Hongxia Dan

引用次数: 0

Epidemiological Features of 4777 Cysts and Odontogenic Tumors Based on the 2022 WHO Classification. 基于 2022 年世界卫生组织分类的 4777 例囊肿和牙源性肿瘤的流行病学特征。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-10-06 DOI: 10.1111/odi.15146

Victoria Rees, Matías Klare, Valentina Samaniego, Felipe Leiva, René Jara, Benjamín Martínez Rondanelli, Sergio González Providell

{"title":"Epidemiological Features of 4777 Cysts and Odontogenic Tumors Based on the 2022 WHO Classification.","authors":"Victoria Rees, Matías Klare, Valentina Samaniego, Felipe Leiva, René Jara, Benjamín Martínez Rondanelli, Sergio González Providell","doi":"10.1111/odi.15146","DOIUrl":"10.1111/odi.15146","url":null,"abstract":"Objective: The epidemiology of cysts and odontogenic tumors is important for differential diagnosis and treatment strategies. We aimed to describe the epidemiological features of cysts and odontogenic tumors in the Chilean population using the current WHO classification.Materials and methods: We reviewed 22,914 biopsy requests received between January 1984 and September 2023 at the oral pathology department, School of Dentistry, Universidad Mayor, Santiago, Chile. Patients diagnosed with cysts of the jaws and odontogenic tumors were selected and information regarding age, sex, and location was recorded.Results: 4226 (18.4%) were cysts, and 551 (2.4%) were odontogenic tumors, ranging from 2 to 97 years old. Males represented 54.4% and females 45.7% of the total sample. The most prevalent cysts were radicular cysts (58.6%), dentigerous cysts (17.9%), and odontogenic keratocysts (13.3%). The most prevalent odontogenic tumors were odontomas (40.1%) and conventional ameloblastoma (17.6%).Conclusions: Our study was the first retrospective analysis to determine the epidemiological features of both cysts and odontogenic tumors together, based on the 2022 WHO classification. This is relevant as it offers a potential basis for comprehensive comparisons of the epidemiological features of these entities, which could contribute to an accurate differential diagnosis, therefore, leading to more effective therapeutic interventions.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"532-540"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Oral Frailty on Postoperative Infection in Patients Undergoing Abdominal Visceral Surgery. 口腔虚弱对腹部内脏手术患者术后感染的影响

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-10-16 DOI: 10.1111/odi.15162

Tamao Ikuno, Mitsuru Ida, Yoshihiro Momota, Masahiko Kawaguchi

{"title":"Effect of Oral Frailty on Postoperative Infection in Patients Undergoing Abdominal Visceral Surgery.","authors":"Tamao Ikuno, Mitsuru Ida, Yoshihiro Momota, Masahiko Kawaguchi","doi":"10.1111/odi.15162","DOIUrl":"10.1111/odi.15162","url":null,"abstract":"Objectives: To assess effects of the oral frailty index-8 (OFI-8) on the incidence of postoperative infection.Subjects and methods: This retrospective study included patients aged ≥ 65 years who underwent elective abdominal visceral surgery under general anaesthesia. Oral frailty was assessed using OFI-8 (total score, 0-11), with higher scores indicating poorer oral health. The primary outcome measure was incidence of postoperative infection. The association between incidence of postoperative infection and OFI-8 score was evaluated using multiple logistic regression analysis adjusted for clinically relevant preoperative and intraoperative covariates.Results: Data of 791 patients (mean age, 74 years; mean OFI-8 score, 3.4) were analysed. The OFI-8 score had a linear association (P for nonlinear effect on postoperative infection = 0.43) with a composite postoperative infection at a rate of 14.2% (95% confidence interval: 11.8-16.7). The adjusted odds ratio of the OFI-8 score for the primary outcome was 1.10 (95% confidence interval: 1.00-1.21), indicating that patients with higher OFI-8 scores tended to have postoperative infections.Conclusion: This study's findings suggest that patients with higher OFI-8 scores were more likely to develop postoperative infection after undergoing elective abdominal visceral surgery.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"633-639"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive profile in burning mouth syndrome versus mild cognitive impairment: A comparative study. 灼口综合征与轻度认知障碍的认知概况：比较研究

IF 2.9 3区医学

Oral diseases Pub Date : 2025-02-01 Epub Date: 2024-07-30 DOI: 10.1111/odi.15087

Grazia Daniela Femminella, Federica Canfora, Gennaro Musella, Gianluca Scotto Di Tella, Lorenzo Ugga, Giuseppe Pecoraro, Stefania Leuci, Noemi Coppola, Natascia De Lucia, Nelson Mauro Maldonato, Simone Liguori, Massimo Aria, Luca D'Aniello, Giuseppe Rengo, Michele Davide Mignogna, Daniela Adamo

{"title":"Cognitive profile in burning mouth syndrome versus mild cognitive impairment: A comparative study.","authors":"Grazia Daniela Femminella, Federica Canfora, Gennaro Musella, Gianluca Scotto Di Tella, Lorenzo Ugga, Giuseppe Pecoraro, Stefania Leuci, Noemi Coppola, Natascia De Lucia, Nelson Mauro Maldonato, Simone Liguori, Massimo Aria, Luca D'Aniello, Giuseppe Rengo, Michele Davide Mignogna, Daniela Adamo","doi":"10.1111/odi.15087","DOIUrl":"10.1111/odi.15087","url":null,"abstract":"Objectives: This study aims to assess and contrast cognitive and psychological aspects of patients with burning mouth syndrome (BMS-MCI) and geriatric patients (G-MCI) with mild cognitive impairment, focusing on potential predictors like pain, mood disorders, blood biomarkers, and age-related white matter changes (ARWMCs).Methods: The study enrolled 40 BMS-MCI and 40 geriatric G-MCI, matching them by age, gender, and educational background. Participants underwent psychological, sleepiness, and cognitive assessment including the Mini-Mental State Exam (MMSE), Trail Making Test (TMT), Corsi Block-Tapping Task, Rey Auditory Verbal Learning Test, Copying Geometric Drawings Test, Frontal Assessment Battery, and Digit Cancellation Test.Results: G-MCI patients exhibited higher ARWMCs scores in right (p = 0.005**) and left (p < 0.001**) temporal regions, which may relate to specific neurodegenerative processes. Conversely, BMS-MCI patients showed higher levels of depression and anxiety and lower MMSE scores(p < 0.001**), also struggling more with tasks requiring processing speed and executive function, as evidenced by their higher TMT-A scores (p < 0.001**).Conclusions: The study highlights particular deficits in global cognition and processing speed for BMS-MCI. The influence of educational background, pain levels, cholesterol, sleep disturbances, and anxiety on these cognitive assessments underscores the need for personalized therapeutic strategies addressing both cognitive and emotional aspects of MCI.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"611-632"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awake Bruxism Is Unrelated to Smoking, Despite the Different Psychological Status: A Pilot Study.

IF 2.9 3区医学

Oral diseases Pub Date : 2025-01-30 DOI: 10.1111/odi.15270

Ovidiu Ionut Saracutu, Daniele Manfredini, Alessandro Bracci, Marco Ferrari, Edoardo Ferrari Cagidiaco, Anna Colonna, Matteo Pollis

{"title":"Awake Bruxism Is Unrelated to Smoking, Despite the Different Psychological Status: A Pilot Study.","authors":"Ovidiu Ionut Saracutu, Daniele Manfredini, Alessandro Bracci, Marco Ferrari, Edoardo Ferrari Cagidiaco, Anna Colonna, Matteo Pollis","doi":"10.1111/odi.15270","DOIUrl":"https://doi.org/10.1111/odi.15270","url":null,"abstract":"Objective: The aim of the present study is to get deeper into the complex interplay that might exist between awake bruxism (AB), tobacco smoking, and anxiety and/or depression symptoms in a group of healthy young adults.Materials and methods: The study participants were recruited by advertising the investigation at the University of Siena, Siena, Italy. The inclusion criteria were being in good general health, without systemic diseases or oral diseases. People with ongoing medical or dental treatment and those with a history of systemic disease or temporomandibular disorders were excluded. The participants who were included in the study received a questionnaire containing three sections for the assessment of AB behaviors, anxiety and depression symptoms, and the number of cigarettes smoked.Results: A total of 141 healthy young adults met the inclusion criteria. Different awake masticatory muscle activities showed different strengths of association with anxiety and depression symptoms. However, no relationship was found between the number of smoked cigarettes and the frequency of the various masticatory muscle activities considered.Conclusions: The result of the present study shows no clear-cut association between the frequency of self-reported AB behaviors and smoking in healthy individuals.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0