Oral diseases最新文献_第10页

Evaluation of Periodontal Viruses in Valvular Heart Disease. 评估瓣膜性心脏病中的牙周病毒

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-01 DOI: 10.1111/odi.15187

Paavai Ilango, Sanjay M Cherian, B Sivapathasundharam, Arulpari Mahalingam, Ayswarya V Vummidi, Vineela Katam Reddy, K M Cherian

引用次数: 0

Granuloma Faciale-Like Lesion of the Palate: A Previously Unreported Entity. 腭部面部肉芽肿样病变：一种以前从未报道过的实体瘤

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-03 DOI: 10.1111/odi.15180

Francesca Magnoli, Alessandro D'Aiuto, Cristina Ciardiello, Fabio Brusamolino, Michele Cerati, Lorenzo Azzi

引用次数: 0

Second Events After Curative-Intent Treatment for Lip Cancer: Navigating the Path of Follow-Up Care. 唇癌治愈性治疗后的第二次事件：引领后续护理之路。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-06 DOI: 10.1111/odi.15194

Fábio Muradás Girardi, Amanda de Farias Gabriel, Vivian Petersen Wagner, Manoela Domingues Martins

{"title":"Second Events After Curative-Intent Treatment for Lip Cancer: Navigating the Path of Follow-Up Care.","authors":"Fábio Muradás Girardi, Amanda de Farias Gabriel, Vivian Petersen Wagner, Manoela Domingues Martins","doi":"10.1111/odi.15194","DOIUrl":"10.1111/odi.15194","url":null,"abstract":"Objective: We aimed to investigate the pattern, risk, and treatment of subsequent events after curative-intent treatment of lip cancer.Methods: This retrospective cohort study included 313 patients treated for lip cancer from 2011 to 2021 in a tertiary oncological center.Results: After a median follow-up time of 29.16 months, 145 (46.32%) patients presented with second primary tumors, 93% of which were skin carcinomas. Locoregional recurrence occurred in 7.9% of cases, with 2.5% with nodal recurrence. The 1-, 5-, and 10-year cumulative second primary tumor probabilities were 32.8%, 60.92%, and 70.92%, respectively. A higher risk was observed in elderly patients and basal cell carcinoma cases located on the cutaneous surface of the upper lip. Regional metastasis but not second primary tumors negatively impacted survival.Conclusions: Our study helps fill a literature gap, structuring specific recommendations regarding evaluations and follow-up protocols for patients with lip cancer. Since cutaneous second primary tumors were the most common second event, standard skin examination is key. Age and histology were significant predictors for second primary tumors. For cases of locally advanced lip squamous cell carcinoma, standard guidelines for head and neck cancer must be followed.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"1189-1197"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features of Idiopathic Halitosis and Its Association With Low-Grade Systemic Inflammation. 特发性口臭的特征及其与低度系统性炎症的关系

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-10-27 DOI: 10.1111/odi.15173

Dan Ping Ruan, Ye Kan Li, Xiao Xian Qian

{"title":"Features of Idiopathic Halitosis and Its Association With Low-Grade Systemic Inflammation.","authors":"Dan Ping Ruan, Ye Kan Li, Xiao Xian Qian","doi":"10.1111/odi.15173","DOIUrl":"10.1111/odi.15173","url":null,"abstract":"Objectives: Idiopathic halitosis is occasionally encountered in clinical practice, yet with scarce reports. This work aimed to investigate its features and potential association with low-grade systemic inflammation (LGSI).Methods: This retrospective study reviewed idiopathic halitosis from 2469 halitosis patients and compared them with 63 healthy controls (HCs). Organoleptic score (OLS), exhaled volatile sulfur compounds (VSCs), serum inflammatory cytokines, and fractional exhaled nitric oxide (FeNO200) to indicate LGSI were determined.Results: Totally, 54 (2.19%) idiopathic halitosis patients were identified and they were extraoral. Dimethyl sulfide (DMS) was found to be the primary exhaled VSC. Inflammatory cytokines were slightly elevated in 5.56% (3/54) of idiopathic halitosis compared to none of HCs (p = 0.095). FeNO200 was elevated in 79.63% (43/54) of idiopathic halitosis compared to none of HCs (p < 0.001), with a sensitivity of 79.63% and specificity of 100% for the diagnosis of idiopathic halitosis. The FeNO200 level had positive correlations with OLS (r = 0.871) and DMS level (r = 0.485).Conclusion: Idiopathic halitosis is a rare condition which is closely associated with LGSI and possibly caused by unexplored extraoral pathologies. FeNO200 is recommended for its diagnosis with a high diagnostic power.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"1358-1364"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectrum of Craniofacial and Oral Malformations in China, a Multicenter Study. 中国颅面和口腔畸形谱系的多中心研究。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-27 DOI: 10.1111/odi.15207

Xiaohong Duan, Yulong Zhu, Shuguo Zheng, Yaling Song, Wenmei Wang, Dong Chen, Zhenjin Zhao, Yongchu Pan, Zhuo Chen, Tingting Zhang, Yongqing Huang, Liling Ren, Dandan Ma, Weihong Wang, Shengbin Huang, Qinggao Song, Baisheng Wang, Yan Zheng, Jiang Li, Jianhua Wang, Yanli Zhang, Xinyue Guo, Wenyan Ruan, Jing Wang, Zhongcheng Gong, Xiaofeng Chang, Zhenglin Yuan, Fu Wang, Guangqing Tian, Jing Meng, Zhexuan Bao, Lin Li

{"title":"Spectrum of Craniofacial and Oral Malformations in China, a Multicenter Study.","authors":"Xiaohong Duan, Yulong Zhu, Shuguo Zheng, Yaling Song, Wenmei Wang, Dong Chen, Zhenjin Zhao, Yongchu Pan, Zhuo Chen, Tingting Zhang, Yongqing Huang, Liling Ren, Dandan Ma, Weihong Wang, Shengbin Huang, Qinggao Song, Baisheng Wang, Yan Zheng, Jiang Li, Jianhua Wang, Yanli Zhang, Xinyue Guo, Wenyan Ruan, Jing Wang, Zhongcheng Gong, Xiaofeng Chang, Zhenglin Yuan, Fu Wang, Guangqing Tian, Jing Meng, Zhexuan Bao, Lin Li","doi":"10.1111/odi.15207","DOIUrl":"10.1111/odi.15207","url":null,"abstract":"Objective: Craniofacial and oral malformations (COMs) represent an important class of human developmental disorders with profound implications on the anatomical structure, appearance, and various physiological functions. In this study, we aimed to define the spectrum of COMs and analysis its features or possible influencing factors to improve the surveillance and control of the disease.Materials and methods: We organized a multicenter survey of COMs from 19 hospitals in 14 provinces. The clinical data of COM cases were collected from the electronic medical records system, cleaned and aggregated for analysis.Results: A total of 90,895 COM cases with 76 types of diseases were identified from 34,649,545 hospital population. The four most common COMs were supernumery teeth (62.64%), cleft lip and palate (28.53%), microdontia (2.86%), and tooth agenesis (1.70%). The remaining 72 diseases were detected in 3881 cases and were considered to be rare COMs. Moreover, 84.72% of rare COMs also manifested as other malformations or dysfunctions of the bone, skin and other tissues.Conclusions: COMs exhibit age and gender distribution patterns, have multiple types, and significant dental malformations. The diagnostic criteria and registration practices for COMs influence their reported prevalence and temporal trends, necessitating future improvements.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"1245-1254"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histone Lysine Lactylation (Kla)-induced BCAM Promotes OSCC Progression and Cis-Platinum Resistance. 组蛋白赖氨酸乳化（Kla）诱导的 BCAM 促进 OSCC 进展和顺铂抗性

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-06 DOI: 10.1111/odi.15179

Guangzhao Huang, Su Chen, Jialu He, Honglin Li, Zhongkai Ma, Grace Paka Lubamba, Lei Wang, Zhiyong Guo, Chunjie Li

{"title":"Histone Lysine Lactylation (Kla)-induced BCAM Promotes OSCC Progression and Cis-Platinum Resistance.","authors":"Guangzhao Huang, Su Chen, Jialu He, Honglin Li, Zhongkai Ma, Grace Paka Lubamba, Lei Wang, Zhiyong Guo, Chunjie Li","doi":"10.1111/odi.15179","DOIUrl":"10.1111/odi.15179","url":null,"abstract":"Objective: Histone lysine lactylation (Kla) plays a vital role in cancer progression. However, the prognostic value of histone Kla in oral squamous cell carcinoma (OSCC) remains unclear.Materials and methods: OSCC RNA expression data were obtained from the TCGA and GEO databases. We explored the prognostic value of histone Kla in OSCC via constructing a Cox model and determined the role of Kla in OSCC drug susceptibility and tumor microenvironment (TME). In addition, the biological roles of candidate biomarkers were identified.Results: A total of 1223 Kla-specific genes were obtained, with 228 DEKlaGs in OSCC. GO and KEGG enrichment analyses suggested that DEKlaGs contributed to inflammatory and cancer progression. A Cox model in accordance with BCAM, CGNL1, DGKG, and OLR1 could predict OSCC patient prognosis accurately. Subsequently, Kla-induced prognostic genes were identified to play a crucial role in OSCC drug therapy and TME. Moreover, BCAM was identified as a biomarker that promoted OSCC invasion, angiogenesis, and chemotherapy resistance.Conclusion: Kla was identified to be associated with OSCC prognosis, drug therapy, and TME. Histone Kla-induced BCAM was identified to play a crucial role during OSCC progression, suggesting that Kla is promising to be a novel therapeutic target for OSCC.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"1116-1132"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telediagnosis in Pediatric Stomatology: Impact on Referrals and Healthcare Network. 小儿口腔科的远程诊断：对转诊和医疗网络的影响。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-03 DOI: 10.1111/odi.15175

Michelle Roxo-Gonçalves, Pâmela de Souza Kargwanski, Ingrid Silva Santos, Caren Serra Bavaresco, Adriela Azevedo Souza Mariath, Marco Antonio Trevizani Martins, Manoela Domingues Martins, Roberto Nunes Umpierre, Vinicius C Carrard

引用次数: 0

Reply to Accurate Risk Prediction Model for Surgical Site Infection After Lower Third Molar Surgery. 回复 "下第三磨牙手术后手术部位感染的准确风险预测模型"。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-03 DOI: 10.1111/odi.15184

Akira Yamagami, Katsuya Narumi, Yoshitaka Saito, Ayako Furugen, Shungo Imai, Yoshimasa Kitagawa, Yoichi Ohiro, Ryo Takagi, Yoh Takekuma, Mitsuru Sugawara, Masaki Kobayashi

引用次数: 0

Extracellular Vesicles From LPS-Treated PDLSCs Induce NLRP3 Inflammasome Activation in Periodontitis. 脂多糖处理的PDLSCs细胞外囊泡诱导牙周炎NLRP3炎性体激活。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-12-09 DOI: 10.1111/odi.15210

Yeke Wu, Jiawei Li, Min Liu, Ranran Gao, Hongling Zhou, Qiongying Hu, Lixing Zhao, Yunfei Xie

{"title":"Extracellular Vesicles From LPS-Treated PDLSCs Induce NLRP3 Inflammasome Activation in Periodontitis.","authors":"Yeke Wu, Jiawei Li, Min Liu, Ranran Gao, Hongling Zhou, Qiongying Hu, Lixing Zhao, Yunfei Xie","doi":"10.1111/odi.15210","DOIUrl":"10.1111/odi.15210","url":null,"abstract":"Objective: This study aimed to investigate the effects of lipopolysaccharide (LPS)-pretreated primary periodontal ligament stem cell (PDLSC)-derived extracellular vesicles (EVs) (L-PDLSC-EVs) on periodontitis.Materials and methods: PDLSCs were obtained from mouse periodontal ligaments via enzymatic digestion. An in vitro inflammatory microenvironment for PDLSCs was established using LPS, and L-PDLSC-EVs were isolated through ultracentrifugation and identified. EVs from different treatments were co-incubated with RAW264.7 macrophages (Mφs) or periodontal ligament fibroblasts (PLFs) and their co-cultures, whereafter the biological behaviors in Mφs and PLFs were evaluated. Periodontitis mouse models were established to verify the role of L-PDLSC-EVs and the mechanisms involved.Results: There were no significant changes in the characteristics of L-PDLSC-EVs compared with control EVs. L-PDLSC-EVs promoted M1-type Mφ polarization and activated the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome. Furthermore, L-PDLSC-EVs promoted PLF cytotoxicity and apoptosis by enhancing the M1 polarization of Mφs. In periodontitis mouse models, L-PDLSC-EVs facilitated alveolar bone loss, PLF injury, and inflammatory responses, accompanied by an increased proportion of M1-type Mφs and reinforced NLRP3 inflammasome activation.Conclusions: L-PDLSC-EVs promoted PLF injury and exacerbated periodontitis through activating the NLRP3 inflammasome and promoting the polarization of M1-type Mφs, providing novel insights for the periodontitis progression.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"1277-1289"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automated Detection of Oral Malignant Lesions Using Deep Learning: Scoping Review and Meta-Analysis. 利用深度学习自动检测口腔恶性病变：范围综述与元分析》。

IF 2.9 3区医学

Oral diseases Pub Date : 2025-04-01 Epub Date: 2024-11-03 DOI: 10.1111/odi.15188

Olga Di Fede, Gaetano La Mantia, Marco Parola, Laura Maniscalco, Domenica Matranga, Pietro Tozzo, Giuseppina Campisi, Mario G C A Cimino

{"title":"Automated Detection of Oral Malignant Lesions Using Deep Learning: Scoping Review and Meta-Analysis.","authors":"Olga Di Fede, Gaetano La Mantia, Marco Parola, Laura Maniscalco, Domenica Matranga, Pietro Tozzo, Giuseppina Campisi, Mario G C A Cimino","doi":"10.1111/odi.15188","DOIUrl":"10.1111/odi.15188","url":null,"abstract":"Objective: Oral diseases, specifically malignant lesions, are serious global health concerns requiring early diagnosis for effective treatment. In recent years, deep learning (DL) has emerged as a powerful tool for the automated detection and classification of oral lesions. This research, by conducting a scoping review and meta-analysis, aims to provide an overview of the progress and achievements in the field of automated detection of oral lesions using DL.Materials and methods: A scoping review was conducted to identify relevant studies published in the last 5 years (2018-2023). A comprehensive search was conducted using several electronic databases, including PubMed, Web of Science, and Scopus. Two reviewers independently assessed the studies for eligibility and extracted data using a standardized form, and a meta-analysis was conducted to synthesize the findings.Results: Fourteen studies utilizing various DL algorithms were identified and included for the detection and classification of oral lesions from clinical images. Among these, three were included in the meta-analysis. The estimated pooled sensitivity and specificity were 0.86 (95% confidence interval [CI] = 0.80-0.91) and 0.67 (95% CI = 0.58-0.75), respectively.Conclusions: The results of meta-analysis indicate that DL algorithms improve the diagnosis of oral lesions. Future research should develop validated algorithms for automated diagnosis.Trial registration: Open Science Framework (https://osf.io/4n8sm).","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":"1054-1064"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0