Oral diseasesPub Date : 2025-09-07DOI: 10.1111/odi.70076
Piaopiao Chen, Mao Li, Qiong Zhang, Minxia Qiu, Xuefen Yu
{"title":"Effects of an Oral Health Management Program During Pregnancy: A Randomized Controlled Trial.","authors":"Piaopiao Chen, Mao Li, Qiong Zhang, Minxia Qiu, Xuefen Yu","doi":"10.1111/odi.70076","DOIUrl":"https://doi.org/10.1111/odi.70076","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of a Health Belief Model-based oral health management program on self-efficacy, oral health behaviors, and three periodontal clinical indicators among pregnant women.</p><p><strong>Study design: </strong>A randomized controlled trial was conducted with 65 participants randomly allocated to the intervention (n = 39) and control (n = 26) groups. The intervention included one face-to-face education, three video calls, two online lectures, and regular follow-up supervision in 1 month, while the control group received one face-to-face education. Self-efficacy for oral self-care, three periodontal clinical indicators, and oral health behaviors were measured at baseline (T<sub>0</sub>), post-intervention (T<sub>1</sub>), and 2-month follow-up (T<sub>2</sub>).</p><p><strong>Results: </strong>The total and three domains' scores on the Self-efficacy Scale for Self-care in the intervention group increased appreciably (p < 0.001). Oral health behaviors among the intervention group exhibited more remarkable improvement than the control group did at the two post-baseline times (all p < 0.05). The intervention group showed significantly higher scores in gingival index (p = 0.021) and plaque index (p = 0.001) than the control group at T<sub>1</sub>, while only plaque index scores were significantly different between the two groups at T<sub>2</sub> (p < 0.001).</p><p><strong>Conclusion: </strong>The findings demonstrated an effective educational strategy to promote self-efficacy, oral health behaviors, and oral health status in pregnant women.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-09-07DOI: 10.1111/odi.70093
Jinyan Guo, Mengting Zhang
{"title":"Comment on \"Tooth Anomalies in Patients With Nonsyndromic Orofacial Cleft: A Systematic Review and Meta-Analysis\".","authors":"Jinyan Guo, Mengting Zhang","doi":"10.1111/odi.70093","DOIUrl":"https://doi.org/10.1111/odi.70093","url":null,"abstract":"","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-09-07DOI: 10.1111/odi.70089
Júlia Silva Gomes de Araújo, Wellington Luiz de Oliveira da Rosa, Luiz Augusto Duarte Meirelles, Mateus Gaya Dos Santos, Noéli Boscato
{"title":"Effectiveness of Platelet-Rich Fibrin for Temporomandibular Disorders Management: A Systematic and Meta-Analysis.","authors":"Júlia Silva Gomes de Araújo, Wellington Luiz de Oliveira da Rosa, Luiz Augusto Duarte Meirelles, Mateus Gaya Dos Santos, Noéli Boscato","doi":"10.1111/odi.70089","DOIUrl":"https://doi.org/10.1111/odi.70089","url":null,"abstract":"<p><strong>Objective: </strong>This study systematically reviewed the effect of intra-articular injection (IAI) of platelet-rich fibrin (i-PRF), alone or combined with arthrocentesis or arthroscopy, in managing painful articular temporomandibular disorders (TMD) and improving maximum mouth opening (MMO).</p><p><strong>Materials and methods: </strong>A systematic literature search was conducted in five databases, identifying randomized and nonrandomized clinical trials focusing on minimally invasive TMJ interventions using i-PRF. Meta-analyses were performed with a random-effects model for studies reporting similar outcomes, visual analog scale (VAS) scores for pain, and MMO values.</p><p><strong>Results: </strong>Out of 332 studies identified, 13 met the inclusion criteria for meta-analysis. Within-group comparisons revealed significant pain reduction at 3-6 and 8-12 months for i-PRF alone or combined with arthrocentesis or arthroscopy. MMO values significantly increased using i-PRF alone at 8-12 months, combined with arthrocentesis or arthroscopy at 3-6 and 8-12 months, with no significant increase using i-PRF alone at 3-6 months. Between-group analyses demonstrated that i-PRF combined with arthrocentesis significantly reduced VAS scores and increased MMO values compared to arthrocentesis alone at 3-6 and 8-12 months.</p><p><strong>Conclusion: </strong>Using i-PRF alone or combined with arthrocentesis or arthroscopy is effective in pain reduction and MMO increase.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-09-03DOI: 10.1111/odi.70072
Muhammad Anas, Javed Iqbal, Brijesh Sathian
{"title":"Comment on \"A Case Control Study to Assess Frequency, Risk Factors, and Genetic Diversity of Entamoeba gingivalis\".","authors":"Muhammad Anas, Javed Iqbal, Brijesh Sathian","doi":"10.1111/odi.70072","DOIUrl":"10.1111/odi.70072","url":null,"abstract":"","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-09-02DOI: 10.1111/odi.70087
Yuxuan Zhang, Ran Liang, Pengyu Lai
{"title":"Comment on \"Diagnostic Performance of ChatGPT-4o and DeepSeek-3 Differential Diagnosis of Complex Oral Lesions: A Multimodal Imaging and Case Difficulty Analysis\".","authors":"Yuxuan Zhang, Ran Liang, Pengyu Lai","doi":"10.1111/odi.70087","DOIUrl":"https://doi.org/10.1111/odi.70087","url":null,"abstract":"","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Histochemical Assessment of Cementum and Alveolar Bone in SDT fa/fa Rat Mimicking Type II Diabetes.","authors":"Tomoka Hasegawa, Mako Sakakibara, Xuanyu Liu, Mai Haraguchi-Kitakamae, Weisong Li, Haoyu Wang, Yan Shi, Jiaxin Cui, Hiromi Hongo, Tomomaya Yamamoto, Miki Abe-Takagi, Haruhi Maruoka, Hirofumi Miyaji, Minqi Li, Norio Amizuka","doi":"10.1111/odi.70079","DOIUrl":"https://doi.org/10.1111/odi.70079","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the histopathology of diabetic periodontal tissues, we examined periodontal disease in Torii-Lepr<sup>fa</sup> (SDT fa/fa) rats, mimicking type 2 diabetes.</p><p><strong>Methods: </strong>Forty 30-week-old male SDT fa/fa rats and age-matched Sprague-Dawley (SD) rats were fixed, and the mandibular first molars and their periodontal tissues were histochemically examined.</p><p><strong>Results: </strong>SDT fa/fa rats exhibited epithelial downgrowth in the previous region of interradicular/interalveolar septa and periodontal spaces. Many osteoclasts and osteoblasts were present on the alveolar bone, indicating high bone turnover. Masses of bacteria were predominantly observed in the necrotic dental pulps and the cementum, where most cementocytic lacunae were empty. The cementum of the SDT fa/fa rats showed a distinct immunolocalization of osteocalcin, osteopontin, and dentin matrix protein-1 compared with the SD rats, but did not show advanced glycation end products, which were instead detected in some blood vessels and interstitial fibrous tissues associated with the down-growing epithelium.</p><p><strong>Conclusions: </strong>SDT fa/fa rats exhibited necrosis of dental pulp and severe periodontitis featuring markedly diminished alveolar bone because of stimulated bone resorption and formation. In addition, dead cementum may serve as bacterial nests, leading to changes in the localization of cementum matrix proteins.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-08-31DOI: 10.1111/odi.70084
Vandana Gupta, Anika Dawar, Sumit Kumar Das, Vikender Singh Yadav, Vanshita Nalwa, Razia Haidrus, Bharathi M Purohit, Lata Goyal
{"title":"Cardiovascular Biomarkers in Periodontitis: A Systematic Review and Meta-Analysis.","authors":"Vandana Gupta, Anika Dawar, Sumit Kumar Das, Vikender Singh Yadav, Vanshita Nalwa, Razia Haidrus, Bharathi M Purohit, Lata Goyal","doi":"10.1111/odi.70084","DOIUrl":"https://doi.org/10.1111/odi.70084","url":null,"abstract":"<p><strong>Aim: </strong>This review aimed to synthesize evidence on cardiovascular biomarkers associated with periodontitis, identified in biofluids such as blood, saliva, and gingival crevicular fluid (GCF).</p><p><strong>Methods: </strong>A comprehensive search of five databases was conducted to identify studies comparing cardiovascular biomarker levels in periodontitis and healthy individuals, up to 31 December 2024. Meta-analysis included biomarkers from ≥ 2 studies per biofluid, with sensitivity analysis performed and evidence certainty assessed using the GRADE tool.</p><p><strong>Results: </strong>Thirty-six studies were included in the systematic review, with 31 eligible for meta-analysis. Overall, 39 biomarkers were identified: 33 in blood, 14 in saliva, and 6 in GCF. A meta-analysis was conducted for 12 blood biomarkers, of which high-density lipoprotein (HDL) was significantly reduced, low-density lipoprotein (LDL) was higher in periodontitis (though LDL lost significance on sensitivity analysis), and the oxidative stress index (OSI) was significantly associated with periodontitis. No significant differences were observed for C-reactive protein (CRP), interleukin-1beta (IL-1ß), interleukin (IL)-6, N-terminal pro-B-type natriuretic peptide (NT-proBNP), monocyte chemoattractant protein-1 (MCP-1), and asymmetric dimethylarginine (ADMA). CRP was the only biomarker pooled for saliva and GCF, with no significant findings.</p><p><strong>Conclusion: </strong>Reduced blood HDL and elevated OSI represent potential cardiovascular biomarkers for periodontitis, although the certainty of evidence remains low.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral diseasesPub Date : 2025-08-31DOI: 10.1111/odi.70078
Paula Benito López, Daniela Adamo, Vito Carlo Alberto Caponio, José González-Serrano, Alan Roger Dos Santos Silva, Miguel de Pedro Herráez, Rui Albuquerque, María Pía López Jornet, Vlaho Brailo, Arwa Farag, Márcio Diniz Freitas, Noburo Noma, Richeal Ni Riordain, Gonzalo Hernández, Rosa María López-Pintor
{"title":"Can Large Artificial Intelligence-Based Linguistic Models Help to Obtain Information About Burning Mouth Syndrome?","authors":"Paula Benito López, Daniela Adamo, Vito Carlo Alberto Caponio, José González-Serrano, Alan Roger Dos Santos Silva, Miguel de Pedro Herráez, Rui Albuquerque, María Pía López Jornet, Vlaho Brailo, Arwa Farag, Márcio Diniz Freitas, Noburo Noma, Richeal Ni Riordain, Gonzalo Hernández, Rosa María López-Pintor","doi":"10.1111/odi.70078","DOIUrl":"https://doi.org/10.1111/odi.70078","url":null,"abstract":"<p><strong>Objective: </strong>Burning Mouth Syndrome (BMS) is an idiopathic chronic orofacial pain disorder with diagnostic and therapeutic challenges. Inexperienced clinicians may desperately resort to online information. The objective of this study was to evaluate the usefulness, quality, and readability of responses generated by three artificial intelligence large language models (AI-LLMs)-ChatGPT-4, Gemini, and Microsoft Copilot-to frequent questions about BMS.</p><p><strong>Materials and methods: </strong>Nine clinically relevant open-ended questions were identified through search-trend analysis and expert review. Standardized prompts were submitted, and responses were independently rated by 12 international experts using a 4-point usefulness scale. Quality was evaluated using the QAMAI tool. Readability was measured using Flesch-Kincaid Grade Level and Reading Ease scores. Statistical analyses included Kruskal-Wallis and Bonferroni correction.</p><p><strong>Results: </strong>All AI-LLMs produced moderately useful responses, with no significant difference in global performance. Gemini achieved highest overall quality scores, particularly in relevance, completeness, and source provision. Copilot scored lower in usefulness and source provision. No significant differences were obtained among AI-LLMs. Average readability corresponded to 12th grade, with ChatGPT requiring the highest proficiency.</p><p><strong>Conclusions: </strong>AI-LLMs show potential for generating reliable information on BMS, though variability in quality, readability, and source citation remains concerning. Continuous optimization is essential to ensure their clinical integration.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}