Oral diseases最新文献_第3页

Ferroptosis induced by plasma-activated Ringer's lactate solution prevents oral cancer progression. 血浆活化林格氏乳酸溶液诱导的铁下垂可防止口腔癌进展。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2023-12-04 DOI: 10.1111/odi.14827

Kotaro Sato, Ming Yang, Kae Nakamura, Hiromasa Tanaka, Masaru Hori, Miki Nishio, Akira Suzuki, Hideharu Hibi, Shinya Toyokuni

{"title":"Ferroptosis induced by plasma-activated Ringer's lactate solution prevents oral cancer progression.","authors":"Kotaro Sato, Ming Yang, Kae Nakamura, Hiromasa Tanaka, Masaru Hori, Miki Nishio, Akira Suzuki, Hideharu Hibi, Shinya Toyokuni","doi":"10.1111/odi.14827","DOIUrl":"10.1111/odi.14827","url":null,"abstract":"Objective: This study aimed to investigate the effect of plasma-activated Ringer's lactate solution (PAL) on oral squamous cell carcinoma (OSCC) cells and carcinogenic processes with a particular focus on iron and collagenous matrix formation.Materials and methods: We used three OSCC cell lines, one keratinocyte cell line, and two fibroblast lines, and cell viability assays, immunoblotting, flow cytometry, and transmission electron microscopy were performed to evaluate the effect and type of cell death. The effect of PAL treatment on lysyl oxidase (LOX) expression was investigated in vitro and in vivo. Tamoxifen-inducible Mob1a/b double-knockout mice were used for the in vivo experiment.Results: PAL killed OSCC cells more effectively than the control nontumorous cells and suppressed cell migration and invasion. Ferroptosis occurred and the protein level of LOX was downregulated in cancer cells in vitro and in vivo. Additionally, PAL improved the survival rate of mice and suppressed collagenous matrix formation.Conclusions: We demonstrated that PAL specifically kills OSCC cells and that ferroptosis occurs in vitro and in vivo. Furthermore, PAL can prevent carcinogenesis and improve the survival rate of oral cancer, especially tongue cancer, by changing collagenous matrix formation via LOX suppression.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mucoadhesive delivery systems for oral candidiasis treatment: A systematic review and meta-analysis. 用于治疗口腔念珠菌病的黏胶输送系统：系统综述和荟萃分析。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-03-24 DOI: 10.1111/odi.14928

Carolina Yoshi Campos Sugio, Amanda Aparecida Maia Neves Garcia, Klaryssa Akemi de Araujo Kitamoto, Joel Ferreira Santiago Júnior, Simone Soares, Vinicius Carvalho Porto, Vanessa Migliorini Urban, Priscileila Colerato Ferrari, Maria Helena Fernandes, Karin Hermana Neppelenbroek

{"title":"Mucoadhesive delivery systems for oral candidiasis treatment: A systematic review and meta-analysis.","authors":"Carolina Yoshi Campos Sugio, Amanda Aparecida Maia Neves Garcia, Klaryssa Akemi de Araujo Kitamoto, Joel Ferreira Santiago Júnior, Simone Soares, Vinicius Carvalho Porto, Vanessa Migliorini Urban, Priscileila Colerato Ferrari, Maria Helena Fernandes, Karin Hermana Neppelenbroek","doi":"10.1111/odi.14928","DOIUrl":"10.1111/odi.14928","url":null,"abstract":"Objectives: This systematic review and meta-analysis aimed to evaluate the clinical and mycological effectiveness of mucoadhesives as vehicles for drugs or natural products in the treatment of oral candidiasis.Materials and methods: The search for articles was carried out in the Medline/PubMed, SCOPUS, EMBASE, Web of Science, Cochrane Library, and SciELO databases before August 2023. We selected the studies, extracted the data, evaluated the study quality, graded the evidence, performed the risk of bias, and carried out meta-analysis.Results: A total of 389 potentially relevant articles were identified, and 11 studies (1869 participants) met the inclusion criteria of the systematic review. The overall risk of bias was considered low. The most common presentation of mucoadhesives was tablets, with miconazole being the most frequently drug used in the delivery system. Mucoadhesives demonstrated comparable efficacy with topical or systemic antifungal agents, with no significant differences between treatments in terms of clinical (RR = 0.907; 95CI = 0.3-1.297; p = 0.591; I2 = 64.648) or mycological (RR = 0.95; 95CI = 0.667-1.360; p = 0.789; I2 = 73.271) efficacy.Conclusions: Mucoadhesives may be a suitable alternative to conventional treatments, with the advantage of reducing the frequency of application by up to 5 times and the daily dosage by up to 20 times.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stabilized oral lichen planus does not compromise dental implants survival: A systematic review and meta-analysis. 稳定的口腔扁平苔藓不会影响牙科植入物的存活率：系统回顾和荟萃分析。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-05-12 DOI: 10.1111/odi.14964

Jing Wen Li, Wai Ying Kot, Colman Patrick McGrath, Bik Wan Amy Chan, Li Wu Zheng

{"title":"Stabilized oral lichen planus does not compromise dental implants survival: A systematic review and meta-analysis.","authors":"Jing Wen Li, Wai Ying Kot, Colman Patrick McGrath, Bik Wan Amy Chan, Li Wu Zheng","doi":"10.1111/odi.14964","DOIUrl":"10.1111/odi.14964","url":null,"abstract":"Background: This study aimed to evaluate the incidence of implant failure in patients with oral lichen planus (OLP) and investigate the potential association between OLP and peri-implant diseases.Materials and methods: Embase, Web of Science, PubMed, and Scopus databases were searched for studies with no time restrictions. Meta-analysis was performed calculating pooled proportion of peri-implantitis (PI), peri-implant mucositis (PIM), and bleeding on probing (BOP) prevalence using fixed-effects model. Odds ratio and corresponding 95% CI were calculated to assess the potential risk of PI, PIM, and BOP in dental implant patients with OLP compared to healthy controls.Results: Implant failure rate was 4.38% at the patient level and 4.37% at the implant level. Six patients (3.92%) from five studies were diagnosed with oral cancer after receiving implant. The prevalence of PI, PIM, and BOP at the implant level were 14.00%, 20.00%, and 40.00%, respectively. There was no significant difference in the occurrence of PI and PIM between OLP patients and healthy controls.Conclusions: Stabilized OLP is not considered a significant risk factor for peri-implant diseases. It is advised against placing implants or prostheses during the acute phase of the disease. Histopathological investigation to differentiate OLP from oral lichenoid dysplasia is crucial.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of adjunctive modalities during tooth extraction for the prevention of osteoradionecrosis: A systematic review and meta-analysis. 拔牙期间预防骨软化症的辅助方法的功效：系统回顾与荟萃分析。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-02-23 DOI: 10.1111/odi.14902

Bernadette Quah, Chee Weng Yong, Clement Wei Ming Lai, Intekhab Islam

{"title":"Efficacy of adjunctive modalities during tooth extraction for the prevention of osteoradionecrosis: A systematic review and meta-analysis.","authors":"Bernadette Quah, Chee Weng Yong, Clement Wei Ming Lai, Intekhab Islam","doi":"10.1111/odi.14902","DOIUrl":"10.1111/odi.14902","url":null,"abstract":"Background: Jaw osteoradionecrosis (ORN) is a complication in patients with previous head and neck radiotherapy. Its incidence increases with dental extractions. Hence, this review aimed to evaluate the efficacy of adjunctive treatment modalities undertaken at the time of extraction in previous head and neck radiotherapy patients in preventing ORN.Methods: A systematic review was conducted, where studies with data on ORN incidence after extraction with or without adjunctive interventions were included. Meta-analyses were conducted to estimate the pooled prevalence of ORN per intervention and the pooled odds ratio for incidence of ORN between interventions.Results: In total, 1520 patients in 29 studies were included. Interventions identified were hyperbaric oxygen (HBO), pentoxifylline-tocopherol (PENTO), antibiotics (ABX), platelet-rich fibrin and photobiomodulation. The pooled prevalence of ORN for HBO (4.6%), PENTO (3.4%) and ABX (3.8%) was significantly lower than the Control (17.6%). For studies with direct comparisons between groups, HBO had lower but not significant odds of developing ORN than the Control (OR 0.27) and ABX (OR 0.57).Conclusions: HBO, PENTO and ABX may reduce the incidence of ORN compared to no intervention. Given that all three have similar incidences of ORN, ABX may be the most cost-effective and accessible adjunctive modality.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139940431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Authors' reply: Association between oral lichen planus and Hashimoto thyroiditis: A systematic review. 回复：重新评估口腔扁平苔藓与桥本氏甲状腺炎之间的关联。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2023-12-17 DOI: 10.1111/odi.14848

Lapo Serni, Luigi Barbato, Michele Nieri, Mattia Mallardi, Désirée Noce, Francesco Cairo

引用次数: 0

Acromegaly: Overview and associated temporomandibular joint disorders. 肢端肥大症：概述及相关的颞下颌关节疾病。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-01-15 DOI: 10.1111/odi.14861

Malak Al-Hadlaq, Herve Sroussi

{"title":"Acromegaly: Overview and associated temporomandibular joint disorders.","authors":"Malak Al-Hadlaq, Herve Sroussi","doi":"10.1111/odi.14861","DOIUrl":"10.1111/odi.14861","url":null,"abstract":"Objective: To provide a review on acromegaly and its orofacial manifestations, with a focus on associated arthropathies and temporomandibular joint disorders (TMD).Methods: A review of current literature was performed through an electronic search of three databases: PubMed, ScienceDirect, and Google Scholar. The literature review was focused on the following topics of interest: etiology, diagnosis, and management of acromegaly, orofacial manifestations of acromegaly, acromegalic arthropathies, and acromegaly-associated TMD.Results: Acromegaly is a chronic multisystem condition in which excessive production of growth hormone in adults, most commonly caused by benign pituitary adenomas, leads to somatic overgrowth. Orofacial changes are considered hallmarks of the disease. It is important for dentists to recognize signs and symptoms of acromegaly, as this may help to achieve early diagnosis and improve overall disease prognosis. Acromegalic arthropathies typically involve large joints, however, the temporomandibular joints (TMJ) can be affected. TMD associated with acromegaly is under-recognized and poorly characterized in current literature.Conclusion: In the appropriate clinical context, acromegaly should be considered as part of the differential diagnosis for patients presenting with TMD. Further studies are needed to better characterize the nature of TMD associated with acromegaly and to define the role of TMJ involvement in early diagnosis.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139472835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "Tongue metastasis of malignant melanoma: A case report and a systemic review of the literature"Iiris Sääksjärvi, Sara Degerholm, Hanna Ahde, Tuula Salo, Matti Mauramo. (2023). Tongue metastasis of malignant melanoma: A case report and a systemic review of the literature. Oral Diseases, 30(3), 949-956. 更正："恶性黑色素瘤的舌转移：病例报告和文献系统回顾 "Iiris Sääksjärvi、Sara Degerholm、Hanna Ahde、Tuula Salo、Matti Mauramo。(2023).恶性黑色素瘤的舌头转移：病例报告和文献系统回顾。口腔疾病》，30（3），949-956。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1111/odi.15039

引用次数: 0

Application of metabolomics in oral squamous cell carcinoma. 代谢组学在口腔鳞状细胞癌中的应用

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-02-20 DOI: 10.1111/odi.14895

Guanfa Luo, Shuai Wang, Wen Lu, Wei Ju, Jianhong Li, Xiao Tan, Huiting Zhao, Wei Han, Xihu Yang

{"title":"Application of metabolomics in oral squamous cell carcinoma.","authors":"Guanfa Luo, Shuai Wang, Wen Lu, Wei Ju, Jianhong Li, Xiao Tan, Huiting Zhao, Wei Han, Xihu Yang","doi":"10.1111/odi.14895","DOIUrl":"10.1111/odi.14895","url":null,"abstract":"Background: Oral squamous cell carcinoma (OSCC) is a prevalent malignancy affecting the head and neck region. The prognosis for OSCC patients remains unfavorable due to the absence of precise and efficient early diagnostic techniques. Metabolomics offers a promising approach for identifying distinct metabolites, thereby facilitating early detection and treatment of OSCC.Objective: This review aims to provide a comprehensive overview of recent advancements in metabolic marker identification for early OSCC diagnosis. Additionally, the clinical significance and potential applications of metabolic markers for the management of OSCC are discussed.Results: This review summarizes metabolic changes during the occurrence and development of oral squamous cell carcinoma and reviews prospects for the clinical application of characteristic, differential metabolites in saliva, serum, and OSCC tissue. In this review, the application of metabolomic technology in OSCC research was summarized, and future research directions were proposed.Conclusion: Metabolomics, detection technology that is the closest to phenotype, can efficiently identify differential metabolites. Combined with statistical data analyses and artificial intelligence technology, it can rapidly screen characteristic biomarkers for early diagnosis, treatment, and prognosis evaluations.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The emerging meanings of spirituality in oral medicine practice. 口腔医学实践中出现的灵性意义。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2023-12-04 DOI: 10.1111/odi.14831

Alan Roger Santos-Silva, Daniel Galera Bernabé

引用次数: 0

Eminent science support from Jews to the young Turkish republic; a particular focus on dentistry. 犹太人为年轻的土耳其共和国提供的杰出科学支持；特别关注牙科。

IF 2.9 3区医学

Oral diseases Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI: 10.1111/odi.15064

Nurcan Buduneli, Raffaela Nemecek, Mehmet Demirbaş, James Deschner

引用次数: 0