Nigerian Journal of Clinical Practice最新文献

{"title":"The Relationship between Choroidal Thickness and Liver Damage in Simple Autoimmune Hepatitis Patients.","authors":"","doi":"10.4103/njcp.njcp_904_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_904_24","url":null,"abstract":"","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"776"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Violence Tendency and Premenstrual Symptoms among University Students: A Cross-Sectional Study in Turkey.","authors":"L Kutlu, Y V Yıldırım","doi":"10.4103/njcp.njcp_780_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_780_24","url":null,"abstract":"<p><strong>Background: </strong>Literature discusses the relationship between young women's violent tendencies and biological, psychological, and social factors. Notably, hormonal fluctuations during the menstrual cycle are reflected in mood swings and aggression levels, which may increase the tendency of young women to resort to violence.</p><p><strong>Aim: </strong>This study aimed to evaluate the relationship between violent tendencies and premenstrual symptoms in university students.</p><p><strong>Methods: </strong>Data for this cross-sectional analytical study were collected from 1301 students via a Google survey between January and May 2020 using the Personal Information Form, Premenstrual Syndrome Scale (PMSS), and Violence Tendency Scale (VTS).</p><p><strong>Results: </strong>It was determined that 65.3% of students had PMS, and the students' VTS scores was high in 25.8% of them and low in 73.2 of them. There was significant correlation between the students' VTS scores in both subscales and total scores of PMSS (P < 0.05), PMSS' anxiety (β = 0.171), irritability (β = 0.348), and sleep changes (β = 0.182) subscale scores positively affected VTS scores (P < 0.05).</p><p><strong>Conclusion: </strong>Most of the students in the study were found to suffer from PMS, and PMS symptoms, particularly anxiety, irritability, and sleep disturbances, were associated with higher VTS scores. These results suggest that specific symptoms of PMS may play an important role in determining students' VTS scores, and this may have implications for understanding PMS broader effects on student wellbeing and performance. Health professionals can provide education and health services aimed at reducing premenstrual symptoms, preventing violent tendencies, and providing resources and foundations for future studies by conducting more studies.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"677-686"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assocıatıons Between Vıtamın D Receptor Gene Polymorphısms and Carpal Tunnel Syndrome.","authors":"B Yildiz, F E Algul, E Yesilada","doi":"10.4103/njcp.njcp_774_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_774_24","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D deficiency is associated with Carpal tunnel syndrome (CTS), and Vitamin D supplementation may improve symptoms and electrophysiological findings in CTS patients. The biological effects of vitamin D may be modified by various genetic factors, including single nucleotide polymorphisms in the vitamin D receptor (VDR) gene.</p><p><strong>Aim: </strong>With this study, we aimed to show whether Taq I and Fok I polymorphisms of the VDR gene cause an increase in the occurrence and severity of carpal tunnel syndrome.</p><p><strong>Methods: </strong>100 CTS patients and 100 healthy controls were included in this study. The severity of CTS was determined by electromyography and the patients were divided into 3 groups: mild, moderate and severe CTS. The Fok I and Taq I genotypes of the participants were determined from the peripheral blood samples taken from all participants. Genotypes and allele frequencies were compared between patient and control groups.</p><p><strong>Results: </strong>VDR Fok I genotype distribution and allele frequency showed a significant relationship with the risk of developing CTS and its severity. Taq I, on the other hand, was not associated with the risk of developing CTS or its severity.</p><p><strong>Conclusion: </strong>VDR Fok I polymorphism increases the risk of developing CTS and the risk of severe CTS in the Turkish population. Further studies on this subject are needed to further understand the relationship between CTS and VDR polymorphisms and explain its mechanism.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"716-720"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of Professional Competence and Competency Scale in Midwifery: A Methodological Study from Turkey.","authors":"M Balcik Colak, H Ozturk Can","doi":"10.4103/njcp.njcp_55_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_55_25","url":null,"abstract":"<p><strong>Background: </strong>The main scope of competence in midwifery is the skills and practices relevant to the profession. Competencies are used to set unique standards within disciplines and specializations, including educators, learners, and practitioners.</p><p><strong>Aim: </strong>This study was aimed at developing the Professional Competence and Competency Scale in Midwifery.</p><p><strong>Methods: </strong>This was a methodological and validation study. The scale consists of 26 items. The created items were administered to 362 midwives. According to the results of the exploratory and confirmatory factor analysis of the factor pattern for all the items, ideally, the scale has a two-dimensional distribution. Responses given to the items are rated on a five-point Likert-type scale.</p><p><strong>Results: </strong>According to the item-total test correlation, all the items were related to each other. The Cronbach's Alpha value was 0.953 for the overall Professional Competence and Competency Scale in Midwifery, 0.917 and 0.932 for its \"Professional Responsibilities and Communication Skills\" and \"Professional Knowledge, Skills and Practices\" sub-dimensions, respectively. In addition, the scale has construct validity.</p><p><strong>Conclusion: </strong>According to the findings of the validity and reliability study of The Professional Competence and Competency Scale in Midwifery, it is a valid, reliable tool, and it is discriminative in terms of measuring the desired quality.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"721-729"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Bone Density Between Central Incisors Using Fractal Analysis in Patients Undergoing Surgically Assisted Rapid Maxillary Expansion.","authors":"T Pergel, E F Akkoyun, E A Alagoz","doi":"10.4103/njcp.njcp_892_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_892_24","url":null,"abstract":"<p><strong>Background: </strong>Surgically assisted rapid palatal expansion (SARPE) is a widely used method for correcting maxillary transverse deficiency.</p><p><strong>Aim: </strong>This study aims to investigate the changes in bone trabeculae and healing on the midline osteotomy line of the central incisors on panoramic radiographs taken preoperatively and 6 months postoperatively in patients who underwent SARPE using the fractal analysis (FA) method.</p><p><strong>Methods: </strong>The study population consisted of 36 patients (5 male and 31 female) diagnosed with maxillary transverse deficiency and operated with SARPE. Fractal analyses observed the alterations on the trabecular structure in the vertical osteotomy line between central incisors on panoramic radiographs obtained preoperatively and 6 months postoperatively. The box-counting method was used to evaluate the changes in trabecular structure by FA. P values of less than 0.05 were considered significant.</p><p><strong>Results: </strong>The fractal dimension values of the vertical osteotomy lines returned to their preoperative levels by the sixth postoperative month. There were no statistically significant changes between preoperative and postoperative 6 months on the panoramic radiographs in the vertical osteotomy line (P = 0.057).</p><p><strong>Conclusion: </strong>Postoperative fractal analyses can reveal trabecular changes and bone healing in structures such as the vertical osteotomy line. Six months after the SARPE, central incisors can be moved orthodontically toward each other. The bone healing between central incisors was uneventful, and the bone trabeculae structure was approximately the same as during the preoperative period.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 5","pages":"595-601"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension in the Young: A Post-Hoc Analysis of Two Studies in Enugu State.","authors":"C C Okwara, B A Ezeala-Adikaibe, P O Njoku, N C Mbadiwe, T H Ikenwugwu, E A Ekwe, O B Anyim, F Ekochin, C M Abonyi, G E Anigbo","doi":"10.4103/njcp.njcp_693_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_693_24","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a common cardiovascular disease among the young Nigerians. Little is known about urban-rural differences in the pattern hypertension in the young Nigerians.</p><p><strong>Aim: </strong>The aim of this study was to describe the pattern of hypertension in young Nigerians in a rural and urban settings and to establish the differences between them if any.</p><p><strong>Methods: </strong>Data for the index study was retrieved from two previous studies. Blood pressures were measured according to the guidelines of the European Society of Hypertension.</p><p><strong>Results: </strong>Data from 605 participants were included in the study: urban 360 (59.7%) and rural 245 (40.5%). Males were 158 (21.6%) and females were 447 (73.9%). The mean age of the populations was (urban 30 ± 6 years and rural 29.2 ± 0.63 years P = 0.47). The overall prevalence of hypertension in this study was 35.9% (217/605), similar in urban (36.1%) and rural (35.9%) dwellers P = 0.88. Forty-two (6.9%) were previously diagnosed (urban 39 (30%) and rural 3 (3.4%), P < 0.01. About 66.7% were controlled (urban 25 (64.1%) and rural 3 (100%). Urban dwellers have significantly higher rates of raised diastolic blood pressure compared to rural dwellers, who had higher rates of systolic blood pressure. In both locations, although there was no sex difference in the prevalence of hypertension, hypertension significantly increased with age.</p><p><strong>Conclusion: </strong>There is a high rate of hypertension in rural and urban middle-aged Nigerians in Enugu southeast Nigeria. Continuous educational programs will be important in reducing both the morbidity and complications of hypertension in the future.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 5","pages":"574-581"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy Analysis of PKP and PMCP in Treatment of Osteoporotic Vertebral Compression Fracture.","authors":"L Zhou, J Gu, F Xu, P Li, S He, P Zhang","doi":"10.4103/njcp.njcp_22_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_22_24","url":null,"abstract":"<p><strong>Background: </strong>Osteoporotic vertebral compression fractures (OVCFs) represent the most common fragility fractures in the elderly population. These fractures frequently cause refractory back pain and progressive kyphosis, with subsequent high risks of vertebral refracture, ultimately leading to substantial disability, elevated mortality rates, and considerable socioeconomic burdens. Current therapeutic strategies prioritize minimally invasive approaches that are safe, technically feasible, and effective, with the primary goals of early functional recovery and quality of life restoration. Currently, the mainstream consensus favors minimally invasive surgical interventions.</p><p><strong>Aim: </strong>To compare the efficacy of percutaneous kyphoplasty (PKP) versus percutaneous 28 mesh-container-plasty (PMCP) for OVCF.</p><p><strong>Methods: </strong>The clinical data of 75 patients with thoracolumbar OVCF surgically treated in our hospital from March 2021 to March 2023 were reviewed and analyzed, of which 45 cases were treated with PKP, 30 cases were treated with PMCP, and the follow-up time was from 8 to 12 months. We compared the basic clinical data, surgical conditions, VAS (Visual Analog Scale), and ODI (Oswestry Disability Index) scores before and after surgery, the heights of the anterior and middle margins of the injured vertebrae, the Cobb angle of the injured vertebrae, and the leakage and distribution of bone cement between the two groups.</p><p><strong>Results: </strong>The VAS and ODI scores, the height, and the Cobb angle of the injured vertebrae of the two groups were improved compared with those of the preoperative period, and the difference was statistically significant (P < 0.05). The PMCP group had longer operation time, larger amount of bone cement injection, more reasonable distribution, lower leakage rate, and better recovery of the vertebral height and the Cobb angle, compared with the PKP group, and the difference was statistically significant (P < 0.05).</p><p><strong>Conclusion: </strong>Both PKP and PMCP can effectively improve the pain symptoms and dysfunction of patients with OVCF, and the operation time of PMCP group is longer than that of the PKP group, but it can better improve the height and kyphosis of injured vertebrae, and the distribution of bone cement is more reasonable and the leakage rate is lower.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 5","pages":"641-647"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Zinc, Selenium and Vitamin C Status in Maternal and Umbilical Cord Blood of Intrapartum Women in Enugu Metropolis, Enugu State, Nigeria.","authors":"C M Adilieje, C S Ejezie, H O Obianyido, C C Ugwu, O S Ezeadichie, F E Ejezie","doi":"10.4103/njcp.njcp_467_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_467_24","url":null,"abstract":"<p><strong>Background: </strong>Zinc, selenium, and vitamin C are vital antioxidants that mitigate oxidative stress. Pregnancy-induced metabolic changes may alter their levels, affecting maternal and fetal health.</p><p><strong>Aim: </strong>This study evaluated zinc, selenium, and vitamin C concentrations in maternal and umbilical cord blood of women in labor in Enugu Metropolis, Nigeria.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 48 mother-neonate pairs. Maternal and umbilical cord blood samples (5 mL each) were collected postpartum. Zinc and selenium were analyzed using atomic absorption spectrophotometry, while vitamin C was measured colorimetrically.</p><p><strong>Results: </strong>Mean maternal and cord serum zinc levels were 41.61 ± 2.45 µg/dL and 42.65 ± 4.7 µg/dL, respectively, indicating deficiency. Selenium averaged 168.10 ± 14.47 µg/L in maternal serum and 197.56 ± 16.74 µg/L in cord blood, with neonatal levels exceeding physiological limits. Vitamin C concentrations were 7.53 ± 0.26 mg/L (maternal) and 7.11 ± 0.50 mg/L (cord), both within normal ranges. Correlation analysis showed a weak maternal-cord zinc relationship (r = 0.11, P = 0.46), a significant positive correlation for selenium (r = 0.48, P = 0.00059), and a slight negative correlation for vitamin C (r = -0.022, P = 0.88).</p><p><strong>Conclusion: </strong>Zinc deficiency in maternal and cord blood highlights the need for routine monitoring and supplementation. Elevated neonatal selenium suggests potential toxicity risks, requiring further research. Adequate vitamin C levels indicate sufficient nutrition, supporting immune function and oxidative stress reduction. These findings emphasize the importance of maternal micronutrient balance for neonatal health.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 5","pages":"565-573"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Anxiety and its Associated Factors among Adult Patients Undergoing Elective Surgery in Tertiary Hospitals in Enugu, Southeast Nigeria.","authors":"C J Mbadugha, N J Omotola, J E Emega, O T Madu, A L Obiekwu","doi":"10.4103/njcp.njcp_404_22","DOIUrl":"https://doi.org/10.4103/njcp.njcp_404_22","url":null,"abstract":"<p><strong>Background: </strong>Anxiety before surgery is an influential element in the pre-operative care and postoperative outcome of patients. Identifying the level of pre-operative anxiety and possible factors will enable health professionals to provide appropriate psychological care aimed at preventing potential post-operative complications.</p><p><strong>Aim: </strong>This study aimed to assess the level of pre-operative anxiety and associated factors among adult patients undergoing elective surgery in two tertiary hospitals that provide surgical services in Southeast Nigeria.</p><p><strong>Methods: </strong>A descriptive cross-sectional study design was adopted. Ninety-eight adults booked for surgery in selected hospitals were assessed using a standardized (State and trait anxiety inventory) instrument to obtain information on their anxiety level and contributing factors.</p><p><strong>Results: </strong>The prevalence of anxiety in the study was 55%. Financial loss due to hospitalization (52%), fear of postoperative pain (50%), and fear of complications (51%) were the major factors that precipitated anxiety among respondents. Patients with acute cases (36.1%) and no previous experience with general anesthesia (79%) were associated with higher levels of anxiety than their counterparts. Provision of preoperative counseling was insignificant in influencing the level of anxiety (P > 0.05). The main strategies used by patients were praying and meditating.</p><p><strong>Conclusion: </strong>Patients undergoing elective surgery experience pre-operative anxiety. Inadequate information during the preoperative period was implicated as a factor that contributed to high anxiety levels among those who received preoperative counseling. Therefore, improving preoperative counseling sessions and ensuring the availability of social support is likely to reduce the prevalence of preoperative anxiety and facilitate postoperative recovery.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 5","pages":"633-640"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous Tranexamic Acid Reduces Blood Loss and Transfusion Requirements in Total Knee Replacement Surgery: A Double-Blind Controlled Study in a Regional Hospital, Southwest, Nigeria.","authors":"M E Ugbeye, K A Alatishe, S O Olanrewaju, W O Lawal, I J Akpan, U C Nwose","doi":"10.4103/njcp.njcp_57_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_57_24","url":null,"abstract":"<p><strong>Background: </strong>Tranexamic acid (TXA) is one of the agents used to reduce perioperative bleeding during total knee replacement. However, there is no consensus or guidelines for its use in our environment.</p><p><strong>Objective: </strong>We assessed the effectiveness of intravenous TXA compared to placebo for reducing blood loss and blood transfusion requirements in total knee replacement (TKR).</p><p><strong>Methods: </strong>This prospective, randomized, double-blind study was conducted at our regional hospital between January 2016 and June 2017. Patients with severe osteoarthritis scheduled to undergo TKR were randomly allocated to the placebo and TXA groups. Intraoperative blood loss (IBL), postoperative blood loss (PBL), total blood loss (TBL), hemoglobin (Hb) drop, and transfusion rates were compared between the two groups.</p><p><strong>Results: </strong>A total number of 72 patients (98 knees) were randomized to two groups. Thirty-six patients (52 knees) in the placebo group and the remaining 36 patients (46 knees) were randomized in TXA group. The baseline demographic data were similar in both groups [Table 1]. The mean IBL, PBL, and TBL in TXA group (187.7 ± 46.2 mL, 334.4 ± 85.9 mL and 574.3 ± 102.1 mL) were significantly lower than those in the placebo group (344.3 ± 89.0 mL, P < 0.001; 628.0 ± 197.4 mL, P < 0.001; and 946.5 ± 152.3 mL, P < 0.001) [Table 2]. The mean Hb drop was lower in TXA group compared to placebo (P < 0.001). The transfusion rate in TXA group was significantly lower when compared to placebo (P = 0.03).</p><p><strong>Conclusion: </strong>Intravenous TXA is effective in reducing perioperative bleeding, hemoglobin loss, and blood transfusion requirements in TKR.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 5","pages":"590-594"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}