Nigerian Journal of Clinical Practice最新文献

{"title":"Effect of Acupoint Application and Massage on the Comfort Degree and Stress State of Patients Undergoing Noninvasive Mechanical Ventilation due to Acute Chronic Obstructive Pulmonary Exacerbation in Dali, China.","authors":"M W Liu, Y K Shi, B C Zhang, Z Q Ma, Q K He, X Y Duan","doi":"10.4103/njcp.njcp_167_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_167_24","url":null,"abstract":"<p><strong>Background: </strong>Noninvasive mechanical ventilation (NIPPV) can improve oxygenation and ventilation in patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD), but some patients may struggle to acclimate to it, ultimately leading to treatment failure.</p><p><strong>Aim: </strong>To determine the impact of acupoint application and massage on the comfort degree and stress state of patients with AECOPD undergoing NIPPV.</p><p><strong>Methods: </strong>A total of160 AECOPD patients were endeavored to study with a retrospective study. The 160 participants were randomly divided into NIPPV group and acupoint application and massage accompany with NIPPV groups with 80 cases each. Changes in the comfort degree, anxiety index, stress indicators, satisfaction degree, hospitalization time, stop using NIPPV time, blood gas indicators before and after NIPPV treatment, and the treatment effect were detected for the two groups.</p><p><strong>Results: </strong>In contrast to NIPPV as a solitary treatment, the integration of acupoint therapy and massage with NIPPV markedly enhanced patient comfort and eased their stress levels; it substantially diminished the anxiety index, alleviated frontal sinus pain and abdominal bloating, reduced the duration of offline periods and hospital stays, and significantly betters the eating and sleeping quality of patients (P < 0.05).</p><p><strong>Conclusion: </strong>Acupoint application and massage can improve the comfort degree, stress state, and anxiety; shorten the NIPPV time and hospital stay; reduce the intubation rate; and improve the treatment effect of patients with AECOPD undergoing NIPPV.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"838-847"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Glaucoma Drainage Device Surgeries in Nigeria.","authors":"A S Kalambe, A C Ezenwa, A C Okudo, C G Onochie-Olubobokun, B J Adekoya, L W Herndon, M G Odeyemi, A O Ogunro, B U Erikitola, O U Smith","doi":"10.4103/njcp.njcp_328_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_328_25","url":null,"abstract":"<p><strong>Background: </strong>Glaucoma is the leading cause of functional low vision and irreversible blindness in Nigeria and constitutes a significant public health burden. Glaucoma Drainage Devices(GDD) an increasingly popular option for glaucoma treatment and are relatively new in Nigeria.</p><p><strong>Aim: </strong>To evaluate the clinical outcomes, number of anti-glaucoma medications and complications in patients who had glaucoma drainage devices implants from a certified skills transfer training program.</p><p><strong>Methods: </strong>This was a one year retrospective case series review of patients with GDD implants during a skills transfer certification training program in Nigeria in 2023.</p><p><strong>Results: </strong>Twenty three participants made up of 14 males and 9 females with a mean age of 57.6 SD 14.7 underwent a GDD surgical procedure. The mean pre-operative intraocular pressure of the participants was 23.6±8.7, which dropped to 14 mmHg ± 4.9 mmHg at one year (P = 0.007). The average number of medications of the participants before the GDD implants was 3.3±0.9, and this reduced to 1.4 ± 1.3 medication at one year (P = 0.003). One patient had scleral melting and another had accelerated cataract with tube-cornea touch.</p><p><strong>Conclusion: </strong>The satisfactory clinical outcome from this procedure justifies the benefits of GDD surgical skill transfer program. We recommend the use of GDD implants as a treatment option for glaucoma in Nigeria.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"858-863"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Children's Hospital of Philadelphia Score Algorithm for Screening Retinopathy of Prematurity in Premature Infants in Saudi Arabia.","authors":"L H Raffa, N Bawajeeh, R A Alothman, M Siddiqui, H S Almarzouki","doi":"10.4103/njcp.njcp_138_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_138_25","url":null,"abstract":"<p><strong>Background: </strong>Retinopathy of prematurity (ROP) causes blindness among children, particularly preterm infants. While several screening models exist, their performance in developing countries is not well established. This study assessed the accuracy of Children's Hospital of Philadelphia-Retinopathy of Prematurity (CHOP-ROP) in Saudi Arabia and compared it with other models.</p><p><strong>Objective: </strong>To assess the diagnostic performance of the CHOP-ROP model in Saudi preterm infants and compare it with other ROP screening tools.</p><p><strong>Methods: </strong>This retrospective study involving 524 preterm infants was conducted in two tertiary hospitals in Jeddah. ROP risk was assessed using the CHOP-ROP and compared with four ROP risk models. Predictive values, specificity, sensitivity, and receiver operating characteristic curves were analyzed. Logistic regression identified type 1 ROP predictors.</p><p><strong>Results: </strong>Any-stage ROP was detected in 22.3% of infants; 9.1% required treatment. CHOP-ROP had the highest specificity (62.5%), accuracy (64.2%), and area under the curve (AUC) (0.71), indicating better ability to distinguish infants needing treatment, though its sensitivity was lower (81.4%) than other models. Lower birth weight, longer neonatal intensive care unit stay, and early blood transfusion were significant type 1 ROP predictors (all, P < 0.05).</p><p><strong>Conclusion: </strong>Although CHOP-ROP demonstrated strong specificity and accuracy, its lower sensitivity raises concerns about missed cases requiring treatment. Compared to more sensitive local tools, its performance was suboptimal. Region-specific model validation and threshold adjustments are needed to enhance its predictive value while minimizing false negatives.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"783-789"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Prognostic Factors in Patients with Cranial Gunshot Wounds.","authors":"K Oktay, M Mammadov, A Alnageeb, H E Alcan, U Pektaş, K M Ozsoy, N E Cetinalp, T Erman","doi":"10.4103/njcp.njcp_863_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_863_24","url":null,"abstract":"<p><strong>Background: </strong>In recent years, cranial gunshot wounds become a growing concern for neurosurgeons due to factors such as the increase in civil wars, terrorist activities, and the global rise in civilian gun ownership.</p><p><strong>Aim: </strong>To evaluate the prognostic factors in patients with cranial gunshot wounds.</p><p><strong>Methods: </strong>The current study included 124 patients who received either conservative or surgical treatment for cranial gunshot wounds between October 2014 and April 2024. The data including age, gender, clinical parameters (Glasgow coma scale (GCS), pupillary examination, admission time, high or low-velocity gunshot injuries), radiological parameters (pattern of injury, presence of midline cross of the projectiles, affected brain lobes, presence of foreign body in the cranium, accompanying pathologies), and treatment parameters (treatment modalities, complications, and Glasgow outcome scale) were retrospectively collected.</p><p><strong>Results: </strong>The mean age of the patients was 26.29 ± 10.76 years (2-76 years). Sixteen patients (12.9%) were female, and 108 patients (87.1%) were male. Ninety-four patients (75.8%) had gunshot wounds related to Syrian civil war, 18 patients (14.5%) had accidental injuries, and 12 patients (9.7%) had suicide injuries. Higher initial GCS scores, isochoric pupils, low-velocity injuries, tangential injuries, the absence of midline cross of the projectiles, unihemispheric unilobar injuries, the absence of accompanying hematomas, and the lack of complications were statistically significantly correlated with favorable outcomes (P = 0.001). The overall mortality rate in the study cohort was 41.1% (51 patients). Fifty-five patients (44.4%) had favorable outcome, while 69 patients (55.6%) had poor outcome. Fifty-six complications were determined in 38 patients. Neurodeficits (32.1%), cerebrospinal fluid fistula and wound dehishence (21.4%), and systemic infections (21.4%) were primary complications.</p><p><strong>Conclusion: </strong>In the present study, low initial GCS scores, fixed pupils, high-velocity injuries, perforating injuries, the presence of the midline cross of the projectiles, bihemispheric injuries, the presence of IVH, the presence of the complications, and the lack of surgical treatment showed statistically significant influence on mortality. Among these predictors, lower initial GCS scores, fixed pupils, midline cross of the projectiles, and complications were found to be the primary risk factors for mortality. Additionally, surgical treatment was found to reduce mortality rates.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"816-823"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Study on the Relationship between the HEART Score and the Severity of CAD using the SYNTAX Score in Patients with NSTEMI Admitted to the Emergency Department: A Study from Turkey.","authors":"M S Pepele, I Aktas, O Demiroz, S Derya, E Yildirim, M N Bilen, B Demir","doi":"10.4103/njcp.njcp_417_24","DOIUrl":"10.4103/njcp.njcp_417_24","url":null,"abstract":"<p><strong>Background: </strong>The HEART score is a risk stratification tool for acute chest pain, evaluating history, ECG, age, risk factors, and troponin. The SYNTAX (synergy between percutaneous coronary intervention with TAXUS and cardiac surgery) score assesses the extent and complexity of coronary artery disease (CAD) and is widely used in patients undergoing coronary interventions.</p><p><strong>Aim: </strong>To determine the relationship between the HEART and SYNTAX scores in patients with non-ST elevation myocardial infarction (NSTEMI).</p><p><strong>Method: </strong>A total of 222 NSTEMI patients who underwent coronary angiography were included. The HEART score was calculated at admission, and all patients underwent angiography within 12 hours. SYNTAX was used to evaluate CAD severity. Patients were divided into two groups based on SYNTAX scores. Comparisons were made according to demographic data, laboratory findings, and risk factors. Variables associated with high SYNTAX scores were identified. A P value of < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The mean age was 63.67 ± 11.89 years, and 74.77% of the patients were male. Patients with high SYNTAX scores had significantly higher HEART scores and more frequent diabetes and hypertension. High HEART score (OR: 3.09; 95% confidence intervals [CI]: 2.06-4.63; P < 0.001) and diabetes mellitus (OR: 4.57; 95% CI: 1.44-14.47; P = 0.010) were independently associated with high SYNTAX scores. A HEART score >7.5 predicted high SYNTAX scores with 82.1% sensitivity and 84.3% specificity (area under curve [AUC]: 0.892; P < 0.001). A strong positive correlation was found between HEART and SYNTAX scores (P < 0.001, R² =0.672).</p><p><strong>Conclusion: </strong>The HEART score was significantly associated with the severity and complexity of CAD in patients with NSTEMI.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"758-763"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Factors Affecting the Nutritional Behavior and Nutritional Knowledge Levels of Breastfeeding Women in the Postpartum Period.","authors":"E Sarı, A Eker, A Saltekin","doi":"10.4103/njcp.njcp_834_24","DOIUrl":"10.4103/njcp.njcp_834_24","url":null,"abstract":"<p><strong>Background: </strong>Postpartum women's nutrition is shaped by social, psychological, and cultural factors, affecting maternal and infant health.</p><p><strong>Aim: </strong>The aim of this study was to determine the level of nutritional knowledge of postpartum women living in Türkiye and the factors affecting their nutritional behaviors.</p><p><strong>Methods: </strong>Women who were in the first 6 months postpartum and breastfeeding in Türkiye were reached through social media. A total of 264 volunteer women were included in the study. Participant introduction form, breastfeeding mother nutrition knowledge level measurement form, identification of factors affecting nutrition form, and informed consent form were applied to the women.</p><p><strong>Results: </strong>The majority of mothers (60.2%) reported not receiving nutritional information during the puerperium. A significant proportion (45.1%) indicated experiencing pressure from their social environment regarding dietary practices, which negatively affected their mental well-being (69.7%) and led to changes in their dietary habits (30.3%). Sleep disturbances were reported to impact dietary behavior by 67.6% of mothers, primarily causing them to skip main meals (35.4%). Additionally, 44.7% of participants noted that home visits influenced their nutritional practices, often leading to the consumption of puerperal sherbet and calorie-dense foods such as pastries and desserts. Mothers who received education about puerperium nutrition demonstrated significantly higher levels of accurate nutritional knowledge (P = 0.011), highlighting the importance of targeted educational interventions.</p><p><strong>Conclusion: </strong>While nutrition education programs for mothers are organized by health professionals in the postpartum period, importance should be given to increasing the awareness and consciousness levels of the mother's close circle.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"687-694"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Hearing Threshold and Pattern of Tympanograms of Sickle Cell Disease Patients in Calabar, Nigeria.","authors":"A G Adekanye, J B Okoi-Obuli, K O Akaba, A Umana, P M Francis","doi":"10.4103/njcp.njcp_572_24","DOIUrl":"10.4103/njcp.njcp_572_24","url":null,"abstract":"<p><strong>Background: </strong>Sickle cell disease patients often have high level of hearing threshold due to their susceptibility to pneumococcal infections, otitis media, and vaso-occlusive injury to the cochlea.</p><p><strong>Aims: </strong>This study aimed to determine the associations between the hemoglobin variants and hearing thresholds, hearing loss (HL), and tympanometry distributions in patients with sickle cell disease (SCD).</p><p><strong>Methods: </strong>This hospital-based study was conducted between September 2019 and September 2021. We recruited 110 confirmed SS and SC patients from adult and pediatric sickle cell clinics, Calabar sickle cell clubs, and 110 healthy controls (AA and AS). Structured questionnaires were used to interview the study population, and all of them underwent ear, nose, and throat examinations, tympanometry, and pure tone audiometry for those aged >5 years after obtaining informed consent and medical ethics committee approval. Data were analyzed using international business machine (IBM) corporation statistical product and service solution (SPSS) version 25 software. Descriptive analysis was performed using tables, graphs, and charts, whereas inferential statistics were obtained using the Chi-square test of independence or Fisher's exact test, t-test, or analysis of variance (ANOVA). Statistical significance was set at P value < 0.05.</p><p><strong>Results: </strong>The median ages of the SCD patients and their controls were 18 and 23 years, respectively. SCD patients have higher hearing thresholds, with 8.9% conductive loss, 4.5% unilateral mild mixed hearing loss, and 3.3% sensorineural hearing loss (SNHL) (2.0% among the controls; P value of 0.669), and more commonly in the right ear. The overall HL prevalence was 16.7% SCD patients and 8.0% controls (double; P value of 0.067). SNHL is mostly mild and unilateral in nature and affects only adults. Type B tympanogram was only reported in children with SCD.</p><p><strong>Conclusion: </strong>HbSS was the most prevalent genotype, with greater (double) HL than controls, affecting the right ear of males. HL patterns included mild conductive HL, mixed HL, and SNHL. SCD could be a risk factor for OME.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"764-772"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating Endotrophin as a Biomarker of Fibrosis in Chronic Liver Diseases.","authors":"H Eruzun, U Avcıoğlu, I Gören, Y C Ürkmez, Ö Küçükdemirci, Bşç Zorlu, E Isgandarov, M Ustaoğlu, T Ayyıldız, B Yıldırım, A Bektaş","doi":"10.4103/njcp.njcp_384_24","DOIUrl":"10.4103/njcp.njcp_384_24","url":null,"abstract":"<p><strong>Background: </strong>Liver fibrosis is a common consequence of most chronic inflammatory liver diseases and results in cirrhosis if left untreated. Therefore, it is important to detect early stages of fibrosis. Endotrophin, the cleavage product of collagen VI, plays a role in renal, cardiac, and hepatic fibrosis. In animal studies, expression of endotrophin results in hepatic inflammation and fibrosis.</p><p><strong>Aim: </strong>We investigated the association between serum endotrophin levels and severity of liver fibrosis in patients with chronic hepatitis B (CHB), autoimmune liver diseases (ALD), and metabolic-associated steatotic liver disease (MASLD).</p><p><strong>Methods: </strong>Blood samples were obtained from treatment-naive patients. Liver fibrosis was evaluated using the modified Knodell scoring system.</p><p><strong>Results: </strong>We included 85 patients (28 with CHB, 32 with ALD and 25 with MASLD). In the combined group endotrophin levels were significantly higher in patients with advanced fibrosis compared to mild fibrosis (P=0.006). However, in the CHB group endotrophin levels were significantly lower compared to the other groups (P<0.001). Further, there was no difference between mild and advanced fibrosis in the individual groups.</p><p><strong>Conclusions: </strong>Our preliminary data showed that endotrophin might be a clinically relevant biomarker for the assessment of liver fibrosis. However, etiology-specific larger-scale clinical studies are needed to determine the true utility of endotrophin as a biomarker in different chronic liver diseases.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"737-743"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thirty-Year-Old Rhinolith in a Female Adult at a Tertiary Institution.","authors":"R B Mgbe, A G Adekanye, M E Offiong, B C Onwughalu","doi":"10.4103/njcp.njcp_850_24","DOIUrl":"10.4103/njcp.njcp_850_24","url":null,"abstract":"<p><p>Rhinoliths are concrete salts of calcium, aluminum, and magnesium that form around exogenous or endogenous foreign bodies in the nasal cavity. Rhinoliths are most commonly asymptomatic and misdiagnosed. When symptomatic, they can present with nasal obstruction, foul breath, and bloody rhinorrhea. Rhinoscopy is the mainstay for rhinolith diagnosis. Plain radiographs or computerized tomography (CT) imaging aids in rhinolith diagnosis to determine their proper orientation. The definitive treatment is removal via manual or endoscopic maneuvers. We report the case of a 32-year-old female who was diagnosed with nasal polyps by a general practitioner because of persistent left-sided nasal obstruction, foul breath, and rhinorrhea for 6 months. The rhinolith was diagnosed via nasendoscopy and CT tomography of the paranasal sinuses, and its removal was performed under general anesthesia with the aid of an endoscope. The procedure was uneventful. The index patient was asymptomatic for 30 years, and was misdiagnosed with nasal polyps by a general practitioner. To the best of our knowledge, this is the first reported case of a rhinolith at our center.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"773-775"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Normal Pancreatic Stiffness Using 3T Magnetic Resonance Elastography.","authors":"L Karakaş, S Poçan, A Y Karkaş, Ş Şahin","doi":"10.4103/njcp.njcp_192_25","DOIUrl":"10.4103/njcp.njcp_192_25","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to establish the normal range of pancreatic stiffness in adults using 3T magnetic resonance elastography (MRE) and investigate how factors such as age, sex, pancreatic diameter, and anthropometric characteristics influence pancreatic stiffness.</p><p><strong>Aim: </strong>We aimed to provide data to the literature in determining the stiffness values of normal pancreatic tissue with 3T MRE.</p><p><strong>Methods: </strong>Patient demographic data, including age, sex, and body mass index (BMI), were collected. magnetic resonance imaging (MRI) and MRE parameters were extracted from the hospital's radiology database. Medical history, including liver or pancreatic conditions, was obtained from the patients and confirmed through electronic medical records.</p><p><strong>Results: </strong>The study included 54 patients, comprising 31 males (57.4%) and 23 females (42.6%), with a mean age of 35.8 ± 9.18 years. The average BMI was 24.73 ± 1.83 kg/m². The pancreatic diameters were 20.80 ± 2.13 cm (CC) and 19.93 ± 3.29 cm (AP). The mean pancreatic stiffness was 1587.09 ± 114.90 Pascals (Pa). No significant correlations were found between pancreatic stiffness and age (r = -0.128, P = 0.358), sex (r = -0.051, P = 0.716), BMI (r = -0.026, P = 0.850), pancreatic CC diameter (r = -0.090, P = 0.519), or AP diameter (r = 0.054, P = 0.701).</p><p><strong>Conclusion: </strong>This study provides reliable baseline values for normal pancreatic stiffness (1587.09 ± 114.90 Pa) using 3T MRE, which is essential for distinguishing normal from pathological tissue. These findings suggest that demographic and anatomical factors have little impact on pancreatic stiffness, supporting the potential of MRE in evaluating pancreatic diseases.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"751-757"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}