C I Nnamchi, C K Oranusi, M A Nwofor, J A Abiahu, T U Mbaeri, C O Onuigbo, E D Orakwe, E A Obiesie, U V Nwadi, O I Oranusi
{"title":"尼日利亚东南部膀胱出口梗阻患者慢性尿潴留、尿潴留量与肾功能的相关性","authors":"C I Nnamchi, C K Oranusi, M A Nwofor, J A Abiahu, T U Mbaeri, C O Onuigbo, E D Orakwe, E A Obiesie, U V Nwadi, O I Oranusi","doi":"10.4103/njcp.njcp_354_25","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Urinary retention (UR) can lead to both anatomical and functional derangement in the urinary system. Chronic kidney disease occurs when there is renal damage.</p><p><strong>Aim: </strong>This study aims to determine the relationship between chronic UR (CUR), retained urine volume, and renal function among men with chronic and acute-on-chronic UR.</p><p><strong>Methods: </strong>The study was a hospital-based prospective study of Nigerian men presenting with chronic or acute-on-chronic UR. Diagnosis of UR was made based on history and physical examination. The estimated glomerular filtration rate (eGFR) was calculated using the serum creatinine level. Retained urine volume was measured after an aseptic urethral catheterization. Spearman's rank correlation test was used for correlation analysis between CUR, retained urine volume, and renal function. A P value of < 0.05 was accepted as statistically significant.</p><p><strong>Results: </strong>Fifty-six men met the inclusion criteria. Most of the patients were in the age range of 80-89 years. A total of 20 (35.7%) had acute-on-chronic UR, while 36 (64.3%) had CUR. The mean retained urine volume was 1500 ± 748.0 mL and 1100 ± 515.0 mL for the chronic and acute-on-chronic UR groups, respectively. Obstructive nephropathy occurred in 88.6% of the participants with CUR. There was a significant negative relationship between the eGFR and the volume of retained urine (r = -0.397, P = 0.002).</p><p><strong>Conclusion: </strong>A high prevalence of obstructive nephropathy was observed among men with chronic and acute-on-chronic UR in this study.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 9","pages":"1020-1026"},"PeriodicalIF":0.7000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Correlation between Chronic Urinary Retention, Retained Urine Volume, and Renal Function in Men with Urinary Retention from Bladder Outlet Obstruction in Southeast Nigeria.\",\"authors\":\"C I Nnamchi, C K Oranusi, M A Nwofor, J A Abiahu, T U Mbaeri, C O Onuigbo, E D Orakwe, E A Obiesie, U V Nwadi, O I Oranusi\",\"doi\":\"10.4103/njcp.njcp_354_25\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Urinary retention (UR) can lead to both anatomical and functional derangement in the urinary system. 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引用次数: 0
摘要
背景：尿潴留（UR）可导致泌尿系统的解剖和功能紊乱。慢性肾脏疾病发生时，有肾脏损害。目的：本研究旨在确定慢性尿路（CUR）、尿潴留量和肾功能在慢性尿路和急性伴慢性尿路男性患者中的关系。方法：该研究是一项以医院为基础的前瞻性研究，研究对象为患有慢性或急性慢性尿路的尼日利亚男性。根据病史和体格检查作出诊断。估计肾小球滤过率（eGFR）计算使用血清肌酐水平。无菌导尿后测量留置尿量。采用Spearman秩相关检验分析尿潴留量、尿潴留量与肾功能之间的相关性。P值< 0.05为差异有统计学意义。结果：56名男性符合纳入标准。大多数患者年龄在80-89岁之间。共有20例（35.7%）患有急性合并慢性尿路，36例（64.3%）患有急性合并慢性尿路。慢性尿路组和急性合并慢性尿路组的平均尿量分别为1500±748.0 mL和1100±515.0 mL。梗阻性肾病发生率为88.6%，eGFR与尿潴留量呈显著负相关（r = -0.397, P = 0.002）。结论：在这项研究中，慢性和急性对慢性尿路患者中梗阻性肾病的患病率很高。
Correlation between Chronic Urinary Retention, Retained Urine Volume, and Renal Function in Men with Urinary Retention from Bladder Outlet Obstruction in Southeast Nigeria.
Background: Urinary retention (UR) can lead to both anatomical and functional derangement in the urinary system. Chronic kidney disease occurs when there is renal damage.
Aim: This study aims to determine the relationship between chronic UR (CUR), retained urine volume, and renal function among men with chronic and acute-on-chronic UR.
Methods: The study was a hospital-based prospective study of Nigerian men presenting with chronic or acute-on-chronic UR. Diagnosis of UR was made based on history and physical examination. The estimated glomerular filtration rate (eGFR) was calculated using the serum creatinine level. Retained urine volume was measured after an aseptic urethral catheterization. Spearman's rank correlation test was used for correlation analysis between CUR, retained urine volume, and renal function. A P value of < 0.05 was accepted as statistically significant.
Results: Fifty-six men met the inclusion criteria. Most of the patients were in the age range of 80-89 years. A total of 20 (35.7%) had acute-on-chronic UR, while 36 (64.3%) had CUR. The mean retained urine volume was 1500 ± 748.0 mL and 1100 ± 515.0 mL for the chronic and acute-on-chronic UR groups, respectively. Obstructive nephropathy occurred in 88.6% of the participants with CUR. There was a significant negative relationship between the eGFR and the volume of retained urine (r = -0.397, P = 0.002).
Conclusion: A high prevalence of obstructive nephropathy was observed among men with chronic and acute-on-chronic UR in this study.
期刊介绍：
The Nigerian Journal of Clinical Practice is a Monthly peer-reviewed international journal published by the Medical and Dental Consultants’ Association of Nigeria. The journal’s full text is available online at www.njcponline.com. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal makes a token charge for submission, processing and publication of manuscripts including color reproduction of photographs.
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