定量甲状腺显像对甲状腺功能亢进诊断的评价。

IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Nigerian Journal of Clinical Practice Pub Date : 2025-08-01 Epub Date: 2025-08-30 DOI:10.4103/njcp.njcp_39_25
A Cinar, D Cayir
{"title":"定量甲状腺显像对甲状腺功能亢进诊断的评价。","authors":"A Cinar, D Cayir","doi":"10.4103/njcp.njcp_39_25","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This study compared the dimensions of the thyroid gland measured by the scintigraphic method with those measured by the ultrasonographic method. Additionally, the correlation between the technetium uptake level of the thyroid gland and the thyroid-stimulating hormone (TSH) values of the patient was investigated.</p><p><strong>Aim: </strong>The aim of this study was to measure the uptake values and scintigraphic dimensions of the thyroid gland by using Technetium 99m pertechnetate and to investigate the relationship between these values in euthyroid and hyperthyroid states.</p><p><strong>Methods: </strong>The data of patients referred to the Nuclear Medicine Clinic at the Health Sciences University Gulhane Training and Research Hospital for thyroid scintigraphy (TS) between January 2019 and December 2021 were examined. In total, 100 patients (67 female and 33 male) aged 18-77 (mean ± SD: 42.3 ± 15.6) years were examined. According to the thyroid scintigraphic appearances, the patients were classified into five groups: normal thyroid gland, hypoactive nodular thyroid gland, hyperactive nodular thyroid gland, diffuse hyperplastic thyroid gland, and mixed nodular thyroid gland. The region of interest (ROI) covering both thyroid lobes was drawn. The ROI covering both submandibular glands and background activity was also drawn, and count measurements from these two areas were compared.</p><p><strong>Results: </strong>Following the thyroid scintigraphic evaluation of patients in the five groups, the following results were obtained: 13/100 (13%) were within normal ranges, 7/100 (7%) were hypoactive nodular, 31/100 (31%) were hyperactive nodular, 20/100 (20%) were diffuse hyperplasia, and 29/100 (29%) were mixed nodular. The thyroid/background activity ratio of cases reported as having a normoactive thyroid gland, with TSH values within normal limits, was calculated to be between 2.08 and 2.2 based on the scintigraphic images included in the study.</p><p><strong>Conclusions: </strong>Tc-99m pertechnetate TS is a reliable method that can be used for various nuclear medicine applications, such as evaluating thyroid gland morphology and calculating its size.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 8","pages":"962-968"},"PeriodicalIF":0.7000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Quantitative Thyroid Scintigraphy for Diagnosis of Hyperthyroidism.\",\"authors\":\"A Cinar, D Cayir\",\"doi\":\"10.4103/njcp.njcp_39_25\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This study compared the dimensions of the thyroid gland measured by the scintigraphic method with those measured by the ultrasonographic method. Additionally, the correlation between the technetium uptake level of the thyroid gland and the thyroid-stimulating hormone (TSH) values of the patient was investigated.</p><p><strong>Aim: </strong>The aim of this study was to measure the uptake values and scintigraphic dimensions of the thyroid gland by using Technetium 99m pertechnetate and to investigate the relationship between these values in euthyroid and hyperthyroid states.</p><p><strong>Methods: </strong>The data of patients referred to the Nuclear Medicine Clinic at the Health Sciences University Gulhane Training and Research Hospital for thyroid scintigraphy (TS) between January 2019 and December 2021 were examined. In total, 100 patients (67 female and 33 male) aged 18-77 (mean ± SD: 42.3 ± 15.6) years were examined. According to the thyroid scintigraphic appearances, the patients were classified into five groups: normal thyroid gland, hypoactive nodular thyroid gland, hyperactive nodular thyroid gland, diffuse hyperplastic thyroid gland, and mixed nodular thyroid gland. The region of interest (ROI) covering both thyroid lobes was drawn. The ROI covering both submandibular glands and background activity was also drawn, and count measurements from these two areas were compared.</p><p><strong>Results: </strong>Following the thyroid scintigraphic evaluation of patients in the five groups, the following results were obtained: 13/100 (13%) were within normal ranges, 7/100 (7%) were hypoactive nodular, 31/100 (31%) were hyperactive nodular, 20/100 (20%) were diffuse hyperplasia, and 29/100 (29%) were mixed nodular. The thyroid/background activity ratio of cases reported as having a normoactive thyroid gland, with TSH values within normal limits, was calculated to be between 2.08 and 2.2 based on the scintigraphic images included in the study.</p><p><strong>Conclusions: </strong>Tc-99m pertechnetate TS is a reliable method that can be used for various nuclear medicine applications, such as evaluating thyroid gland morphology and calculating its size.</p>\",\"PeriodicalId\":19431,\"journal\":{\"name\":\"Nigerian Journal of Clinical Practice\",\"volume\":\"28 8\",\"pages\":\"962-968\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nigerian Journal of Clinical Practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4103/njcp.njcp_39_25\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nigerian Journal of Clinical Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/njcp.njcp_39_25","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/30 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

摘要

背景:本研究比较了闪烁法和超声法测量甲状腺的尺寸。此外,我们还研究了患者甲状腺的锝摄取水平与促甲状腺激素(TSH)值之间的相关性。目的:本研究的目的是用99m高锝酸盐测定甲状腺的摄取值和成像尺寸,并探讨这些值在甲状腺功能正常和甲状腺功能亢进状态下的关系。方法:分析2019年1月至2021年12月在健康科学大学Gulhane培训研究医院核医学门诊进行甲状腺显像(TS)检查的患者资料。共检查100例患者,其中女性67例,男性33例,年龄18-77岁(平均±SD: 42.3±15.6)岁。根据甲状腺显像表现将患者分为正常甲状腺、低活动性结节性甲状腺、高活动性结节性甲状腺、弥漫性甲状腺增生性甲状腺和混合性甲状腺五组。绘制覆盖两个甲状腺叶的感兴趣区域(ROI)。绘制了覆盖下颌下腺和背景活动的ROI,并比较了这两个区域的计数测量结果。结果:对五组患者进行甲状腺显像评估,结果如下:13/100(13%)在正常范围内,7/100(7%)为低活动性结节,31/100(31%)为高活动性结节,20/100(20%)为弥漫性增生,29/100(29%)为混合性结节。根据研究中包含的闪烁图像,甲状腺功能正常且TSH值在正常范围内的病例的甲状腺/背景活动比计算为2.08至2.2之间。结论:Tc-99m高技术酸盐TS是一种可靠的方法,可用于各种核医学应用,如评估甲状腺形态和计算其大小。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Quantitative Thyroid Scintigraphy for Diagnosis of Hyperthyroidism.

Background: This study compared the dimensions of the thyroid gland measured by the scintigraphic method with those measured by the ultrasonographic method. Additionally, the correlation between the technetium uptake level of the thyroid gland and the thyroid-stimulating hormone (TSH) values of the patient was investigated.

Aim: The aim of this study was to measure the uptake values and scintigraphic dimensions of the thyroid gland by using Technetium 99m pertechnetate and to investigate the relationship between these values in euthyroid and hyperthyroid states.

Methods: The data of patients referred to the Nuclear Medicine Clinic at the Health Sciences University Gulhane Training and Research Hospital for thyroid scintigraphy (TS) between January 2019 and December 2021 were examined. In total, 100 patients (67 female and 33 male) aged 18-77 (mean ± SD: 42.3 ± 15.6) years were examined. According to the thyroid scintigraphic appearances, the patients were classified into five groups: normal thyroid gland, hypoactive nodular thyroid gland, hyperactive nodular thyroid gland, diffuse hyperplastic thyroid gland, and mixed nodular thyroid gland. The region of interest (ROI) covering both thyroid lobes was drawn. The ROI covering both submandibular glands and background activity was also drawn, and count measurements from these two areas were compared.

Results: Following the thyroid scintigraphic evaluation of patients in the five groups, the following results were obtained: 13/100 (13%) were within normal ranges, 7/100 (7%) were hypoactive nodular, 31/100 (31%) were hyperactive nodular, 20/100 (20%) were diffuse hyperplasia, and 29/100 (29%) were mixed nodular. The thyroid/background activity ratio of cases reported as having a normoactive thyroid gland, with TSH values within normal limits, was calculated to be between 2.08 and 2.2 based on the scintigraphic images included in the study.

Conclusions: Tc-99m pertechnetate TS is a reliable method that can be used for various nuclear medicine applications, such as evaluating thyroid gland morphology and calculating its size.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nigerian Journal of Clinical Practice
Nigerian Journal of Clinical Practice MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
275
审稿时长
4-8 weeks
期刊介绍: The Nigerian Journal of Clinical Practice is a Monthly peer-reviewed international journal published by the Medical and Dental Consultants’ Association of Nigeria. The journal’s full text is available online at www.njcponline.com. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal makes a token charge for submission, processing and publication of manuscripts including color reproduction of photographs.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信