Nicotine & Tobacco Research最新文献

{"title":"Correction to: Analysis of Impact of Province-Level Smokefree Policies on Smoking Status and Indoor Second-Hand Smoke Exposure in Indonesia Between 2013 and 2018 via a Difference-in-Differences Approach.","authors":"","doi":"10.1093/ntr/ntaf199","DOIUrl":"https://doi.org/10.1093/ntr/ntaf199","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145239444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tobacco Product Use and Type by Military Veteran Status: Findings from the National Health Interview Survey, 2021-2023.","authors":"Jennifer Cornacchione Ross, Rime Jebai, Joshua C Gray, Anthony J Rosellini, Melissa A Little, Rachel Sayko Adams","doi":"10.1093/ntr/ntaf142","DOIUrl":"https://doi.org/10.1093/ntr/ntaf142","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco use is common among United States Veterans; however, most research is a decade old, does not examine the range of tobacco products, nor consider the role of Veteran-specific factors (eg, Veterans Health Administration [VHA] health insurance).</p><p><strong>Aims and methods: </strong>We examined tobacco use (current, former) by Veteran status using a national sample; and among Veterans, associations between VHA health insurance and VA-connected service disability status and tobacco use. We used annual cross-sectional datasets (2021-2023) from the National Health Interview Survey (n = 78 277). Weighted multivariable multinomial logistic regression models examined the relationship between Veteran status and current and former: (1) tobacco use (ie, cigarettes, cigars, pipes, e-cigarettes, smokeless; any); (2) combustible tobacco use; and (3) polytobacco use, adjusting for sociodemographics, health status, and survey year. We replicated all models within the Veteran sample, adding variables for VHA health insurance status and VA-connected service disability status.</p><p><strong>Results: </strong>Veterans (7.9% of the sample) had higher odds of all current and former tobacco outcomes, with the highest adjusted odds ratios (aOR) for current use of: cigars (aOR = 1.97), pipes (aOR = 1.70), polytobacco use (aOR = 1.55), and cigarettes (aOR = 1.41), compared to non-Veterans. In Veteran models, those with VHA health insurance had higher odds of current cigarette (aOR = 1.47) and combustible tobacco use (aOR = 1.28).</p><p><strong>Conclusions: </strong>Veterans were more likely to report current tobacco use compared to non-Veterans, with variation in odds by product type. Veterans who use the VHA for healthcare have increased odds for cigarette and combustible tobacco use. Clinicians working with Veterans should routinely screen for all tobacco products.</p><p><strong>Implications: </strong>Veterans have historically used tobacco products at higher rates compared to non-Veterans, partially due to the normalization of use within military culture. Existing research is dated and does not examine the association of Veterans status with individual product types, including newer products. These findings highlight new patterns of use, including high prevalence of cigar use, and opportunities to educate Veterans, both within and outside the VHA, about the relative harms of different tobacco products and to implement culturally-informed cessation programs for Veterans.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Act Now to Save Science: The Importance of Tobacco Health Equity Research.","authors":"Jin E Kim-Mozeleski, Erin L Mead-Morse, Andy S L Tan, Sarah Cha, Irene Pericot-Valverde, Dana M Carroll, Erika S Trapl, Josephine T Hinds, Sandra J Japuntich, Andrea H Weinberger","doi":"10.1093/ntr/ntaf186","DOIUrl":"https://doi.org/10.1093/ntr/ntaf186","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cessation of Smoking Trial in the Emergency Department (COSTED): Long-Term Follow-Up of a Randomized Controlled Trial.","authors":"Ian Pope, Zuzanna Halicka, Lucy Clark, Susan Stirling, Allan Clark, Caitlin Notley","doi":"10.1093/ntr/ntaf200","DOIUrl":"https://doi.org/10.1093/ntr/ntaf200","url":null,"abstract":"<p><strong>Introduction: </strong>Emergency Departments (EDs) offer a valuable opportunity to deliver smoking cessation interventions. Long-term abstinence confers the maximum health benefits.</p><p><strong>Methods: </strong>Adults attending UK EDs who currently smoked were randomized to intervention (brief advice, e-cigarette and referral to local stop smoking services) or control (contact details for local stop smoking services). Participants were followed up at 1, 3 and 6 months as part of the main trial. Participants who consented to long term follow-up were also contacted at approximately 18 months post randomization. For an \"all participants\" analysis those who did not consent to long-term follow-up had their smoking status set at the value of the 6 month outcome. Those who did not respond were assumed to be smoking.</p><p><strong>Results: </strong>Long-term follow-up occurred between 14 and 22 months, mean = 18 months. Long term follow-up for those who consented to this was 35% in the intervention group (n = 145) and 34% in the control group (n = 143). For those who consented to long term follow-up self-reported 7-day abstinence at 18 months was 12.8% in the intervention group (n = 53) and 8.33% in the control group (n = 35) (RR = 1.56, 95% CI 1.04-2.32, p=.031). For all participants self-reported 7-day abstinence at long term follow-up was 13.8% in the intervention group (n = 67) and 8.6% in the control group (n = 42) (RR = 1.61, 95% CI 1.12-2.31, p=.010).</p><p><strong>Conclusions: </strong>Adults who smoke attending the ED who received a smoking cessation intervention were significantly more likely to report abstinence 18 months after randomization.</p><p><strong>Implications: </strong>Emergency Departments should be considered as a location for smoking cessation interventions in order to increase long term abstinence.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperalgesia and Neuropathic Pain Mechanism in Rodent Models of Cigarette Smoking- and Nicotine-Induced Precipitated Withdrawal Study.","authors":"Vishakha Shrimali, Deepsi Rathore, Aanchal Joshi, Nibedita Naha","doi":"10.1093/ntr/ntaf153","DOIUrl":"https://doi.org/10.1093/ntr/ntaf153","url":null,"abstract":"<p><strong>Introduction: </strong>Quitting smoking, or nicotine deprivation, is associated with withdrawal symptoms, including increased pain sensitivity and hyperalgesia through poorly managed current therapies, thus highlighting the need to improve our knowledge of pain mechanisms and their management during nicotine withdrawal, or smoking cessation states.</p><p><strong>Methods: </strong>In this context, the present study investigates the role of brain-derived neurotrophic factor (BDNF), inflammation, and redox balance in the cerebral cortex of adult rats exposed to oral nicotine and passive cigarette smoking through a whole-body inhalation chamber for short- and long-term exposure, where doses closely mimic the human smoking scenario. A subset of the exposure group received a single dose of mecamylamine hydrochloride, a nicotine acetylcholine receptor blocker, to evaluate the precipitated withdrawal effects as contributors to hyperalgesia and neuropathic pain.</p><p><strong>Results: </strong>The results reveal that nicotine/cigarette smoking induces hyperalgesia, lowers pain tolerance, and upregulates BDNF expression in adult rats as compared to the unexposed healthy controls. Mecamylamine mitigates the negative effects of nicotine by modulating neural circuits of the cerebral cortex involved in pain and inflammation. Specifically, mecamylamine changes cytokine dynamics by upregulating interleukin-6 (IL-6) expression, restoring redox balance, and downregulating BDNF and its receptor, Trk-β, in the cerebral cortex, thereby exacerbating pain sensitivity and ameliorating pain tolerance.</p><p><strong>Conclusion: </strong>The BDNF-Trk-β/IL-6 cascade in the cerebral cortex may prevent nicotine relapse by alleviating hyperalgesia and neuropathic pain during smoking cessation/nicotine withdrawal.</p><p><strong>Implications: </strong>Tobacco use is almost double in chronic pain patients, where opioid-based drugs cause more addiction burden. The study provides an insight into potential non-opioid therapeutic strategies targeting the BDNF-Trk-β/IL-6 cascade in the cerebral cortex, the higher center of behavioral activities, using adult rodent models where nicotine doses closely mimic the human smoking situation, including passive cigarette smoking and oral nicotine use. The data of the study may be useful for neuropathic pain management during nicotine withdrawal/smoking cessation and quitting efforts.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimum legal sales age for e-cigarettes: A qualitative study on the implementation of model policy components.","authors":"Ginny Chadwick, Gina R Kruse, Maeve Stover, Cameron Alyssa Reitan, Victoria Lopez Mendez, Hattie M Kahl, Douglas E Levy","doi":"10.1093/ntr/ntaf197","DOIUrl":"https://doi.org/10.1093/ntr/ntaf197","url":null,"abstract":"<p><strong>Introduction: </strong>All 50 states have e-cigarette minimum legal sales age (MLSA) policies. In 2019, national tobacco control organizations released a model MLSA policy providing guidance on how tobacco policies should be structured to effectively prevent underage sales. We explored state e-cigarette MLSA implementation in relation to the model policy.</p><p><strong>Methods: </strong>Key informant (KI) interviews were conducted with state personnel involved in MLSA implementation from a purposive sample of states. Informants were asked about policy components, implementation facilitators, challenges, and processes, based on Bullock's determinants of policy implementation framework. Interviews were coded by framework domains and analyzed for themes related to implementing model policy components. Key components included product definitions, age restrictions, licensure, funding, education, preemption, ID verification, signage, enforcement agency and protocols, compliance checks, penalties, and prosecution.</p><p><strong>Results: </strong>Between April 2023 and July 2024, 24 MLSA interviews were conducted with 32 KIs from 23 states, yielding 4589 coded passages. KIs reported engaging with model policy components during the implementation process, though states varied in their alignment with the model's recommendations, with areas of more common deviation including penalty structures, whether clerks or retailers were penalized, and required compliance checks. Several implementation factors absent from the model also emerged as important, including online sales, license transfer, \"decoy buy\" products, complaint-driven compliance checks, and product disposal.</p><p><strong>Conclusion: </strong>States' e-cigarette MLSA policy implementation experiences in relation to model policy recommendations identified areas where states could improve (e.g., penalties) and novel issues (e.g., online sales) whose implementation is worthy of ongoing attention.</p><p><strong>Implications: </strong>Insights from the state MLSA implementation experiences should inform advocates, bureaucrats, and elected officials about potential solutions to implementation barriers for e-cigarette MLSA. Findings highlight implementation facilitators and identify existing model policy components that may be improved in future guidance. Key elements for revising state policies and/or the model include shifting penalties from clerks to retailers, setting a minimum number of compliance checks, coordinating compliance programs, reconsidering criminal penalty structures, regulating online sales, preventing illegitimate license transfers, establishing complaint-driven enforcement, and requiring the inclusion of e-cigarette products in a minimum percentage of decoy buys.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145177031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: The World Conference on Tobacco Control - Mixed Perspectives and Controversies.","authors":"Lisa Bero, Joanna E Cohen","doi":"10.1093/ntr/ntaf196","DOIUrl":"https://doi.org/10.1093/ntr/ntaf196","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cigarette Smoking with Serious Mental Illness: US Provider and Veteran Beliefs About How to Quit.","authors":"Corinne N Kacmarek, Eliana J Trikeriotis, Richard W Goldberg, Karen Besterman-Dahan","doi":"10.1093/ntr/ntaf198","DOIUrl":"https://doi.org/10.1093/ntr/ntaf198","url":null,"abstract":"<p><strong>Introduction: </strong>Veterans with serious mental illness (SMI) have high cigarette smoking rates and want to quit, but mental health providers are often reluctant to treat smoking. This study compared how providers and veterans in a United States Veteran Affairs Medical Center (VA) SMI clinics view smoking and treatment.</p><p><strong>Methods: </strong>20 SMI providers and 20 veterans with SMI who smoked cigarettes were interviewed. A rapid evaluation matrix approach was used to code interviews based on the Theory of Planned Behavior (attitudes, self-efficacy, and norms). This paper focuses on themes identified in the attitudes and self-efficacy domains.</p><p><strong>Results: </strong>Veterans had high interest in quitting smoking but low self-efficacy to quit. In regards to attitudes, veterans had specific beliefs about how and when to quit. Provider attitudes involved anticipating mixed interest in quitting among their veterans and anticipating low quit rates. Eighteen (90%) veterans were at least contemplating quitting. Many providers interpreted ambivalence about quitting as low readiness to quit and viewed the smoking/return-to-smoking cycle of addiction as an indicator that veterans with SMI could not quit. Veterans also believed they could not quit until they were \"ready\" or strong enough to do so, which impeded initiating smoking discussion with providers.</p><p><strong>Conclusion: </strong>Providers and veterans share unhelpful attitudes about quitting smoking, which discouraged treatment and reinforced unhelpful attitudes. These qualitative findings shed light on the underlying mechanisms of infrequent tobacco treatment in mental health settings via the Theory of Planned Behavior to guide efforts to improve reach of tobacco treatment in these settings.</p><p><strong>Implications: </strong>Comparing the perspectives of providers and veterans from the same setting is a rare contribution to tobacco treatment literature. Provider and veteran attitudes about quitting smoking interacted and led smoking to persist unaddressed despite veteran interest in quitting. Providers may benefit from education about how to effectively treat smoking to dispel myths that impede treatment and feel more comfortable integrating smoking treatment into routine care.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Spanish-language Adaptation of the Brief Wisconsin Inventory of Smoking Dependence Motives Among Mexican and Mexican-American Adults Who Smoke.","authors":"Jose E Velasquez, Yessenia Castro, Zully C Guerra, Tatiana Londoño, John R Moore, Nazanin M Heydarian","doi":"10.1093/ntr/ntaf042","DOIUrl":"10.1093/ntr/ntaf042","url":null,"abstract":"<p><strong>Introduction: </strong>The smoking pattern of Latino smokers differs from non-Latino white smokers such that physical dependence may not be a strong motivator for smoking among Latinos. Multidimensional measures of dependence may be more useful, but there is a lack of psychometrically sound multidimensional Spanish-language measures. This study evaluated the psychometric properties of a Spanish-language adaptation of the Brief Wisconsin Inventory of Dependence Motives (Brief WISDM) for use among Spanish-speaking Latino smokers in the United States.</p><p><strong>Methods: </strong>Two hundred and eighty-seven Spanish-speaking Mexican-origin smokers in the United States responded to a revised set of Spanish Brief WISDM items. Confirmatory factor analyses and model trimming procedures were conducted with 144 participants randomly selected from the sample. The resulting scale was replicated with the remaining 143 participants. Tests of concurrent validity examined each subscale's ability to statistically predict relevant smoking patterns.</p><p><strong>Results: </strong>Model trimming resulted in a 19-item, six-factor scale with acceptable fit (χ2 = 227.03, p < .0001; RMSEA = .07, CFI = .93, TLI = 0.92, SRMR = 0.05). The final model retained factors Automaticity, Craving, Social/Environmental Goads, Taste, and Weight Control. Items from Affective Enhancement and Cognitive Enhancement were combined to form one factor. Concurrent validity was largely supported in both samples.</p><p><strong>Conclusions: </strong>This study helps address the need for a valid and reliable multidimensional Spanish language measure of commercial tobacco dependence.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"1729-1738"},"PeriodicalIF":3.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"American Indian Persons' Perspectives on Various Smoking Cessation Aids and Approaches: A Community-Engaged Qualitative Research Study.","authors":"Dana Mowls Carroll, Julie Ntegeye, Lou Moerner, Claradina Soto, Dorothy Hatsukami, Antony Stately, Dylan Jennings, Wyatt Pickner","doi":"10.1093/ntr/ntaf032","DOIUrl":"10.1093/ntr/ntaf032","url":null,"abstract":"<p><strong>Introduction: </strong>Increasing smoking cessation among American Indian (AI) persons is a critical equity goal.</p><p><strong>Aims and methods: </strong>During 2022, AI persons (N = 46) were interviewed on perceptions of existing and novel cessation approaches. Intention to use each approach was assessed and questions started with \"cold turkey\" and then queried about the following: nicotine patches, gum, lozenges (NRT); prescription medications; plant-based medications; personalized medicine; e-cigarettes; and nicotine reduction standard (NRS).</p><p><strong>Results: </strong>Perspectives informed the identification of six crosscutting themes which were (a) environmental constraints, (b) addictiveness and side effects, (c) effectiveness of approach, (d) interpersonal influence, (e) duration or requirements of approach, and (f) novelty. Plant-based medications were viewed as natural, less likely to cause side effects, and aligned with AI cultures. Regarding NRT, many participants talked about positive word-of-mouth but noted concerns about effectiveness, side effects, and price. Regarding personalized medicine, many indicated curiosity, but some noted it would delay treatment and was too extreme to share a sample. Common perspectives for cold turkey were its drug-free nature and cost savings, but some noted it does not address cravings. Regarding the NRS, many were supportive, although some were concerned with compensatory smoking and what else remains in the cigarettes.</p><p><strong>Conclusions: </strong>Themes translated to the greatest proportion of participants stating they would use plant-based medications followed by NRT and personalized medicine. Fewer participants reported intent to use prescription medications and e-cigarettes which reflect greater concerns with these approaches.</p><p><strong>Implications: </strong>Results can inform tribal and other public health programming and communication efforts to increase smoking cessation among AI persons and help drive down disparities.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"1721-1728"},"PeriodicalIF":3.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}