Nutrition Research and Practice最新文献

筛选
英文 中文
Liquid collagen from freshwater fish skin ameliorates hydration, roughness and elasticity in photo-aged skin: a randomized, controlled, clinical study. 淡水鱼皮液态胶原蛋白改善光老化皮肤的水合作用、粗糙度和弹性:一项随机对照临床研究。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-06-01 Epub Date: 2024-05-17 DOI: 10.4162/nrp.2024.18.3.357
Joong Su Lee, Yeo Cho Yoon, Ju Myung Kim, Yun-Ho Kim, Young-Hee Kang, Yong Chul Shin
{"title":"Liquid collagen from freshwater fish skin ameliorates hydration, roughness and elasticity in photo-aged skin: a randomized, controlled, clinical study.","authors":"Joong Su Lee, Yeo Cho Yoon, Ju Myung Kim, Yun-Ho Kim, Young-Hee Kang, Yong Chul Shin","doi":"10.4162/nrp.2024.18.3.357","DOIUrl":"10.4162/nrp.2024.18.3.357","url":null,"abstract":"<p><strong>Background/objectives: </strong>Collagen is commonly used in diverse forms as a functional component in skincare products. On the other hand, the effects of collagen on human skin are controversial. Dietary collagen hydrolysates from freshwater <i>Pangasius hypophthalmus</i> fish skin ameliorated photo-aged skin of hairless mice. This study conducted a randomized, double-blind, placebo-controlled clinical trial to determine if liquid fish collagen (Collagen-Tripep20™, Tripep20) as a drink strengthens skin health and quality.</p><p><strong>Subjects/methods: </strong>In this clinical trial, 85 subjects aged 35-60 yrs were diagnosed with photo-aged skin. Eighty-five subjects were randomized to receive either Tripep20 (n = 44) or placebo (n = 41). Seventy-eight subjects fully participating for a 12-week period consumed 1,000 mg of Tripep20 (n = 41) or placebo (n = 37) in a 50-mL bottle as a daily drink. The intend-to-treat and per-protocol populations were 85 and 78, respectively. Skin hydration, wrinkles, and elasticity were assessed at 0 (baseline), 6, and 12 weeks during the study period.</p><p><strong>Results: </strong>Skin hydration in the Tripep20 group was significantly higher from 6 weeks (<i>P</i> < 0.001) than the baseline. After 12 weeks, the Crow's-feet visual score and skin roughness (R<sub>a</sub>, R<sub>q</sub>, and R<sub>max</sub>) were significantly improved in the Tripep20 group than in the placebo group (<i>P</i> < 0.05). Consuming liquid collagen Tripep20 greatly enhanced skin elasticity (Gross R2, Net R5, and Biological elasticity R7) in 6 weeks compared to the placebo group. The Tripep20 group showed a significant increase in skin elasticity from the baseline after 6 and 12 weeks (<i>P</i> < 0.001). Neither abnormal symptoms nor adverse events were encountered during the study period in subjects ingesting Tripep20 or placebo. The changes in parameters related to hematology and clinical chemistry were within the normal ranges.</p><p><strong>Conclusion: </strong>Oral consumption of liquid collagen Tripep20 was safe and well-tolerated. The results of this study show that freshwater fish-derived liquid collagen Tripep20 can be used as a healthy functional food ingredient to improve skin moisturizing, anti-wrinkling, and elasticity in an aging population.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 3","pages":"357-371"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kaempferol ameliorates metabolic syndrome by inhibiting inflammation and oxidative stress in high-fat diet-induced obese mice. 山奈酚通过抑制高脂饮食诱导的肥胖小鼠的炎症和氧化应激,改善代谢综合征。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-06-01 Epub Date: 2024-04-22 DOI: 10.4162/nrp.2024.18.3.325
Su-Kyung Shin, Eun-Young Kwon
{"title":"Kaempferol ameliorates metabolic syndrome by inhibiting inflammation and oxidative stress in high-fat diet-induced obese mice.","authors":"Su-Kyung Shin, Eun-Young Kwon","doi":"10.4162/nrp.2024.18.3.325","DOIUrl":"10.4162/nrp.2024.18.3.325","url":null,"abstract":"<p><strong>Background/objectives: </strong>Kaempferol (Ka) is one of the most widely occurring flavonoids found in large amounts in various plants. Ka has anti-obesity, antioxidant, and anti-inflammatory effects. Despite the numerous papers documenting the efficacy of Ka, some controversy remains. Therefore, this study examined the impact of Ka using 3T3-L1 and high-fat diet-induced obese mice.</p><p><strong>Materials/methods: </strong>3T3-L1 cells were treated with 50 μM Ka from the initiation of 3T3-L1 differentiation at D0 until the completion of differentiation on D8. Thirty male mice (C57BL/6J, 4 weeks old) were divided into 3 groups: normal diet (ND), high-fat diet (HFD), and HFD + 0.02% (w/w) Ka (Ka) group. All mice were fed their respective diets <i>ad libitum</i> for 16 weeks. The mice were sacriced, and the plasma and hepatic lipid levels, white adipose tissue weight, hepatic glucose level, lipid level, and antioxidant enzyme activities were analyzed, and immunohistochemistry staining was performed.</p><p><strong>Results: </strong>Ka suppressed the hypertrophy of 3T3-L1 cells, and the Ka-supplemented mice showed a significant decrease in perirenal, retroperitoneal, mesenteric, and subcutaneous fat compared to the HFD group. Ka supplementation in high-fat diet-induced obese mice also improved the overall blood lipid concentration (total cholesterol, non-high-density lipoprotein-cholesterol, phospholipids, and apolipoprotein B). Ka supplementation in high-fat-induced obesity mice reduced hepatic steatosis and insulin resistance by modulating the hepatic lipid (glucose-6-phosphate dehydrogenase, fatty acid synthase, malic enzyme, phosphatidate phosphohydrolase, and β-oxidation) activities and glucose (glucokinase, phosphoenolpyruvate carboxykinase, and G6pase)-regulating enzymes. Ka supplementation ameliorated the erythrocyte and hepatic mitochondrial H<sub>2</sub>O<sub>2</sub> and inflammation levels (plasma tumor necrosis factor-alpha, monocyte chemoattractant protein-1, interleukin-6, and interferon-gamma and fibrosis of liver and epididymal fat).</p><p><strong>Conclusion: </strong>Ka may be beneficial for preventing diet-induced obesity, inflammation, oxidative stress, and diabetes.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 3","pages":"325-344"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Analysis of dietary behavior and intake related to glycemic control in patients with type 2 diabetes aged 30 years or older in Korea: Utilizing the 8th Korea National Health and Nutrition Examination Survey (2019-2021). 勘误:韩国 30 岁及以上 2 型糖尿病患者与血糖控制相关的饮食行为和摄入量分析:利用第八次韩国国民健康与营养调查(2019-2021年)。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-06-01 Epub Date: 2024-05-24 DOI: 10.4162/nrp.2024.18.3.446
Jin-Ah Seok, Yeon-Kyung Lee
{"title":"Erratum: Analysis of dietary behavior and intake related to glycemic control in patients with type 2 diabetes aged 30 years or older in Korea: Utilizing the 8th Korea National Health and Nutrition Examination Survey (2019-2021).","authors":"Jin-Ah Seok, Yeon-Kyung Lee","doi":"10.4162/nrp.2024.18.3.446","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.3.446","url":null,"abstract":"<p><p>[This corrects the article on p. 239 in vol. 18, PMID: 38584808.].</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 3","pages":"446-450"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationships among tooth loss, prefrailty, and dietary patterns in community-dwelling older Japanese females: a cross-sectional study. 在社区居住的日本老年女性中,牙齿脱落、体质虚弱和饮食模式之间的关系:一项横断面研究。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-06-01 Epub Date: 2024-05-14 DOI: 10.4162/nrp.2024.18.3.387
Tatsumi Hayashi, Rumi Sato, Kazuo Tamura
{"title":"Relationships among tooth loss, prefrailty, and dietary patterns in community-dwelling older Japanese females: a cross-sectional study.","authors":"Tatsumi Hayashi, Rumi Sato, Kazuo Tamura","doi":"10.4162/nrp.2024.18.3.387","DOIUrl":"10.4162/nrp.2024.18.3.387","url":null,"abstract":"<p><strong>Background/objectives: </strong>Poor oral health has been predicted the development of frailty and sarcopenia as well as the subsequent need for long-term care. This cross-sectional study examined the relationships among tooth loss, prefrailty, and dietary patterns in community-dwelling older Japanese females.</p><p><strong>Subjects/methods: </strong>Information on the number of teeth, food consumption, and lifestyle factors was collected from 271 participants aged ≥ 65 yrs using a questionnaire. The number of teeth was self-reported and classified into 2 groups: natural teeth ≥ 20 and natural teeth < 20. Prefrailty was assessed using the Japanese version of the Cardiovascular Health Study. Three dietary patterns (\"vegetables and dairy products\" [VD], \"rice and fish and shellfish\" [RF], and \"bread and beverages\") were adopted from a cluster analysis of the intakes of 20 foods evaluated using the Food Frequency Questionnaire. The odds ratios (ORs) for prefrailty and dietary patterns were calculated using a binary logistic regression analysis.</p><p><strong>Results: </strong>A total of 267 participants were analyzed, excluding those with frailty (n = 4). The rates of natural teeth < 20 and prefrailty were 57.3 and 37.4%, respectively. Natural teeth < 20 was positively correlated with prefrailty (OR, 4.66; 95% confidence interval [CI], 2.54-8.52) and inversely correlated with VD pattern (OR, 0.43; 95% CI, 0.27-0.69). Furthermore, both VD (OR, 0.38; 95% CI, 0.16-0.91) and RF (OR, 0.26; 95% CI, 0.11-0.62) patterns were inversely correlated with prefrailty.</p><p><strong>Conclusions: </strong>Maintaining the number of natural teeth ≥ 20 into old age plays an important role in preventing a prefrailty. The promotion of VD and RF dietary patterns has potential as an effective nutritional strategy for preventing tooth loss and prefrailty.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 3","pages":"387-399"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypoglycemic and hypolipidemic effects of unsaponifiable matter from okra seed in diabetic rats. 秋葵籽中的不皂化物对糖尿病大鼠的降血糖和降血脂作用
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-06-01 Epub Date: 2024-04-22 DOI: 10.4162/nrp.2024.18.3.345
Dongyeon Seo, Naeun Kim, Ahyeong Jeon, Jihyun Kwon, In-Hwan Baek, Eui-Cheol Shin, Junsoo Lee, Younghwa Kim
{"title":"Hypoglycemic and hypolipidemic effects of unsaponifiable matter from okra seed in diabetic rats.","authors":"Dongyeon Seo, Naeun Kim, Ahyeong Jeon, Jihyun Kwon, In-Hwan Baek, Eui-Cheol Shin, Junsoo Lee, Younghwa Kim","doi":"10.4162/nrp.2024.18.3.345","DOIUrl":"10.4162/nrp.2024.18.3.345","url":null,"abstract":"<p><strong>Background/objectives: </strong>Okra seed is a rich source of various nutritional and bioactive constituents, but its mechanism of action is still unclear. The aim of this study was to evaluated the effects on glucose uptake and serum lipid profiles of unsaponifiable matter (USM) from okra seed in adipocytes and diabetic animal models.</p><p><strong>Materials/methods: </strong>USM was prepared from okra seed powder by saponification. The contents of phytosterols and vitamin E in USM were measured. 3T3-L1 preadipocytes were cultured for 6 days with different concentrations of USM (0-200 μg/mL). The diabetic rats were administered with or without USM for 5 wk.</p><p><strong>Results: </strong>In the USM, the contents of phytosterols and vitamin E were 394.13 mg/g USM and 31.16 mg/g USM, respectively. USM showed no cytotoxicity and led to an approximately 1.4-fold increase in glucose uptake in 3T3-L1 adipocytes. The treatment of USM also increased the expressions of peroxisome proliferator-activated receptor-γ and glucose transporter-4 in a dose-dependent manner in adipocytes. The body weight change was not significantly different in all diabetic rats. However, blood glucose and the weights of liver and adipose tissues were significantly reduced compared to those in the control diabetic rats. Treatment with USM decreased the levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol compared to the control group. The USM group also showed significantly decreased atherogenic indices and cardiac risk factors.</p><p><strong>Conclusion: </strong>These results suggest that USM from okra seed improves the hypoglycemic and hypolipidemic effects in diabetic rats, and provides valuable information for improving the functional properties of okra seed.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 3","pages":"345-356"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malnutrition and its associated factors among community-dwelling older men living alone. 居住在社区的独居老人营养不良及其相关因素。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-06-01 Epub Date: 2024-05-23 DOI: 10.4162/nrp.2024.18.3.400
Gahye Kim, Minhwa Hwang, Seonghyeon Lee, Yeon-Hwan Park
{"title":"Malnutrition and its associated factors among community-dwelling older men living alone.","authors":"Gahye Kim, Minhwa Hwang, Seonghyeon Lee, Yeon-Hwan Park","doi":"10.4162/nrp.2024.18.3.400","DOIUrl":"10.4162/nrp.2024.18.3.400","url":null,"abstract":"<p><strong>Background/objectives: </strong>Older men who live alone are more vulnerable to poor nutrition. However, little attention has been paid to malnutrition among this population. This study aimed to examine malnutrition and its associated factors among community-dwelling older men living alone.</p><p><strong>Subjects/methods: </strong>This cross-sectional descriptive study used cohort data of community-dwelling older adults living alone in South Korea. A total of 230 older men aged 65 and over were included in this study. Nutritional status was assessed using the Mini Nutritional Assessment-Short Form. Multidimensional factors (sociodemographic, health-related, psychosocial, and lifestyle characteristics) were evaluated. Hierarchical logistic regression analyses were conducted to identify the malnutrition-related factors.</p><p><strong>Results: </strong>The prevalence of malnutrition was 32.2% in older men living alone. Low income (odds ratio [OR], 2.44; 95% confidence interval [CI], 1.01-5.90), polypharmacy (OR, 2.23; 95% CI, 1.16-4.28), suicidal ideation (OR, 2.13; 95% CI, 1.02-4.45), meal skipping (OR, 3.26; 95% CI, 1.60-6.64), and smoking (OR, 2.86; 95% CI, 1.43-5.73) were significantly associated with malnutrition.</p><p><strong>Conclusion: </strong>Malnutrition is a severe health problem in older men living alone. This study highlights the importance of comprehensive and tailored interventions to mitigate malnutrition among older men living alone.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 3","pages":"400-411"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Higher adherence to a Mediterranean-type diet is associated with reduced psychosocial stress levels in baby boomers: a cross-sectional study. 婴儿潮一代较高的地中海式饮食坚持率与较低的社会心理压力水平相关:一项横断面研究。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-04-01 Epub Date: 2024-03-27 DOI: 10.4162/nrp.2024.18.2.257
Eun-Hee Jang, Ranmi Jung, Seungmin Lee
{"title":"Higher adherence to a Mediterranean-type diet is associated with reduced psychosocial stress levels in baby boomers: a cross-sectional study.","authors":"Eun-Hee Jang, Ranmi Jung, Seungmin Lee","doi":"10.4162/nrp.2024.18.2.257","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.2.257","url":null,"abstract":"<p><strong>Background/objectives: </strong>This study investigated the relationship between adherence to the Mediterranean diet among Korean baby boomers and their levels of psychosocial stress.</p><p><strong>Subjects/methods: </strong>The study included 1,656 adults (889 men and 797 women) born between 1955 and 1963 who participated in the 2005-2006 survey of the community-based Korean Genome and Epidemiology Study (KoGES). The Mediterranean-type diet score (MTDS) was calculated from the semi-quantitative food frequency questionnaire (SQFFQ) data. The psychosocial stress levels were calculated using the psychosocial well-being index-short form (PWI-SF). Logistic regression analyses were performed to analyze the association between the MTDS (tertiles) and the prevalence of high psychosocial stress by gender.</p><p><strong>Results: </strong>The ranges of the MTDS tertile groups were T1 (20-33 points), T2 (34-37 points), and T3 (38-39 points) for men, T1 (20-33 points), T2 (34-37 points), and T3 (38-48 points) for women. In both men and women, the consumption of whole grains, potatoes, fruits, vegetables, legumes, and fish increased with higher MTDS, while the consumption of red meat and dairy products decreased (<i>P</i> for trend < 0.05). As MTDS score increased the intake of energy, fiber, vitamins, and minerals (<i>P</i> for trend < 0.05). Men in the highest MTDS tertile had a 41% lower odds ratio (OR) of high psychosocial stress compared with those in the lowest tertile (OR, 0.59; 95% confidence interval [CI], 0.38-0.91). Similarly, women in the highest tertile of the MTDS had a 39% lower OR of high psychosocial stress compared with those in the lowest tertile (OR, 0.61; 95% CI, 0.40-0.95).</p><p><strong>Conclusion: </strong>Promoting adherence to the Mediterranean diet among baby boomers may have a positive impact on reducing their levels of psychosocial stress.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 2","pages":"257-268"},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10995775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Rosa multiflora root extract on adipogenesis and lipogenesis in 3T3-L1 adipocytes and SD rat models. 多花蔷薇根提取物对 3T3-L1 脂肪细胞和 SD 大鼠模型中脂肪生成和脂肪生成的影响
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-04-01 Epub Date: 2024-03-21 DOI: 10.4162/nrp.2024.18.2.180
Kyoung Kon Kim, Hye Rim Lee, Sun Min Jang, Tae Woo Kim
{"title":"Effects of <i>Rosa multiflora</i> root extract on adipogenesis and lipogenesis in 3T3-L1 adipocytes and SD rat models.","authors":"Kyoung Kon Kim, Hye Rim Lee, Sun Min Jang, Tae Woo Kim","doi":"10.4162/nrp.2024.18.2.180","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.2.180","url":null,"abstract":"<p><strong>Background/objectives: </strong>Obesity is a major cause of metabolic disorders; to prevent obesity, research is ongoing to develop natural and safe ingredients with few adverse effects. In this study, we determined the anti-obesity effects of <i>Rosa multiflora</i> root extract (KWFD-H01) in 3T3-L1 adipocytes and Sprague-Dawley (SD) rats.</p><p><strong>Materials/methods: </strong>The anti-obesity effects of KWFD-H01in 3T3-L1 adipocytes and SD rats were examined using various assays, including Oil Red O staining, gene expression analyses, protein expression analyses, and blood biochemical analyses.</p><p><strong>Results: </strong>KWFD-H01 reduced intracellular lipid accumulation and inhibited the mRNA expression of peroxisome proliferator-activated receptor γ (PPARγ), cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins (C/EBPα), sterol regulatory element-binding transcription factor 1 (SREBP-1c), acetyl-CoA carboxylase (ACC), and fatty acid synthase (FAS) in 3T3-L1 cells. KWFD-H01 also reduced body weight, weight gain, and the levels of triglycerides, total and LDL-cholesterol, glucose, and leptin, while increasing high-density lipoprotein-cholesterol and adiponectin in SD rats. PPARγ, C/EBPα, SREBP-1c, ACC, and FAS protein expression was inhibited in the epididymal fat of SD rats.</p><p><strong>Conclusion: </strong>Overall, these results confirm the anti-obesity effects of KWFD-H01 in 3T3-L1 adipocytes and SD rats, indicating their potential as baseline data for developing functional health foods or pharmaceuticals to control obesity.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 2","pages":"180-193"},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10995778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of hypertension with noodle consumption among Korean adults based on the Health Examinees (HEXA) study. 基于健康体检者(HEXA)研究的韩国成年人高血压与吃面条的关系。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-04-01 Epub Date: 2024-03-29 DOI: 10.4162/nrp.2024.18.2.282
Suji Choi, Jungmin Park, Hyein Jung, Jiwon Jeong, Kyungjoon Lim, Sangah Shin
{"title":"Association of hypertension with noodle consumption among Korean adults based on the Health Examinees (HEXA) study.","authors":"Suji Choi, Jungmin Park, Hyein Jung, Jiwon Jeong, Kyungjoon Lim, Sangah Shin","doi":"10.4162/nrp.2024.18.2.282","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.2.282","url":null,"abstract":"<p><strong>Background/objectives: </strong>The prevalence of hypertension is increasing, and noodles have a high sodium content, so noodle consumption might be associated with a higher prevalence of hypertension. This study aimed to analyze the association between total and types of noodle intake and the risk of hypertension among Korean adults. Subjects aged 40-69 years were selected for this study.</p><p><strong>Subjects/methods: </strong>This study included 56,580 participants (18,246 men and 38,334 women) aged 40-69 years old from the Health Examinees study. Noodle and nutrient intakes were assessed using the food frequency questionnaire. Hypertension was diagnosed as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg or antihypertensive medication use. Cox proportional hazard models were used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for hypertension.</p><p><strong>Results: </strong>Higher noodle consumption was associated with increased hypertension among men (HR, 1.273; 95% CI, 1.166-1.390) and women (HR, 1.116; 95% CI, 1.038-1.199).</p><p><strong>Conclusion: </strong>We recommended reducing noodle intake and consuming vegetables and fruits to increase potassium intake, which can prevent vascular diseases.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 2","pages":"282-293"},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10995774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study on eating habits and mental health of Korean middle school students according to their bedtime across regions: using data from the 2020-2022 Korea Youth Risk Behavior Survey. 利用 2020-2022 年韩国青少年危险行为调查的数据,对韩国中学生的饮食习惯和心理健康进行跨地区就寝时间比较研究。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2024-04-01 Epub Date: 2024-03-27 DOI: 10.4162/nrp.2024.18.2.269
Sarim Kim, Jiyoung Jeong, Juyeon Kang, Jihye Kim, Yoon Jung Yang
{"title":"A comparative study on eating habits and mental health of Korean middle school students according to their bedtime across regions: using data from the 2020-2022 Korea Youth Risk Behavior Survey.","authors":"Sarim Kim, Jiyoung Jeong, Juyeon Kang, Jihye Kim, Yoon Jung Yang","doi":"10.4162/nrp.2024.18.2.269","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.2.269","url":null,"abstract":"<p><strong>Background/objectives: </strong>The objective of this study was to compare dietary habits and mental health among middle school students in urban and rural areas based on bedtime, and to provide evidence supporting appropriate bedtime for Korean middle school students in relation to their healthy dietary habits and mental well-being.</p><p><strong>Subjects/methods: </strong>The study population consisted of 25,681 second-year middle school students who participated in the Korea Youth Risk Behavior Survey in 2020-2022. Participants were asked about their bedtime and wake-up time during the past 7 days and were classified into five categories. The study compared the general characteristics, academic factors, dietary habits, and mental health of urban and rural students based on their bedtime.</p><p><strong>Results: </strong>Bedtime was found to be later in the following order: urban female students, rural female students, urban male students, and rural male students. As bedtime got later, the rates of smoking and alcohol consumption increased. Students who went to bed before 11 p.m. had lower academic performance, while rural male students who went to bed after 2 a.m. had lower academic performance. Later bedtime was associated with increased smartphone usage, skipping breakfast, consuming fast food, and drinking carbonated beverages. Later bedtime was also associated with higher perceived stress levels, particularly among students who went to bed after 2 a.m., higher rates of suicidal ideation, experiencing sadness and despair, as well as the prevalence of clinically significant anxiety disorders.</p><p><strong>Conclusion: </strong>These results suggest that middle school students who go to bed too late have higher rates of smoking and alcohol drinking, as well as unhealthy eating habits, stress, suicidal ideation, sadness, and anxiety. Therefore, it is necessary to provide educational and social institutional support to promote adequate sleep for the health of adolescents.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 2","pages":"269-281"},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10995772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信