Journal of Diabetes最新文献

{"title":"The Debate on the Dietary Guidelines for Americans (2025–2030) and Implications for China's Nutritional Policy","authors":"Junshi Chen","doi":"10.1111/1753-0407.70218","DOIUrl":"10.1111/1753-0407.70218","url":null,"abstract":"<p>On January 7, 2026, the U.S. Department of Health and Human Services and the U.S. Department of Agriculture jointly released the Dietary Guidelines for Americans (DGA, 2025–2030) [<span>1</span>]. Since its publication, the document has sparked considerable media attention and scientific debate, particularly regarding its departure from certain long-standing visual and conceptual models—the “MyPyramid” [<span>2</span>] and “MyPlate” [<span>3</span>] (Figure 1).</p><p>This commentary aims to interpret the key changes introduced in the DGA (2025–2030) and discuss their relevance and implications for China's nutrition policy and the dietary guidelines for Chinese people. The central question is: Should these American guidelines influence eating habits and public health strategies in China?</p><p>At its core, the DGA (2025–2030) does not represent a radical departure from earlier editions. The overarching objective—to prevent the increase of obesity and other non-communicable diseases (NCDs)—remains unchanged. Similarly, most foundational recommendations are consistent [<span>1</span>].</p><p>These changes have been challenged by several U.S.-based scientific bodies. The American Heart Association (AHA) and the American Society for Nutrition (ASN) have raised substantial concerns. Criticisms focus on the evidence strength for certain recommendations (particularly those mentioned above), potential industry influence, and the practical feasibility of avoiding all processed foods and sweeteners.</p><p>For example, AHA commented: “We are concerned that recommendations regarding salt seasoning and red meat consumption could inadvertently lead consumers to exceed recommended limits for sodium and saturated fats, which are primary drivers of cardiovascular disease. While the guidelines highlight whole-fat dairy, the Heart Association encourages consumption of low-fat and fat-free dairy products, which can be beneficial to heart health.” [<span>6</span>] Similarly, ASN stated: “ASN is concerned that departing from the established scientific review process undermines confidence in the DGAs and nutrition science, contributes to confusion and distrust, and obscures the opportunity for meaningful scientific discourse.” [<span>7</span>].</p><p>Prof. Cristina Palacios, a member of the Dietary Guidelines Advisory Committee (DGAC) (2022–2024), noted that “most of the Committee's recommendations were ignored in developing the latest dietary guidelines” [<span>8</span>].</p><p>To answer this, one must consider the current dietary pattern and nutritional status of the Chinese population in the context of NCD prevention, with reference to the Dietary Guidelines for Chinese People (DGCP, 2022) [<span>9</span>].</p><p>Over the past three decades (1982–2020), China's dietary patterns have shifted dramatically from traditional plant-based diets toward Westernized patterns [<span>10-14</span>]. Average dietary energy and carbohydrate intakes decreased significantly from 2","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13052287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147615599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Modulation and Central Sensitization in Painful Diabetic Peripheral Neuropathy: Updated Narrative Review and Future Directions","authors":"Di Ye,&nbsp;Timothy J. Fairchild,&nbsp;Lechi Vo,&nbsp;Peter D. Drummond","doi":"10.1111/1753-0407.70223","DOIUrl":"10.1111/1753-0407.70223","url":null,"abstract":"<p>Painful diabetic peripheral neuropathy (DPN) arises from damage to sensory neurons, manifesting in persistent pain. Progressive nerve degeneration can result in sensory loss and, in severe cases, amputation, exacerbating emotional distress and diminishing quality of life. Continuing investigation into DPN mechanisms is essential for advancing effective pain management. Our previous narrative review identified oxidative stress and central sensitization as key pathways linking hyperglycemia to nerve injury and pain. The present review provides an updated synthesis of evidence in this area. The original PubMed search term was expanded to include metabolic syndrome and pain modulation, and studies published between September 2021 and February 2026 were examined. The current findings reinforce earlier conclusions that alterations within the central nervous system and central sensitization are prominent features of painful DPN. Emerging evidence suggests that metabolic syndrome such as overweight may impair pain modulation in individuals with or without risk of diabetes. Future research should determine whether impaired pain modulation can serve as an early indicator of DPN, enabling earlier intervention. Clarifying these mechanisms may also help explain why medications that restore pain modulation show therapeutic promise for this complex chronic pain condition.</p>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147615631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subgroups of Prediabetes and the Risk of Cardiometabolic Multimorbidity in Chinese Adults: A Prospective Cohort Study.","authors":"Yan Liu, Miao He, Yu Liu, Zilin Sun, Shanhu Qiu","doi":"10.1111/1753-0407.70224","DOIUrl":"10.1111/1753-0407.70224","url":null,"abstract":"","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":"e70224"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atherogenic Index of Plasma Predicts the Onset and Progression of Cardio-Renal-Metabolic Multimorbidity: Evidence From a Nationwide Prospective Cohort Study.","authors":"Jijie Jin, Fei Wang, Shengzhang Chen, Jiaxin Shao, Binyan Chen, Xiufang Lin","doi":"10.1111/1753-0407.70227","DOIUrl":"https://doi.org/10.1111/1753-0407.70227","url":null,"abstract":"<p><strong>Background: </strong>Cardio-renal-metabolic (CRM) multimorbidity, defined by the co-occurrence of cardiovascular disease (CVD), chronic kidney disease (CKD), and type 2 diabetes (T2DM), poses a growing burden for multimorbidity management. The atherogenic index of plasma (AIP), a lipid-based marker of insulin resistance, may help predict CRM progression, but its prognostic value remains unclear.</p><p><strong>Methods: </strong>We used data from 5805 adults free of CRM at baseline in the China Health and Retirement Longitudinal Study. AIP was calculated as log₁₀[triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C)]. CRM onset was defined as incident CVD, T2DM, or CKD. Multistate models captured transitions from no disease to single, dual, and triple CRM states. Cox regression and time-dependent receiver operating characteristic (ROC) curves were used to assess associations and predictive performance.</p><p><strong>Results: </strong>AIP showed a clear dose-response relationship with CRM progression. Each 1-standard deviation (SD) increase in AIP was associated with higher risks of single (HR 1.17, 95% CI 1.13-1.22), dual (HR 1.31, 95% CI 1.21-1.41), and triple CRM (HR 1.57, 95% CI 1.27-1.94) diseases. Strong associations were observed for new-onset T2DM and stroke, but not CKD. AIP yielded the highest discrimination for triple CRM (5-year area under the curve [AUC] = 0.710). Multistate modeling showed each 1-SD increase in AIP raised the hazard of transitioning from single to dual CRM by 14% and from dual to triple by 31%.</p><p><strong>Conclusions: </strong>AIP is an independent, simple, and low-cost predictor of CRM onset and progression, with potential utility for early risk stratification and prevention.</p>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":"e70227"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13104600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing the China-SCO Cooperation Center for Metabolic Diseases to Build a Prevention and Control System for Metabolic Disorders, Advancing the Global Community of Shared Future.","authors":"Guang Ning","doi":"10.1111/1753-0407.70211","DOIUrl":"10.1111/1753-0407.70211","url":null,"abstract":"","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":"e70211"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13092369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is There Any Difference in Preferences Between Patients and Physicians? Evidence From Anti-Hyperglycemic Medications Choices for Type 2 Diabetes.","authors":"Yuliang Xiang, Liu Liu, Jing Liu, Xiong Ke, Yanfeng Ren, Shiyi Bao, Fuming Li, Shimeng Liu, Yingyao Chen","doi":"10.1111/1753-0407.70220","DOIUrl":"10.1111/1753-0407.70220","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to explore differences in preferences between Chinese patients with type 2 diabetes mellitus (T2D) and physicians when selecting anti-hyperglycemic medications.</p><p><strong>Materials and methods: </strong>We conducted a discrete choice experiment (DCE) involving 1784 patients (face-to-face surveys) and 168 physicians (online questionnaires) across eastern, central, and western China. Seven treatment attributes were assessed: HbA1c reduction, hypoglycemia risk, cardiovascular benefits, gastrointestinal adverse events, weight change, mode of administration, and monthly out-of-pocket cost. Preference heterogeneity was explored using latent class model.</p><p><strong>Results: </strong>Patients placed the greatest importance on monthly out-of-pocket cost, treatment efficacy, and hypoglycemia risk, whereas physicians prioritized hypoglycemia risk, cardiovascular benefits, and treatment efficacy. Notably, physicians tended to overestimate patients' willingness to pay for treatment benefits. Specifically, patients were willing to pay 277 CNY (39 USD) for cardiovascular benefits, whereas physicians estimated that patients would be willing to pay 864 CNY (121 USD). Latent class analysis identified substantial heterogeneity in both groups. In particular, the largest patient subgroup was strongly cost-sensitive, with preferences driven primarily by financial burden, whereas no directly corresponding physician subgroup was observed.</p><p><strong>Conclusion: </strong>Patients and physicians differ in how they prioritize diabetes medication attributes, especially regarding efficacy, cardiovascular benefit, and cost. Shared decision-making should account for these differences to support value-concordant, patient-centered diabetes care.</p>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":"e70220"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13083033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Management of Diabetic Foot Ulcers: Current Evidence and Practice.","authors":"Ji Min Kim, Seon Mee Kang, Jung Hwa Jung, Ki Chun Kim, Sanghyun Ahn, Chong Hwa Kim, Tae Sun Park, Ie Byung Park","doi":"10.1111/1753-0407.70221","DOIUrl":"https://doi.org/10.1111/1753-0407.70221","url":null,"abstract":"<p><p>Diabetic foot ulcers (DFUs) represent one of the most severe and resource-demanding complications of diabetes mellitus, significantly contributing to morbidity through infections, lower-limb amputations, reduced quality of life, and elevated healthcare expenditures. The etiology of DFUs involves a multifaceted interplay among diabetic neuropathy, peripheral arterial disease, biomechanical abnormalities, and compromised tissue repair mechanisms. Despite advancements in diabetic care, DFUs continue to pose a substantial global health burden characterized by high recurrence rates and suboptimal long-term outcomes, particularly evident in regions such as China, where recurrence rates within 1 year exceed 30% among previously healed patients. Effective DFU management requires an integrated, multidisciplinary approach beginning with early risk stratification and accurate diagnosis, followed by targeted antimicrobial therapy, meticulous wound management, appropriate mechanical offloading, and comprehensive vascular assessment and intervention. This review synthesizes contemporary evidence and current clinical guidelines concerning DFU epidemiology, diagnostic criteria, and therapeutic strategies, underscoring the critical role of interdisciplinary coordinated care to enhance clinical outcomes and mitigate associated complications.</p>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":"e70221"},"PeriodicalIF":3.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrogen-Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy","authors":"Ziyu Xu,&nbsp;Xinyu Cui,&nbsp;Houbin Chu,&nbsp;Hao Wan,&nbsp;Yunbo Xie,&nbsp;Ying Wang,&nbsp;Qingbin Ni,&nbsp;Xiaolin Ding,&nbsp;Guohua Song","doi":"10.1111/1753-0407.70209","DOIUrl":"10.1111/1753-0407.70209","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Diabetic foot ulcer (DFU) is one of the most common chronic complications of diabetes. This study developed a hydrogen-enriched hyaluronic acid (HA) dressing and aimed to explore its therapeutic effects and mechanisms in DFU treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A combination of vacuum-assisted closure (VSD) and hydrogen-rich saline was used to treat DFU patients and assess the clinical outcomes of wound repair. A rat model of DFU was established, and treatment with hydrogen-enriched HA dressing. Subsequently, the protective effects of the dressing were evaluated, including histological studies, the expression of inflammatory factors and angiogenesis markers. Western blot was used to analyze the expression levels of mitophagy-related proteins. In vitro, the role of HA and hydrogen on cell mitochondrial damage, apoptosis, migration, and markers associated with mitophagy pathways in human foreskin fibroblast-1 (HFF-1) was assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>VSD combined with hydrogen-rich saline significantly enhanced wound healing in patients, while reducing inflammation and oxidative damage. In vivo studies showed that the dressing promoted wound healing, increased collagen deposition, reduced inflammatory cytokines, and enhanced neovascularization. In vitro studies, high glucose induced cell morphological damage and oxidative stress, disrupted mitochondrial membrane potential, leading to apoptosis and attenuating cell migration. However, both HA and hydrogen significantly induced SIRT3 expression and activated the downstream FOXO3A/PINK1-PARKIN signaling pathway, promoting mitochondrial autophagy and reducing cell apoptosis. Furthermore, the SIRT3/SOD2 pathway was also activated, decreasing reactive oxygen species (ROS) production and enhancing migration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study confirmed that the hydrogen-enriched HA dressing has the potential to enhance diabetic wound repair.</p>\u0000 </section>\u0000 </div>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1753-0407.70209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147571413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Research on Childhood-Obesity Associated With Gestational Diabetes Mellitus","authors":"Wantong Chen,&nbsp;Minghui Xi,&nbsp;Shuai Li,&nbsp;Luyi Li,&nbsp;Danhuai Zhang,&nbsp;Ming Gong,&nbsp;Yueyang Zhao,&nbsp;Na Wu","doi":"10.1111/1753-0407.70212","DOIUrl":"10.1111/1753-0407.70212","url":null,"abstract":"<p>Childhood obesity has emerged as a major global public health concern. Recent reports indicate that the worldwide obesity rate among children and adolescents has climbed to 8.5%. Obesity-related conditions present serious health risks. The causes of childhood obesity are multifactorial, with growing attention from researchers on the link between maternal gestational diabetes mellitus (GDM) and an elevated risk of obesity in offspring. This association can have lasting effects throughout childhood. Consequently, understanding the causes of childhood obesity and implementing effective preventive and therapeutic measures are crucial for managing and mitigating the condition and its associated health complications. This study aims to thoroughly explore the relationship between maternal GDM and the heightened risk of childhood obesity, examining developmental stages, underlying pathophysiological mechanisms, and contributing factors. By developing and applying targeted management strategies during a child's growth and development, the objective is to effectively curb and improve obesity outcomes among children born to mothers with GDM.</p>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1753-0407.70212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147502620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroinflammation-Associated Optic Structural–Functional Degeneration in Early Diabetic Optic Neuropathy","authors":"Jingyuan Zhu,&nbsp;Jinyuan Wang,&nbsp;Haihan Zhang,&nbsp;Mingyang Wang","doi":"10.1111/1753-0407.70198","DOIUrl":"10.1111/1753-0407.70198","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Diabetic optic neuropathy (DON) is characterized by optic nerve degenerative changes, which may progress to optic atrophy and even blindness. Although DON is relatively common, its early diagnosis remains challenging. This study employed a noninvasive in vivo imaging combined histopathological assessment system to investigate changes in optic structural–functional degeneration in DON models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Animals were divided into experimental group (8 db/db mice) and control group (8 db/m mice). Blood glucose, body weight, intraocular pressure, peripapillary retinal nerve fiber layer (RNFL), total retinal thickness (TRT), and visual behavior were at 2, 3, 4, 5 and 8 months old. Furthermore, histopathological and molecular validations were performed on the peripapillary retinal tissue.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Across the 6-month follow-ups, db/db mice remained hyperglycemic and obese. Compared with the control group, db/db mice showed significant thinning of the peripapillary RNFL and TRT, and pyroptosis of retinal gangolion cells at 3 months old, suggesting optic nerve degeneration. Meanwhile, decreased visual acuity and increased contrast sensitivity thresholds confirmed the establishment of an early DON model. Thinning of the TRT at 8 months old was found to be linearly correlated with decreased visual acuity, but not with contrast thresholds in the DON group. No significant differences of intraocular pressure were found between groups at any time point.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Db/db mice provide a reliable model for early DON study. Retinal structural impairment was closely associated with visual dysfunction, underscoring the link between neurodegeneration and functional loss. These findings may facilitate early diagnosis and treatment of DON.</p>\u0000 </section>\u0000 </div>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"18 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1753-0407.70198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}