{"title":"Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients With Type 2 Diabetes: A National Prospective Cohort Study: A Commentary","authors":"Nimra Khan, Rida-e-Zehra, Nandni Dileep","doi":"10.1111/1753-0407.70146","DOIUrl":null,"url":null,"abstract":"<p>This commentary discusses the study “Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients with Type 2 Diabetes: A National Prospective Cohort Study” by Xi et al. The study provides a perceptive investigation of how metabolic characteristics and genetic variables interact to affect body mass index (BMI) in people with T2D. It has some limitations, including reliance on self-reported sleep data and lack of in-depth sleep quality assessment. We highlight the importance of objective sleep data, detailed assessments of sleep quality, and advanced polygenic risk models in future research to better understand these relationships and inform precision diabetes care.</p>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"17 8","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1753-0407.70146","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Diabetes","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/1753-0407.70146","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
Abstract
This commentary discusses the study “Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients with Type 2 Diabetes: A National Prospective Cohort Study” by Xi et al. The study provides a perceptive investigation of how metabolic characteristics and genetic variables interact to affect body mass index (BMI) in people with T2D. It has some limitations, including reliance on self-reported sleep data and lack of in-depth sleep quality assessment. We highlight the importance of objective sleep data, detailed assessments of sleep quality, and advanced polygenic risk models in future research to better understand these relationships and inform precision diabetes care.
期刊介绍:
Journal of Diabetes (JDB) devotes itself to diabetes research, therapeutics, and education. It aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. The Editorial team is international with a unique mix of Asian and Western participation.
The Editors welcome submissions in form of original research articles, images, novel case reports and correspondence, and will solicit reviews, point-counterpoint, commentaries, editorials, news highlights, and educational content.