Pingzhi Li, Gijs W A Simons, Tianyu Zhang, Philip P J Schrinner, Sohrab Kamyar, Ronald Dekker, Diana C Leitao, Reinoud Lavrijsen, Yuqing Jiao, Bert Koopmans
{"title":"Demonstration of on-chip all-optical switching of magnetization in integrated photonics.","authors":"Pingzhi Li, Gijs W A Simons, Tianyu Zhang, Philip P J Schrinner, Sohrab Kamyar, Ronald Dekker, Diana C Leitao, Reinoud Lavrijsen, Yuqing Jiao, Bert Koopmans","doi":"10.1038/s41565-026-02281-3","DOIUrl":"https://doi.org/10.1038/s41565-026-02281-3","url":null,"abstract":"<p><p>Ultrafast all-optical switching of magnetization holds great promise for next-generation spintronic memory and hybrid spintronic-photonic systems. However, most implementations so far have relied on bulky free-space optical setups, limiting scalability and practical integration. Here, as a critical step towards integrated applications, we demonstrate the single-pulse all-optical switching of magnetization within a silicon nitride photonic integrated circuit. Using trains of femtosecond laser pulses guided through on-chip waveguides, we achieve deterministic toggle switching in a submicrometre out-of-plane Co/Gd Hall cross patterned directly atop the photonic waveguide. Electrical read-out via the anomalous Hall effect reveals a switching contrast of up to 90% for 500-nm-wide devices. In larger Hall crosses, the contrast decreases and switching becomes stochastic, consistent with spatially non-uniform optical absorption as confirmed by finite-element simulations. This behaviour is hypothetically attributed to domain-wall relaxation and thermally assisted (de)pinning processes within partially switched regions. Our results highlight the critical role of device scaling in achieving robust on-chip all-optical switching of magnetization and establish a foundation for ultrafast, energy-efficient and fully integrated spintronic-photonic platforms.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":" ","pages":""},"PeriodicalIF":37.5,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148970292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph D. Minnella, Mathieu Ouellet, Amelia R. Klein, Lee C. Bassett
{"title":"Single-gate, multipartite entanglement on a room-temperature quantum register","authors":"Joseph D. Minnella, Mathieu Ouellet, Amelia R. Klein, Lee C. Bassett","doi":"10.1038/s41565-026-02254-6","DOIUrl":"10.1038/s41565-026-02254-6","url":null,"abstract":"Multipartite entanglement is an essential aspect of quantum systems, needed to execute quantum algorithms, implement error correction and achieve quantum-enhanced sensing. In solid-state quantum registers such as nitrogen-vacancy centres in diamond, entangled states are typically created using sequential, pairwise gates between the central electron and individual nuclear qubits. This sequential approach is slow and suffers from crosstalk errors. Here we demonstrate a parallelized multi-qubit entangling gate to generate a four-qubit Greenberger–Horne–Zeilinger state using a room-temperature nitrogen-vacancy centre in only 14.8 μs—ten times faster than that using sequences of two-qubit gates and close to the fundamental limit set by the hyperfine coupling frequencies. Parallel three-qubit gates are also realized with all-nuclear-qubit subsets. The entangled states are verified by measuring multiple quantum coherences. The four-qubit parallel gate has a fidelity of 0.92(4), whereas the sequential four-qubit gate fidelity is only 0.69(3). The approach is generalizable to other solid-state platforms, and it lays the foundation for scalable generation and control of entanglement in practical devices. This work demonstrates a parallelized four-qubit entangling gate on a room-temperature spin register, and it operates ten times faster than sequences of two-qubit gates with reduced errors.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"21 10","pages":"1383-1389"},"PeriodicalIF":37.5,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-026-02254-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148970282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yitong Chen, Guoqiang Yang, Tao Yan, Chunyang Tang, Jiamin Wu, Qionghai Dai
{"title":"How nanophotonics can drive optical computing toward practical applications.","authors":"Yitong Chen, Guoqiang Yang, Tao Yan, Chunyang Tang, Jiamin Wu, Qionghai Dai","doi":"10.1038/s41565-026-02264-4","DOIUrl":"https://doi.org/10.1038/s41565-026-02264-4","url":null,"abstract":"<p><p>The rapid advancement of artificial intelligence (AI) imposes unprecedented speed and energy requirements on large-scale computation. Owing to its intrinsic high bandwidth, massive parallelism capacity and low energy consumption, optical computing is widely regarded as one of the most promising technologies to address AI computation demands. Here we offer a synthesis of photonic platforms that have already shown programmability, high integration density and stability, and that can support large-scale AI models, edge computing, and logic and scientific computing. We summarize the requirements that optical computing imposes on nanomaterials properties, architecture design, nanofabrication and large-scale integration. Finally, we analyse commercial systems and provide a perspective on how nanotechnology-informed solutions can improve performance in terms of computing speed, scalability and complexity in optical computing.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":" ","pages":""},"PeriodicalIF":37.5,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dengpan Liang, Yalin Qi, Hesong Han, Negar Ahmadian, Kewa Gao, Kaycee Sapasap, Yuxi Zhang, Silin Guo, Atip Lawanprasert, Sopida Pimcharoen, Sheng Zhao, Milan T. Del Buono, He Xia, Zoe O. Enders, Benjamin W. Burgstone, Antonino Calio, Neel Dankar, Bingwei Lu, Lei S. Qi, Aijun Wang, Niren Murthy
{"title":"Charge-switching ionizable lipids lower the toxicity of lipid nanoparticles","authors":"Dengpan Liang, Yalin Qi, Hesong Han, Negar Ahmadian, Kewa Gao, Kaycee Sapasap, Yuxi Zhang, Silin Guo, Atip Lawanprasert, Sopida Pimcharoen, Sheng Zhao, Milan T. Del Buono, He Xia, Zoe O. Enders, Benjamin W. Burgstone, Antonino Calio, Neel Dankar, Bingwei Lu, Lei S. Qi, Aijun Wang, Niren Murthy","doi":"10.1038/s41565-026-02262-6","DOIUrl":"10.1038/s41565-026-02262-6","url":null,"abstract":"Lipid nanoparticles (LNPs) have great potential as nucleic acid delivery vehicles; however, they trigger the production of inflammatory cytokines, which limits their medical applications. Developing non-inflammatory LNPs is challenging because the LNP’s ionizable lipid and the process of endosomal disruption are the major sources of LNP toxicity but are also essential for delivering nucleic acids. Here we demonstrate that ionizable lipids containing a carboxylic acid and an amine (termed S-lipid) switch their charged state between the pHs of 7.4 and 4.0, allowing them to generate LNPs (termed switchable nanoparticles) that efficiently encapsulate nucleic acid and trigger endosomal release without activation of the TLR4, complement, galectin-8 and platelet activating factor signalling pathways. Finally, we demonstrate that switchable nanoparticles are better at treating lipopolysaccharide-induced acute lung injury than traditional LNPs because they do not exacerbate pre-existing inflammation. Collectively, these results demonstrate that negatively charged ionizable lipids can mitigate the toxicity of LNPs. Charge-switching S-lipids generate S-lipid nanoparticles that are neutral or negative at physiological pH but become cationic in acidic endosomes, enabling nucleic acid delivery with reduced inflammation compared with conventional LNPs.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"21 10","pages":"1479-1488"},"PeriodicalIF":37.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-026-02262-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shunfa Liu, Jiantao Ma, Hanqing Liu, Yangpeng Wang, Xueshi Li, Haiqiao Ni, Zhichuan Niu, Kai Zou, Yun Meng, Xiaolong Hu, Xuehua Wang, Jin Liu
{"title":"Structured light-matter interaction in semiconductor cavity quantum electrodynamics.","authors":"Shunfa Liu, Jiantao Ma, Hanqing Liu, Yangpeng Wang, Xueshi Li, Haiqiao Ni, Zhichuan Niu, Kai Zou, Yun Meng, Xiaolong Hu, Xuehua Wang, Jin Liu","doi":"10.1038/s41565-026-02275-1","DOIUrl":"https://doi.org/10.1038/s41565-026-02275-1","url":null,"abstract":"<p><p>A cavity quantum electrodynamics system consisting of a confined single photon and a single quantum emitter serves as a fundamental block for quantum optics and photonic quantum technologies. The canonical optical mode used in the conventional cavity quantum electrodynamics features a uniform polarization distribution, leading to the scalar light-matter interaction in most existing experiments. Despite the rapid progress in the generation of structured light with spatially varied polarizations, the structured light-matter interaction, especially at the single-quanta level, is highly intriguing yet largely unexplored. Here we present the structured light-matter interaction at the single-photon level in a semiconductor cavity quantum electrodynamics system. Four distinct structured cavity modes that are spectrally close to each other are constructed in a micropillar cavity. By spatially locating a single epitaxial quantum dot (InAs quantum dot) at the periphery of a semiconductor micropillar cavity and spectrally tuning the quantum dot emission wavelength into the resonances of the structured cavity modes, cavity-enhanced single-photon emissions with spin-locked chiral orbital angular momentum and engineerable spin-orbit entanglements are achieved within a single wavelength-scale device. Our work opens different ways of exploring structured quantum light-matter interactions in chiral quantum optics and high-dimensional photonic quantum technology.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":" ","pages":""},"PeriodicalIF":37.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Switchable single-atom catalysts for highly selective C–C coupling in direct methane oxidation","authors":"Xiao Han, Peixin Cui, Geng Wu, Jinyan Cai, Chao Wang, Fanfei Sun, Panzhe Qiao, Xiaocheng Liu, Jiahao Zhuang, Huan Liu, Fabing Su, Gongming Wang, Wensheng Yan, Zeming Qi, Yue Lin, Xun Hong, Yadong Li","doi":"10.1038/s41565-026-02271-5","DOIUrl":"https://doi.org/10.1038/s41565-026-02271-5","url":null,"abstract":"Direct selective conversion of methane into high value-added chemical products has long attracted attention in both industry and academia. The production of C2 oxygenates is especially challenging owing to the requirement for both C–H activation and C–C coupling. Here we report a boron nanosheet-supported Cu single atom with Cu–B4 sites (Cu-SAs/B), which can effectively catalyse the conversion of methane to acetic acid with 97% selectivity and a high activity of 221.3 mmol gCu−1 h−1 without the addition of CO. In situ X-ray absorption fine structure analysis reveals that Cu single atoms undergo reversible ‘switching’ to Cu4 clusters under CH4 oxidation conditions, enabling efficient C–H activation and C–C coupling. The switching behaviour is triggered by the presence of H2O2, and the coupling occurs between CH3* and CHO* intermediates formed on Cu single atoms and Cu clusters, respectively, as confirmed by in situ spectroscopic techniques. These findings provide a proof of concept for designing highly effective methane oxidation catalysts based on switchable nanocatalysts.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"11 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}