Qijie Lin, Congqi Li, Haigen Xiong, Meng Zhang, Jiawei Qiao, Jingpeng Wu, Lei Yang, Song Wang, Hao Chen, Yanan Wei, Di Zheng, Guanghao Lu, Xiaotao Hao, Donghong Yu, Yunhao Cai, Antonio Facchetti, Hui Huang
{"title":"Event-driven retinomorphic photodiode with bio-plausible temporal dynamics","authors":"Qijie Lin, Congqi Li, Haigen Xiong, Meng Zhang, Jiawei Qiao, Jingpeng Wu, Lei Yang, Song Wang, Hao Chen, Yanan Wei, Di Zheng, Guanghao Lu, Xiaotao Hao, Donghong Yu, Yunhao Cai, Antonio Facchetti, Hui Huang","doi":"10.1038/s41565-025-01973-6","DOIUrl":"https://doi.org/10.1038/s41565-025-01973-6","url":null,"abstract":"<p>Machine vision is indispensable in Industry 4.0 and autonomous driving, enabling the perception and reaction necessary to navigate dynamic environments. Current machine vision sensors, including frame-based and event-based types, often fall short due to their limited temporal dynamics compared with the human retina, hindering their overall performance and adaptability. In this work, we present an event-driven retinomorphic photodiode (RPD) that mimics the retina’s layered structure and signal pathway. The RPD achieves this by vertically integrating an organic donor–acceptor heterojunction, an ion reservoir with a porous web-like morphology, and a Schottky junction into a single diode through controlled layer-by-layer fabrication and precise nanostructure modulation. Each component replicates a key retinal process, and their spontaneous interaction results in environment-adaptive dynamics. This design yields a dynamic range exceeding 200 dB, substantially reduces noise and data redundancy, and allows for high-density integration. We demonstrate that these improvements enable high-quality machine vision, even under extreme lighting conditions. Our work demonstrates a bottom-up approach to retinomorphic sensors, propelling the development of robust and responsive machine vision systems adaptable to complex and dynamic lighting environments.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"163 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144684940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinxin Jing, Nicolas Kroneberg, Andreas Peil, Benjamin Renz, Longjiang Ding, Tobias Heil, Katharina Hipp, Peter A. van Aken, Hao Yan, Na Liu
{"title":"DNA moiré superlattices","authors":"Xinxin Jing, Nicolas Kroneberg, Andreas Peil, Benjamin Renz, Longjiang Ding, Tobias Heil, Katharina Hipp, Peter A. van Aken, Hao Yan, Na Liu","doi":"10.1038/s41565-025-01976-3","DOIUrl":"https://doi.org/10.1038/s41565-025-01976-3","url":null,"abstract":"<p>Moiré superlattices have been extensively designed and implemented in atomic-scale van der Waals systems and submicrometre-scale photonic systems. However, bridging the structural gap between these scales has remained a substantial challenge. Here we demonstrate engineered DNA moiré superlattices with sublattice constants as small as ~2 nm and moiré periodicities spanning tens of nanometres. Using twisted DNA origami nanoseeds, we precisely control the layered registry of 2D microscale single-stranded tile DNA sublattices, achieving seed-defined twist angles with deviations below 2°, along with customizable interlayer spacing, stacking sequences and sublattice symmetries. The modularity of nucleation sites on the seeds enables synthetic control over the nucleation and growth pathways, resulting in a high bilayer fraction of 90%. Notably, we demonstrate a gradient moiré superlattice with a gradual variation in moiré periodicity, highlighting the potential of DNA nanotechnology to construct entirely new artificial structures and materials from the bottom up.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"14 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144645479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edoardo Lopriore, Fedele Tagarelli, Jamie M. Fitzgerald, Juan Francisco Gonzalez Marin, Kenji Watanabe, Takashi Taniguchi, Ermin Malic, Andras Kis
{"title":"Enhancing interlayer exciton dynamics by coupling with monolithic cavities via the field-induced Stark effect","authors":"Edoardo Lopriore, Fedele Tagarelli, Jamie M. Fitzgerald, Juan Francisco Gonzalez Marin, Kenji Watanabe, Takashi Taniguchi, Ermin Malic, Andras Kis","doi":"10.1038/s41565-025-01969-2","DOIUrl":"https://doi.org/10.1038/s41565-025-01969-2","url":null,"abstract":"<p>Optical microcavities provide a powerful and versatile framework for manipulating the dynamics of photonic emission from optically active materials through light recirculation. Spatially indirect interlayer excitons (IXs) exhibit broad tunability of their emission energy via the quantum-confined Stark effect. However, the electrical tunability of IXs has not been exploited in cavity-coupled systems until now. Here we modulate the detuning between the cavity resonance and the IX emission in a monolithic Fabry–Perot cavity using an applied vertical electric field. We reveal a simultaneous enhancement of both the emission intensity and lifetime of weakly coupled IXs when in resonance with the optical cavity owing to strong Purcell inhibition and cavity transparency effects. We further investigate the tunable momentum dispersion of coupled IXs through back-focal-plane imaging and explain our results by the cavity coupling of IX transition dipoles as supported by theoretical modelling. Our work demonstrates an integration effort enabling the versatile tuning of highly interacting IXs within monolithic cavities, revealing the attractiveness of electrically tunable IX cavity coupling for both fundamental studies towards exciton condensate manipulation and future integration of excitonic devices.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"29 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144645478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crumpled graphene oxide membranes enable rapid and selective hydrogen separation","authors":"","doi":"10.1038/s41565-025-01978-1","DOIUrl":"https://doi.org/10.1038/s41565-025-01978-1","url":null,"abstract":"It is difficult to achieve a balance between maximizing permeation and maintaining high selectivity in gas separation. Mechanochemically crumpled graphene oxide membranes break this trade-off, offering high H2 permeability and H2/CO2 selectivity under industrially relevant conditions. These robust membranes have the potential to be scaled up for energy-efficient decarbonization technologies.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"24 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144622415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pengxiang Zhang, Qian Wang, Yixin Zhang, Mo Lin, Xin Zhou, Ashish David, Andrey Ustyuzhanin, Musen Chen, Mikhail I. Katsnelson, Maxim Trubyanov, Kostya S. Novoselov, Daria V. Andreeva
{"title":"Strain-induced crumpling of graphene oxide lamellas to achieve fast and selective transport of H2 and CO2","authors":"Pengxiang Zhang, Qian Wang, Yixin Zhang, Mo Lin, Xin Zhou, Ashish David, Andrey Ustyuzhanin, Musen Chen, Mikhail I. Katsnelson, Maxim Trubyanov, Kostya S. Novoselov, Daria V. Andreeva","doi":"10.1038/s41565-025-01971-8","DOIUrl":"https://doi.org/10.1038/s41565-025-01971-8","url":null,"abstract":"<p>Graphene oxide (GO) membranes offer high selectivity and energy-efficient gas separation. However, their dense, layered structure and tortuous diffusion paths limit permeability, posing a barrier to industrial use. Here we present a method to enhance selectivity and permeability, maintaining the structural stability of such membranes. With an industrially friendly manufacturing method, we produce crumpled GO membranes with gas diffusion pathways controlled by a multidomain structure. These membranes achieve H<sub>2</sub> permeability of approximately 2.1 × 10<sup>4</sup> barrer, significantly surpassing the permeability of flat lamellar GO membranes, which is below 100 barrer. Its H<sub>2</sub>/CO<sub>2</sub> selectivity of 91 outperforms current membrane technologies. In addition, the crumpled membranes demonstrate stability under harsh conditions (−20 °C, 96% relative humidity), a critical requirement for practical applications. This work addresses the long-standing permeability–selectivity trade-off and establishes a robust, scalable platform for integrating two-dimensional materials into membrane technology for real-world applications.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"14 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144622424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dong Wang, Lei Ji, You Li, Meng Xu, Hao Wang, Sergio Brovelli, Zeng-Ying Qiao, Jiatao Zhang, Yadong Li
{"title":"Iron–silver-modified quantum dots act as efficient catalysts in anti-cancer multitherapy through controlled, ultrasound-induced oxidation","authors":"Dong Wang, Lei Ji, You Li, Meng Xu, Hao Wang, Sergio Brovelli, Zeng-Ying Qiao, Jiatao Zhang, Yadong Li","doi":"10.1038/s41565-025-01943-y","DOIUrl":"https://doi.org/10.1038/s41565-025-01943-y","url":null,"abstract":"<p>Chemodynamic therapy and sonodynamic therapy are two promising tumour therapeutic strategies. However, lack of highly effective sonosensitizers and control over chemodynamic therapy limit their application. Here we synthesize silver-doped zinc selenide quantum dots with atomically dispersed superficial Fe and show that they act as efficient sonosensitizers, catalysers and immunoreagents. Surface modification with an in situ self-assembly peptide drives accumulation in tumours. Superficial Fe<sup>III</sup> remains stable and converts to Fe<sup>II</sup> only under ultrasonic processing, reverting to Fe<sup>III</sup> upon ultrasound cessation. Under ultrasound stimulation, superficial Fe undergoes valence change with concomitant amelioration of the hypoxic tumour microenvironment and production of sonodynamic therapy-beneficial hydroxyl radicals. Furthermore, silver doping suppressed nonradiative recombination of excitons, leading to improved production of singlet oxygen. Meanwhile, selenium promotes robust systemic immune responses for the inhibition of tumour metastases. This nano-platform allows control of valence switching of atomically dispersed catalysts, representing an effective tool for chemodynamic/sonodynamic/immunotherapy.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"1 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144594140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observation of chiral emission enabled by collective guided resonances","authors":"Ye Chen, Mingjin Wang, Jiahao Si, Zixuan Zhang, Xuefan Yin, Jingxuan Chen, Nianyuan Lv, Chenyan Tang, Wanhua Zheng, Yuri Kivshar, Chao Peng","doi":"10.1038/s41565-025-01964-7","DOIUrl":"https://doi.org/10.1038/s41565-025-01964-7","url":null,"abstract":"<p>A simple yet insightful question is whether it is possible to arrange optical resonances in such a way that their collective response differs from that of the individual constituents. Here, inspired by the collective oscillation of spatially localized modes and Fourier duality between real and momentum spaces, we demonstrate a chiral emission of collective guided modes by leveraging the omnidirectional hybridization of individual guided resonances within a photonic crystal slab. Specifically, we encircle a uniform photonic crystal with isotropic boundaries and hybridize discrete bulk guided resonances into a series of collective modes owing to the scatterings of the boundaries. This results in a chiral spiral vortex emission in real space. By using asymmetric pumping to lift the chiral symmetry, we then achieve stable single-mode lasing oscillation of the spiral collective mode and confirm the nature of vortex emission through polarization-resolved imaging and self-interference patterns, thus demonstrating a vivid example of collective oscillations in the momentum space.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"27 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunxuan Li, Siong Chen Meng, Yesheng Wang, Casey M. Platnich, Max K. Earle, Elli Mylona, Plamena Naydenova, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser
{"title":"Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches","authors":"Yunxuan Li, Siong Chen Meng, Yesheng Wang, Casey M. Platnich, Max K. Earle, Elli Mylona, Plamena Naydenova, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser","doi":"10.1038/s41565-025-01965-6","DOIUrl":"https://doi.org/10.1038/s41565-025-01965-6","url":null,"abstract":"<p>RNA mutations and modifications have been implicated in a wide range of pathophysiologies. However, current RNA detection methods are hindered by data complexity and error-prone protocols, restricting their widespread use. Here we present a solid-state nanopore-based approach, RNA single-nucleotide characterization and analysis nanolatch (RNA-SCAN) system, which simplifies the detection of nucleotide mutations and modifications in RNA with high resolution. Using phage RNA as a template, we tested multiple sequences and chemical modifications on nanolatches, allowing the detection of mismatches caused by nucleotide mutations through significant changes in positive event ratios using single-molecule nanopore measurements. This approach is also sensitive to modifications that either strengthen or weaken the interaction between the target RNA sequence and the nanolatch. As a proof-of-concept, we demonstrate successful discrimination of <i>Escherichia coli</i> and <i>Salmonella</i> spp. from total RNA based on nucleotide variations in their 16S rRNA, as well as quantification of different <i>Salmonella</i> spp. and detection of m<sup>5</sup>C1407 modification on <i>E. coli</i> 16S rRNA. The RNA-SCAN approach demonstrates the feasibility of combining RNA/DNA hybrid nanotechnology with nanopore sensing and diagnosing RNA-related health conditions.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"46 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"States of shear wander","authors":"Conor J. McCluskey, John Marty Gregg","doi":"10.1038/s41565-025-01960-x","DOIUrl":"https://doi.org/10.1038/s41565-025-01960-x","url":null,"abstract":"Shear stress, induced by the tip of an atomic force microscope, stabilizes ferroelastic domain variants and thereby reversibly controls magnetic microstructure and magnetotransport behaviour in thin-film oxides.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"1 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}