Nature nanotechnology最新文献

{"title":"Quantum dots are beginning to lase in the blue","authors":"Patanjali Kambhampati","doi":"10.1038/s41565-024-01828-6","DOIUrl":"https://doi.org/10.1038/s41565-024-01828-6","url":null,"abstract":"Lasing from quantum dots has been demonstrated in the previously inaccessible blue spectral region by virtue of carefully engineered Zn-based materials.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"71 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superionic conducting vacancy-rich β-Li3N electrolyte for stable cycling of all-solid-state lithium metal batteries","authors":"Weihan Li, Minsi Li, Shuo Wang, Po-Hsiu Chien, Jing Luo, Jiamin Fu, Xiaoting Lin, Graham King, Renfei Feng, Jian Wang, Jigang Zhou, Ruying Li, Jue Liu, Yifei Mo, Tsun-Kong Sham, Xueliang Sun","doi":"10.1038/s41565-024-01813-z","DOIUrl":"https://doi.org/10.1038/s41565-024-01813-z","url":null,"abstract":"<p>The advancement of all-solid-state lithium metal batteries requires breakthroughs in solid-state electrolytes (SSEs) for the suppression of lithium dendrite growth at high current densities and high capacities (&gt;3 mAh cm⁻²) and innovation of SSEs in terms of crystal structure, ionic conductivity and rigidness. Here we report a superionic conducting, highly lithium-compatible and air-stable vacancy-rich β-Li₃N SSE. This vacancy-rich β-Li₃N SSE shows a high ionic conductivity of 2.14 × 10⁻³ S cm⁻¹ at 25 °C and surpasses almost all the reported nitride-based SSEs. A Li- and N-vacancy-mediated fast lithium-ion migration mechanism is unravelled regarding vacancy-triggered reduced activation energy and increased mobile lithium-ion population. All-solid-state lithium symmetric cells using vacancy-rich β-Li₃N achieve breakthroughs in high critical current densities up to 45 mA cm⁻² and high capacities up to 7.5 mAh cm⁻², and ultra-stable lithium stripping and plating processes over 2,000 cycles. The high lithium compatibility mechanism of vacancy-rich β-Li₃N is unveiled as intrinsic stability to lithium metal. In addition, β-Li₃N possesses excellent air stability through the formation of protection surfaces. All-solid-state lithium metal batteries using the vacancy-rich β-Li₃N as SSE interlayers and lithium cobalt oxide (LCO) and Ni-rich LiNi_0.83Co_0.11Mn_0.06O₂ (NCM83) cathodes exhibit excellent battery performance. Extremely stable cycling performance is demonstrated with high capacity retentions of 82.05% with 95.2 mAh g⁻¹ over 5,000 cycles at 1.0 C for LCO and 92.5% with 153.6 mAh g⁻¹ over 3,500 cycles at 1.0 C for NCM83. Utilizing the vacancy-rich β-Li₃N SSE and NCM83 cathodes, the all-solid-state lithium metal batteries successfully accomplished mild rapid charge and discharge rates up to 5.0 C, retaining 60.47% of the capacity. Notably, these batteries exhibited a high areal capacity, registering approximately 5.0 mAh cm⁻² for the compact pellet-type cells and around 2.2 mAh cm⁻² for the all-solid-state lithium metal pouch cells.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"19 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142696538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atomically intimate assembly of dual metal–oxide interfaces for tandem conversion of syngas to ethanol","authors":"Shang Li, Li Feng, Hengwei Wang, Yue Lin, Zhihu Sun, Lulu Xu, Yuxing Xu, Xinyu Liu, Wei-Xue Li, Shiqiang Wei, Jin-Xun Liu, Junling Lu","doi":"10.1038/s41565-024-01824-w","DOIUrl":"https://doi.org/10.1038/s41565-024-01824-w","url":null,"abstract":"<p>Selective conversion of syngas to value-added higher alcohols (containing two or more carbon atoms), particularly to a specific alcohol, is of great interest but remains challenging. Here we show that atomically intimate assembly of FeO_<i>x</i>-Rh-ZrO₂ dual interfaces by selectively architecting highly dispersed FeO_<i>x</i> on ultrafine raft-like Rh clusters supported on tetragonal zirconia enables highly efficient tandem conversion of syngas to ethanol. The ethanol selectivity in oxygenates reached ~90% at CO conversion up to 51%, along with a markedly high space-time yield of ethanol of 668.2 mg g_cat⁻¹ h⁻¹. In situ spectroscopic characterization and theoretical calculations reveal that Rh-ZrO₂ interface promotes dissociative CO activation into CH_<i>x</i> through a formate pathway, while the adjacent Rh-FeO_<i>x</i> interface accelerates subsequent C–C coupling via nondissociative CO insertion. Consequently, these dual interfaces in atomic-scale proximity with complementary functionalities synergistically boost the exclusive formation of ethanol with exceptional productivity in a tandem manner.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"80 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142696542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cascade X-ray energy converting approach toward radio-afterglow cancer theranostics","authors":"Cheng Xu, Xue Qin, Xin Wei, Jie Yu, Youjia Zhang, Yan Zhang, Dan Ding, Jibin Song, Kanyi Pu","doi":"10.1038/s41565-024-01809-9","DOIUrl":"https://doi.org/10.1038/s41565-024-01809-9","url":null,"abstract":"<p>Leveraging X-rays to initiate prolonged luminescence (radio-afterglow) and stimulate radiodynamic ¹O₂ production from optical agents provides opportunities for diagnosis and therapy at tissue depths inaccessible to light. However, X-ray-responsive organic luminescent materials are rare due to their intrinsic low X-ray conversion efficiency. Here we report a cascade X-ray energy converting approach to develop organic radio-afterglow nanoprobes (RANPs) for cancer theranostics. RANPs comprise a radiowave absorber that down-converts X-ray energy to emit radioluminescence, which is transferred to a radiosensitizer to produce singlet oxygen (¹O₂). ¹O₂ then reacts with a radio-afterglow substrate to generate an active intermediate that simultaneously decomposes to emit radio-afterglow. Through finetuning such a cascade, intraparticle radioluminescence energy transfer and the ¹O₂ transfer process, RANPs possess tunable wavelengths and long half-lives, and generate radio-afterglow and ¹O₂ at tissue depths of up to 15 cm. Moreover, we developed a biomarker-activatable nanoprobe (tRANP) that produces a tumour-specific radio-afterglow signal, leading to ultrasensitive detection and the possibility of surgical removal of diminutive tumours (1 mm³) under an X-ray dosage 20 times lower than inorganic materials. The efficient radiodynamic ¹O₂ generation of tRANP permits complete tumour eradication at an X-ray dosage lower than clinical radiotherapy and a drug dosage one to two orders of magnitude lower than most existing inorganic agents, leading to prolonged survival rates with minimized radiation-related adverse effects. Thus, our work reveals a generic approach to address the lack of organic radiotheranostic materials and provides molecular design towards precision cancer radiotherapy.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"17 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142637119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organic radio-afterglow nanoprobes for cancer theranostics","authors":"","doi":"10.1038/s41565-024-01810-2","DOIUrl":"https://doi.org/10.1038/s41565-024-01810-2","url":null,"abstract":"Leveraging X-rays to induce prolonged luminescence (radio-afterglow) and radiodynamic effects from typically inorganic optical agents enables diagnosis and therapy at light-inaccessible tissue depths. Now, a cascade X-ray energy conversion approach is developed to increase the intrinsically low X-ray conversion efficiency of organic molecules for the construction of radio-afterglow nanoprobes for cancer theranostics.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"98 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142637118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Layer-dependent evolution of electronic structures and correlations in rhombohedral multilayer graphene","authors":"Yang Zhang, Yue-Ying Zhou, Shihao Zhang, Hao Cai, Ling-Hui Tong, Wei-Yu Liao, Ruo-Jue Zou, Si-Min Xue, Yuan Tian, Tongtong Chen, Qiwei Tian, Chen Zhang, Yiliu Wang, Xuming Zou, Xingqiang Liu, Yuanyuan Hu, Ya-Ning Ren, Li Zhang, Lijie Zhang, Wen-Xiao Wang, Lin He, Lei Liao, Zhihui Qin, Long-Jing Yin","doi":"10.1038/s41565-024-01822-y","DOIUrl":"https://doi.org/10.1038/s41565-024-01822-y","url":null,"abstract":"<p>The recent discovery of superconductivity and magnetism in trilayer rhombohedral graphene (RG) establishes an ideal, untwisted platform to study strong correlation electronic phenomena. However, the correlated effects in multilayer RG have received limited attention, and, particularly, the evolution of the correlations with increasing layer number remains an unresolved question. Here we show the observation of layer-dependent electronic structures and correlations—under surprising liquid nitrogen temperature—in RG multilayers from 3 to 9 layers by using scanning tunnelling microscopy and spectroscopy. We explicitly determine layer-enhanced low-energy flat bands and interlayer coupling strengths. The former directly demonstrates the further flattening of low-energy bands in thicker RG, and the latter indicates the presence of varying interlayer interactions in RG multilayers. Moreover, we find significant splittings of the flat bands, ranging from ~50 meV to 80 meV, at 77 K when they are partially filled, indicating the emergence of interaction-induced strongly correlated states. Particularly, the strength of the correlated states is notably enhanced in thicker RG and reaches its maximum in the six-layer, validating directly theoretical predictions and establishing abundant new candidates for strongly correlated systems. Our results provide valuable insights into the layer dependence of the electronic properties in RG and demonstrate it as a suitable system for investigating robust and highly accessible correlated phases.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"72 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142601594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full on-device manipulation of olefin metathesis for precise manufacturing","authors":"Yilin Guo, Chen Yang, Lei Zhang, Yujie Hu, Jie Hao, Chuancheng Jia, Yang Yang, Yan Xu, Xingxing Li, Fanyang Mo, Yanwei Li, Kendall N. Houk, Xuefeng Guo","doi":"10.1038/s41565-024-01814-y","DOIUrl":"https://doi.org/10.1038/s41565-024-01814-y","url":null,"abstract":"<p>Olefin metathesis, as a powerful metal-catalysed carbon–carbon bond-forming method, has achieved considerable progress in recent years. However, the complexity originating from multicomponent interactions has long impeded a complete mechanistic understanding of olefin metathesis, which hampers further optimization of the reaction. Here, we clarify both productive and hidden degenerate pathways of ring-closing metathesis by focusing on one individual catalyst, using a sensitive single-molecule electrical detection platform. In addition to visualizing the full pathway, we found that the conventionally unwanted degenerate pathways have an unexpected constructive coupling effect on the productive pathway, and both types of pathway can be regulated by an external electric field. We then pushed forward this ability to ring-opening metathesis polymerization involving more interactive components. With single-monomer-insertion-event resolution, precise on-device synthesis of a single polymer was achieved by online manipulation of monomer insertion dynamics, intramolecular chain transfer, stereoregularity, degree of polymerization and block copolymerization. These results offer a comprehensive mechanistic understanding of olefin metathesis, exemplifying infinite opportunities for practical precise manufacturing.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"164 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142598252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fully integrated multi-mode optoelectronic memristor array for diversified in-sensor computing","authors":"Heyi Huang, Xiangpeng Liang, Yuyan Wang, Jianshi Tang, Yuankun Li, Yiwei Du, Wen Sun, Jianing Zhang, Peng Yao, Xing Mou, Feng Xu, Jinzhi Zhang, Yuyao Lu, Zhengwu Liu, Jianlin Wang, Zhixing Jiang, Ruofei Hu, Ze Wang, Qingtian Zhang, Bin Gao, Xuedong Bai, Lu Fang, Qionghai Dai, Huaxiang Yin, He Qian, Huaqiang Wu","doi":"10.1038/s41565-024-01794-z","DOIUrl":"https://doi.org/10.1038/s41565-024-01794-z","url":null,"abstract":"<p>In-sensor computing, which integrates sensing, memory and processing functions, has shown substantial potential in artificial vision systems. However, large-scale monolithic integration of in-sensor computing based on emerging devices with complementary metal–oxide–semiconductor (CMOS) circuits remains challenging, lacking functional demonstrations at the hardware level. Here we report a fully integrated 1-kb array with 128 × 8 one-transistor one-optoelectronic memristor (OEM) cells and silicon CMOS circuits, which features configurable multi-mode functionality encompassing three different modes of electronic memristor, dynamic OEM and non-volatile OEM (NV-OEM). These modes are configured by modulating the charge density within the oxygen vacancies via synergistic optical and electrical operations, as confirmed by differential phase-contrast scanning transmission electron microscopy. Using this OEM system, three visual processing tasks are demonstrated: image sensory pre-processing with a recognition accuracy enhanced from 85.7% to 96.1% by the NV-OEM mode, more advanced object tracking with 96.1% accuracy using both dynamic OEM and NV-OEM modes and human motion recognition with a fully OEM-based in-sensor reservoir computing system achieving 91.2% accuracy. A system-level benchmark further shows that it consumes over 20 times less energy than graphics processing units. By monolithically integrating the multi-functional OEMs with Si CMOS, this work provides a cost-effective platform for diverse in-sensor computing applications.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"8 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142598262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineering modular and tunable single-molecule sensors by decoupling sensing from signal output","authors":"Lennart Grabenhorst, Martina Pfeiffer, Thea Schinkel, Mirjam Kümmerlin, Gereon A. Brüggenthies, Jasmin B. Maglic, Florian Selbach, Alexander T. Murr, Philip Tinnefeld, Viktorija Glembockyte","doi":"10.1038/s41565-024-01804-0","DOIUrl":"https://doi.org/10.1038/s41565-024-01804-0","url":null,"abstract":"<p>Biosensors play key roles in medical research and diagnostics. However, the development of biosensors for new biomolecular targets of interest often involves tedious optimization steps to ensure a high signal response at the analyte concentration of interest. Here we show a modular nanosensor platform that facilitates these steps by offering ways to decouple and independently tune the signal output as well as the response window. Our approach utilizes a dynamic DNA origami nanostructure to engineer a high optical signal response based on fluorescence resonance energy transfer. We demonstrate mechanisms to tune the sensor’s response window, specificity and cooperativity as well as highlight the modularity of the proposed platform by extending it to different biomolecular targets including more complex sensing schemes. This versatile nanosensor platform offers a promising starting point for the rapid development of biosensors with tailored properties.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"18 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142594195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted intervention in nerve–cancer crosstalk enhances pancreatic cancer chemotherapy","authors":"Jiaqi Qin, Jingjie Liu, Zhaohan Wei, Xin Li, Zhaoxia Chen, Jianye Li, Wenxia Zheng, Haojie Liu, Shiyi Xu, Tuying Yong, Ben Zhao, Shanmiao Gou, Shenghong Ju, Gao-Jun Teng, Xiangliang Yang, Lu Gan","doi":"10.1038/s41565-024-01803-1","DOIUrl":"https://doi.org/10.1038/s41565-024-01803-1","url":null,"abstract":"<p>Nerve–cancer crosstalk has gained substantial attention owing to its impact on tumour growth, metastasis and therapy resistance. Effective therapeutic strategies targeting tumour-associated nerves within the intricate tumour microenvironment remain a major challenge in pancreatic cancer. Here we develop <i>Escherichia coli</i> Nissle 1917-derived outer membrane vesicles conjugated with nerve-binding peptide NP41, loaded with the tropomyosin receptor kinase (Trk) inhibitor larotrectinib (Lar@NP-OMVs) for tumour-associated nerve targeting. Lar@NP-OMVs achieve efficient nerve intervention to diminish neurite growth by disrupting the neurotrophin/Trk signalling pathway. Moreover, OMV-mediated repolarization of M2-like tumour-associated macrophages to an M1-like phenotype results in nerve injury, further accentuating Lar@NP-OMV-induced nerve intervention to inhibit nerve-triggered proliferation and migration of pancreatic cancer cells and angiogenesis. Leveraging this strategy, Lar@NP-OMVs significantly reduce nerve infiltration and neurite growth promoted by gemcitabine within the tumour microenvironment, leading to augmented chemotherapy efficacy in pancreatic cancer. This study sheds light on a potential avenue for nerve-targeted therapeutic intervention for enhancing pancreatic cancer therapy.</p>","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"45 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}