Nature nanotechnology最新文献_第2页

Kramers versus Kramers makes a stable qubit

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-03-14 DOI: 10.1038/s41565-025-01876-6

Anasua Chatterjee

引用次数: 0

Electrically activating two-dimensional antiferromagnets

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-03-14 DOI: 10.1038/s41565-025-01884-6

Shi-Jing Gong, Cheng Gong

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Quantum-enabled microwave-to-optical transduction via silicon nanomechanics

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-03-13 DOI: 10.1038/s41565-025-01874-8

Han Zhao, William David Chen, Abhishek Kejriwal, Mohammad Mirhosseini

{"title":"Quantum-enabled microwave-to-optical transduction via silicon nanomechanics","authors":"Han Zhao, William David Chen, Abhishek Kejriwal, Mohammad Mirhosseini","doi":"10.1038/s41565-025-01874-8","DOIUrl":"https://doi.org/10.1038/s41565-025-01874-8","url":null,"abstract":"An interface between microwave and optical photons offers the potential to network remote superconducting quantum processors. To preserve fragile quantum states, a microwave-to-optical transducer must operate efficiently in the quantum-enabled regime by generating less than one photon of noise referred to its input. Here we achieve these criteria using an integrated electro-optomechanical device made from crystalline silicon. Our platform eliminates the need for heterogeneous integration with piezoelectric materials by utilizing electrostatic actuation of gigahertz-frequency nanomechanical oscillators. Leveraging the ultra-low mechanical dissipation in silicon, our microwave-to-optical transducers achieve below one photon of input-referred added noise (nadd = 0.58) under continuous-wave laser drives. This demonstration of continuous quantum-enabled microwave-to-optical transduction improves the upconversion rate by about two orders of magnitude beyond the state of the art (R = 0.47–1.9 kHz). The increased transduction rate and scalable fabrication of our devices may facilitate near-term use of transducers in distributed quantum computers and quantum networks.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"16 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Switching on and off the spin polarization of the conduction band in antiferromagnetic bilayer transistors

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-03-11 DOI: 10.1038/s41565-025-01872-w

Fengrui Yao, Menghan Liao, Marco Gibertini, Cheol-Yeon Cheon, Xiaohanwen Lin, Fan Wu, Kenji Watanabe, Takashi Taniguchi, Ignacio Gutiérrez-Lezama, Alberto F. Morpurgo

{"title":"Switching on and off the spin polarization of the conduction band in antiferromagnetic bilayer transistors","authors":"Fengrui Yao, Menghan Liao, Marco Gibertini, Cheol-Yeon Cheon, Xiaohanwen Lin, Fan Wu, Kenji Watanabe, Takashi Taniguchi, Ignacio Gutiérrez-Lezama, Alberto F. Morpurgo","doi":"10.1038/s41565-025-01872-w","DOIUrl":"https://doi.org/10.1038/s41565-025-01872-w","url":null,"abstract":"Antiferromagnetic conductors with suitably broken spatial symmetries host spin-polarized bands, which lead to transport phenomena commonly observed in metallic ferromagnets. In bulk materials, it is the given crystalline structure that determines whether symmetries are broken and spin-polarized bands are present. Here we show that, in the two-dimensional limit, an electric field can control the relevant symmetries. To this end, we fabricate a double-gate transistor based on bilayers of van der Waals antiferromagnetic semiconductor CrPS4 and show how a perpendicular electric displacement field can switch the spin polarization of the conduction band on and off. Because conduction band states with opposite spin polarizations are hosted in the different layers and are spatially separated, these devices also give control over the magnetization of the electrons that are accumulated electrostatically. Our experiments show that double-gated CrPS4 transistors provide a viable platform to create gate-induced conductors with near unity spin polarization at the Fermi level, as well as devices with a full electrostatic control of the total magnetization of the system.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"68 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143589596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanometre-resolution three-dimensional tomographic and vectorial near-field imaging in dielectric optical resonators

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-03-03 DOI: 10.1038/s41565-025-01873-9

Bingbing Zhu, Qingnan Cai, Yaxin Liu, Sheng Zhang, Weifeng Liu, Qiong He, Lei Zhou, Zhensheng Tao

引用次数: 0

All-anion electrolyte solutions for high-potential sodium batteries

IF 38.1 1区材料科学

Nature nanotechnology Pub Date : 2025-03-03 DOI: 10.1038/s41565-025-01869-5

Orynbay Zhanadilov, Seung-Taek Myung

引用次数: 0

A bioinspired polymeric membrane-enclosed insulin crystal achieves long-term, self-regulated drug release for type 1 diabetes therapy

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-02-26 DOI: 10.1038/s41565-025-01860-0

Jianchang Xu, Yang Zhang, Sheng Zhao, Juan Zhang, Yanfang Wang, Wei Liu, Kangfan Ji, Guangzheng Xu, Ping Wen, Xinwei Wei, Shaoqian Mei, Leihao Lu, Yuejun Yao, Feng Liu, Yufei Ma, Jiahuan You, Jianqing Gao, John B. Buse, Jinqiang Wang, Zhen Gu

{"title":"A bioinspired polymeric membrane-enclosed insulin crystal achieves long-term, self-regulated drug release for type 1 diabetes therapy","authors":"Jianchang Xu, Yang Zhang, Sheng Zhao, Juan Zhang, Yanfang Wang, Wei Liu, Kangfan Ji, Guangzheng Xu, Ping Wen, Xinwei Wei, Shaoqian Mei, Leihao Lu, Yuejun Yao, Feng Liu, Yufei Ma, Jiahuan You, Jianqing Gao, John B. Buse, Jinqiang Wang, Zhen Gu","doi":"10.1038/s41565-025-01860-0","DOIUrl":"https://doi.org/10.1038/s41565-025-01860-0","url":null,"abstract":"The nuclear envelope serves as a highly regulated gateway for macromolecule exchange between the nucleus and cytoplasm in eukaryotes. Here we have developed a cell nucleus-mimicking polymeric membrane-enclosed system for long and self-regulated therapy. A polymeric nano-membrane with nanopores is conformally synthesized in situ on the surface of each insulin crystal, ensuring sustained, adjustable and zero-order drug release kinetics. Glucose- and β-hydroxybutyrate-dually sensitive microdomains are integrated into the nano-membranes. Under a normal state, the microdomains are uncharged and the channel is narrow enough to block insulin outflow. Under hyperglycaemia and ketonaemia, microdomains convert the high glucose and β-hydroxybutyrate concentration signals to the negative electric potential of membranes, widening the nanopores with rapid insulin outflow. In type 1 diabetic mice and minipigs, this system can maintain normoglycaemia for longer than 1 month and 3 weeks, respectively, with validated glucose- and β-hydroxybutyrate-triggered insulin release. Such membrane-enclosed drug crystal/powder formulation provides a broad platform for long-acting controlled release.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"31 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term blood sugar control with smart insulin crystals

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-02-26 DOI: 10.1038/s41565-025-01871-x

引用次数: 0

Nanoscopic cross-grain cation homogenization in perovskite solar cells

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-02-24 DOI: 10.1038/s41565-025-01854-y

Mingwei Hao, Jonghee Yang, Wenjian Yu, Benjamin J. Lawrie, Pengfei Guo, Xiangzhao Zhang, Tianwei Duan, Tong Xiao, Linqi Chen, Yang Xiang, Peijun Guo, Mahshid Ahmadi, Yuanyuan Zhou

{"title":"Nanoscopic cross-grain cation homogenization in perovskite solar cells","authors":"Mingwei Hao, Jonghee Yang, Wenjian Yu, Benjamin J. Lawrie, Pengfei Guo, Xiangzhao Zhang, Tianwei Duan, Tong Xiao, Linqi Chen, Yang Xiang, Peijun Guo, Mahshid Ahmadi, Yuanyuan Zhou","doi":"10.1038/s41565-025-01854-y","DOIUrl":"https://doi.org/10.1038/s41565-025-01854-y","url":null,"abstract":"Multiscale cation inhomogeneity has been a major hurdle in state-of-the-art formamidinium–caesium (FA–Cs) mixed-cation perovskites for achieving perovskite solar cells with optimal power conversion efficiencies and durability. Although the field has attempted to homogenize the overall distributions of FA–Cs in perovskite films from both plan and cross-sectional views, our understanding of grain-to-grain cation inhomogeneity and ability to tailor it—that is, spatially resolving the FA–Cs compositional difference between individual grains down to the nanoscale—are lacking. Here we reveal that as fundamental building blocks of a perovskite film, individual grains exhibit cationic compositions deviating from the prescribed ideal composition, severely limiting the interfacial optoelectronic properties and perovskite layer durability. This performance-limiting nanoscopic factor is linked to thermodynamic-driven morphological grooving, leading to a segmented surface landscape. At the grain triple junctions, grooves form nanoscale groove traps that hinder the mixing of solid-state cations across grains and thus retard inter-grain FA–Cs mixing. By rationally modulating the heterointerfacial energies, we reduced the depth of these nanoscale groove traps by a factor of three, significantly improving cation homogeneity. Perovskite solar cells with shallower nanoscale groove traps demonstrate enhanced power conversion efficiencies (25.62%) and improved stability under various standardized international protocols. Our work highlights the significance of resolving surface nano-morphologies for homogeneous properties of perovskites.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"27 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-02-21 DOI: 10.1038/s41565-025-01867-7

Felix Alonso-Valenteen, Simoun Mikhael, HongQiang Wang, Jessica Sims, Michael Taguiam, James Teh, Sam Sances, Michelle Wong, Tianxin Miao, Dustin Srinivas, Nelyda Gonzalez-Almeyda, Ryan H. Cho, Romny Sanchez, Kimngan Nguyenle, Erik Serrano, Briana Ondatje, Rebecca L. Benhaghnazar, Harry B. Gray, Zeev Gross, John Yu, Clive N. Svendsen, Ravinder Abrol, Lali K. Medina-Kauwe

{"title":"Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth","authors":"Felix Alonso-Valenteen, Simoun Mikhael, HongQiang Wang, Jessica Sims, Michael Taguiam, James Teh, Sam Sances, Michelle Wong, Tianxin Miao, Dustin Srinivas, Nelyda Gonzalez-Almeyda, Ryan H. Cho, Romny Sanchez, Kimngan Nguyenle, Erik Serrano, Briana Ondatje, Rebecca L. Benhaghnazar, Harry B. Gray, Zeev Gross, John Yu, Clive N. Svendsen, Ravinder Abrol, Lali K. Medina-Kauwe","doi":"10.1038/s41565-025-01867-7","DOIUrl":"https://doi.org/10.1038/s41565-025-01867-7","url":null,"abstract":"Crossing the blood–brain barrier (BBB) and reaching intracranial tumours is a clinical challenge for current targeted interventions including antibody-based therapies, contributing to poor patient outcomes. Increased cell surface density of human epidermal growth factor receptor 3 (HER3) is associated with a growing number of metastatic tumour types and is observed on tumour cells that acquire resistance to a growing number of clinical targeted therapies. Here we describe the evaluation of HER3-homing nanobiological particles (nanobioparticles (NBPs)) on such tumours in preclinical models and our discovery that systemic NBPs could be found in the brain even in the absence of such tumours. Our subsequent studies described here show that HER3 is prominently associated with both mouse and human brain endothelium and with extravasation of systemic NBPs in mice and in human-derived BBB chips in contrast to non-targeted agents. In mice, systemically delivered NBPs carrying tumoricidal agents reduced the growth of intracranial triple-negative breast cancer cells, which also express HER3, with improved therapeutic profile compared to current therapies and compared to agents using traditional BBB transport routes. As HER3 associates with a growing number of metastatic tumours, the NBPs described here may offer targeted efficacy especially when such tumours localize to the brain.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"19 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143462378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0