Nature nanotechnology最新文献

{"title":"Evolution of multivalent supramolecular assemblies of aptamers with target-defined spatial organization","authors":"Artem Kononenko, Vincenzo Caroprese, Yoan Duhoo, Cem Tekin, Maartje M. C. Bastings","doi":"10.1038/s41565-025-01939-8","DOIUrl":"10.1038/s41565-025-01939-8","url":null,"abstract":"Rapid identification of neutralizing molecules against new and mutating viruses is key to efficiently combating biorisk. Current binder identification techniques use a monovalent library of potential binders. Interestingly, proteins on pathogens are often homo-oligomeric—for example, the SARS-CoV-2 spike protein is a homotrimer. Here we describe a simple strategy, MEDUSA (multivalent evolved DNA-based supramolecular assembly), to evolve multivalent assemblies of aptamers with precise interligand spacing and three-fold symmetry, mirroring the geometric structure of many viral capsid proteins. MEDUSA allowed the selection of potent SARS-CoV-2 spike binders structurally distinct from any known aptamers. Decoupling the geometric and structural rigidity contributions toward selectivity made it possible to connect form to function, as demonstrated by the design of tunable fluorescent sensors. This approach offers a blueprint for targeting geometrically defined pathogen structures and developing rapid-response tools for emerging pathogens. Expanding aptamer binder space through tunable directed coevolution of supramolecular scaffolds helps discover nucleic-acid-based multivalent target binders capable of synergistic engagement that cannot be obtained through monovalent selection.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"1087-1097"},"PeriodicalIF":34.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-025-01939-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanochemical carbon dioxide capture and conversion","authors":"Runnan Guan, Li Sheng, Changqing Li, Jiwon Gu, Jeong-Min Seo, Boo-Jae Jang, Seung-Hyeon Kim, Jiwon Kim, Hankwon Lim, Qunxiang Li, Jong-Beom Baek","doi":"10.1038/s41565-025-01949-6","DOIUrl":"10.1038/s41565-025-01949-6","url":null,"abstract":"Developing a direct carbon dioxide (CO2) capture and methanation method is one of the most important challenges to achieving carbon neutrality. However, converting CO2 into methane (CH4) kinetically requires the activation of stable CO2 at high temperatures (300–500 °C), while the CO2-to-CH4 conversion thermodynamically favours low temperatures. Here we report an efficient mechanochemical CO2 capture and conversion under mild conditions (65 °C). Using commercial zirconium oxide (ZrO2) and nickel catalysts, the mechanochemical CO2 capture capacity was 75-fold higher than the conventional thermochemical process. The mechanochemical CO2 conversion reached a nearly quantitative CO2 conversion (99.2%) with CH4 selectivity (98.8%). We determined that repeatedly induced abundant oxygen vacancies on ZrO2 by dynamic mechanical actions are responsible for efficient CO2 capture and, thus, subsequently spontaneous methanation. Carbon dioxide can be efficiently captured and converted to methane under mild conditions by a mechanochemical approach that balances the thermodynamics and kinetics of CO2 methanation to simultaneously achieve high CO2 conversion and high CH4 selectivity.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1247-1253"},"PeriodicalIF":34.9,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144218779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ferroelastic writing of crystal directions in oxide thin films","authors":"Wei Peng, Wenjie Meng, Younji Kim, Jiyong Yoon, Liang Si, Kesen Zhao, Shuai Dong, Yubin Hou, Chuanying Xi, Li Pi, Aditya Singh, Ana M. Sanchez, Richard Beanland, Tae Won Noh, Qingyou Lu, Daesu Lee, Marin Alexe","doi":"10.1038/s41565-025-01950-z","DOIUrl":"10.1038/s41565-025-01950-z","url":null,"abstract":"Crystals often have complex structural domains, but a general method to remove or deterministically control such local heterogeneity is lacking. The resulting heterogeneity in crystal orientations obscures our understanding of material properties and can reduce the reliability and performance of related applications. Here, using shear stress from an atomic force microscope tip, we ferroelastically write local crystal orientations in oxide thin films. Applying this deterministic and reversible control to SrRuO3 and (La0.7Sr0.3)(Mn0.9Ru0.1)O3 films, we realize twin-free single crystals and design specific crystal-orientation domain textures at the nanoscale. Furthermore, through magnetoelastic coupling, we can mechanically manipulate the local magnetic anisotropy, and thereby write and erase functional nanoscale magnetic textures unattainable by conventional methods. Thus, pure mechanical force emerges as a means to control structural heterogeneity on demand and may make it possible to program electronic and spintronic functionalities. Local shear stress from an atomic force microscope tip can control the crystal directions in thin oxide films. This approach enables the manipulation of local magnetic anisotropy in ferromagnetic metals.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1199-1204"},"PeriodicalIF":34.9,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-025-01950-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144218778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interfacial reaction quantification enables long-cycling lithium metal batteries","authors":"","doi":"10.1038/s41565-025-01938-9","DOIUrl":"10.1038/s41565-025-01938-9","url":null,"abstract":"A quantitative investigation of the interfacial reactions within lithium metal batteries (LMBs) reveals that the decomposition of lithium bis(fluorosulfonyl)imide leads to lithium-ion depletion and cell failure. Using these findings, an electrolyte was designed with an optimized salt concentration, ionic conductivity and dynamic viscosity, doubling the cycle life in a practical LMB.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"987-988"},"PeriodicalIF":34.9,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144211612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unidirectional guided resonance continuum of Dirac bands in WS2 bilayer metasurfaces","authors":"Daegwang Choi, Ki Young Lee, Dong-Jin Shin, Jae Woong Yoon, Su-Hyun Gong","doi":"10.1038/s41565-025-01945-w","DOIUrl":"10.1038/s41565-025-01945-w","url":null,"abstract":"Unidirectional guided resonances are crucial for enhancing the efficiency and performance of various photonic devices, such as couplers and antennas. However, unidirectional guided resonances have been reported only under discrete frequency–wavevector points on a dispersion band, which require accidental interference configurations. Here we show that unidirectional guided resonances can continuously exist across nearly the entire band structure in glide-symmetric bilayer metasurfaces. This continuous excitation of unidirectional guided resonances originates from a synergistic effect between anomalous orthogonality and vertically asymmetric geometry, which is achieved by a Dirac crossing band that preserves glide symmetry. We realize the glide-symmetric bilayer metasurfaces by stacking two WS2 metasurface layers. Angle-resolved emission spectra directly reveal this unidirectional guided resonance continuum. Our work suggests a fundamental solution to existing narrow-band constraints on unidirectional emission and absorption. Unidirectional guided resonances can exist across nearly the entire band structure in glided WS2 bilayer metasurfaces.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"1026-1033"},"PeriodicalIF":34.9,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144211614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vivo transformations of positively charged nanoparticles alter the formation and function of RuBisCO photosynthetic protein corona","authors":"Christopher Castillo, Su-Ji Jeon, Khoi Nguyen L. Hoang, Claire Alford, Erica Svendahl, Chaoyi Deng, Yi Wang, Yinhan Wang, Xingfei Wei, Rigoberto Hernandez, Jason C. White, Korin E. Wheeler, Catherine J. Murphy, Juan Pablo Giraldo","doi":"10.1038/s41565-025-01944-x","DOIUrl":"10.1038/s41565-025-01944-x","url":null,"abstract":"The impact of nanomaterial transformations on photosynthetic proteins remains largely unknown. We report positively charged iron oxide (Fe3O4) nanoparticles experience transformations in Arabidopsis thaliana plants in vivo that alter the formation and function of RuBisCO protein corona, a key carbon fixation enzyme. In vitro, negatively charged Fe3O4 nanoparticles impact the RuBisCO function but not their positively charged counterparts. Computational and in vitro proteomic analyses revealed that positively charged Fe3O4 nanoparticles preferentially bind to a RuBisCO small subunit that lacks active carboxylation sites. However, both positively and negatively charged nanoparticles decrease RuBisCO carboxylation activity after experiencing transformations in vivo by 3.0 and 1.7 times relative to the controls, respectively. The pH- and lipid-coating-dependent transformations that occur during nanoparticle transport across plant membranes enhance RuBisCO binding to positively charged nanoparticles affecting its distribution in chloroplasts. Elucidating the rules of how nanoparticle properties and transformations affect photosynthetic coronas is crucial for sustainable nano-enabled agriculture. Experimental and computational analyses indicated that positively charged nanoparticles experience pH- and lipid-coating-dependent transformations in plants that modify their impact on RuBisCO photosynthetic protein corona formation and function.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"1152-1162"},"PeriodicalIF":34.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic nanodomains dictate macroscopic properties in lead halide perovskites","authors":"Milos Dubajic, James R. Neilson, Johan Klarbring, Xia Liang, Stephanie A. Bird, Kirrily C. Rule, Josie E. Auckett, Thomas A. Selby, Ganbaatar Tumen-Ulzii, Yang Lu, Young-Kwang Jung, Cullen Chosy, Zimu Wei, Yorrick Boeije, Martin v. Zimmermann, Andreas Pusch, Leilei Gu, Xuguang Jia, Qiyuan Wu, Julia C. Trowbridge, Eve M. Mozur, Arianna Minelli, Nikolaj Roth, Kieran W. P. Orr, Arman Mahboubi Soufiani, Simon Kahmann, Irina Kabakova, Jianning Ding, Tom Wu, Gavin J. Conibeer, Stephen P. Bremner, Michael P. Nielsen, Aron Walsh, Samuel D. Stranks","doi":"10.1038/s41565-025-01917-0","DOIUrl":"10.1038/s41565-025-01917-0","url":null,"abstract":"Lead halide perovskites have emerged as promising materials for solar energy conversion and X-ray detection owing to their remarkable optoelectronic properties. However, the microscopic origins of their superior performance remain unclear. Here we show that low-symmetry dynamic nanodomains present in the high-symmetry average cubic phases, whose characteristics are dictated by the A-site cation, govern the macroscopic behaviour. We combine X-ray diffuse scattering, inelastic neutron spectroscopy, hyperspectral photoluminescence microscopy and machine-learning-assisted molecular dynamics simulations to directly correlate local nanoscale dynamics with macroscopic optoelectronic response. Our approach reveals that methylammonium-based perovskites form densely packed, anisotropic dynamic nanodomains with out-of-phase octahedral tilting, whereas formamidinium-based systems develop sparse, isotropic, spherical nanodomains with in-phase tilting, even when crystallography reveals cubic symmetry on average. We demonstrate that these sparsely distributed isotropic nanodomains present in formamidinium-based systems reduce electronic dynamic disorder, resulting in a beneficial optoelectronic response, thereby enhancing the performance of formamidinium-based lead halide perovskite devices. By elucidating the influence of the A-site cation on local dynamic nanodomains, and consequently, on the macroscopic properties, we propose leveraging this relationship to engineer the optoelectronic response of these materials, propelling further advancements in perovskite-based photovoltaics, optoelectronics and X-ray imaging. Dynamic nanodomains in lead halide perovskites, dictated by A-site cations, crucially affect the optoelectronic properties by modulating electronic disorder and consequently enabling better solar cells and optoelectronic devices.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 6","pages":"755-763"},"PeriodicalIF":34.9,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-025-01917-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144193129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application-driven design of non-aqueous electrolyte solutions through quantification of interfacial reactions in lithium metal batteries","authors":"Hansen Wang, Xiaolin Yan, Rupeng Zhang, Juanjuan Sun, Fuxiang Feng, Haoran Li, Jinding Liang, Yuchun Wang, Guangzhou Ye, Xiaonan Luo, Shengyuan Huang, Pan Wan, Samantha T. Hung, Fangjun Ye, Fangyun Chen, Erxiao Wu, Jinfei Zhou, Ulderico Ulissi, Xiaoming Ge, Chengyong Liu, Bo Xu, Na Liu, Chuying Ouyang","doi":"10.1038/s41565-025-01935-y","DOIUrl":"10.1038/s41565-025-01935-y","url":null,"abstract":"Unwanted side reactions occurring at electrode|electrolyte interfaces significantly impact the cycling life of lithium metal batteries. However, a comprehensive view that rationalizes these interfacial reactions and assesses them both qualitatively and quantitatively is not yet established. Here, by combining multiple analytical techniques, we systematically investigate the interfacial reactions in lithium metal batteries containing ether-based non-aqueous electrolyte solutions. We quantitatively monitor various nanoscale-driven processes such as the reduction and oxidation pathways of lithium salt and organic solvents, the formation of various solid-electrolyte interphase species, the gas generation within the cell and the cross-talk processes between the electrodes. We demonstrate that the consumption of lithium ions owing to the continuous decomposition of the lithium bis(fluorosulfonyl)imide salt, which dominates the interfacial reactions, results in ion depletion during the cell discharge and battery failure. On the basis of these findings, we propose an electrolyte formulation in which lithium bis(fluorosulfonyl)imide content is maximized without compromising dynamic viscosity and bulk ionic conductivity, aiming for long-cycling battery performance. Following this strategy, we assemble and test Li (20 μm thickness)||LiNi0.8Mn0.1Co0.1O2 (17.1 mg cm−2 of active material) single-layer stack pouch cells in lean electrolyte conditions (that is, 2.1 g Ah−1), which can effectively sustain 483 charge (0.2 C or 28 mA)/discharge (1 C or 140 mA) cycles at 25 °C demonstrating a discharge capacity retention of about 77%. Tailored non-aqueous electrolyte solutions are formulated using data obtained from extensive analytical measurements and analyses. These optimized electrolytes improve the cycling performance of single-layer stack lithium metal pouch cells, particularly in lean electrolyte conditions.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"1034-1042"},"PeriodicalIF":34.9,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-025-01935-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twisted light with a designed polar topology","authors":"Qian Li, Jingbo Sun","doi":"10.1038/s41565-025-01927-y","DOIUrl":"10.1038/s41565-025-01927-y","url":null,"abstract":"Ferroelectric membranes of BaTiO3 can form centre-convergent polar topology domes that couple with light to generate circularly polarized beams.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 7","pages":"859-860"},"PeriodicalIF":34.9,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supramolecular polymerization through rotation of light-driven molecular motors","authors":"Philippe Schiel, Mounir Maaloum, Emilie Moulin, Irina Nyrkova, Alexander Semenov, Damien Dattler, Lou-Ann Accou, Anastasia Christoulaki, Eric Buhler, Rémi Plamont, Jean-Marie Lehn, Nicolas Giuseppone","doi":"10.1038/s41565-025-01933-0","DOIUrl":"10.1038/s41565-025-01933-0","url":null,"abstract":"Molecular motors can act on their environment through their unique ability to generate non-reciprocal autonomous motions at the nanoscale. Although their operating principles are now understood, artificial molecular motors have yet to demonstrate their general capacity to confer novel properties on (supra)molecular systems and materials. Here we show that amphiphilic light-driven molecular motors can adsorb onto an air‒water interface and form Langmuir monolayers upon compression. By irradiation with ultraviolet light, the surface pressure isotherms of these films reveal a drastic shift toward a smaller molecular area as a consequence of motor activation. We explain this counterintuitive phenomenon by the rotation-induced supramolecular polymerization of amphiphilic motors through a non-thermal annealing process to escape a kinetically trapped amorphous state. The effect is limited by the maximum torque the molecular motor can deliver (~10 pN nm) and leads to the formation of highly organized patterns. This serendipitous discovery highlights the opportunities offered by molecular motors to control supramolecular polymerization for the design of innovative materials. An amphiphilic light-driven rotary motor is shown to form Langmuir monolayers at the air–water interface. Upon ultraviolet irradiation, the continuous rotation of the motor triggers its supramolecular polymerization and subsequent nanopatterning of the interfacial layer.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"1052-1061"},"PeriodicalIF":34.9,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}