Nature Catalysis最新文献_第10页

Author Correction: Epistasis arises from shifting the rate-limiting step during enzyme evolution of a β-lactamase 作者更正：β-内酰胺酶酶进化过程中限速步骤的移动产生了外显子效应

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-05-02 DOI: 10.1038/s41929-024-01170-z

Christopher Fröhlich, H. Adrian Bunzel, Karol Buda, Adrian J. Mulholland, Marc W. van der Kamp, Pål J. Johnsen, Hanna-Kirsti S. Leiros, Nobuhiko Tokuriki

引用次数: 0

Catalytic atroposelective synthesis 催化丙选择性合成

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-30 DOI: 10.1038/s41929-024-01138-z

Shao-Hua Xiang, Wei-Yi Ding, Yong-Bin Wang, Bin Tan

{"title":"Catalytic atroposelective synthesis","authors":"Shao-Hua Xiang, Wei-Yi Ding, Yong-Bin Wang, Bin Tan","doi":"10.1038/s41929-024-01138-z","DOIUrl":"10.1038/s41929-024-01138-z","url":null,"abstract":"Atropisomeric architectures are increasingly encountered in modern materials and medicinally important compounds. More importantly, they are now a characteristic of broadly useful chiral ligands and organocatalysts. Over the past decade, substantial advancements have been made in enhancing the accessibility of major classes of atropisomers through the refinement of existing strategies and the introduction of contemporary concepts for catalytic atroposelective synthesis. This synthetic capability enables the expansion of chemical space and facilitates the preparation of valuable atropisomeric scaffolds. Here we review the state of the art in the asymmetric synthesis of atropisomers with the help of selected examples. Focus will be placed on the strategies that have emerged rapidly in recent years, and that are characterized by high versatility and modularity. Additionally, the incorporation of emerging synthetic tools and representative scaffolds are discussed, alongside future directions in this research domain. Atropisomerism is an expanding target of asymmetric catalysis. In this Review, recent advances in atroposelective synthesis under catalytic control are highlighted with a focus on general strategies that provide high versatility and modularity.","PeriodicalId":18845,"journal":{"name":"Nature Catalysis","volume":null,"pages":null},"PeriodicalIF":37.8,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140814377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nickel-catalysed enantioselective alkene dicarbofunctionalization enabled by photochemical aliphatic C–H bond activation 通过光化学脂肪族 C-H 键活化实现镍催化的对映体选择性烯烃二卡伯功能化

IF 42.8 1区化学

Nature Catalysis Pub Date : 2024-04-29 DOI: 10.1038/s41929-024-01153-0

Xia Hu, Iván Cheng-Sánchez, Wangqing Kong, Gary A. Molander, Cristina Nevado

{"title":"Nickel-catalysed enantioselective alkene dicarbofunctionalization enabled by photochemical aliphatic C–H bond activation","authors":"Xia Hu, Iván Cheng-Sánchez, Wangqing Kong, Gary A. Molander, Cristina Nevado","doi":"10.1038/s41929-024-01153-0","DOIUrl":"10.1038/s41929-024-01153-0","url":null,"abstract":"The development of novel strategies to rapidly construct complex chiral molecules from readily available feedstocks is a long-term pursuit in the chemistry community. Radical-mediated alkene difunctionalizations represent an excellent platform towards this goal. However, asymmetric versions remain highly challenging, and more importantly, examples featuring simple hydrocarbons as reaction partners are elusive. Here we report an asymmetric three-component alkene dicarbofunctionalization capitalizing on the direct activation of C(sp3)–H bonds through the combination of photocatalysed hydrogen atom transfer and nickel catalysis. This protocol provides an efficient platform for installing two vicinal carbon–carbon bonds across alkenes in an atom-economic fashion, providing a wide array of high-value chiral α-aryl/alkenyl carbonyls and phosphonates, as well as 1,1-diarylalkanes from ubiquitous alkane, ether and alcohol feedstocks. This method exhibits operational simplicity, broad substrate scope and excellent regioselectivity, chemoselectivity and enantioselectivity. The compatibility with bioactive motifs and expedient synthesis of pharmaceutically relevant molecules highlight the synthetic potential of this protocol. Asymmetric versions of radical-mediated alkene difunctionalizations featuring hydrocarbon precursors are currently elusive. Here the authors report an asymmetric vicinal alkene dicarbofunctionalization based on the activation of C(sp3)–H bonds through the combination of photocatalysed hydrogen atom transfer and nickel catalysis.","PeriodicalId":18845,"journal":{"name":"Nature Catalysis","volume":null,"pages":null},"PeriodicalIF":42.8,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41929-024-01153-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140808364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Murder on the micropore 微孔谋杀案

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01159-8

Marçal Capdevila-Cortada

引用次数: 0

Author Correction: Stabilization of layered lithium-rich manganese oxide for anion exchange membrane fuel cells and water electrolysers 作者更正：用于阴离子交换膜燃料电池和水电解槽的层状富锂锰氧化物的稳定化

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01166-9

Xuepeng Zhong, Lijun Sui, Menghao Yang, Toshinari Koketsu, Malte Klingenhof, Sören Selve, Kyle G. Reeves, Chuangxin Ge, Lin Zhuang, Wang Hay Kan, Maxim Avdeev, Miao Shu, Nicolas Alonso-Vante, Jin-Ming Chen, Shu-Chih Haw, Chih-Wen Pao, Yu-Chung Chang, Yunhui Huang, Zhiwei Hu, Peter Strasser, Jiwei Ma

引用次数: 0

Bubble trouble 气泡问题

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01158-9

Benjamin Martindale

引用次数: 0

Acetyl-CoA-independent malonyl-CoA biosynthesis 乙酰-CoA 独立丙二酰-CoA 生物合成

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01139-y

Dongsoo Yang

引用次数: 0

Performance evaluation and multidisciplinary analysis of catalytic fixation reactions by material–microbe hybrids 材料-微生物混合物催化固定反应的性能评估和多学科分析

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01151-2

Xun Guan, Yongchao Xie, Chong Liu

{"title":"Performance evaluation and multidisciplinary analysis of catalytic fixation reactions by material–microbe hybrids","authors":"Xun Guan, Yongchao Xie, Chong Liu","doi":"10.1038/s41929-024-01151-2","DOIUrl":"10.1038/s41929-024-01151-2","url":null,"abstract":"Hybrid systems that integrate synthetic materials with biological machinery offer opportunities for sustainable and efficient catalysis. However, the multidisciplinary and unique nature of the materials–biology interface requires researchers to draw insights from different fields. In this Perspective, using examples from the area of N2 and CO2 fixation, we provide a unified discussion of critical aspects of the material–microbe interface, simultaneously considering the requirements of physical and biological sciences that have a tangible impact on the performance of biohybrids. We first discuss the figures of merit and caveats for the evaluation of catalytic performance. Then, we reflect on the interactions and potential synergies at the materials–biology interface, as well as the challenges and opportunities for a deepened fundamental understanding of abiotic–biotic catalysis. Material–microbe hybrids represent an interesting class of catalyst with potential for high energy efficiency and product selectivity. In this Perspective the authors discuss some of the difficulties in understanding these interdisciplinary systems and the attempts to unify the approaches taken by different research communities to further the field.","PeriodicalId":18845,"journal":{"name":"Nature Catalysis","volume":null,"pages":null},"PeriodicalIF":37.8,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140648710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Taking a walk to find new mucinases 漫步寻找新的粘蛋白酶

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01145-0

Shinya Fushinobu

引用次数: 0

Tailored for semi-hydrogenation 专为半氢化设计

IF 37.8 1区化学

Nature Catalysis Pub Date : 2024-04-26 DOI: 10.1038/s41929-024-01146-z

Haisong Feng, Xin Zhang

引用次数: 0