Journal of Biophotonics最新文献_第5页

Parameter-Tuned Pulsed Wave Photobiomodulation Enhances Stem Cells From Apical Papilla Differentiation: Evidence From Gene and Protein Analyses 参数调谐脉冲波光生物调节促进根尖乳头分化干细胞：来自基因和蛋白质分析的证据。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-14 DOI: 10.1002/jbio.202400348

Moon-Ho Kang, Hong Bae Kim, Jong Hoon Chung, Pill-Hoon Choung

引用次数: 0

Zerumbone Induces Apoptosis in Non-Small-Cell Lung Cancer via Biomolecular Alterations: A Microscopic and Spectroscopic Study 泽润邦通过生物分子改变诱导非小细胞肺癌细胞凋亡：一项显微镜和光谱学研究。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-14 DOI: 10.1002/jbio.202400500

Çağla Zübeyde Köprü, Burcu Baba, Dilek Yonar

{"title":"Zerumbone Induces Apoptosis in Non-Small-Cell Lung Cancer via Biomolecular Alterations: A Microscopic and Spectroscopic Study","authors":"Çağla Zübeyde Köprü, Burcu Baba, Dilek Yonar","doi":"10.1002/jbio.202400500","DOIUrl":"10.1002/jbio.202400500","url":null,"abstract":"<div>\u0000 \u0000 <p>Zerumbone is a sesquiterpene phytochemical with cytotoxic activity against cancer. This study aimed to evaluate the effect of zerumbone on cell viability by WST-1 test, apoptosis by TUNEL, lipid peroxidation markers (malondialdehyde, MDA, and 4-hydroxynonenal, HNE) by using assay kits, and biomolecular changes by ATR-FTIR spectroscopy in A549 cells. After zerumbone (0–100 μM) incubation for 24, 48, and 72 h, the number of TUNEL-positive cells was found to be higher in zerumbone-treated cells than in controls, in consistent with cell morphology results. MDA levels increased significantly, although HNE levels increased non-significantly in zerumbone-treated cells. Spectral analyses revealed that the zerumbone-treated groups had higher levels of total saturated and unsaturated lipids as well as comparatively shorter-chain lipids. On the contrary, reduced RNA/DNA ratio, total nucleic acid, and protein content were found in zerumbone-treated groups. Consequently, zerumbone-induced apoptosis was accompanied by increased aldehyde products during lipid peroxidation as well as biomolecular alterations.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142981084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of a Single-Element Scanning System for Enhanced Photoacoustic Imaging of Brain Hemorrhage 评估用于脑出血增强光声成像的单元素扫描系统

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-13 DOI: 10.1002/jbio.202400153

Juliana Benavides Lara, Ravi Prakash, Kamran Avanaki

引用次数: 0

Neuronal Imaging at 8-Bit Depth to Combine High Spatial and High Temporal Resolution With Acquisition Rates Up To 40 kHz 神经元成像在8位深度结合高空间和高时间分辨率与采集率高达40 kHz。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-10 DOI: 10.1002/jbio.202400513

Fatima Abbas, Ömer Yusuf İpek, Philippe Moreau, Marco Canepari

引用次数: 0

Ion-Regulated Signal Amplification Optical Microfiber Interferometric DNA Sensor 离子调节信号放大光学微光纤干涉DNA传感器。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-07 DOI: 10.1002/jbio.202400389

Hanglin Lu, Li Yang, Yuanpeng Li, Jian Tang, Laipeng Shao, Kepeng Fu, Jinpeng Wei, Yalan Niu, Juihui Hu

{"title":"Ion-Regulated Signal Amplification Optical Microfiber Interferometric DNA Sensor","authors":"Hanglin Lu, Li Yang, Yuanpeng Li, Jian Tang, Laipeng Shao, Kepeng Fu, Jinpeng Wei, Yalan Niu, Juihui Hu","doi":"10.1002/jbio.202400389","DOIUrl":"10.1002/jbio.202400389","url":null,"abstract":"<div>\u0000 \u0000 <p>Genetic information sensors play a pivotal role in the biomedical field. The detection of deoxyribonucleic acid (DNA) is achieved experimentally using an optical microfiber interferometric sensor, which operates based on an ion-regulation sensitivity enhancement mechanism. The optical microfiber is fabricated by drawing optical fiber into a diameter of less than 10 μm via the melting and tapering technique. Leveraging the characteristics of monovalent cations can effectively promote the folding of G-rich single-stranded DNA (ssDNA) into stable G-quadruplex structures, enabling the detection of specific sequences of ssDNA at low concentrations. The results show an improvement of the linear detection range by 3 orders of magnitude, and with the introduction of the ion-regulation sensitivity enhancement mechanism, the limit of detection (LOD) value is 1.07 × 10<sup>−15</sup> M. This optical microfiber interferometric sensing architecture is characterized by its simplicity and high sensitivity, positioning it as a formidable tool for diverse biosensing and analytical applications.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mueller-Matrix Interferometric Multifractal Scaling of Optically Anisotropic Architectonics of Diffuse Blood Facies: Fundamental and Applied Aspects 弥漫性血相光学各向异性结构的mueller -矩阵干涉多重分形标度：基础与应用

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-06 DOI: 10.1002/jbio.202400412

Yurii Ushenko, Alexander Ushenko, Alexander Dubolazov, Iryna Soltys, Olexandra Litvinenko, Oleh Wanchuliak, Yulia Sarkisova, Ivan Mikirin, Olexander Salega, Jun Zheng, Lin Bin

{"title":"Mueller-Matrix Interferometric Multifractal Scaling of Optically Anisotropic Architectonics of Diffuse Blood Facies: Fundamental and Applied Aspects","authors":"Yurii Ushenko, Alexander Ushenko, Alexander Dubolazov, Iryna Soltys, Olexandra Litvinenko, Oleh Wanchuliak, Yulia Sarkisova, Ivan Mikirin, Olexander Salega, Jun Zheng, Lin Bin","doi":"10.1002/jbio.202400412","DOIUrl":"10.1002/jbio.202400412","url":null,"abstract":"<div>\u0000 \u0000 <p>The article describes a technique for digital holographic reconstruction of complex amplitude fields in diffuse blood facies using laser polarization-interference phase scanning to isolate a single scattered component of the object field. This method serves as the basis for developing algorithms for Mueller-matrix reconstruction of linear and circular birefringence parameters in the polycrystalline architectonics of blood facies. Statistical (central moments of the 1st–4th orders) and multifractal analyses (fractal dimension spectra) are applied to study the optical anisotropy maps of polycrystalline networks during blood dehydration. The study explores a practical application in the differential diagnosis of blood loss volume, identifying higher-order central moments (skewness, kurtosis) as sensitive markers. The method achieved a maximum accuracy of 92.9% in differentiating blood loss volume.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integration of Optical Coherence Tomography Images and Real-Life Clinical Data for Deep Learning Modeling: A Unified Approach in Prognostication of Diabetic Macular Edema 整合光学相干断层扫描图像和真实临床数据的深度学习建模：糖尿病黄斑水肿预后的统一方法。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-29 DOI: 10.1002/jbio.202400315

Muhammed Enes Atik, İbrahim Kocak, Nihat Sayin, Sadik Etka Bayramoglu, Ahmet Ozyigit

{"title":"Integration of Optical Coherence Tomography Images and Real-Life Clinical Data for Deep Learning Modeling: A Unified Approach in Prognostication of Diabetic Macular Edema","authors":"Muhammed Enes Atik, İbrahim Kocak, Nihat Sayin, Sadik Etka Bayramoglu, Ahmet Ozyigit","doi":"10.1002/jbio.202400315","DOIUrl":"10.1002/jbio.202400315","url":null,"abstract":"<div>\u0000 \u0000 <p>The primary ocular effect of diabetes is diabetic retinopathy (DR), which is associated with diabetic microangiopathy. Diabetic macular edema (DME) can cause vision loss for people with DR. For this reason, deciding on the appropriate treatment and follow-up has a critical role in terms of curing the disease. Current artificial intelligence (AI) approaches focus on OCT images and may ignore clinical, laboratory, and demographic information obtained by the specialist. This study presents a novel deep learning (DL) framework for evaluating the visual outcome of the TREX anti-VEGF intravitreal injection regimen. DL models are trained to extract deep features from OCT and ILM topographic images and the obtained deep features are combined with patients' demographic, clinical, and laboratory findings to predict the direction of the treatment process. When the ResNet-18 network is used, the proposed DL framework is able to predict the prognosis status of patients with the highest accuracy.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polarization Imaging Method for Detection of Lung Cancer Based on Symmetrical Single LCVR 基于对称单LCVR的肺癌偏振成像检测方法

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-29 DOI: 10.1002/jbio.202400470

Yuan Song, Danfei Huang, Tianyi Wang, Yi Xie, Dong Song, Jinghui Hong, Yushi Yang, Jiaxuan Yan

引用次数: 0

Prototype of Implant for Nitric Oxide Release Controlled by Infrared Radiation in Therapeutic Window 在治疗窗口通过红外线辐射控制一氧化氮释放的植入物原型。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-25 DOI: 10.1002/jbio.202400455

Natalia A. Virts, Tatyana Yu. Karogodina, Mikhail A. Panfilov, Alexey Yu. Vorob'ev, Alexander E. Moskalensky

{"title":"Prototype of Implant for Nitric Oxide Release Controlled by Infrared Radiation in Therapeutic Window","authors":"Natalia A. Virts, Tatyana Yu. Karogodina, Mikhail A. Panfilov, Alexey Yu. Vorob'ev, Alexander E. Moskalensky","doi":"10.1002/jbio.202400455","DOIUrl":"10.1002/jbio.202400455","url":null,"abstract":"<div>\u0000 \u0000 <p>Local therapeutic action and targeted drug release are promising approaches compared to traditional systemic drug administration. This is especially relevant for nitric oxide (NO), as its effects change dramatically depending on concentration and cellular context. Materials capable of releasing NO in deep tissues in a controlled manner might open new therapeutic opportunities. Light-sensitive NO donors represent a fascinating class of compounds with significant potential for precise and controlled NO release. However, most of them are sensitive to visible light, with only a few examples absorbing in a near-infrared therapeutic window. Here, we present the proof-of-concept of soft implants consisting of the photon upconverting core and the outer shell loaded with visible-light triggered NO donor. The separation into two compartments results in efficient energy harvesting by the dye and effective NO release under 980 nm infrared irradiation. Such implants could be used in smart therapies implying well-controlled and localized NO release.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Validation of a Multimodal Diffuse Reflectance and Spatially Offset Raman Spectroscopy System for In Vivo Applications 体内应用的多模态漫反射和空间偏移拉曼光谱系统的设计和验证。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-25 DOI: 10.1002/jbio.202400333

April Mordi, Varsha Karunakaran, Umme Marium Mim, Eric Marple, Narasimhan Rajaram

{"title":"Design and Validation of a Multimodal Diffuse Reflectance and Spatially Offset Raman Spectroscopy System for In Vivo Applications","authors":"April Mordi, Varsha Karunakaran, Umme Marium Mim, Eric Marple, Narasimhan Rajaram","doi":"10.1002/jbio.202400333","DOIUrl":"10.1002/jbio.202400333","url":null,"abstract":"<p>We report on the development of a multimodal spectroscopy system, combining diffuse reflectance spectroscopy (DRS) and spatially offset Raman spectroscopy (SORS). A fiber optic probe was designed with spatially offset source–detector fibers to collect subsurface measurements for each modality, as well as ball lens-coupled fibers for superficial measurements. The system acquires DRS, zero-offset Raman spectroscopy (RS) and SORS with good signal-to-noise ratio. Measurements on chicken breast tissue demonstrate that both DRS and RS can acquire spectra from similar depths within tissue. Measurements acquired from the skin of a human volunteer demonstrate distinct Raman peaks at 937 and 1755 cm<sup>−1</sup> that were unique to the zero-offset ball lens configuration and 718 and 1089 cm<sup>−1</sup> for the spatially offset setting. We also identified Raman peaks corresponding to melanin that were prominent in the superficial measurements obtained with the ball lens-coupled fibers but not in the spatially offset fibers.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0