Magnetic Resonance in Medical Sciences最新文献

{"title":"Morphological Observation of the Pupal Body of Trypoxylus dichotomus Using 9.4T MR Imaging.","authors":"Shoto Ikegami, Dai Ishiyama, Yoshiki Oda, Kinuko Niihara, Masafumi Yoshida, Keiichi Honda, Takashi A Inoue, Kagayaki Kuroda","doi":"10.2463/mrms.bc.2022-0070","DOIUrl":"10.2463/mrms.bc.2022-0070","url":null,"abstract":"<p><p>Metamorphosis in the pupae of the Trypoxylus dichotomus was continuously observed at 9.4T until their emergence. A large liquid-like mass occupied most of the volume in the trunk, while the surrounding tissue already existed at the beginning of the observation period. As the mass shrunk, tissues such as flight muscle formed, whereas the reservoir became prolonged to form the intestinal tract. This implies that the liquid-like mass worked as the raw material for creating adult tissues.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10681257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MR Imaging Findings of Uterine Adenomatoid Tumors.","authors":"Mayumi Takeuchi, Kenji Matsuzaki, Yoshimi Bando, Masafumi Harada","doi":"10.2463/mrms.mp.2022-0067","DOIUrl":"10.2463/mrms.mp.2022-0067","url":null,"abstract":"<p><strong>Purpose: </strong>Adenomatoid tumor is a rare benign genital tract neoplasm of mesothelial origin. Uterine adenomatoid tumors occur in the outer myometrium and may mimic leiomyomas. Because hormonal treatment is not applicable to adenomatoid tumors and laparoscopic enucleation is not easy as myomectomy, it is important to differentiate adenomatoid tumors from leiomyomas for the adequate treatment. The purpose of this study is to evaluate the MRI findings of adenomatoid tumor for the differentiation from leiomyoma.</p><p><strong>Methods: </strong>MRI findings of surgically proven 10 uterine adenomatoid tumors in 9 women were retrospectively evaluated with correlation to histopathological findings.</p><p><strong>Results: </strong>All 10 tumors appeared as solid myometrial masses and showed heterogeneous signal intensity with admixture of partially ill-defined slight high-intensity areas containing abundant tubular tumor cells and well-defined myoma-like low-intensity areas reflecting smooth muscle hypertrophy on T2WI including 4 lesions with peripheral ring-like high intensity. High-intensity areas on T2WI tended to show high intensity on diffusion-weighted imaging (DWI) with relatively high apparent diffusion coefficient (ADC), suggesting T2 shine-through effect due to abundant tubules. Intra-tumoral hemorrhage revealed on MRI was rare. Early intense contrast-enhanced areas on dynamic contrast-enhanced study were observed dominantly within the high-intensity areas but rarely within the low-intensity areas on T2WI.</p><p><strong>Conclusion: </strong>The outer myometrial mass with the admixture of well-defined low- and ill-defined high-intensity areas on T2WI may be suggestive of adenomatoid tumor. Peripheral ring-like high intensity on T2WI and DWI may also be suggestive. Dynamic contrast-enhanced MR study may be helpful for the differentiation from leiomyoma.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10618771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cortical Brush Sign: A Novel Finding on Thin-slice 3T Susceptibility-weighted Imaging in Acute Cerebral Infarct and Cerebral Venous Thrombosis.","authors":"Seiya Kishi, Masayuki Maeda, Fumine Tanaka, Ryota Kogue, Maki Umino, Hajime Sakuma","doi":"10.2463/mrms.bc.2022-0120","DOIUrl":"10.2463/mrms.bc.2022-0120","url":null,"abstract":"<p><p>We observed a new SWI finding, \"cortical brush sign,\" that represents prominent venous structures in the cortex of patients with acute cerebral infarct with or without moyamoya disease and cerebral venous thrombosis. The cortical brush sign disappeared on follow-up SWI in all cases. Cortical brush sign may help to understand the pathophysiology of venous structures in the cortex at acute phase.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10623631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associating the Severity of Emphysema with Coronary Flow Reserve and Left Atrial Conduit Function for the Emphysema Patients with Known or Suspected Coronary Artery Disease.","authors":"Makiko Kubooka, Masaki Ishida, Masafumi Takafuji, Haruno Ito, Takanori Kokawa, Satoshi Nakamura, Kensuke Domae, Suguru Araki, Yasutaka Ichikawa, Shuichi Murashima, Hajime Sakuma","doi":"10.2463/mrms.mp.2022-0025","DOIUrl":"10.2463/mrms.mp.2022-0025","url":null,"abstract":"<p><strong>Purpose: </strong>Pulmonary emphysema may associate with ischemic heart disease through systemic microvascular abnormality as a common pathway. Stress cardiovascular MR (CMR) allows for the assessment of global coronary flow reserve (CFR). The purpose of this study was to evaluate the association between the emphysema severity and the multiple MRI parameters in the emphysema patients with known or suspected coronary artery disease (CAD).</p><p><strong>Methods: </strong>A total of 210 patients with known or suspected CAD who underwent both 3.0T CMR including cine CMR, stress and rest perfusion CMR, stress and rest phase-contrast (PC) cine CMR of coronary sinus, and late gadolinium enhancement (LGE) CMR, and lung CT within 6 months were studied. Global CFR, volumes and functions of both ventricles and atria, and presence or absence of myocardial ischemia and infarction were evaluated. Emphysema severity was visually determined on lung CT by Goddard method.</p><p><strong>Result: </strong>Seventy nine (71.0 ± 7.9 years, 75 male) of 210 patients with known or suspected CAD had emphysema on lung CT. Goddard score was significantly correlated with CFR (r = -0.246, P = 0.029), left ventricular end-diastolic volume index (LV EDVI) (r = -0.230, P = 0.041), right ventricular systolic volume index (RV SVI) (r = -0.280, P = 0.012), left atrial (LA) total emptying volume index (r = -0.269, P = 0.017), LA passive emptying volume index (r = -0.309, P = 0.006), LA systolic strain (Es) (r = -0.244, P = 0.030), and LA conduit strain (Ee) (r = -0.285, P = 0.011) in the patients with emphysema. Multiple linear regression analysis revealed LA conduit function was independently associated with emphysema severity as determined by Goddard method (beta = -0.361, P = 0.006).</p><p><strong>Conclusion: </strong>LA conduit function independently associates with emphysema severity in the emphysema patients with known or suspected CAD after adjusting age, sex, smoking, and the CMR indexes including CFR. These findings suggest that impairment of LA function predominantly occurs prior to the reduction of the CFR in the emphysema patients with known or suspected CAD.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10695058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Phase Difference Information to Detect Errors in the Flip Angle Measured with Actual Flip Angle Imaging at 7T.","authors":"Tsuyoshi Matsuda, Yuji Iwadate, Futoshi Mori, Kota Takeda, Makoto Sasaki","doi":"10.2463/mrms.tn.2022-0053","DOIUrl":"10.2463/mrms.tn.2022-0053","url":null,"abstract":"<p><p>Flip angle (FA) measurements using the actual flip angle imaging (AFI) method may induce significant errors in ultrahigh fields. We aimed to develop a method for detecting errors in FA measurements using phase information at 7 tesla. We performed computer simulations to elucidate the relationship between the FA calculation errors and the phase difference between the two AFI source images. We then examined whether a method based on the phase difference could detect FA calculation errors and determine the prescribed nominal FA of the scanner for accurate measurements in phantoms and healthy volunteers. The simulations confirmed that the calculated FA values erroneously decreased when the longitudinal magnetization and phase in one of the source images were inverted. Tests on phantoms and human subjects demonstrated that the phase difference information between the source images with a cut-off of 90° could readily detect FA calculation errors in the AFI method.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40490184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemosiderin Detection inside the Mammillary Bodies Using Quantitative Susceptibility Mapping on Patients with Wernicke-Korsakoff Syndrome.","authors":"Yuri Nakamura, Yasutaka Fushimi, Takuya Hinoda, Satoshi Nakajima, Akihiko Sakata, Sachi Okuchi, Sayo Otani, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Hirotsugu Kawashima, Maiko T Uemura, Yuji Nakamoto","doi":"10.2463/mrms.ici.2022-0109","DOIUrl":"10.2463/mrms.ici.2022-0109","url":null,"abstract":"<p><p>Hemorrhage inside the mammillary bodies (MMBs) is known to be one of the findings of Wernicke encephalopathy. Brain MRI of two patients with Wernicke-Korsakoff syndrome (WKS) demonstrated high susceptibility values representing hemosiderin deposition in MMBs by using quantitative susceptibility mapping (QSM). QSM provided additional information of susceptibility values to susceptibility-weighted imaging in diagnosis of WKS.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10407162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Characteristics of Pelvic High-grade Serous Carcinomas with and without Breast Cancer Gene Variants on MR Imaging.","authors":"Tsukasa Saida, Ayumi Shikama, Kensaku Mori, Toshitaka Ishiguro, Takeo Minaguchi, Toyomi Satoh, Takahito Nakajima","doi":"10.2463/mrms.mp.2022-0061","DOIUrl":"10.2463/mrms.mp.2022-0061","url":null,"abstract":"<p><strong>Purpose: </strong>To compare MRI findings of high-grade serous carcinoma (HGSC) with and without breast cancer (BRCA) gene variants to explore the feasibility of MRI as a genetic predictor.</p><p><strong>Methods: </strong>We retrospectively reviewed MRI data from 16 patients with BRCA variant-positive (11 patients of BRCA1 and 5 patients of BRCA2 variant-positive) and 32 patients with BRCA variant-negative HGSCs and evaluated tumor size, appearance, nature of solid components, apparent diffusion coefficient (ADC) value, time-intensity curve, several dynamic contrast-enhanced curve descriptors, and nature of peritoneal metastasis. Age, primary site, tumor stage, bilaterality, presence of lymph node metastasis, presence of peritoneal metastasis, and tumor markers were also compared between the groups with the Mann-Whitney U and chi-square tests.</p><p><strong>Results: </strong>The mean tumor size of BRCA variant-positive HGSCs was 9.6 cm, and that of variant-negative HGSCs was 6.8 cm, with no significant difference (P = 0.241). No significant difference was found between BRCA variant-positive and negative HGSCs in other evaluated factors, except for age (mean age, 53 years old; range, 32-78 years old for BRCA variant-positive and mean age, 61 years old; range, 44-80 years old for BRCA variant-negative, P = 0.033). Comparing BRCA1 variant-positive and BRCA2 variant-positive HGSCs, BRCA1 variant-positive HGSCs were larger (P = 0.040), had greater Max enhancement (P = 0.013), Area under the curve (P = 0.013), and CA125 (P = 0.038), and had a higher frequency of lymph node metastasis (P = 0.049), with significance.</p><p><strong>Conclusion: </strong>There was no significant difference in the MRI findings between patients with HGSCs with and without BRCA variants. Although studied in small numbers, BRCA1 variant-positive HGSCs were larger and more enhanced than BRCA2 variant-positive HGSCs with higher CA125 and more frequent lymph node metastases, and may represent more aggressive features.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40684419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Arterial and Venous Imaging Using 3D Quantitative Parameter Mapping.","authors":"Tomoki Amemiya, Suguru Yokosawa, Yo Taniguchi, Ryota Sato, Yoshihisa Soutome, Hisaaki Ochi, Toru Shirai","doi":"10.2463/mrms.mp.2021-0170","DOIUrl":"10.2463/mrms.mp.2021-0170","url":null,"abstract":"<p><strong>Purpose: </strong>To increase the number of images that can be acquired in MR examinations using quantitative parameters, we developed a method for obtaining arterial and venous images with mapping of proton density (PD), RF inhomogeneity (B1), longitudinal relaxation time (T1), apparent transverse relaxation time (T2*), and magnetic susceptibility through calculation, all with the same spatial resolution.</p><p><strong>Methods: </strong>The proposed method uses partially RF-spoiled gradient echo sequences to obtain 3D images of a subject with multiple scan parameters. The PD, B1, T1, T2*, and magnetic susceptibility maps are estimated using the quantification method we previously developed. Arterial images are obtained by adding images using optimized weights to emphasize the arteries. A morphology filter is used to obtain venous images from the magnetic susceptibility maps. For evaluation, images obtained from four out of five healthy volunteers were used to optimize the weights used in the arterial-image calculation, and the optimized weights were applied to the images from the fifth volunteer to obtain an arterial image. Arterial images of the five volunteers were calculated using the leave-one-out method, and the contrast between the arterial and background regions defined using the reference time-of-flight (TOF) method was evaluated using the area under the receiver operation characteristic curve (AUC). The contrast between venous and background regions defined by a reference quantitative susceptibility mapping (QSM) method was also evaluated for the venous image.</p><p><strong>Results: </strong>The AUC to discriminate blood vessels and background using the proposed method was 0.905 for the arterial image and 0.920 for the venous image.</p><p><strong>Conclusion: </strong>The results indicate that the arterial images and venous images have high signal intensity at the same region as determined from the reference TOF and QSM methods, demonstrating the possibility of acquiring vasculature images with quantitative parameter mapping through calculation in an integrated manner.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10781149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ex-vivo 1.5T MR Imaging versus CT in Estimating the Size of the Pathologically Invasive Component of Lung Adenocarcinoma Spectrum Lesions.","authors":"Daisuke Yamada, Masaki Matsusako, Daisuke Yoneoka, Katsunori Oikado, Hironori Ninomiya, Taiki Nozaki, Mitsutomi Ishiyama, Akari Makidono, Mizuto Otsuji, Harumi Itoh, Hiroya Ojiri","doi":"10.2463/mrms.mp.2022-0125","DOIUrl":"10.2463/mrms.mp.2022-0125","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to investigate whether ex-vivo MRI enables accurate estimation of the invasive component of lung adenocarcinoma.</p><p><strong>Methods: </strong>We retrospectively reviewed 32 patients with lung adenocarcinoma who underwent lung lobectomy. The specimens underwent MRI at 1.5T. The boundary between the lesion and the normal lung was evaluated on a 5-point scale in each three MRI sequences, and a one-way analysis of variance and post-hoc tests were performed. The invasive component size was measured histopathologically. The maximum diameter of each solid component measured on CT and MR T1-weighted (T1W) images and the maximum size obtained from histopathologic images were compared using the Wilcoxon signed-rank test. Inter-reader agreement was evaluated using intraclass correlation coefficients (ICC).</p><p><strong>Results: </strong>T1W images were determined to be optimal for the delineation of the lesions (P < 0.001). The histopathologic invasive area corresponded to the area where the T1W ex-vivo MR image showed a high signal intensity that was almost equal to the intravascular blood signal. The maximum diameter of the solid component on CT was overestimated compared with the maximum invasive size on histopathology (mean, 153%; P < 0.05), while that on MRI was evaluated mostly accurately without overestimation (mean, 108%; P = 0.48). The interobserver reliability of the measurements using CT and MRI was good (ICC = 0.71 on CT, 0.74 on MRI).</p><p><strong>Conclusion: </strong>Ex-vivo MRI was more accurate than conventional CT in delineating the invasive component of lung adenocarcinoma.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10441899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey of Delivery Outcomes for Employees at MR Imaging Facilities in Japan Based on Information Recorded in the Maternal and Child Health Handbook.","authors":"Sachiko Yamaguchi-Sekino, Noriko Kojimahara","doi":"10.2463/mrms.bc.2022-0080","DOIUrl":"10.2463/mrms.bc.2022-0080","url":null,"abstract":"<p><p>The effect of maternal occupational non-ionizing radiation (NIR) exposure from MRI on premature birth and low birth weight delivery was analyzed based on questionnaire survey (263 employees, 443 births). Although the highest occurrence rates of both outcomes were observed in the group whose NIR exposure occurred only before pregnancy, no statistical significance was detected.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40512787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}