Zachary Shah, Yonatan Urman, Ashwin S. Kumar, Bruno Soares, Kawin Setsompop
{"title":"Accelerating Longitudinal MRI using Prior Informed Latent Posterior Sampling (PIPS)","authors":"Zachary Shah, Yonatan Urman, Ashwin S. Kumar, Bruno Soares, Kawin Setsompop","doi":"10.58530/2025/0934","DOIUrl":"https://doi.org/10.58530/2025/0934","url":null,"abstract":"Motivation: Long scan times persist longitudinal MRI studies, yet lack good reconstruction priors for accelerated parallel imaging. Goal(s): Substantially and scaleably reduce scantime by leveraging prior scans of the same patient in a data-consistent deep learning reconstruction. Approach: Propose Prior Informed Posterior Sampling (PIPS) with latent diffusion. We train such a model on unlabeled image data, eliminating the need for a dataset of either k-space measurements or paired longitudinal scans required of other learning-based methods. Results: Outperform baselines in effectively utilizing prior information without over-biasing prior consistency. Validated on an open-source dataset of healthy patients, as well as several longitudinal cases with clinical differentials. Impact: We propose an unsupervised prior conditioning method to further accelerate MRI for longitudinal studies. Our method is both scalable and generalizable, as it does not require sequential k-space for training and enforces data consistency throughout the reconstruction.","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147916828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>National Conference of Infectious Diseases 14-16 May 2025, Timișoara, România</i>","authors":"Elena - Voichița Lăzureanu","doi":"10.70921/medev.v31i1-supplement.1297","DOIUrl":"https://doi.org/10.70921/medev.v31i1-supplement.1297","url":null,"abstract":"We are pleased to present this Supplement to Volume XXXI, No. 1/2025 of the journal Medicine in Evolution, a special collection of scientific contributions dedicated to current challenges and advances in the field of infectious diseases, immunization, and antimicrobial therapies. This supplement brings together high-impact topics at the forefront of medical research and clinical practice. The thematic focus includes the persistent global challenge of HIV/AIDS, centered around a critical question: Can we stop the pandemic? Other articles explore the real-world difficulties encountered in the treatment of acute and chronic viral hepatitis, addressing both therapeutic barriers and innovative solutions. Vaccination is also prominently featured, with perspectives combining long-term experience and cutting-edge innovation. Furthermore, this supplement covers modern strategies in antibiotic, antiviral, and antifungal therapy, reflecting the ongoing need to combat resistance and improve therapeutic efficacy. A dedicated Varia section provides additional original contributions spanning a wide range of medical disciplines and interests. We gratefully acknowledge the leadership of Prof. Univ. Dr. Voichița Lăzureanu, President of the Conference, whose commitment and expertise have been essential in curating this scientific endeavor. Our sincere appreciation also goes to Prof. Univ. Dr. Adrian Streinu-Cercel, Honorary President, whose remarkable contributions to infectious disease research and public health continue to inspire generations of medical professionals. We hope that this supplement will serve as a valuable resource for researchers, clinicians, and public health specialists, fostering dialogue and advancing knowledge in the pursuit of better health outcomes worldwide","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":"31 1-Supplement","pages":"1-74"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://medicineinevolution.ro/index.php/medev/article/download/1297/1240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel T1 Analysis Method to Address Reduced Measurement Accuracy Due to Irregular Heart Rate Variability in Myocardial T1 Mapping Using Polarity-corrected Inversion Time Preparation.","authors":"Yuta Endo, Sanae Takahashi, Haruna Shibo, Makoto Amanuma, Kuninori Kobayashi, Shigehide Kuhara","doi":"10.2463/mrms.mp.2023-0029","DOIUrl":"10.2463/mrms.mp.2023-0029","url":null,"abstract":"<p><strong>Purpose: </strong>Polarity-corrected inversion time preparation (PCTIP), a myocardial T1 mapping technique, is expected to reduce measurement underestimation in the modified Look-Locker inversion recover method. However, measurement precision is reduced, especially for heart rate variability. We devised an analysis using a recurrence formula to overcome this problem and showed that it improved the measurement accuracy, especially at high heart rates. Therefore, this study aimed to determine the effect of this analysis on the accuracy and precision of T1 measurements for irregular heart rate variability.</p><p><strong>Methods: </strong>A PCTIP scan using a 3T MRI scanner was performed in phantom experiment. We generated the simulated R-waves required for electrocardiogram (ECG)-gated acquisition using a signal generator set to 30 combinations. T1 map was generated using the signal train of the PCTIP images by nonlinear curve fitting using conventional and recurrence formulas. Accuracy against reference T1 and precision of heart rate variability were evaluated. To evaluate the fitting accuracy of both analyses, the relative fitting error was calculated.</p><p><strong>Results: </strong>For the longer T1, the fitting error was larger than the short T1, with the conventional analysis showing 10.1±2.0%. The recurrence formula analysis showed a small fitting error less than 1%, which was consistent for all heart rate variability patterns. In the conventional analysis, the accuracy, especially for longer T1, showed a large underestimation of the measurements and poor linearity. However, in the recurrence formula analysis, the accuracy improved at a long T1, and linearity also improved. The Bland-Altman plot showed that it varied greatly depending on the heart rate variability pattern for the longer T1 in the conventional analysis, whereas the recurrence formula analysis suppressed this variation.</p><p><strong>Conclusion: </strong>T1 analysis of PCTIP using the recurrence formula analysis achieved accurate and precise T1 measurements, even for irregular heart rate variability.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"1-9"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10500239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical and Clinical Evaluation of the Robustness of Open-source Networks for Parallel MR Imaging Reconstruction.","authors":"Naoto Fujita, Suguru Yokosawa, Toru Shirai, Yasuhiko Terada","doi":"10.2463/mrms.mp.2023-0031","DOIUrl":"10.2463/mrms.mp.2023-0031","url":null,"abstract":"<p><strong>Purpose: </strong>Deep neural networks (DNNs) for MRI reconstruction often require large datasets for training. Still, in clinical settings, the domains of datasets are diverse, and how robust DNNs are to domain differences between training and testing datasets has been an open question. Here, we numerically and clinically evaluate the generalization of the reconstruction networks across various domains under clinically practical conditions and provide practical guidance on what points to consider when selecting models for clinical application.</p><p><strong>Methods: </strong>We compare the reconstruction performance between four network models: U-Net, the deep cascade of convolutional neural networks (DC-CNNs), Hybrid Cascade, and variational network (VarNet). We used the public multicoil dataset fastMRI for training and testing and performed a single-domain test, where the domains of the dataset used for training and testing were the same, and cross-domain tests, where the source and target domains were different. We conducted a single-domain test (Experiment 1) and cross-domain tests (Experiments 2-4), focusing on six factors (the number of images, sampling pattern, acceleration factor, noise level, contrast, and anatomical structure) both numerically and clinically.</p><p><strong>Results: </strong>U-Net had lower performance than the three model-based networks and was less robust to domain shifts between training and testing datasets. VarNet had the highest performance and robustness among the three model-based networks, followed by Hybrid Cascade and DC-CNN. Especially, VarNet showed high performance even with a limited number of training images (200 images/10 cases). U-Net was more robust to domain shifts concerning noise level than the other model-based networks. Hybrid Cascade showed slightly better performance and robustness than DC-CNN, except for robustness to noise-level domain shifts. The results of the clinical evaluations generally agreed with the results of the quantitative metrics.</p><p><strong>Conclusion: </strong>In this study, we numerically and clinically evaluated the robustness of the publicly available networks using the multicoil data. Therefore, this study provided practical guidance for clinical applications.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"460-478"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9897830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nonlinear Gradient Field Mapping Using a Spherical Grid Phantom for 3 and 7 Tesla MR Imaging Systems Equipped with High-performance Gradient Coils.","authors":"Ryoichi Kose, Katsumi Kose, Koji Fujimoto, Tomohisa Okada, Daiki Tamada, Utaroh Motosugi","doi":"10.2463/mrms.tn.2023-0063","DOIUrl":"10.2463/mrms.tn.2023-0063","url":null,"abstract":"<p><p>Recent high-performance gradient coils are fabricated mainly at the expense of spatial linearity. In this study, we measured the spatial nonlinearity of the magnetic field generated by the gradient coils of two MRI systems with high-performance gradient coils. The nonlinearity of the gradient fields was measured using 3D gradient echo sequences and a spherical phantom with a built-in lattice structure. The spatial variation of the gradient field was approximated to the 3rd order polynomials. The coefficients of the polynomials were calculated using the steepest descent method. The geometric distortion of the acquired 3D MR images was corrected using the polynomials and compared with the 3D images corrected using the harmonic functions provided by the MRI venders. As a result, it was found that the nonlinearity correction formulae provided by the vendors were insufficient and needed to be verified or corrected using a geometric phantom such as used in this study.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"525-536"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Utility of an Adjusted DWI Lexicon Using Multiple b-values to Evaluate Breast Lesions in Combination with BI-RADS.","authors":"Aika Okazawa, Mami Iima, Masako Kataoka, Ryosuke Okumura, Sachiko Takahara, Tomotaka Noda, Taro Nishi, Takayoshi Ishimori, Yuji Nakamoto","doi":"10.2463/mrms.mp.2022-0056","DOIUrl":"10.2463/mrms.mp.2022-0056","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to investigate the diagnostic feasibility of an adjusted diffusion-weighted imaging (DWI) lexicon using multiple b values to assess breast lesions according to DWI-based breast imaging reporting and data system (BI-RADS).</p><p><strong>Methods: </strong>This Institutional Review Board (IRB)-approved prospective study included 127 patients with suspected breast cancer. Breast MRI was performed using a 3T scanner. Breast DW images were acquired using five b-values of 0, 200, 800, 1000, and 1500 s/mm<sup>2</sup> (5b-value DWI) on 3T MRI. Two readers independently assessed lesion characteristics and normal breast tissue using DWI alone (5b-value DWI and 2b-value DWI with b = 0 and 800 s/mm<sup>2</sup>) according to DWI-based BI-RADS and in combination with the standard dynamic contrast-enhanced images (combined MRI). Interobserver and intermethod agreements were assessed using kappa statistics. The specificity and sensitivity of lesion classification were evaluated.</p><p><strong>Results: </strong>Ninety-five breast lesions (39 malignant and 56 benign) were evaluated. Interobserver agreement for lesion assessment on 5b-value DWI was very good (k ≥ 0.82) for DWI-based BI-RADS categories, lesion type, and mass characteristics; good (k = 0.75) in breast composition; and moderate (k ≥ 0.44) in background parenchymal signal (BPS) and non-mass distribution. Intermethod agreement between assessments performed using either 5b-value DWI or combined MRI was good-to-moderate (k = 0.52-0.67) for lesion type; moderate (k = 0.49-0.59) for DWI-based BI-RADS category and mass characteristics; and fair (k = 0.25-0.40) for mass shape, BPS, and breast composition. The sensitivity and positive predictive values (PPVs) for 5b-value DWI were 79.5%, 84.6% and 60.8%, 61.1% for each reader, respectively; 74.4%, 74.4% and 63.0%, 61.7% for 2b-value DWI; and 97.4%, 97.4% and 73.1%, 76.0% for combined MRI. The specificity and negative predictive values (NPVs) were 64.3%, 62.5% and 81.8%, 85.4% for 5b-value DWI; 69.6%, 67.9% and 79.6%, 79.2% for 2b-value DWI; and 75.0%, 78.6% and 97.7%, 97.8% for combined MRI.</p><p><strong>Conclusion: </strong>Good observer agreement was observed in the 5b-value DWI. The 5b-value DWI based on multiple b-values might have the potential to complement the 2b-value DWI; however, their diagnostic performance tended to be inferior to that of combined MRI for the characterization of breast tumors.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"438-448"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9526055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating T1, T2 Relaxation, and Proton Density in Normal Brain Using Synthetic MRI with Fast Imaging Protocol.","authors":"Zuofeng Zheng, Yawen Liu, Hongxia Yin, Pengling Ren, Tingting Zhang, Jiafei Yang, Zhenchang Wang","doi":"10.2463/mrms.tn.2022-0161","DOIUrl":"10.2463/mrms.tn.2022-0161","url":null,"abstract":"<p><p>Synthetic MRI is being increasingly used for the quantification of brain longitudinal relaxation time (T1), transverse relaxation time (T2), and proton density (PD) values. However, the effect of fast imaging protocols on these quantitative values has not been fully estimated. The purpose of this study was to investigate the effect of fast scan parameters on T1, T2, and PD measured with a multi-dynamic multi-echo (MDME) sequence of normal brain at 3.0T. Thirty-four volunteers were scanned using 3 MDME sequences with different scan times (named Fast, 2 min, 29 sec; Routine, 4 min, 07 sec; and Research, 7 min, 46 sec, respectively). The measured T1, T2, and PD in 18 volumes of interest (VOI) of brain were compared between the 3 sequences using rank sum test, t test, coefficients of variation (CVs) analysis, correlation analysis, and Bland-Altman analysis. We found that even though T1, T2, and PD were significantly different between the 3 sequences in most of the brain regions, the intersequence CVs were relatively low and linear correlation were high. Bland-Altman plots showed that most of the values fall within the 95% prediction limits. We concluded that fast imaging protocols of MDME sequence used in our study can potentially be used for quantitative evaluation of brain tissues. Since changing scan parameters can affect the measured T1, T2, and PD values, it is necessary to use consistent scan parameter for comparing or following up cases quantitatively.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"514-524"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10256637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Versatile MR Elastography Research Tool with a Modified Motion Signal-to-noise Ratio Approach.","authors":"Daiki Ito, Tetsushi Habe, Tomokazu Numano, Shigeo Okuda, Shigeyoshi Soga, Masahiro Jinzaki","doi":"10.2463/mrms.mp.2022-0149","DOIUrl":"10.2463/mrms.mp.2022-0149","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to facilitate research progress in MR elastography (MRE) by providing a versatile and convenient application for MRE reconstruction, namely the MRE research tool (MRE-rTool). It can be used for a series of MRE image analyses, including phase unwrapping, arbitrary bandpass and directional filtering, noise assessment of the wave propagation image (motion SNR), and reconstruction of the elastogram in both 2D and 3D MRE acquisitions. To reinforce the versatility of MRE-rTool, the conventional method of motion SNR was modified into a new method that reflects the effects of image filtering.</p><p><strong>Methods: </strong>MRE tests of the phantom and liver were performed using different estimation algorithms for stiffness value (algebraic inversion of the differential equation [AIDE], local frequency estimation [LFE] in MRE-rTool, and multimodel direct inversion [MMDI] in clinical reconstruction) and acquiring dimensions (2D and 3D acquisitions). This study also tested the accuracy of masking low SNR regions using modified and conventional motion SNR under various mechanical vibration powers.</p><p><strong>Results: </strong>The stiffness values estimated using AIDE/LFE in MRE-rTool were comparable to that of MMDI (phantom, 3.71 ± 0.74, 3.60 ± 0.32, and 3.60 ± 0.54 kPa in AIDE, LFE, and MMDI; liver, 2.26 ± 0.31, 2.74 ± 0.16, and 2.21 ± 0.26 kPa in AIDE, LFE, and MMDI). The stiffness value in 3D acquisition was independent of the direction of the motion-encoding gradient and was more accurate than that of 2D acquisition. The masking of low SNR regions using the modified motion SNR worked better than that in the conventional motion SNR for each vibration power, especially when using a directional filter.</p><p><strong>Conclusion: </strong>The performance of MRE-rTool on test data reached the level required in clinical MRE studies. MRE-rTool has the potential to facilitate MRE research, contribute to the future development of MRE, and has been freely released online.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"417-427"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9644589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blockage of CSF Outflow in Rats after Deep Cervical Lymph Node Ligation Observed Using Gd-based MR Imaging.","authors":"Naoya Kinota, Hiroyuki Kameda, Bai Xiawei, Takaaki Fujii, Daisuke Kato, Bunya Takahashi, Ryo Morita, Daisuke Abo, Ryusei Majima, Hiroshi Ishii, Kazuyuki Minowa, Kohsuke Kudo","doi":"10.2463/mrms.mp.2023-0023","DOIUrl":"10.2463/mrms.mp.2023-0023","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether deep cervical lymph node (DCLN) ligation alters intracranial cerebrospinal fluid (CSF) tracer dynamics and outflow using a rat model with intrathecal dynamic contrast-enhanced (DCE) MRI.</p><p><strong>Methods: </strong>Six bilateral DCLN-ligated and six sham-operated rats were subjected to DCE MRI with Gd-BTDO3A, and dynamic T1-weighted images were acquired. ROIs were collected from the CSF at the C1 level (CSF_C1), CSF between the olfactory bulbs (CSF_OB), CSF at the pituitary recess (CSF_PitR), and CSF at the pineal recess (CSF_PinR), upper nasal turbinate (UNT), olfactory bulbs, cerebrum, and the jugular region. Time-intensity curves were evaluated, and the maximum slope, peak timing, peak signal ratio, and elimination half-life for the four CSF ROIs and UNT were calculated and compared.</p><p><strong>Results: </strong>Delayed tracer arrival in the rostral CSF space and the nasal cavity with tracer retention in the ventral CSF space were observed in the ligation group. The maximum slopes were smaller in the ligation group at UNT (sham: 0.075 ± 0.0061, ligation: 0.044 ± 0.0086/min, P = 0.011). A significant difference was not detected in peak timings. The peak signal ratio values were lower in the ligation group at UNT (sham: 2.12 ± 0.19, ligation: 1.72 ± 0.11, P = 0.011). The elimination half-life was delayed in the ligation group at CSF_C1 (sham: 30.5 ± 2.70, ligation: 44.4 ± 12.6 min, P = 0.043), CSF_OB (sham: 30.2 ± 2.67, ligation: 44.8 ± 7.47 min, P = 0.021), and CSF_PitR (sham: 30.2 ± 2.49, ligation: 41.3 ± 7.57 min, P = 0.021).</p><p><strong>Conclusion: </strong>The DCLN ligation in rats blocked CSF outflow into the nasal cavity and caused CSF retention.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"449-459"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Slab and Pencil Beam Labeling in Spin-labeled MR Imaging for Pancreatic Juice Flow Visualization.","authors":"Hideki Hoshi, Reiji Sugita, Yoshio Machida","doi":"10.2463/mrms.tn.2022-0132","DOIUrl":"10.2463/mrms.tn.2022-0132","url":null,"abstract":"<p><p>The usefulness of a highly targeted pencil beam (PB) label was compared with the commonly used slab label for direct visualization of pancreaticobiliary reflux using the time-spatial labeling inversion pulse (time-SLIP) technique. Signal profiles of flow phantom images obtained with a 1.5T MRI were analyzed. Both labels had similar labeling capabilities, but the edge characteristics of the PB label were blunt. Next, sixty-eight patients were classified into two groups according to the angle of the pancreaticobiliary ducts, and the displacement of the pancreatic ducts in respiratory fluctuation was measured. The results were approximately 7 mm in both groups. The blunt edge characteristics of the PB label suggest that it is robust to respiratory fluctuations. The overall labeling ability of the PB is comparable to that of the slab. In the larger angle of pancreaticobiliary ducts, the PB label may be able to label the pancreatic duct more selectively.</p>","PeriodicalId":18119,"journal":{"name":"Magnetic Resonance in Medical Sciences","volume":" ","pages":"502-513"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11447465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9671398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}