Optimal Protocol for Contrast-enhanced Free-running 5D Whole-heart Coronary MR Angiography at 3T.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-04-01 Epub Date: 2023-01-20 DOI:10.2463/mrms.tn.2022-0086

Masaki Ishida, Jérôme Yerly, Haruno Ito, Masafumi Takafuji, Shiro Nakamori, Shinichi Takase, Yoshito Ichiba, Yoshiaki Komori, Kaoru Dohi, Davide Piccini, Jessica A M Bastiaansen, Matthias Stuber, Hajime Sakuma

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Abstract

Free-running 5D whole-heart coronary MR angiography (MRA) is gaining in popularity because it reduces scanning complexity by removing the need for specific slice orientations, respiratory gating, or cardiac triggering. At 3T, a gradient echo (GRE) sequence is preferred in combination with contrast injection. However, neither the injection scheme of the gadolinium (Gd) contrast medium, the choice of the RF excitation angle, nor the dedicated image reconstruction parameters have been established for 3T GRE free-running 5D whole-heart coronary MRA. In this study, a Gd injection scheme, RF excitation angles of lipid-insensitive binominal off-resonance RF excitation (LIBRE) pulse for valid fat suppression and continuous data acquisition, and compressed-sensing reconstruction regularization parameters were optimized for contrast-enhanced free-running 5D whole-heart coronary MRA using a GRE sequence at 3T. Using this optimized protocol, contrast-enhanced free-running 5D whole-heart coronary MRA using a GRE sequence is feasible with good image quality at 3T.

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3T 下对比度增强自由运行 5D 全心冠状动脉磁共振血管造影的最佳方案。

自由运行的 5D 全心冠状动脉磁共振血管成像（MRA）无需特定的切片方向、呼吸门控或心脏触发，从而降低了扫描的复杂性，因此越来越受欢迎。在 3T 下，梯度回波（GRE）序列与造影剂注射相结合是首选。然而，3T GRE 自由运行 5D 全心冠状动脉 MRA 的钆（Gd）造影剂注射方案、射频激发角的选择和专用图像重建参数都尚未确定。本研究优化了钆注射方案、用于有效脂肪抑制和连续数据采集的对脂质不敏感的双全离共振射频激发（LIBRE）脉冲的射频激发角度以及压缩传感重建正则化参数，用于在 3T 下使用 GRE 序列进行对比度增强的自由运行 5D 全心冠状动脉 MRA。使用该优化方案，在 3T 下使用 GRE 序列进行对比度增强自由运行 5D 全心冠状动脉 MRA 可获得良好的图像质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464