Korean Journal of Radiology最新文献

{"title":"Frequently Asked Questions on Imaging in Chimeric Antigen Receptor T-Cell Therapy Clinical Trials.","authors":"Sang Eun Won, Eun Sung Lee, Chong Hyun Suh, Sinae Kim, Hyo Jung Park, Kyung Won Kim, Jeffrey P Guenette","doi":"10.3348/kjr.2024.1126","DOIUrl":"https://doi.org/10.3348/kjr.2024.1126","url":null,"abstract":"<p><p>Clinical trials for chimeric antigen receptor (CAR) T-cell therapy are in the early stages but are expected to progress alongside new treatment approaches. This suggests that imaging will play an important role in monitoring disease progression, treatment response, and treatment-related side effects. There are, however, challenges that remain unresolved, regarding imaging in CAR T-cell therapy. We herein discuss the role of imaging, focusing on how tumor response evaluation varies according to cancer type and target antigens in CAR T-cell therapy. CAR T-cell therapy often produces rapid and significant responses, and imaging is vital for identifying side effects such as cytokine release syndrome and neurotoxicity. Radiologists should be aware of drug mechanisms, response assessments, and associated toxicities to effectively support these therapies. Additionally, this article highlights the importance of the Lugano criteria, which is essential for standardized assessment of treatment response, particularly in lymphoma therapies, and also explores other factors influencing imaging-based evaluation, including emerging methodologies and their potential to improve the accuracy and consistency of response assessments.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"471-484"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Deep Learning-Based Reconstruction on the Quality of Accelerated Contrast-Enhanced Neck MRI.","authors":"Minkook Seo, Kook-Jin Ahn, Hyun-Soo Lee, Marcel Dominik Nickel, Jinhee Jang, Yeon Jong Huh, Ilah Shin, Ji Young Lee, Bum-Soo Kim","doi":"10.3348/kjr.2024.1059","DOIUrl":"https://doi.org/10.3348/kjr.2024.1059","url":null,"abstract":"<p><strong>Objective: </strong>To compare the quality of deep learning-reconstructed turbo spin-echo (DL-TSE) and conventionally interpolated turbo spin-echo (Conv-TSE) techniques in contrast-enhanced MRI of the neck.</p><p><strong>Materials and methods: </strong>Contrast-enhanced T1-weighted DL-TSE and Conv-TSE images were acquired using 3T scanners from 106 patients. DL-TSE employed a closed-source, 'work-in-progress' (WIP No. 1062, iTSE, version 10; Siemens Healthineers) algorithm for interpolation and denoising to achieve the same in-plane resolution (axial: 0.26 × 0.26 mm²; coronal: 0.29 × 0.29 mm²) while reducing scan times by 15.9% and 52.6% for axial and coronal scans, respectively. The full width at half maximum (FWHM) and percent signal ghosting were measured using stationary and flow phantom scans, respectively. In patient images, non-uniformity (NU), contrast-to-noise ratio (CNR), and regional mucosal FWHM were evaluated. Two neuroradiologists visually rated the patient images for overall quality, sharpness, regional mucosal conspicuity, artifacts, and lesions using a 5-point Likert scale.</p><p><strong>Results: </strong>FWHM in the stationary phantom scan was consistently sharper in DL-TSE. The percent signal ghosting outside the flow phantom was lower in DL-TSE (0.06% vs. 0.14%) but higher within the phantom (8.92% vs. 1.75%) compared to Conv-TSE. In patient scans, DL-TSE showed non-inferior NU and higher CNR. Regional mucosal FWHM was significantly better in DL-TSE, particularly in the oropharynx (coronal: 1.08 ± 0.31 vs. 1.52 ± 0.46 mm) and hypopharynx (coronal: 1.26 ± 0.35 vs. 1.91 ± 0.56 mm) (both <i>P</i> < 0.001). DL-TSE demonstrated higher overall image quality (axial: 4.61 ± 0.49 vs. 3.32 ± 0.54) and sharpness (axial: 4.40 ± 0.56 vs. 3.11 ± 0.53) (both <i>P</i> < 0.001). In addition, mucosal conspicuity was improved, especially in the oropharynx (axial: 4.41 ± 0.67 vs. 3.40 ± 0.69) and hypopharynx (axial: 4.45 ± 0.58 vs. 3.58 ± 0.63) (both <i>P</i> < 0.001). Extracorporeal ghost artifacts were reduced in DL-TSE (axial: 4.32 ± 0.60 vs. 3.90 ± 0.71, <i>P</i> < 0.001) but artifacts overlapping anatomical structures were slightly more pronounced (axial: 3.78 ± 0.74 vs. 3.95 ± 0.72, <i>P</i> < 0.001). Lesions were detected with higher confidence in DL-TSE.</p><p><strong>Conclusion: </strong>DL-based reconstruction applied to accelerated neck MRI improves overall image quality, sharpness, mucosal conspicuity in motion-prone regions, and lesion detection confidence. Despite more pronounced ghost artifacts overlapping anatomical structures, DL-TSE enables substantial scan time reduction while enhancing diagnostic performance.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"446-445"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased CT Attenuation of Pericolic Adipose Tissue as a Noninvasive Marker of Disease Severity in Ulcerative Colitis.","authors":"Jun Lu, Hui Xu, Jing Zheng, Tianxin Cheng, Xinjun Han, Yuxin Wang, Xuxu Meng, Xiaoyang Li, Jiahui Jiang, Xue Dong, Xijie Zhang, Zhenchang Wang, Zhenghan Yang, Lixue Xu","doi":"10.3348/kjr.2024.0857","DOIUrl":"https://doi.org/10.3348/kjr.2024.0857","url":null,"abstract":"<p><strong>Objective: </strong>Accurate evaluation of inflammation severity in ulcerative colitis (UC) can guide treatment strategy selection. The potential value of the pericolic fat attenuation index (FAI) on CT as an indicator of disease severity remains unknown. This study aimed to assess the diagnostic accuracy of pericolic FAI in predicting UC severity.</p><p><strong>Materials and methods: </strong>This retrospective study enrolled 148 patients (mean age 48 years; 87 males). The fat attenuation on CT was measured in four different locations: the mesocolic vascular side (MS) and opposite side of MS (OMS) around the most severe bowel lesion, the retroperitoneal space (RS), and the subcutaneous area. The fat attenuation indices (FAI_MS, FAI_OMS, and FAI_RS) were calculated as the fat attenuation measured in MS, OMS, and RS, respectively, minus that of the subcutaneous area, and were obtained in the non-enhanced, arterial, and delayed phases. Correlations between the FAI and UC Endoscopic Index of Severity (UCEIS) were assessed using Spearman's correlation. Predictors of severe UC (UCEIS ≥7) were selected by univariable analysis. The performance of FAI in predicting severe UC was evaluated using the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>The FAI_MS and FAI_OMS scores were significantly higher than FAI_RS in three phases (all <i>P</i> < 0.001). The FAI_MS and FAI_OMS scores moderately correlated with the UCEIS score (<i>r</i> = 0.474-0.649 among the three phases). Additionally, FAI_MS and FAI_OMS identified severe UC, with AUC varying from 0.77 to 0.85.</p><p><strong>Conclusion: </strong>Increased CT attenuation of pericolic adipose tissue could serve as a noninvasive marker for evaluating UC severity. FAI_MS and FAI_OMS of three phases showed similar prediction accuracies for severe UC identification.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"411-421"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric MRI to Predict Gleason Score Upgrading and Downgrading at Radical Prostatectomy Compared to Presurgical Biopsy.","authors":"Jiahui Zhang, Lili Xu, Gumuyang Zhang, Daming Zhang, Xiaoxiao Zhang, Xin Bai, Li Chen, Qianyu Peng, Zhengyu Jin, Hao Sun","doi":"10.3348/kjr.2024.1008","DOIUrl":"10.3348/kjr.2024.1008","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the value of multiparametric MRI (mpMRI) in predicting Gleason score (GS) upgrading and downgrading in radical prostatectomy (RP) compared with presurgical biopsy.</p><p><strong>Materials and methods: </strong>Clinical and mpMRI data were retrospectively collected from 219 patients with prostate disease between January 2015 and December 2021. All patients underwent systematic prostate biopsy followed by RP. MpMRI included conventional diffusion-weighted and dynamic contrast-enhanced imaging. Multivariable logistic regression analysis was performed to analyze the factors associated with GS upgrading and downgrading after RP. Receiver operating characteristic curve analysis was used to estimate the area under the curve (AUC) to indicate the performance of the multivariable logistic regression models in predicting GS upgrade and downgrade after RP.</p><p><strong>Results: </strong>The GS after RP was upgraded, downgraded, and unchanged in 92, 43, and 84 patients, respectively. The AUCs of the clinical (percentage of positive biopsy cores [PBCs], time from biopsy to RP) and mpMRI models (prostate cancer [PCa] location, Prostate Imaging Reporting and Data System [PI-RADS] v2.1 score) for predicting GS upgrading after RP were 0.714 and 0.749, respectively. The AUC of the combined diagnostic model (age, percentage of PBCs, tPSA, PCa location, and PI-RADS v2.1 score) was 0.816, which was larger than that of the clinical factors alone (<i>P</i> < 0.001). The AUCs of the clinical (age, percentage of PBCs, ratio of free/total PSA [F/T]) and mpMRI models (PCa diameter, PCa location, and PI-RADS v2.1 score) for predicting GS downgrading after RP were 0.749 and 0.835, respectively. The AUC of the combined diagnostic model (age, percentage of PBCs, F/T, PCa diameter, PCa location, and PI-RADS v2.1 score) was 0.883, which was larger than that of the clinical factors alone (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Combining clinical factors and mpMRI findings can predict GS upgrade and downgrade after RP more accurately than using clinical factors alone.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"422-434"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women and the Road to Radiology Leadership: An Asian Perspective.","authors":"Evelyn Lai Ming Ho","doi":"10.3348/kjr.2025.0140","DOIUrl":"https://doi.org/10.3348/kjr.2025.0140","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"397-399"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of Multiparameter MRI-Guided Percutaneous Biopsy for Central Lung Lesions With Atelectasis.","authors":"Peipei Li, Chengli Li, Yujun Xu, Xiangmeng He, Roberto Blanco Sequeiros, Ming Liu","doi":"10.3348/kjr.2024.0818","DOIUrl":"https://doi.org/10.3348/kjr.2024.0818","url":null,"abstract":"<p><strong>Objective: </strong>To prospectively evaluate the feasibility, accuracy, and safety of multiparameter MRI-guided percutaneous biopsy using a 1T open MRI scanner for evaluating suspicious centrally located lung lesions with associated post-obstructive atelectasis.</p><p><strong>Materials and methods: </strong>In this single-center study, MRI-guided percutaneous coaxial cutting biopsy was performed for 107 suspicious central lung lesions with associated post-obstructive atelectasis in 107 patients between July 2015 and December 2020. A fast T2-weighted imaging (T2WI)-turbo spin echo (TSE) sequence and an enhanced fast T1-weighted imaging (T1WI)-TSE sequence were used to identify, localize, and biopsy lung lesions, and diffusion-weighted imaging (DWI) was used as a supplementary sequence for identifying the lesion location. The final diagnosis was confirmed by surgical histopathology or clinical follow-up for a minimum of 24 months. The sensitivity, specificity, and accuracy for diagnosing lung malignancies were calculated, and the complications were recorded for each case.</p><p><strong>Results: </strong>Using multiparameter MRI, central lung lesions could be clearly distinguished from post-obstructive atelectasis in 96 patients (89.7%). The sensitivity, specificity, and accuracy of MRI-guided percutaneous biopsy for diagnosing lung malignancy was 97.0% (98/101), 100% (6/6), and 97.2% (104/107), respectively. Self-limited hemoptysis occurred in three patients. Pneumothorax occurred in five patients, of which none required pleural drainage. No serious procedure-related complications were observed.</p><p><strong>Conclusion: </strong>As a technology that does not involve ionizing radiation, multiparameter MRI-guided percutaneous coaxial cutting biopsy is a safe and accurate diagnostic technique for evaluating centrally located lung lesions associated with post-obstructive atelectasis.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"498-507"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025 Korean Society of Abdominal Radiology Recommendations on Gallbladder Polyps and Gallbladder Wall Thickening Warrant Further Investigation and Clarification.","authors":"Chen Lin, Liang Zhu","doi":"10.3348/kjr.2025.0201","DOIUrl":"10.3348/kjr.2025.0201","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"514-515"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Recommendations for Gallbladder Polyps and Gallbladder Wall Thickening Between KSAR and WFUMB Guidelines.","authors":"Rui Cheng, Yi Dong","doi":"10.3348/kjr.2025.0186","DOIUrl":"10.3348/kjr.2025.0186","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"508-510"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-Parameter MRI for Evaluating Glymphatic Impairment and White-Matter Abnormalities and Discriminating Refractory Epilepsy in Children.","authors":"Lu Qiu, Miaoyan Wang, Surui Liu, Bo Peng, Ying Hua, Jianbiao Wang, Xiaoyue Hu, Anqi Qiu, Yakang Dai, Haoxiang Jiang","doi":"10.3348/kjr.2024.0718","DOIUrl":"https://doi.org/10.3348/kjr.2024.0718","url":null,"abstract":"<p><strong>Objective: </strong>To explore glymphatic impairment in pediatric refractory epilepsy (RE) using multi-parameter magnetic resonance imaging (MRI), assess its relationship with white-matter (WM) abnormalities and clinical indicators, and preliminarily evaluate the performance of multi-parameter MRI in discriminating RE from drug-sensitive epilepsy (DSE).</p><p><strong>Materials and methods: </strong>We retrospectively included 70 patients with DSE (mean age, 9.7 ± 3.5 years; male:female, 37:33) and 26 patients with RE (9.0 ± 2.9 years; male:female, 12:14). The diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index as well as fractional anisotropy (FA), mean diffusivity (MD), and nodal efficiency values were measured and compared between patients with RE and DSE. With sex and age as covariables, differences in the FA and MD values were analyzed using tract-based spatial statistics, and nodal efficiency was analyzed using a linear model. Pearson's partial correlation was analyzed. Receiver operating characteristic (ROC) curves were used to evaluate the discrimination performance of the MRI-based machine-learning models through five-fold cross-validation.</p><p><strong>Results: </strong>In the RE group, FA decreased and MD increased in comparison with the corresponding values in the DSE group, and these differences mainly involved the callosum, right and left corona radiata, inferior and superior longitudinal fasciculus, and posterior thalamic radiation (threshold-free cluster enhancement, <i>P</i> < 0.05). The RE group also showed reduced nodal efficiency, which mainly involved the limbic system, default mode network, and visual network (false discovery rate, <i>P</i> < 0.05), and significantly lower DTI-ALPS index (F = 2.0, <i>P</i> = 0.049). The DTI-ALPS index was positively correlated with FA (0.25 ≤ <i>r</i> ≤ 0.32) and nodal efficiency (0.22 ≤ <i>r</i> ≤ 0.37), and was negatively correlated with the MD (-0.24 ≤ <i>r</i> ≤ -0.34) and seizure frequency (<i>r</i> = -0.47). A machine-learning model combining DTI-ALPS, FA, MD, and nodal efficiency achieved a cross-validated ROC curve area of 0.83 (sensitivity, 78.2%; specificity, 84.8%).</p><p><strong>Conclusion: </strong>Pediatric patients with RE showed impaired glymphatic function in comparison with patients with DSE, which was correlated with WM abnormalities and seizure frequency. Multi-parameter MRI may be feasible for distinguishing RE from DSE.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"485-497"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Efficacy of Radiofrequency Ablation for Superficial Parotid Pleomorphic Adenoma.","authors":"Chih-Ying Lee, Wei-Che Lin, Sheng-Dean Luo, Pi-Ling Chiang, An-Ni Lin, Cheng-Kang Wang, Chun-Yuan Chao","doi":"10.3348/kjr.2024.0909","DOIUrl":"https://doi.org/10.3348/kjr.2024.0909","url":null,"abstract":"<p><strong>Objective: </strong>To retrospectively compare the safety and efficacy of ultrasound-guided radiofrequency ablation (RFA) with parotidectomy for superficial pleomorphic adenoma (PA).</p><p><strong>Materials and methods: </strong>From March 2022 to October 2023, 88 patients diagnosed with superficial parotid PA underwent either RFA (n = 12; mean age, 47.1 years) or parotidectomy (n = 76; mean age, 47.8 years). Patients in the RFA group were matched to those in the surgery group in a 1:1 ratio using propensity scores based on age, sex, tumor volume, diameter, location, and comorbidities. Ultrasound characteristics, cosmetic scores (0-4), numerical rating scale scores (0-10), and complications were assessed before the procedures and at 1-, 3-, and 6-month follow-ups. Outcomes were compared between baseline and follow-up in the RFA group and between the RFA and surgery groups.</p><p><strong>Results: </strong>In the RFA group, significant reductions in tumor volume were observed between baseline (median, 2.02 cm³) and the 1-month follow-up (median, 1.21 cm³; <i>P</i> = 0.015), between the 1-month and 3-month follow-ups (median, 0.53 cm³; <i>P</i> = 0.002), and between the 3- and 6-month follow-ups (median, 0.23 cm³; <i>P</i> = 0.003). The volume reduction ratios at 1, 3, and 6 months were 39.7%, 79.9%, and 88.0%, respectively. The cosmetic score was significantly lower at 3- and 6-month follow-up compared to baseline (median 1 and 1 vs. 4, <i>P</i> = 0.04). The numerical rating scale scores did not differ significantly from baseline throughout follow-up. In the propensity score-matched analysis (12 patients per group), RFA was associated with a shorter median procedure time (61.5 vs. 253.3 minutes; <i>P</i> < 0.001), shorter hospital stay (0 vs. 4 days; <i>P</i> < 0.001), and lower cost (1859.9 vs. 3512.4 USD; <i>P</i> < 0.001) than parotidectomy, with no significant difference in overall complication rates (33.3% [4/12] vs. 41.7% [5/12]; <i>P</i> = 1.000).</p><p><strong>Conclusion: </strong>RFA may be a safe and effective alternative to surgery for superficial parotid PA, offering a shorter median procedure time, shorter hospital stay, and lower costs.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"460-470"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}