Yong Jun Jung, Eun Sun Choi, Dong Hwan Kim, Sang Hyun Choi, Seung Soo Lee, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
{"title":"Prognostic Implications of CT- and MRI-Based LI-RADS Category M Features in Intrahepatic Cholangiocarcinoma: An Intraindividual Comparison.","authors":"Yong Jun Jung, Eun Sun Choi, Dong Hwan Kim, Sang Hyun Choi, Seung Soo Lee, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin","doi":"10.3348/kjr.2026.0652","DOIUrl":"10.3348/kjr.2026.0652","url":null,"abstract":"<p><strong>Objective: </strong>Liver Imaging Reporting and Data System category M (LR-M) is associated with a poor prognosis in intrahepatic cholangiocarcinoma (iCCA). However, the prognostic value of individual LR-M features across imaging modalities remains unclear. We aimed to determine, through intraindividual comparisons, whether the prognostic value of individual LR-M features differs between CT and MRI in patients with iCCA at risk for hepatocellular carcinoma.</p><p><strong>Materials and methods: </strong>This retrospective study included consecutive patients with cirrhosis or chronic hepatitis B who underwent curative-intent resection for iCCA and preoperative multiphasic CT and MRI between 2010 and 2019. CT and MRI images were reviewed in separate sessions ≥4 weeks apart. Cox proportional hazards regression analyses with and without adjustment for LI-RADS categorization (non-LR-M vs. single-modality LR-M or dual-modality LR-M) were performed to evaluate the associations of CT- and MRI-based targetoid and non-targetoid LR-M features and other variables with recurrence-free survival (RFS) and overall survival (OS).</p><p><strong>Results: </strong>A cohort of 122 patients (mean age, 57.9 ± 10.4 years) was included. MRI demonstrated significantly higher frequencies than CT for targetoid (84.4% vs. 73.8%, <i>P</i> = 0.007) and non-targetoid features (43.4% vs. 20.5%, <i>P</i> < 0.001), resulting in a higher rate of LR-M categorization (90.2% vs. 81.1%, <i>P</i> = 0.003). In the multivariable analysis, CT-based targetoid features (hazard ratio [HR] = 2.31 for RFS, <i>P</i> = 0.010; HR = 1.85 for OS, <i>P</i> = 0.043) and MRI-based non-targetoid features (HR = 2.15 for RFS, <i>P</i> = 0.005; HR = 2.09 for OS, <i>P</i> = 0.008) were independently associated with poorer survival. After adjustment for LI-RADS categorization, MRI-based non-targetoid features remained independently associated with poorer RFS (HR = 1.76, <i>P</i> = 0.041) and OS (HR = 1.79, <i>P</i> = 0.038). Dual-modality LR-M designation was independently associated with poorer RFS (HR = 8.02, <i>P</i> = 0.042).</p><p><strong>Conclusion: </strong>The prognostic implications of LR-M features in iCCA vary by imaging modality and feature type. CT-based targetoid and MRI-based non-targetoid features were associated with poorer survival, and the associations between MRI-based non-targetoid features and survival remained significant after adjustment for LI-RADS categorization.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"948-960"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consideration of Statin Therapy in the Interpretation of Artificial Intelligence-Derived Coronary Artery Calcium Density.","authors":"Xue Liu","doi":"10.3348/kjr.2026.0980","DOIUrl":"10.3348/kjr.2026.0980","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"1023-1024"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Na Young Kim, Dong Jin Im, Yoo Jin Hong, Ji Won Lee, Chul Hwan Park, Ji Ye Jung, Jin Gu Lee, Hye-Jeong Lee
{"title":"Sequential Changes in Right Ventricular Strain During the Development of Pulmonary Hypertension Assessed With Magnetic Resonance Feature Tracking: An Animal Study.","authors":"Na Young Kim, Dong Jin Im, Yoo Jin Hong, Ji Won Lee, Chul Hwan Park, Ji Ye Jung, Jin Gu Lee, Hye-Jeong Lee","doi":"10.3348/kjr.2026.0774","DOIUrl":"10.3348/kjr.2026.0774","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the sequential changes in right ventricular (RV) strain and histological vascular remodeling and their correlations during pulmonary hypertension (PH) development in a rat model by using cardiac magnetic resonance (CMR)-feature tracking (FT).</p><p><strong>Materials and methods: </strong>Separate cohorts of six-week-old male Wistar rats (10 per group) were allocated to a baseline group, PH induction groups assessed at 1, 2, 3, or 4 weeks after monocrotaline injection, and vehicle-injected control groups assessed at 2 and 4 weeks. Each rat underwent a single magnetic resonance imaging (MRI) examination and was subsequently euthanized for histological analysis. Cine images were acquired using a 9.4T MRI scanner, and strain was analyzed using the FT technique. Histological analysis was used to quantify pulmonary arterial wall thickness percentage (PA %WT) and RV collagen density. Overall group differences were analyzed using the Kruskal-Wallis test, which was followed by the Mann-Whitney U test with Bonferroni correction for pairwise comparisons with the baseline group. Correlations between the variables were assessed using Spearman's correlation coefficients.</p><p><strong>Results: </strong>All CMR-derived RV parameters showed significant differences across the baseline and PH induction groups (all <i>P</i> < 0.001). RV free wall longitudinal strain (RVFWLS) showed the earliest impairment at 2 weeks, with a progressive decline thereafter. The RV free wall circumferential strain (RVFWCS) and RV ejection fraction were reduced beginning at 3 weeks, whereas the RV end-diastolic volume index increased significantly only at 4 weeks. The PA %WT increased progressively from week 2, whereas the RV collagen density did not change significantly. RVFWLS and RVFWCS showed strong positive correlations with PA %WT (<i>r</i> = 0.885 and <i>r</i> = 0.757, respectively; both <i>P</i> < 0.001), which were primarily driven by parallel changes across the post-induction time points. The control groups showed no significant temporal changes in the CMR or histological measurements.</p><p><strong>Conclusion: </strong>In this preclinical model of PH, staged CMR and histological assessments demonstrated sequential RV remodeling in parallel with PA remodeling, with RVFWLS impairment preceding overt RV dysfunction and enlargement.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"936-947"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Stratification or Disease Staging? Re-Evaluating the Evidence Base for Neoplastic Gallbladder Polyp Management.","authors":"Huiting Liu, Xue Liu","doi":"10.3348/kjr.2026.0900","DOIUrl":"10.3348/kjr.2026.0900","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"1016-1017"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sung Il Hwang, Hunjong Lim, Kyong Joon Lee, Hak Jong Lee, Hyungwoo Ahn, Yoojin Nam, Masahiro Jinzaki
{"title":"Is Vibe Coding a 'Fire of Prometheus' for Non-Developer Clinicians, Especially Clinical Radiologists?","authors":"Sung Il Hwang, Hunjong Lim, Kyong Joon Lee, Hak Jong Lee, Hyungwoo Ahn, Yoojin Nam, Masahiro Jinzaki","doi":"10.3348/kjr.2026.0914","DOIUrl":"10.3348/kjr.2026.0914","url":null,"abstract":"<p><p>Vibe coding is a workflow in which users describe the desired software behavior in natural language, following which large language models (LLMs) generate the code. It is increasingly being used by non-developer clinicians without any formal programming training to create tools that support the clinical workflow. This development is both timely and consequential for radiology, one of the specialties both most exposed to artificial intelligence (AI)-driven automation and best positioned to adopt it owing to its longstanding engagement with imaging AI, digital infrastructure, and information system workflows. Therefore, radiologists may become not merely passive AI users, but also clinical workflow orchestrators. This opportunity is illustrated by a structured prostate magnetic resonance imaging reporting tool, vibe-coded by a non-developer radiologist in approximately four hours, with an institution-based voluntary, radiologist-led coding community. This investigation highlighted four cautions: erosion of domain expertise, risks to security and patient data, absence of peer feedback, and uncoordinated proliferation of tools. A minimum safeguard set for clinician-built tools was proposed. As previously framed, LLMs represent a \"fire of Prometheus\" for non-native English-speaking researchers. Similarly, vibe coding may warm and burn radiologists equally, with its impact determined less by technology than by how responsibly the specialty adopts it.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"27 10","pages":"929-935"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2026 Korean Association for the Study of the Liver Guidelines for Chronic Hepatitis B Management: A Radiological Perspective.","authors":"Hyo Jung Park, So Yeon Kim, Bo Hyun Kim","doi":"10.3348/kjr.2026.1224","DOIUrl":"10.3348/kjr.2026.1224","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"27 10","pages":"925-928"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to \"Risk Stratification or Disease Staging? Re-Evaluating the Evidence Base for Neoplastic Gallbladder Polyp Management\".","authors":"Jeong Hee Yoon, Sunyoung Lee, Hyun-Soo Zhang","doi":"10.3348/kjr.2026.1104","DOIUrl":"10.3348/kjr.2026.1104","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"1018-1020"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woojin Yi, Hyo Jin Lee, Nari Kim, Seongwon Na, Mihyun Kim, Hyobin Shim, Hyunmin Yoo, Kyung Won Kim
{"title":"Decentralized Clinical Trials in Oncology-A Radiological Perspective.","authors":"Woojin Yi, Hyo Jin Lee, Nari Kim, Seongwon Na, Mihyun Kim, Hyobin Shim, Hyunmin Yoo, Kyung Won Kim","doi":"10.3348/kjr.2026.0865","DOIUrl":"10.3348/kjr.2026.0865","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"27 10","pages":"1005-1009"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabella Andrea Bolaños Bermúdez, José David Cardona Ortegón, Sara París Zorro, Javier Andrés Romero Enciso
{"title":"Breast Imaging Reporting and Data System v2025 Auditing: Ensuring Outcome Ascertainment for More Reliable Global Benchmarking.","authors":"Isabella Andrea Bolaños Bermúdez, José David Cardona Ortegón, Sara París Zorro, Javier Andrés Romero Enciso","doi":"10.3348/kjr.2026.1168","DOIUrl":"10.3348/kjr.2026.1168","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"1021-1022"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nerve Injury During Thyroid Radiofrequency Ablation: Mechanisms, Prevention, and Practical Management.","authors":"Hunjong Lim, Jung Hwan Baek","doi":"10.3348/kjr.2026.0878","DOIUrl":"10.3348/kjr.2026.0878","url":null,"abstract":"<p><p>Voice change is an uncommon but clinically important complication of thyroid radiofrequency ablation (RFA), because it may indicate injury to the recurrent laryngeal nerve or, less commonly, the vagus nerve. Early recognition and appropriate intervention are important, because neural dysfunction may remain reversible before the occurrence of irreversible structural nerve injury. Thermal nerve injury during thyroid RFA is not always a single instantaneous event. Rather, it may involve direct thermal exposure of the nerves, leading to acute endoneurial or perineural edema, microvascular compromise, and delayed inflammation or fibrosis. Therefore, a practical approach to the management of voice changes during thyroid RFA should emphasize prevention, frequent intraprocedural voice assessment, immediate cessation of ablation, and prompt bolus injection of cold 5% dextrose in water. After adequate cooling, local dexamethasone injections and a short course of oral corticosteroid therapy may be considered. In conclusion, a mechanism-based framework may improve operator preparedness and reduce the risk of persistent nerve dysfunction.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"27 10","pages":"973-981"},"PeriodicalIF":6.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}