Journal of the Indian Chemical Society最新文献

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Zinc vanadate nanoparticle: An innovative electrochemical sensor synthesized via green fuel for the detection of ascorbic acid and its other applications
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-03 DOI: 10.1016/j.jics.2025.101607
H. Anantharama , J.R. Naveen Kumar , M. Rohit , Divya R. Basavannavar , B.M. Praveen , Asad Syed , R. Harini , G. Nagaraju , Bharath K. Devendra
{"title":"Zinc vanadate nanoparticle: An innovative electrochemical sensor synthesized via green fuel for the detection of ascorbic acid and its other applications","authors":"H. Anantharama ,&nbsp;J.R. Naveen Kumar ,&nbsp;M. Rohit ,&nbsp;Divya R. Basavannavar ,&nbsp;B.M. Praveen ,&nbsp;Asad Syed ,&nbsp;R. Harini ,&nbsp;G. Nagaraju ,&nbsp;Bharath K. Devendra","doi":"10.1016/j.jics.2025.101607","DOIUrl":"10.1016/j.jics.2025.101607","url":null,"abstract":"<div><div>Zinc vanadate (Zn<sub>4</sub>V<sub>2</sub>O<sub>9</sub>) nanoparticles (NPs) have been effectively produced at 600 °C using the solution combustion technique. The as-synthesized Zn<sub>4</sub>V<sub>2</sub>O<sub>9</sub> NPs were further examined using a variety of methods, including photoluminescence (PL), Fourier transform infrared spectroscopy (FTIR), ultraviolet–visible spectroscopy (UV–Vis), and X-ray diffraction (XRD), to look at the surface morphological characteristics of a material or sample as well as its optical and crystal structural characteristics. Additionally, the synthesized Nps is employed in various processes including photocatalytic dye degradation of Rose Bengal dye and latent finger printing.Zn<sub>4</sub>V<sub>2</sub>O<sub>9</sub> NPs were discovered to have a crystal size of 45.97 nm, and the XRD pattern indicates that the synthesized NPs had a monoclinic crystallite structure. Scanning electron microscopy (SEM) is used to identify the shape of NPs. <span>l</span>-Ascorbic acid (LAA) presence is detected using the produced NPs. This study involves dropcasting of NPs and electrode modification. The electrode is utilized for additional research after being left overnight to dry.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 3","pages":"Article 101607"},"PeriodicalIF":3.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrothermal synthesis of Co, Cu dual doped CeO2 based nanoceramic electrolyte material and evaluation of its physical, electrochemical and dielectric properties for LTSOFC
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-03 DOI: 10.1016/j.jics.2025.101611
Kaliappan Tamilselvan, Arputharaj Samson Nesaraj
{"title":"Hydrothermal synthesis of Co, Cu dual doped CeO2 based nanoceramic electrolyte material and evaluation of its physical, electrochemical and dielectric properties for LTSOFC","authors":"Kaliappan Tamilselvan,&nbsp;Arputharaj Samson Nesaraj","doi":"10.1016/j.jics.2025.101611","DOIUrl":"10.1016/j.jics.2025.101611","url":null,"abstract":"<div><div>Co, Cu dual doped ceria nanoceramic electrolyte material with the composition of Ce<sub>0.50</sub>Co<sub>0.25</sub>Cu<sub>0.25</sub>O<sub>2-δ</sub> (CCCO) was synthesized by a simple hydrothermal route using stoichiometric amount of metal nitrates with sodium hydroxide precipitant. The properties of the prepared nano-ceramic particles were systematically evaluated by TGA, XRD, FTIR, EDAX, SEM and TEM. The XRD data confirmed the formation of FCC structure. FTIR data revealed the existence of M − O band in the sample. SEM and TEM photographs showed the manifestation of nano-grains in the sample. Presence of appropriate elements with atomic weight % was confirmed by the EDAX data. The circular sintered CCCO disk components were subjected to impedance and dielectric studies from room temperature to 540 <sup>o</sup>C in air. The oxide ion conductivity for the electrolyte was enhanced systematically from room temperature and attained a maximum value of 6.4583x10<sup>-4</sup> Scm<sup>-1</sup> at 540 <sup>o</sup>C. The activation energy was found to be 0.40 eV at the optimum temperature (540 <sup>o</sup>C). The dielectric constant of the sintered specimen was slowly enhanced with raise in temperature at varied frequency ranges. From the results, it was found that the proposed composition may be a better choice as an alternate electrolyte material for low temperature solid oxide fuel cell (LTSOFC) application.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 3","pages":"Article 101611"},"PeriodicalIF":3.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143324155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced antimicrobial activity: Synthesis and structural analysis of Co(II) and Cu(II) coordinated metal complexes with azo-thiol NS bidentate ligands
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-03 DOI: 10.1016/j.jics.2025.101610
Amro Ahmed Taha , Mai M. Khalaf , Hany M. Abd El-Lateef , Mohamed Gouda , Antar A. Abdelhamid , Mohamed Abdelbaset , Anas Alfarsi , Aly Abdou
{"title":"Enhanced antimicrobial activity: Synthesis and structural analysis of Co(II) and Cu(II) coordinated metal complexes with azo-thiol NS bidentate ligands","authors":"Amro Ahmed Taha ,&nbsp;Mai M. Khalaf ,&nbsp;Hany M. Abd El-Lateef ,&nbsp;Mohamed Gouda ,&nbsp;Antar A. Abdelhamid ,&nbsp;Mohamed Abdelbaset ,&nbsp;Anas Alfarsi ,&nbsp;Aly Abdou","doi":"10.1016/j.jics.2025.101610","DOIUrl":"10.1016/j.jics.2025.101610","url":null,"abstract":"<div><div>In this study, we successfully designed and synthesized two novel metal complexes, Cobalt(II) (CoSDN) and Copper(II) (CuSDN), derived from the 4-[(2-sulfanylphenyl)diazenyl]naphthalen-1-ol (SDN) ligand. A suite of advanced techniques, including UV–Vis spectroscopy, mass spectrometry, infrared (IR) spectroscopy, elemental analysis, conductivity and magnetic measurements, and thermogravimetric analysis (TGA), was employed for comprehensive characterization. The IR spectroscopy results confirmed that the SDN ligand coordinates to metal ions through the nitrogen atom of its azo (-N<img>N-) linkage and the sulfur atom of the thiol (-SH) group. Thermal analysis (TGA) revealed additional insights into the binding environment, particularly the involvement of water molecules within the complexes' structures. Furthermore, the antimicrobial potential of the SDN ligand, as well as its CoSDN and CuSDN complexes, was rigorously evaluated through <em>in vitro</em> testing against a spectrum of pathogenic bacteria and fungi. Notably, the CoSDN and CuSDN complexes demonstrated significantly enhanced antimicrobial activity compared to the free SDN ligand, effectively inhibiting specific microorganisms. These findings underline the exceptional promise of these metal complexes for future biomedical applications, suggesting their potential as innovative therapeutic agents to combat microbial threats.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 3","pages":"Article 101610"},"PeriodicalIF":3.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical enrichment of polyvinyl alcohol films by neodymium oxide and multi-walled carbon nanotube for optical applications
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-02 DOI: 10.1016/j.jics.2025.101614
T.S. Soliman , S. Abouelazm , Mahmoud M. Hessien
{"title":"Optical enrichment of polyvinyl alcohol films by neodymium oxide and multi-walled carbon nanotube for optical applications","authors":"T.S. Soliman ,&nbsp;S. Abouelazm ,&nbsp;Mahmoud M. Hessien","doi":"10.1016/j.jics.2025.101614","DOIUrl":"10.1016/j.jics.2025.101614","url":null,"abstract":"<div><div>The current topic addresses the structure and optical features of the polyvinyl alcohol (PVA) film after adding two different components. Four composite matrices were prepared via the casting process: neat PVA film, PVA film blended with multi-walled carbon nanotube (MWCNT), and PVA-MWCNT blend film reinforced with 2 % and 4 % Nd<sub>2</sub>O<sub>3</sub>. The composite films were characterized by various techniques, including X-ray diffractometer (XRD), Fourier-transform infrared (FTIR), optical microscope, and ultraviolet–visible spectrophotometer. The XRD and FTIR investigation revealed that adding MWCNT and Nd<sub>2</sub>O<sub>3</sub> alters the phase structure of the PVA film, and the crystallinity decreases. The PVA film's absorbance increases by adding MWCNT, besides the decrease of the transmittance by adding Nd<sub>2</sub>O<sub>3</sub> nanoparticles in the UV region. The bandgap energy of the PVA film decreased from 5.44 eV to 4.18 eV. In addition, doping the PVA-MWCNT blend with Nd<sub>2</sub>O<sub>3</sub> nanoparticles declines the bandgap energy to about 3.27 eV and 3.06 eV by adding 2 % and 4 % Nd<sub>2</sub>O<sub>3</sub>, respectively. Linear and nonlinear optical parameters like refractive index (linear and nonlinear), metallization criteria, and optical susceptibility were enhanced by adding MWCNT and Nd<sub>2</sub>O<sub>3</sub> nanoparticles. The PVA-MWCNT-Nd<sub>2</sub>O<sub>3</sub> composite film with enhanced optical parameters is promising for optical and biomedical applications.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 3","pages":"Article 101614"},"PeriodicalIF":3.2,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, characterization, and in vitro antimicrobial studies of new Mn(II), Fe(III) and Ni(III) complexes based on 4-[(2 sulfanylphenyl)diazenyl]naphthalen-1-ol ligand
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-01 DOI: 10.1016/j.jics.2025.101601
Mai M. Khalaf , Hany M. Abd El-Lateef , Mohamed Gouda , Amro Ahmed Taha , Antar A. Abdelhamid , Mohamed Abdelbaset , Abdulelah H. Alsulami , Aly Abdou
{"title":"Synthesis, characterization, and in vitro antimicrobial studies of new Mn(II), Fe(III) and Ni(III) complexes based on 4-[(2 sulfanylphenyl)diazenyl]naphthalen-1-ol ligand","authors":"Mai M. Khalaf ,&nbsp;Hany M. Abd El-Lateef ,&nbsp;Mohamed Gouda ,&nbsp;Amro Ahmed Taha ,&nbsp;Antar A. Abdelhamid ,&nbsp;Mohamed Abdelbaset ,&nbsp;Abdulelah H. Alsulami ,&nbsp;Aly Abdou","doi":"10.1016/j.jics.2025.101601","DOIUrl":"10.1016/j.jics.2025.101601","url":null,"abstract":"<div><div>This study successfully synthesized three novel metal complexes: MnSDN, FeSDN, and NiSDN, and thoroughly characterized them using UV spectroscopy, infrared (IR) spectroscopy, mass spectrometry, elemental analysis, conductivity and magnetic measurements, as well as thermogravimetric analysis (TGA). The IR spectral analysis indicates that the azo ligand, 4-[(2-sulfanylphenyl)diazenyl]naphthalen-1-ol (SDN), coordinates with metal ions via its nitrogen atoms in the azo (-N<img>N-) bond and sulfur atoms in the thiol (-SH) moiety. Thermal analysis (TGA) further revealed the quantity &amp; binding sites of H<sub>2</sub>O molecules within the complex compounds. Additionally, <em>in vitro</em> assessments of the antibacterial &amp; antifungal activities of the ligand and its metal complex components were conducted against various pathogenic bacteria &amp; fungi. Particularly, the metal complex products revelation significantly greater inhibitory effects on certain microorganisms compared to the uncoordinated ligand. Among the tested compounds, the metal complexes demonstrated superior biological activity, whereas the free ligand showed the least efficacy. These promising results suggest that these metal complexes possess potential physiological effects and may serve as valuable candidates for various medical applications in the future.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 2","pages":"Article 101601"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveils the macromolecular structure of high-sulfur Indian coal for hydrogen production
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-01 DOI: 10.1016/j.jics.2024.101558
Tonkeswar Das , Debashis Sarmah , Gaurav Jhaa , Bhargab Das , Preetom Kishore Nath , Abhishek Borborah , Mousumi Bora
{"title":"Unveils the macromolecular structure of high-sulfur Indian coal for hydrogen production","authors":"Tonkeswar Das ,&nbsp;Debashis Sarmah ,&nbsp;Gaurav Jhaa ,&nbsp;Bhargab Das ,&nbsp;Preetom Kishore Nath ,&nbsp;Abhishek Borborah ,&nbsp;Mousumi Bora","doi":"10.1016/j.jics.2024.101558","DOIUrl":"10.1016/j.jics.2024.101558","url":null,"abstract":"<div><div>In this study, for the first time, we reported the molecular structure of Cenozoic coal from the northeastern region of India, which is a rare form of coal and known as low quality due to high sulfur, non-coking nature, low ash fusion temperature, and high volatile matter. These findings are crucial for efficiently utilizing this coal in hydrogen production. The analysis revealed that the coal has a high aromaticity (77.33 %) and aliphatic structure (22.66 %), with a molecular formula of C<sub>179</sub>H<sub>140</sub>O<sub>32</sub>N<sub>3</sub>S<sub>4</sub>. The bridge to peripheral aromatic carbon ratio is 0.657, indicating the prevalence of tetracyclic pyrene as the primary aromatic skeleton, along with auxiliary structural units such as pentacene, chrysene, anthracene, naphthalene, and benzene. The coal contains oxygen-containing functional groups and structures such as pyridine, pyrrolic, thiophenol, and thiophene. The study also included creating and optimizing 2D and 3D coal macromolecular structures through molecular dynamics simulations and global hybrid density functional theory. Additionally, the thermal properties and model free kinetic study of the coal were investigated, showing an ignition temperature of 416 °C and an apparent activation energy of 171.36 kJ mol<sup>−1</sup>, providing insight into its degradation behaviour at different temperatures.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 2","pages":"Article 101558"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication and characterization of Ca-BTC metal-organic framework/polylactic acid/gelatine porous composite as a bone tissue engineering scaffold
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-01 DOI: 10.1016/j.jics.2025.101590
Zeinab Ansari-Asl , Tahereh Sedaghat , Elham Hoveizi , Soghra Nikpour
{"title":"Fabrication and characterization of Ca-BTC metal-organic framework/polylactic acid/gelatine porous composite as a bone tissue engineering scaffold","authors":"Zeinab Ansari-Asl ,&nbsp;Tahereh Sedaghat ,&nbsp;Elham Hoveizi ,&nbsp;Soghra Nikpour","doi":"10.1016/j.jics.2025.101590","DOIUrl":"10.1016/j.jics.2025.101590","url":null,"abstract":"<div><div>The main aim of tissue engineering (TE) is replacement or regeneration of organs or tissues that are damaged by injuries or diseases. In this study, a novel porous composite scaffold, Ca-BTC MOF/PLA/Gelatine, was prepared by incorporating a Ca-based metal-organic framework (Ca-BTC MOF) into polylactic acid (PLA) and gelatine mixture. PLA/Gelatine scaffold was also fabricated as a control. The as-obtained materials were studied by various techniques such as FT-IR (Fourier-transform infrared), XRD (X-ray diffraction), SEM (scanning electron microscope), and EDS (energy-dispersive spectroscopy) elemental mapping. The EDS elemental mapping and SEM images confirmed the homogeneous dispersion of the Ca-BTC MOF particles into the porous scaffold. Additionally, SEM images confirmed the interconnected porous morphology of the as-prepared scaffold. The obtained scaffold was evaluated in terms of structural and biocompatibility properties, as well as its ability to promote bone development. <em>In vivo</em> studies confirmed that the Ca-BTC MOF/PLA/Gelatine scaffold has superior bone formation capability compared to the PLA/Gelatine group. Additionally, this scaffold exhibited enhanced bone formation compared to the control. These findings suggest that the Ca-BTC MOF/PLA/Gelatine scaffold is a promising material for bone regeneration, with potential applications in orthopedics.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 2","pages":"Article 101590"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive analysis of adsorption dynamics of textile dyes on date seed carbon (DSC)
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-01 DOI: 10.1016/j.jics.2025.101576
Tejas Boralkar, Satish Mane, Manohar Sawant, Vishwanath Dalvi
{"title":"Predictive analysis of adsorption dynamics of textile dyes on date seed carbon (DSC)","authors":"Tejas Boralkar,&nbsp;Satish Mane,&nbsp;Manohar Sawant,&nbsp;Vishwanath Dalvi","doi":"10.1016/j.jics.2025.101576","DOIUrl":"10.1016/j.jics.2025.101576","url":null,"abstract":"<div><div>This research investigates the efficacy of date seed carbon (DSC), an eco-friendly and cost-effective adsorbent derived from agricultural waste, for the removal of textile dyes from wastewater. Textile effluents, which carry high pollutant loads, pose significant environmental threats. Batch adsorption experiments were conducted under varying conditions of dye concentration (50–150 mg/L), stirring speed (100–800 rpm), and adsorbent weight (0.5–1.5 g). The adsorption data were analysed using Freundlich and Langmuir isotherm models, with the maximum adsorption capacity observed at 72.5 mg/g for Reactive Green dye. The predictive model developed in this study determined a diffusion coefficient of <span><math><mrow><mn>1.2</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>−</mo><mn>9</mn></mrow></msup></mrow></math></span> cm<sup>2</sup>/s and a mass transfer coefficient of <span><math><mrow><mn>3.5</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>−</mo><mn>4</mn></mrow></msup></mrow></math></span> cm/s under optimal conditions. The experimental results demonstrated dye removal efficiencies exceeding 90 % for concentrations up to 100 mg/L. These findings establish DSC as a promising candidate for efficient, sustainable, and industrial-scale textile effluent treatment. The presented study highlights the potential of DSC to advance eco-friendly wastewater management solutions and reduce environmental impacts.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 2","pages":"Article 101576"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nano Fe2O3/Ag/CeO2 catalyzed solvent free synthesis of 1,8 – di oxo octa hydro xanthene derivatives as potential anti-cancer agents
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-01 DOI: 10.1016/j.jics.2025.101600
Mohammad Kazem Mohammadi , Nasim Kakesh
{"title":"Nano Fe2O3/Ag/CeO2 catalyzed solvent free synthesis of 1,8 – di oxo octa hydro xanthene derivatives as potential anti-cancer agents","authors":"Mohammad Kazem Mohammadi ,&nbsp;Nasim Kakesh","doi":"10.1016/j.jics.2025.101600","DOIUrl":"10.1016/j.jics.2025.101600","url":null,"abstract":"<div><div>Biologically active 1,8–dioxo-octa-hydro-xanthene derivatives were synthesized using Fe<sub>2</sub>O<sub>3</sub>/Ag/CeO<sub>2</sub> nanoparticles as a catalyst under solvent-free conditions. synthesized xanthene derivatives have Excellent yields of products and simple work-up are attractive features of this green protocol. The findings indicate that the catalyst can be used for a minimum of five cycles with only a slight decline in catalytic activity. Furthermore, the catalyst's reusability was also examined in the case of benzaldehyde at 90 °C under solvent-free conditions. Fe<sub>2</sub>O<sub>3</sub>/Ag/CeO<sub>2</sub> nanoparticles were thoroughly analyzed using XRD, FESEM, and UV techniques. Various substituted xanthenes were prepared and tested for activity against HeLa, SKOV-3, LS-180, MCF7, and Raji cell lines and cultures. The results of the cytotoxic study indicated that the compounds exhibited weak to moderate activity. The reactivity order of halogen substitution appeared to be F &gt; Cl &gt; Br. 3a and 3b exhibited moderate activity against cell lines. The exist of an electron-withdrawing group to the opposite aromatic ring of dihydroxyxanthene derivatives increased the anticancer activity, while the electron-donating group had the opposite effect.</div><div>Furthermore, compound 3f with fluorine substitution demonstrated higher activity, highlighting the significance of this site for the cytotoxic activity of these compounds.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 2","pages":"Article 101600"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surface modified CaO nanoparticles with CMC/D-carvone for enhanced anticancer, antimicrobial and antioxidant activities
IF 3.2 4区 化学
Journal of the Indian Chemical Society Pub Date : 2025-02-01 DOI: 10.1016/j.jics.2025.101586
Mickymaray Suresh , Abdulaziz S. Alothaim , Faleh A. Alfaleh , Noorah Alsowayeh , Kaviya Suresh , Indumathi Thangavelu , Palanisamy Arulselvan
{"title":"Surface modified CaO nanoparticles with CMC/D-carvone for enhanced anticancer, antimicrobial and antioxidant activities","authors":"Mickymaray Suresh ,&nbsp;Abdulaziz S. Alothaim ,&nbsp;Faleh A. Alfaleh ,&nbsp;Noorah Alsowayeh ,&nbsp;Kaviya Suresh ,&nbsp;Indumathi Thangavelu ,&nbsp;Palanisamy Arulselvan","doi":"10.1016/j.jics.2025.101586","DOIUrl":"10.1016/j.jics.2025.101586","url":null,"abstract":"<div><div>The rising prevalence of antimicrobial resistance and the continued challenge to cancer therapy are in desperate need of developing innovative therapeutic strategies. In this regard, the present research work focuses on the development of CaO NPs and CaO-CMC-Dcar nanocomposites for enhanced antimicrobial and anti-cancer activities. CaO nanoparticles were synthesized by facile one pot chemical approach and eventually functionalized with CMC and D-carvone biomolecules. XRD analysis revealed that the crystallite size for CaO and CaO-CMC-Dcar nanoparticles was found to be 21.18 nm and 17.02 nm respectively. The band gap values obtained for CaO and CaO-CMC-Dcar nanoparticles were 4.44 eV, and 4.25 eV respectively. The CaO-CMC-Dcar nanoparticles show absorption maxima at 292 nm, slightly red-shifted from bare CaO nanoparticles. HRTEM and SEM analysis revealed that the prepared samples were roughly spherical and agglomerated in nature. Antimicrobial activity was evaluated against methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) and <em>Candida albicans</em>. The zone of inhibition (ZOI) for CaO-CMC-Dcar nanoparticles against MRSA and <em>C. albicans</em> was 20.1 ± 0.3 mm and 21.1 ± 0.2 mm, respectively, significantly higher than that of pure CaO nanoparticles (14.1 ± 0.2 mm and 13.2 ± 0.1 mm) and comparable to standard anti-bacterial streptomycin and antifungal fluconazole discs. Anticancer activity was assessed via MTT assay against MOLT-4 blood cancer cells, where the IC<sub>50</sub> values for CaO and CaO-CMC-Dcar nanoparticles were 22.6 μg/mL and 21.54 μg/mL, respectively. Additionally, CaO-CMC-Dcar nanoparticles exhibited enhanced antioxidant activity (80 %) compared to CaO (70 %) at 20 μg/mL, with performance comparable to that of Vitamin C. Experimental results revealed that the CaO-CMC-Dcar nanoparticles exhibited superior biological activity compared to pure CaO nanoparticles.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 2","pages":"Article 101586"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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