Journal of the Indian Chemical Society最新文献

Biodiesel synthesis from composite oil utilizing banana peel (Musa paradisiaca) derived catalyst and process parameter optimization using particle swarm method 利用香蕉皮衍生催化剂从复合油中合成生物柴油，并采用粒子群法优化工艺参数

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-13 DOI: 10.1016/j.jics.2025.101664

S. Balamurugan , B.S. Manoj Prabhakar , Smita S. Kulkarni , P.S. Kalos , Ganesh Dongre , C. Karthikeyan

{"title":"Biodiesel synthesis from composite oil utilizing banana peel (Musa paradisiaca) derived catalyst and process parameter optimization using particle swarm method","authors":"S. Balamurugan , B.S. Manoj Prabhakar , Smita S. Kulkarni , P.S. Kalos , Ganesh Dongre , C. Karthikeyan","doi":"10.1016/j.jics.2025.101664","DOIUrl":"10.1016/j.jics.2025.101664","url":null,"abstract":"<div><div>This study explores the production of biodiesel from a blend of Fresh Neem Oil (FNO) and Used Cooking Oil (UCO) using banana peel-derived biomass as a novel catalyst. The novelty of this work lies in the utilization of banana peel waste as an efficient and sustainable catalyst for transesterification, combined with the optimization of process parameters using Particle Swarm Optimization (PSO). The high saturated fatty acid content in UCO, which negatively impacts fuel properties, is counterbalanced by the unsaturated fatty acids in neem oil, improving viscosity and cold flow characteristics. The transesterification process was optimized using Particle Swarm Optimization (PSO), achieving an optimal biodiesel yield of 94.12 % under conditions of 64.35 °C reaction temperature, 14.96:1 methanol-to-composite oil molar ratio, and 3.43 wt% banana peel catalyst concentration. Experimental results closely aligned with PSO predictions, demonstrating the effectiveness of this method. The banana peel catalyst, characterized through XRD, SEM, and EDX, showed high surface area and porosity, with potassium and aluminium compounds enhancing catalytic activity. This research highlights the potential of banana peel-derived catalysts and PSO for improving biodiesel production efficiency, offering a sustainable approach for cleaner fuel generation.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101664"},"PeriodicalIF":3.2,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zinc oxide nano-flowers synthesized via a hydrothermal approach for electrochemical performance as a supercapacitor electrode

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-12 DOI: 10.1016/j.jics.2025.101667

Manisha Yadav, Sanju Choudhari, Pradeep Kumar, Pura Ram

引用次数: 0

Synthesis, structural analysis, and antimicrobial properties of (E)-2-((4-fluorobenzylidene) amino) phenol: A combined experimental and computational study

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-07 DOI: 10.1016/j.jics.2025.101659

Natarajan Elangovan , Natarajan Arumugam , Rohith Ramasamy , Madhappan Santhamoorthy , Rajadurai Vijay Solomon , Seong Cheol Kim , Elyor Berdimurodov

{"title":"Synthesis, structural analysis, and antimicrobial properties of (E)-2-((4-fluorobenzylidene) amino) phenol: A combined experimental and computational study","authors":"Natarajan Elangovan , Natarajan Arumugam , Rohith Ramasamy , Madhappan Santhamoorthy , Rajadurai Vijay Solomon , Seong Cheol Kim , Elyor Berdimurodov","doi":"10.1016/j.jics.2025.101659","DOIUrl":"10.1016/j.jics.2025.101659","url":null,"abstract":"<div><div>Synthetic organic chemistry plays a pivotal role in developing various active compounds with significant therapeutic potential, including Schiff base and its derivatives, which are renowned for their excellent biological properties. This research investigates the synthesis of (E)-2-((4-fluorobenzylidene)amino)phenol (4F2AM) and detailed characterization using various instrumental analyses such as Fourier-transform infrared (FTIR), nuclear magnetic resonance (NMR), ultraviolet–visible (UV–vis), fluorescence spectroscopy, and cyclic voltammetry. The antimicrobial efficiency (antibacterial and antifungal) of the synthesized 4F2AM compound is evaluated both in experimental and computation techniques. A brief density functional theory (DFT) analysis has been performed to understand the structural and physicochemical properties, to validate the <sup>1</sup>H and <sup>13</sup>C NMR chemical shifts, absorption spectra, NBO, FMO analysis, thermodynamic characteristics, and dipole moments, a brief density functional theory (DFT) analysis has been performed to understand the structural and physicochemical properties of the synthesized 4F2AM compound. Computational results demonstrate exceptional concordance with experimental data, such as FTIR, <sup>1</sup>H and <sup>13</sup>C NMR and UV-vi absorption analysis. The synthesized 4F2AM compound showed significant antibacterial efficacy, against the gram-positive (<em>S. aureus</em>), gram-negative (<em>E. coli</em>), and fungus (<em>C. albicans</em>). The antibacterial properties of the 4F2AM compounds are further investigated through molecular docking and molecular dynamics simulations, to understand their biochemical interactions. This study highlights the potential of the synthesized 4F2AM compound that may be applied in biological fields.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101659"},"PeriodicalIF":3.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorescent polymer nanoparticles for targeted drug delivery and synergistic osteosarcoma therapy

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-07 DOI: 10.1016/j.jics.2025.101660

Yunfei Lin, Bing Wang

{"title":"Fluorescent polymer nanoparticles for targeted drug delivery and synergistic osteosarcoma therapy","authors":"Yunfei Lin, Bing Wang","doi":"10.1016/j.jics.2025.101660","DOIUrl":"10.1016/j.jics.2025.101660","url":null,"abstract":"<div><div><strong>Osteosarcoma (OS)</strong> is a malignant bone tumor that predominantly affects adolescents, with symptoms including localized pain and swelling. <strong>DKK1</strong>, an antagonist of the Wnt signaling pathway, plays a pivotal role in tumor progression. This study presents a novel fluorescent nanocarrier (<strong>PLA-PEG-RhB</strong>) designed for the targeted delivery and controlled release of a therapeutic combination of <strong>compound 1</strong> and <strong>doxorubicin (DOX)</strong> (CP1@1@DOX). The <strong>PLA-PEG-RhB</strong> carrier, composed of rhodamine B, PLA, and PEG, enhances drug bioavailability and targeting while enabling real-time fluorescence tracking. The synergistic effect of compound 1 and DOX within the nanocarrier significantly inhibits osteosarcoma cell proliferation and reduces tumor growth, minimizing toxicity to healthy cells. In vitro, <strong>PLA-PEG-RhB@CP1@</strong>1<strong>@DOX</strong> suppressed osteosarcoma cell proliferation by regulating <strong>DKK1</strong> expression and blocking key tumor progression pathways. This study highlights the potential of fluorescent nanomedicine combined with targeted chemotherapy for osteosarcoma treatment.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101660"},"PeriodicalIF":3.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aloe barbadensis miller-based metallic composites for photocatalytic degradation of reactive and cationic dyes and antimicrobial applications

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-06 DOI: 10.1016/j.jics.2025.101654

Remsha Shakeel , Amina Khan , Haq Nawaz Bhatti , Urooj Kamran

{"title":"Aloe barbadensis miller-based metallic composites for photocatalytic degradation of reactive and cationic dyes and antimicrobial applications","authors":"Remsha Shakeel , Amina Khan , Haq Nawaz Bhatti , Urooj Kamran","doi":"10.1016/j.jics.2025.101654","DOIUrl":"10.1016/j.jics.2025.101654","url":null,"abstract":"<div><div>Due to the synergistic effect of the two metals, bimetallic nanoparticles have attracted a lot of attention by boosting their properties as compared to monometallic nanoparticles. Herein, for the first time, bimetallic copper-chromium (Cu–Cr@BMNPs) nanoparticles using Aloe Vera extract (as a capping and reducing agent) were prepared via a hydrothermal approach. The prepared nanoparticles capped with organic moieties and antibacterial activity were employed in wastewater treatment. The calculated z-average size was 200–250 nm, which proved the formation of particles in the nano-range, while a point of zero charge was attained at pH 8.2. The results of band gap energy revealed that Cu–Cr@BMNPs have less energy band gap than monometallic nanoparticles. Digital images of Scanning electron microscopy clearly illustrate irregular and porous surfaces of synthesized particles, while purity of the sample was confirmed through X-ray diffraction spectrum. Synthesized Cu–Cr@BMNPs were used to degrade Reactive Black (RB) and Malachite Green (MG) dyes. The maximum degradation of RB was 85 % at pH 3, catalyst dose of 15 mg, dye concentration of 25 ppm, and exposure time of 60 min. For MG, the maximum degradation of 97 % was observed at pH 8, catalyst dose 20 mg, dye concentration 25 ppm, and time 60 min. Among different kinetic models, the Behnajady-Modirshahla-Ghanbery model was best fitted to the experimental data. Prepared BMNPs showed promising inhibition in the growth of two tested strains <em>E. coli</em> and <em>Staph aureus</em> with a zone of 8 mm. Therefore, Cu–Cr@BMNPs were found to be a promising tool for photocatalytic degradation of dyes as well as antibacterial agents.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101654"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative UV derivative spectrophotometric method for simultaneous quantification of sulfadimethoxine and metronidazole

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-06 DOI: 10.1016/j.jics.2025.101655

Larissa F. dos Santos , Lucas R.M. de Andrade , Teófilo F.M. Cardoso , Karen B.B. Caminha , Debora S. Pires , Erika P. Machado , Patrícia Severino , Marcos S. do Amaral , Eliana B. Souto , Najla M. Kassab

{"title":"Innovative UV derivative spectrophotometric method for simultaneous quantification of sulfadimethoxine and metronidazole","authors":"Larissa F. dos Santos , Lucas R.M. de Andrade , Teófilo F.M. Cardoso , Karen B.B. Caminha , Debora S. Pires , Erika P. Machado , Patrícia Severino , Marcos S. do Amaral , Eliana B. Souto , Najla M. Kassab","doi":"10.1016/j.jics.2025.101655","DOIUrl":"10.1016/j.jics.2025.101655","url":null,"abstract":"<div><div>This study developed and validated an analytical method based on derivative spectrophotometry for the simultaneous determination of sulfadimethoxine (SDM) and metronidazole (MTZ) in veterinary medicines, without the need for prior separation of the drugs. The method employed acetonitrile PA as the solvent at room temperature (25 ± 2 °C). MTZ was quantified using zero-order spectrophotometry at 320 nm, while SDM was determined using first-order spectrum at 266 nm, applying the zero-crossing technique. Analytical validation of the developed methods demonstrated robust results, with a correlation coefficient (r) > 0.990 in the concentration range of 3.0–21.0 μg mL<sup>−1</sup>, satisfactory limits of detection (MTZ: 0.21 μg mL<sup>−1</sup>; SDM: 0.17 μg mL<sup>−1</sup>) and quantification (MTZ: 0.63 μg mL<sup>−1</sup>; SDM: 0.51 μg mL<sup>−1</sup>), precision (relative standard deviation (RSD) < 1.9) and accuracy (recovery of 98.0–102.0 %). With operational simplicity and low cost, the developed method can be adopted for the routine analysis and quality control of medicines with a fix dose combination of these two drugs.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101655"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectroscopic, quantum computational investigation, light harvesting effect, In silco biological evaluations and molecular docking of novel pyrazole derivative - A potential anti-cancer agent

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-04 DOI: 10.1016/j.jics.2025.101657

P. Manikandan , M. Kumar , S. Kaleeswaran , S. Chithra , P. Swarnamughi , Mohammad Nikpassand , Jayavelu Udaya Prakash

{"title":"Spectroscopic, quantum computational investigation, light harvesting effect, In silco biological evaluations and molecular docking of novel pyrazole derivative - A potential anti-cancer agent","authors":"P. Manikandan , M. Kumar , S. Kaleeswaran , S. Chithra , P. Swarnamughi , Mohammad Nikpassand , Jayavelu Udaya Prakash","doi":"10.1016/j.jics.2025.101657","DOIUrl":"10.1016/j.jics.2025.101657","url":null,"abstract":"<div><div>The study's main objectives were to develop and synthesize hybrid pyrazole derivatives from 1,3-diphenyl-1H-pyrazole-4-carbaldehyde and assess their anticancer potential using molecular docking and DFT simulations. The DFT/B3LYP functional and 6-311+G (d, p) basis set were used to computationally describe the title chemical utilizing quantum mechanics method. Theoretical and experimental FT-IR studies were presented, and vibrational wavenumbers scaled. The research included a number of investigations, such as the examination of Frontier Molecular Orbital (FMO), the computation of the HOMO-LUMO energy gap, the Modeling of UV spectra using Time-Dependent Density Functional Theory (TD-DFT), and the assessment of Light Harvesting Efficiency (LHE). The properties of Natural Bond Orbital and Non-Linear Optical (NLO) were calculated. The title molecule's reactive sites were found using a multi-technical computational approach that included LOL for orbital distribution analysis, RDG analysis for examining non-covalent interactions and possible chemical reactivity hotspots, ELF for electron pairing and localization studies, charge transfer analysis for electron density shift examination, and MEP analysis for charge distribution mapping. Bioactivity evaluation indicated that the title molecule does conform to Lipinski's rule and is also quite good in terms of drug-likeness. Additionally, molecular docking investigations showed encouraging protein-ligand binding interactions, indicating that the substance has anticancer properties.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101657"},"PeriodicalIF":3.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and synthesis of benzylidene derivatives of curcumin, and evaluation of its antioxidant and chelating activities

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-03 DOI: 10.1016/j.jics.2025.101656

Chandani G. Halpani, Satyendra Mishra

{"title":"Design and synthesis of benzylidene derivatives of curcumin, and evaluation of its antioxidant and chelating activities","authors":"Chandani G. Halpani, Satyendra Mishra","doi":"10.1016/j.jics.2025.101656","DOIUrl":"10.1016/j.jics.2025.101656","url":null,"abstract":"<div><div>A number of curcumin derivatives, including 4-arylidene curcumin derivatives (4-arylidene-1,7-bisaryl-hepta-1,6-diene-3,5-diones), have been synthesised, purified and characterized. 4-(4-Hydroxy-3-methoxybenzylidene) curcumin <strong>(3;</strong> IC<sub>50</sub>; 35 ± 2.02), 4-(4-Hydroxy-benzylidene) curcumin <strong>(9;</strong> IC<sub>50</sub>; 42 ± 0.9), and 4-(3, 4, 5-trimethoxybenzylidene) curcumin <strong>(10;</strong> IC<sub>50</sub>; 58 ± 2.0), were found to have more antioxidant property than ascorbic acid (IC<sub>50</sub>; 111 ± 1.20), in the DPPH. Additionally, it was shown that 4-(4-Hydroxy-3-methoxybenzylidene) curcumin <strong>(3;</strong> IC<sub>50</sub>; 1.42 ± 0.11), 4-(4-Hydroxy-benzylidene) curcumin <strong>(9;</strong> IC<sub>50</sub>; 1.73 ± 0.026), and 4-(3, 4, 5-trimethoxybenzylidene) curcumin <strong>(10;</strong> IC<sub>50</sub>; 2.53 ± 0.145) exhibited higher antioxidant activity in ABTS assays than ascorbic acid (IC<sub>50</sub>; 2.53 ± 0.01). However, Fe<sup>2+</sup> chelating activity of 4-(4-Hydroxy-3-methoxybenzylidene) curcumin <strong>(3;</strong> 54 ± 3.5), 4-pyridilidene curcumin <strong>(4;</strong> 42 ± 1.8), 4-(4-Hydroxy-benzylidene) curcumin <strong>(9;</strong> 56 ± 0.1<strong>)</strong> and 4-(3, 4, 5-trimethoxybenzylidene) curcumin <strong>(10;</strong> 57 ± 2.4<strong>)</strong> exhibited better chelating activity than EDTA (35 ± 2.1). The structural activity relationship (SAR) has been used in this study to investigate the free radical scavenging and Fe<sup>2+</sup> chelating activity of curcumin and its derivatives. Studies on chelating and antioxidant activity has shown that this class of 4-arylidene curcumin derivatives has much better chelating and antioxidant activity than curcumin, the parent molecule.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101656"},"PeriodicalIF":3.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ZnFe2O4-SiO2@PC-Ni nanoparticles for one-pot, solvent-free synthesis of imidazo[1,2-a]pyridines by A3 coupling reactions under ultrasound conditions

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-03-03 DOI: 10.1016/j.jics.2025.101653

Fadhil Faez Sead , Vicky Jain , Suhas Ballal , Abhayveer Singh , Sofia Gupta , Girish Chandra Sharma , Pushpa Negi Bhakuni , Mosstafa Kazemi , Ramin Javahershenas

{"title":"ZnFe2O4-SiO2@PC-Ni nanoparticles for one-pot, solvent-free synthesis of imidazo[1,2-a]pyridines by A3 coupling reactions under ultrasound conditions","authors":"Fadhil Faez Sead , Vicky Jain , Suhas Ballal , Abhayveer Singh , Sofia Gupta , Girish Chandra Sharma , Pushpa Negi Bhakuni , Mosstafa Kazemi , Ramin Javahershenas","doi":"10.1016/j.jics.2025.101653","DOIUrl":"10.1016/j.jics.2025.101653","url":null,"abstract":"<div><div>This study reports the development of ZnFe<sub>2</sub>O<sub>4</sub>–SiO<sub>2</sub>@PC-Ni magnetic nanoparticles as a novel by immobilizing phycocyanin onto magnetized silica and then immobilizing Ni (II) ions using nickel (II) chloride, the recyclable heterogeneous catalyst for the efficient one-pot synthesis of imidazo[1,2-<em>a</em>]pyridines via A3 coupling reactions under solvent-free ultrasound irradiation. Utilizing 2-aminopyridine, various aldehydes, and alkynes, the reactions were conducted solvent-free under ultrasound conditions, enhancing reaction rates and sustainability. The core-shell nanocomposite, comprising a ZnFe2O4 magnetic core, silica interlayer, and porous carbon-supported nickel shell, was characterized by XRD, TEM, BET, and VSM analyses. The synergistic effects of Ni active sites, high surface area, and magnetic retrievability enabled rapid catalytic activation of the three-component reaction between aldehydes, amines, and alkynes. Ultrasound irradiation significantly enhanced mass transfer and reaction kinetics, achieving 90–95 % yields within 10–20 min under mild conditions. The catalyst demonstrated exceptional stability, retaining >88 % activity over six cycles, and facile magnetic separation minimized metal leaching. This eco-friendly protocol eliminates toxic solvents, reduces energy consumption, and offers broad substrate scope, including aromatic, heteroaromatic, and aliphatic substrates. This work not only contributes a novel catalyst to the field of organic synthesis but also aligns with environmental directives by minimizing hazardous solvent use and employing energy-efficient reaction conditions.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101653"},"PeriodicalIF":3.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Size-tuned silver nanoparticles by a non-gassing electro-osmotic pump-driven microfluidic device

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2025-02-28 DOI: 10.1016/j.jics.2025.101641

Vidhiben Dave , Sooraj Sreenath , Gopala Ram Bhadu , Nitin G. Borle , Govind Sethia , Rajaram K. Nagarale

{"title":"Size-tuned silver nanoparticles by a non-gassing electro-osmotic pump-driven microfluidic device","authors":"Vidhiben Dave , Sooraj Sreenath , Gopala Ram Bhadu , Nitin G. Borle , Govind Sethia , Rajaram K. Nagarale","doi":"10.1016/j.jics.2025.101641","DOIUrl":"10.1016/j.jics.2025.101641","url":null,"abstract":"<div><div>Silver nanoparticles (AgNPs) are extensively used in various fields, but conventional synthesis techniques often face limitations in achieving precise control over particle size and morphology. To address this challenge, we explored the use of a microfluidic approach for synthesizing size-tuned AgNPs. Scaling down the reactor dimensions provides better control of the process of AgNPs synthesis and enables a low consumption and a high conversion of the reagents. The study aimed to utilize non-gassing electro-osmotic pumps (EOPs) connected to a three-way Y-junctioned microfluidic device for achieving controlled nanoparticle synthesis. The EOP design features a silica frit sandwiched between two flow-through electrodes composed of an Ag–Fe–O composite material. Performance evaluations revealed that the electro-osmotic flux was linearly dependent on applied voltage, with a maximum flow rate of 175.16 μL min<sup>−1</sup> cm<sup>−2</sup> achieved at 5.0 V. Optimized device parameters demonstrated effective nanoparticle synthesis, producing uniform AgNPs with sizes ranging from 10 to 15 nm at the maximum flow rate. Furthermore, particle size was found to vary directly with the voltage applied to the individual pumps. The synthesized nanoparticles were extensively characterized, and a long-term stability study confirmed their dispersion remained aggregation-free over 210 days. This research highlights the successful integration of microfluidic technology and EOPs for controlled AgNP synthesis, offering a scalable and precise platform for applications requiring consistent nanoparticle size and stability.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"102 5","pages":"Article 101641"},"PeriodicalIF":3.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0