Bio-oil from Trichosanthes cucumerina seeds: Extraction, phytochemical profiling, antimicrobial potential, and fuel properties

IF 3.4 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Journal of the Indian Chemical Society Pub Date : 2025-10-09 DOI:10.1016/j.jics.2025.102179

Govindhan Perumal , Dharmendrakumar Mahendradass

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Abstract

Lifestyle changes and environmental factors significantly contribute to the prevalence of various disorders. Medicinal plants are gaining importance in the food and pharmaceutical industries due to their role in disease prevention and treatment. This study focuses on the extraction and characterization of bio-oil from T. cucumerina seed, aiming to isolate its phytoconstituents, Antimicrobial activities, and perform elemental analysis (K, Ca, Na, Mg, Fe, Zn, Pb, Mn, Ni, and Cu). Additionally, the study assesses the physicochemical properties of the bio-oil, including yield percentage, free fatty acid content, and acidity. Parameters such as extraction temperature, duration, solvent-to-seed ratio, and seed particle size were analysed. The maximum oil yield (31.19 wt%) was obtained using n-hexane solvent, with a crushed seed size of 0.25 mm, an extraction period of 120 min, a temperature of 60 °C, and a solvent-to-seed ratio of 15:1 (ml/g). The reaction followed first-order kinetics with an activation energy of 63.604 kJ mol⁻¹. The bio-oil was characterized using FTIR, GC-MS, HPLC, and ¹H NMR. The antimicrobial activity against pathogens indicates its potential usefulness as an antiseptic. The results suggest that the bio-oil has potential applications in the medicinal, and biodiesel industries.

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瓜蒌籽生物油：提取、植物化学分析、抗菌潜力和燃料特性

生活方式的改变和环境因素显著地促进了各种疾病的流行。药用植物由于其在疾病预防和治疗中的作用，在食品和制药工业中越来越重要。本研究主要从黄瓜籽中提取生物油，并对其进行成分分离、抑菌活性分析和元素分析（K、Ca、Na、Mg、Fe、Zn、Pb、Mn、Ni、Cu）。此外，该研究还评估了生物油的理化性质，包括产率、游离脂肪酸含量和酸度。对萃取温度、萃取时间、溶剂与种子比、种子粒度等参数进行了分析。在正己烷溶剂条件下，籽粒碎度为0.25 mm，提取时间为120 min，提取温度为60℃，溶剂与籽粒比为15:1 (ml/g)，得油率最高（31.19 wt%）。反应符合一级动力学，活化能为63.604 kJ mol−1。采用FTIR、GC-MS、HPLC、1H NMR等方法对生物油进行了表征。对病原体的抗菌活性表明其作为防腐剂的潜在用途。结果表明，该生物油在医药、生物柴油等领域具有潜在的应用前景。

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来源期刊

Journal of the Indian Chemical Society 化学-化学综合

CiteScore

3.50

自引率

7.70%

发文量

492

审稿时长

3-8 weeks

期刊介绍： The Journal of the Indian Chemical Society publishes original, fundamental, theorical, experimental research work of highest quality in all areas of chemistry, biochemistry, medicinal chemistry, electrochemistry, agrochemistry, chemical engineering and technology, food chemistry, environmental chemistry, etc.