Journal of the Indian Chemical Society最新文献_第10页

Preparation, in vitro and in silico antioxidant and antibacterial studies of 4-aminoacetanilide azo derivatives 4- 氨基乙酰苯胺偶氮衍生物的制备、体外及硅学抗氧化和抗菌研究

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-09-05 DOI: 10.1016/j.jics.2024.101341

{"title":"Preparation, in vitro and in silico antioxidant and antibacterial studies of 4-aminoacetanilide azo derivatives","authors":"","doi":"10.1016/j.jics.2024.101341","DOIUrl":"10.1016/j.jics.2024.101341","url":null,"abstract":"<div>A new series of new 4-aminoacetanilide azo derivatives 1–13 were successfully synthesised via a diazo coupling reaction and gave a good to excellent yield of 73 %–93 %. The antioxidant capabilities of the series 1–13 screened through 2,2′-diphenyl-1-picrylhydrazyl (DPPH) assay and ferric reducing antioxidant power (FRAP) assay showed promising data of 12.6–199.4 ppm and 12.65–210.9 mg/ml Trolox equivalent, respectively. The findings supported by in silico docking analysis targeted Heme oxygenase-1 (HO-1) evidenced by a binding score of – 7.2 to – 8.2 kcal/mol outperforming the standard, ascorbic acid scoring only – 5.7 kcal/mol. Among all, compound 11 displayed the highest antioxidant potential with IC25 of 12.6 ppm against DPPH assay and 210.9 mg/ml Trolox for FRAP assay believed owing to the presence of methoxy group at ortho position in the phenolic compound that effectively lowered the ionisation potential and high up energy of highest occupied molecular orbital (HOMO). Nevertheless, the antibacterial potential of the series screened through the Kirby-Bauer disc diffusion method against Escherichia coli and Staphylococcus aureus showed no antibacterial activity postulated due to the presence of amide and acetyl group restricted the ability of the compound to form an interaction with the protein receptor of bacteria tested. This study provided new insight into the development of dual-functional drugs for non-communicable diseases and antimicrobial resistance.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142151594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thiosemicarbazone-based Dioxomolybdenum (VI) complexes as inorganic nucleases 作为无机核酸酶的硫代氨基羰基二氧钼 (VI) 复合物

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-09-05 DOI: 10.1016/j.jics.2024.101361

{"title":"Thiosemicarbazone-based Dioxomolybdenum (VI) complexes as inorganic nucleases","authors":"","doi":"10.1016/j.jics.2024.101361","DOIUrl":"10.1016/j.jics.2024.101361","url":null,"abstract":"<div><div>This study focuses on the design of alkyl-substituted thiosemicarbazones from 5-bromosalicylaldehyde and substituted thiosemicarbazides and the corresponding dioxomolybdenum(VI) complexes, hitherto unreported. In addition to elemental analyses, the synthesized ligands and the corresponding complexes are further analyzed by physico-chemical and spectroscopic techniques. The DNA interaction studies are based on UV absorption titration and gel electrophoretic methods. The binding constants (Kb) for the ligands (L1-L4) are found to be 1.20 ± 0.1 × 104 M−1; 1.32 ± 0.2 × 104 M−1; 1.27 ± 0.3 × 104 M−1 and 1.25 ± 0.3 × 104 M−1 respectively and that of the complexes (C1–C4) are 1.45 ± 0.2 × 104 M−1; 2.10 ± 0.4 × 104 M−1; 1.54 ± 0.2 × 104 M−1 and 2.13 ± 0.2 × 104 M−1, respectively. The complexes have shown relatively higher binding propensity as compared to that of the ligands. Further, as the outcome of gel electrophoresis studies, the ligands show a cleavage pattern of nicked circular (Form I). However, the complexes show cleavage patterns of both nicked circular and supercoiled, Forms I & II respectively. This implies that both the ligands and complexes possess varying binding efficacy with DNA and accordingly the cleavage patterns also differ.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142311636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on chemical modification of locust bean gum for enhanced functionality 关于对槐豆胶进行化学改性以增强其功能的研究

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-09-04 DOI: 10.1016/j.jics.2024.101360

{"title":"Study on chemical modification of locust bean gum for enhanced functionality","authors":"","doi":"10.1016/j.jics.2024.101360","DOIUrl":"10.1016/j.jics.2024.101360","url":null,"abstract":"<div>The present study focused on modifying Locust bean gum (LBG) to alter its physical properties, including hydration and cold-water solubility. The chemical modification process for LBG was optimized for scalability by adjusting the reaction medium and mixture of ethanol and water in a ratio of 60:40. The optimized reaction medium had a sufficient amount of water, which allowed the uncoiling of the chains and aided in the scalability of the process. The LBG was subjected to acid modification using various acids with and without the addition of sodium bicarbonate. Results revealed that LBG modified with HCl exhibited enhanced crystallinity, reduced water absorption by 2 folds, reduction in emulsion stability by 20 %, and superior hydrophobicity in comparison to control LBG majorly due to the change in mannose to galactose ratio (9.1:1). On the other hand, the sodium salt of modified LBG exhibited greater amorphousness, increased solubility by 20 %, and a remarkable ∼7-fold increase in surface area. Additionally, there was a ∼5-fold drop in the average pore diameter compared to the control LBG. These results demonstrate the potential for chemical modifications to modify the physical properties of LBG for specific applications.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142151596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile synthesis of Tl, Pb, and Bi doped CeO2 nanoparticles and the evaluation of their in-vitro cytotoxicity and photocatalytic performance 掺杂 Tl、Pb 和 Bi 的 CeO2 纳米粒子的简易合成及其体外细胞毒性和光催化性能评估

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-09-03 DOI: 10.1016/j.jics.2024.101350

{"title":"Facile synthesis of Tl, Pb, and Bi doped CeO2 nanoparticles and the evaluation of their in-vitro cytotoxicity and photocatalytic performance","authors":"","doi":"10.1016/j.jics.2024.101350","DOIUrl":"10.1016/j.jics.2024.101350","url":null,"abstract":"<div>Our work attempted a green route for provisioning of thallium, lead, and bismuth into cerium oxide nanoparticles (Tl, Pb, and Bi–CeO2 NP) via the application of Alhagi maurorum. We configured the physicochemical attributes of procured NPs via PXRD, Raman, FESEM/PSA/EDX, and UV–Vis/DRS assessments. Attendance of doped metals in structure of CeO2 was confirmed by outcomes of PXRD and EDX analyses. Next to the porous morphology, FESEM images also demonstrated the induced alterations in particle size after the doping of different metals. We also tested the photocatalytic function of synthesized NP on Methylene blue (MB) dye on UV light, which displayed the superior degradation functionality of Tl–CeO2 NP. The toxicity function of synthesized pure and Tl, Pb, and Bi–CeO2 NP on breast cancer cell (MDA-MB-231) and breast normal cell (MCF-10 A) lines was considered through the results of MTT trial. The outcomes of synthesized NPs displayed no signs of any cytotoxic effects against MCF-10 A and MDA-MB-231 cells, which signified the creation of non-toxic nanoparticles by the introduced doping process. Therefore, we suggest the applicability of our product in drug delivery systems and also industrial implementations similar to dye photodegradation and annihilation of pollution.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142164596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, spectral, DFT and anticancer studies on bis(N-(3-methoxybenzyl)-N-(pyridin-3-ylmethyl)dithiocarbamato-S,S’)M(II) (M= Pd, Pt) 双(N-(3-甲氧基苄基)-N-(吡啶-3-基甲基)二硫代氨基甲酸-S,S')M(II) (M= Pd, Pt) 的合成、光谱、DFT 和抗癌研究

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-09-03 DOI: 10.1016/j.jics.2024.101357

{"title":"Synthesis, spectral, DFT and anticancer studies on bis(N-(3-methoxybenzyl)-N-(pyridin-3-ylmethyl)dithiocarbamato-S,S’)M(II) (M= Pd, Pt)","authors":"","doi":"10.1016/j.jics.2024.101357","DOIUrl":"10.1016/j.jics.2024.101357","url":null,"abstract":"<div>We reported synthesis of bis(N-(3-methoxybenzyl)-N-(pyridin-3-ylmethyl)dithiocarbamato-S,S’)M(II) (where M(II) = palladium(II) (1), platinum(II) (2)). Both the complexes were characterized by elemental analysis, FTIR, UV–visible, 1H and 13C NMR spectroscopy. Based on FTIR spectral studies, bidentate coordination of dithiocarbamate ligand was proposed for both complexes. UV–visible spectral data confirm the formation of square planar complexes. The structure properties, frontier molecular orbital (FMO), molecular electrostatic potential (MEP), chemical reactivities and Mulliken charges were investigated using density functional theory (DFT)/B3LYP methods with 6-31+G (d, p) basis sets and LanL2DZ for light atoms and heavy atoms, respectively. FMO and Mulliken charges recognize the chemical active sites of 1 and 2 responsible for its chemical activity. In vitro anticancer activity of complexes 1 and 2 were analyzed on MCF-7 by MTT assay method. Results show that platinum complex 2 has higher activity compared to these of palladium complex 1.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142151595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient photodegradation of methylene blue dye using cerium-doped titanium dioxide (Ce@TiO2) photocatalyst under visible light irradiation 在可见光照射下使用掺铈二氧化钛（Ce@TiO2）光催化剂高效光降解亚甲基蓝染料

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-08-31 DOI: 10.1016/j.jics.2024.101356

{"title":"Efficient photodegradation of methylene blue dye using cerium-doped titanium dioxide (Ce@TiO2) photocatalyst under visible light irradiation","authors":"","doi":"10.1016/j.jics.2024.101356","DOIUrl":"10.1016/j.jics.2024.101356","url":null,"abstract":"<div>Water pollution is one of the important threats nowadays, to meet the difficulties several studies are being processed. This work aims to improve water quality by breaking dye components from the waste effluents of textile industries. Methylene blue (MB) widely used textile colorant brings several health issues to all living categories aquatic and terrestrial, including humans. All new syntheses of Cerium-doped Titanium dioxide (Ce@TiO2) nanoparticles have been achieved and proven to be a super-efficient photocatalyst for the photodegradation of MB in wastewater samples. This photocatalyst was prepared using the sol-gel technique without any hazardous chemicals in moderate conditions. The formation of Ce@TiO2 is confirmed by different characterization using XRD, FTIR, SEM-EDS, and HR-TEM analysis. The photocatalytic efficiency of Ce@TiO2 photocatalyst is carried out with varying parameters such as pH, contact time, photocatalyst dose, and MB concentration. Ce@TiO2 is an effective photocatalyst for MB degradation from wastewater at optimized conditions with 92 % removal within 90 min of reaction time. The degradation kinetics follow a pseudo-first-order model, with a rate constant (K) of 0.027min−1, while achieving a remarkable total organic carbon elimination of over 90.0 %. Furthermore, the reusability test showcased the remarkable stability of Ce@TiO2 over four cycles, with only a minor decline (<8 %) observed in MB degradation efficiency.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142151593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid removal of methyl orange from aqueous media by modified Mg–Al layered double hydroxides 利用改性镁铝双层氢氧化物快速去除水介质中的甲基橙

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-08-31 DOI: 10.1016/j.jics.2024.101355

{"title":"Rapid removal of methyl orange from aqueous media by modified Mg–Al layered double hydroxides","authors":"","doi":"10.1016/j.jics.2024.101355","DOIUrl":"10.1016/j.jics.2024.101355","url":null,"abstract":"<div>The current work deals with the synthesis of polymer modified synthetic clay, composed of Mg–Al layered double hydroxides (LDHs) and using a non-toxic organic polymer polyethylene glycol-400 (PEG400). A series of polymer-composites of Mg–Al LDH (LDHP-400) are prepared by changing concentrations of PEG-400 from 4% to 20 %, to find out the maximum adsorption efficiency for the adsorption of an industrially important anionic azo dye, MO from aqueous. The results depicted that LDH-P400, with 16 % PEG-400 shown the removal efficiency of 99.49 % for 100 ppm solution of MO (20 min). Effect of different factors such as dose of adsorbate, temperature, contact time, and pH of the solution, etc. are systematically investigated using batch experiments and thermodynamics parameters as well as kinetic studies are also carried out for the quick and instantaneous removal of MO from aqueous media. Maximum adsorption capacity of 198 mg/g has been achieved at pH4.2 and at temperature 313K for 100 ppm (mg/l) of MO in aqueous media using 0.5 g/l of adsorbent dose. Desorption studies reveal that prepared LDHP-400 can be reused and recycle up to three successive cycles with achieving 88.23 % recovery of MO, which confirmed that prepared LDHP-400 can be reused effectively for laboratory or industrial wastewater which has MO concentrations up to 100 ppm.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0019452224002358/pdfft?md5=2e5d78cf23ade361cbf781b62e9967a2&pid=1-s2.0-S0019452224002358-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymmetric pseudocapacitive electrodes for high energy density supercapacitor in aqueous electrolyte 水基电解质中用于高能量密度超级电容器的不对称伪电容电极

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-08-31 DOI: 10.1016/j.jics.2024.101354

引用次数: 0

Biosorptive removal of toxic nitrate ion from wastewater using Albizia lebbeck seed pods: Isotherm and equilibrium studies 利用Albizia lebbeck豆荚生物吸附去除废水中的有毒硝酸盐离子：等温线和平衡研究

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-08-31 DOI: 10.1016/j.jics.2024.101353

{"title":"Biosorptive removal of toxic nitrate ion from wastewater using Albizia lebbeck seed pods: Isotherm and equilibrium studies","authors":"","doi":"10.1016/j.jics.2024.101353","DOIUrl":"10.1016/j.jics.2024.101353","url":null,"abstract":"<div>A major environmental issue that contaminates drinking water and endangers human health is nitrate pollution. In this study, goethite, citric acid, tartaric acid was employed to modify Albizia lebbeck seed pod for the biosorption of nitrate ion. The developed unmodified Albizia lebbeck (UALB), citric acid modified Albizia lebbeck (CALB), tartaric acid modified Albizia lebbeck (TALB), and goethite acid modified Albizia lebbeck (GALB) were characterized using scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), and point of zero charge (pHpzc) to determine the structural morphology, functional group, and adsorbent surface charge. The adsorption nitrate ion onto the biosorbents was found to be dependent on the operating parameters. The findings revealed that the maximum percentage removal of nitrate ion was 80.8 % at pH 7 for UALB, 80.3 % at pH = 4.0 for CALB, 70.30 % at pH = 3.0 for TALB and 76 % at pH 7 for GALB. The adsorption experimental data for nitrate ion adsorption onto ULAB, CALB, TALB, and GALB were best described by the Langmuir isotherm model. The UALB exhibited the highest Langmuir monolayer adsorption capacities with a value of 344.827 mg/g. Therefore, the unmodified form of Albizia lebbeck (UALB) which is economical, and sustainable provides an efficient alternative method for nitrate removal in aqueous environment.</div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142129675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermoelectric properties of polycrystalline pristine and Pb-doped SnS materials using a conventional hydrothermal method 采用传统水热法研究原始多晶和掺杂铅的 SnS 材料的热电特性

IF 3.2 4区化学

Journal of the Indian Chemical Society Pub Date : 2024-08-30 DOI: 10.1016/j.jics.2024.101351

{"title":"Thermoelectric properties of polycrystalline pristine and Pb-doped SnS materials using a conventional hydrothermal method","authors":"","doi":"10.1016/j.jics.2024.101351","DOIUrl":"10.1016/j.jics.2024.101351","url":null,"abstract":"<div><div>Tin Sulfide (SnS) has recently garnered significant attention due to its impressive Seebeck coefficient and low thermal conductivity. However, its electrical performance is notably poor, necessitating appropriate doping for its enhancement. To address this, we employed the conventional hydrothermal method to synthesize polycrystals of pristine and lead (Pb)-doped SnS samples to observe the impact on thermoelectric parameters. Utilizing FESEM, we obtained sheet sizes on the nanometer scale and observed irregular sheet-type morphology. HRTEM analysis confirmed the polycrystalline nature of the synthesized samples. Thermal stability assessment through thermogravimetric analysis (TGA) was conducted on all samples up to a temperature of 600 °C. The hydrothermal method resulted in nanostructuring that effectively suppressed the thermal conduction of low-frequency phonons, with increased phonon scattering attributed to the small grain size of particles. For pristine SnS nanoparticles, we determined the lowest total thermal conductivity (κT) to be 0.18 W (m-K)−1, and the highest Seebeck coefficient reached 412.71 μVK−1 at 620 K. In the case of the SnS–Pb(3 wt%) doped sample, there was a slight reduction in the total thermal conductivity (κT) compared to the pristine SnS sample. The pristine SnS sample exhibited the highest electrical conductivity (σ) of 0.21 S/cm at 620 K. In contrast, the SnS–Pb(3 wt%) doped sample demonstrated a twofold increase in electrical conductivity, measuring 0.38 S/cm at 620 K. This enhancement can be attributed to the increased carrier concentration resulting from the Pb(3 wt%) doping of SnS.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142428594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0