Journal of psychoactive drugs最新文献_第4页

Interactions Between Depressive Symptoms, Childhood Trauma, and Drug Craving in Chinese Men with Methamphetamine Use Disorder: A Network Analysis. 中国男性甲基苯丙胺使用障碍患者抑郁症状、童年创伤和药物渴求之间的相互作用：一个网络分析

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-03-05 DOI: 10.1080/02791072.2025.2474747

Deyang Li, Dongmei Wang, Yang Tian, Zhaohe Chang, Jiajing Chen, Lianglun Jia, Fabing Fu, Xiaotao Wang, Xiang-Yang Zhang

{"title":"Interactions Between Depressive Symptoms, Childhood Trauma, and Drug Craving in Chinese Men with Methamphetamine Use Disorder: A Network Analysis.","authors":"Deyang Li, Dongmei Wang, Yang Tian, Zhaohe Chang, Jiajing Chen, Lianglun Jia, Fabing Fu, Xiaotao Wang, Xiang-Yang Zhang","doi":"10.1080/02791072.2025.2474747","DOIUrl":"10.1080/02791072.2025.2474747","url":null,"abstract":"Drug craving in methamphetamine use disorder (MAUD) patients is influenced by various adverse psychological problems. This study adopted network analysis to investigate the interrelationships between psychological correlates and drug craving and identify the critical pathways between them. A total of 757 men with MAUD were recruited from a drug rehabilitation center in southwest China. They completed self-report scales to measure emotion regulation, depressive symptoms, childhood trauma, and drug craving. We conducted a network analysis to assess the interaction between psychological variables and drug craving. Network structural features included network centrality, stability, and bridge strength. Results revealed positive correlations between various psychological correlates and drug craving. Limited access to emotion regulation strategies, lack of emotional awareness, and non-acceptance of emotional responses emerged as the nodes with the highest strength centrality. A bridge function analysis identified that depressive symptoms, emotional abuse, and negative reinforcement were the main bridges connecting psychological problems and drug craving. These findings support the interaction between affective factors, childhood traumatic experiences, and drug craving. Central symptoms (e.g. limited access to emotion regulation strategies) and key bridge symptoms (e.g. depressive symptoms) may serve as potential targets for intervention for MAUD patients undergoing withdrawal treatment.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"497-507"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methamphetamine Use Practices, Motivations, and Perceived Benefits and Risks: Exploring Differences Between Males and Females. 甲基苯丙胺使用实践，动机和感知的利益和风险：探索男性和女性之间的差异。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-03-14 DOI: 10.1080/02791072.2025.2478090

Madeline Hooten, Sydney Silverstein, Raminta Daniulaityte

{"title":"Methamphetamine Use Practices, Motivations, and Perceived Benefits and Risks: Exploring Differences Between Males and Females.","authors":"Madeline Hooten, Sydney Silverstein, Raminta Daniulaityte","doi":"10.1080/02791072.2025.2478090","DOIUrl":"10.1080/02791072.2025.2478090","url":null,"abstract":"Methamphetamine use has increased across the US. To develop adequate interventions, understanding differences in male and female methamphetamine use is critical. Conducted in Dayton, Ohio, this study explores sex differences in attitudes and practices of methamphetamine use. Between 12/2019 and 11/2021, the study recruited 91 participants. Bivariate analyses were used to identify sex differences. Of the 91 participants, 52.7% were female, 95.6% were non-Hispanic white, and the mean age was 42.4 (SD 10.6) years. Age of methamphetamine initiation was similar for males and females (31.7 vs. 29.3). Participants reported multiple reasons for methamphetamine use, but females were more likely to report use to quit opioids (60.4% vs. 39.5%, p = .047), lose weight (35.4% vs. 14.0%, p = .019), and self-treat ADHD symptoms (43.8% vs. 16.3%, p = .005). Females were more likely to endorse increased productivity (81.3% vs. 48.8%, p = .001) as a benefit of methamphetamine use. Females were also more likely to endorse the following perceived risks of methamphetamine: depression (91.7% vs. 74.4%, p = .027), skin problems (100.0% vs. 76.2%, p = <0.001), aggression/violence (93.8% vs. 65.1%, p = <0.001), risk of HIV/AIDS (85.4% vs. 60.5%, p = .007), teeth problems (100.0% vs. 90.7%, p = .032), exposure to fentanyl contamination (81.3% vs. 55.8%, p = .009), and increased risk of an overdose (39.6% vs. 16.3%, p = .014).","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"526-535"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12353597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Motivations, Experiences, and Consequences of Psychedelic Use in Aotearoa New Zealand. 探索在新西兰奥特罗阿使用迷幻药的动机、经验和后果。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-03-05 DOI: 10.1080/02791072.2025.2474236

Ethan Mills, Jai Whelan, Sarah McGruddy, Ryan D Ward

{"title":"Exploring Motivations, Experiences, and Consequences of Psychedelic Use in Aotearoa New Zealand.","authors":"Ethan Mills, Jai Whelan, Sarah McGruddy, Ryan D Ward","doi":"10.1080/02791072.2025.2474236","DOIUrl":"10.1080/02791072.2025.2474236","url":null,"abstract":"While interest in psychedelic research has recently increased globally, little is known about use in Aotearoa New Zealand. Therefore, we sought to explore motivations, features of subjective experience, and impact of use. We also aimed to explore and compare positive, typical, and worst experiences. An online survey was completed by 997 individuals who had used at least one classical psychedelic in Aotearoa New Zealand. Worst, best, and typical experiences were compared, and logistic regression analysis was used to explore predictors of positive psychological health impact. Worst experiences differed substantially from best experiences across emotional, cognitive, and relational domains, while typical experiences more closely resembled best experiences. Motivations for use changed after initial experience, and motivations associated with different experience types varied. A higher number of psychedelic use occasions, as well as therapeutic and growth-oriented motivations, were significant predictors of positive psychological health impact. Consequences of psychedelic use were mostly positive, with best psychedelic experiences resulting in the most benefit. The findings highlight the potential of psychedelic experiences for personal growth and wellbeing and emphasize the need for an open-minded approach to drug education and policy development for the minimization of harm and maximization of benefit regarding psychedelics.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"452-463"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meaningful Psychedelic Experiences Predict Increased Moral Expansiveness. 有意义的迷幻体验预示着道德的扩张。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-03-12 DOI: 10.1080/02791072.2025.2478095

Will Olteanu, Sam G Moreton

引用次数: 0

Prevalence and Patterns of Cannabis Product Adulteration: An Analysis of WEDINOS Data. 大麻产品掺假的流行和模式：对WEDINOS数据的分析。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-03-19 DOI: 10.1080/02791072.2025.2478087

Simon Erridge, Martin Hall, Mikael H Sodergren

引用次数: 0

Prevalence and Correlates of Lifetime Ecstasy/MDMA Use Among Asian American and Pacific Islander Adult Populations in the United States, 2015-2020. 2015-2020年美国亚裔和太平洋岛民成年人群终身摇头丸/MDMA使用的患病率及其相关因素

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-03-03 DOI: 10.1080/02791072.2025.2474243

Wayne Kepner, Kevin H Yang, Patricia Dionicio, Katie Bailey, Nora Satybaldiyeva, Alison Moore, Benjamin H Han, Joseph J Palamar

{"title":"Prevalence and Correlates of Lifetime Ecstasy/MDMA Use Among Asian American and Pacific Islander Adult Populations in the United States, 2015-2020.","authors":"Wayne Kepner, Kevin H Yang, Patricia Dionicio, Katie Bailey, Nora Satybaldiyeva, Alison Moore, Benjamin H Han, Joseph J Palamar","doi":"10.1080/02791072.2025.2474243","DOIUrl":"10.1080/02791072.2025.2474243","url":null,"abstract":"Little is known about ecstasy/MDMA use among Asian American and Pacific Islander populations. Research is important because AAPIs face unique cultural factors that may influence use. We estimated the prevalence and correlates of lifetime ecstasy/MDMA use based on a representative sample of US AAPI adults aged ≥18 from the 2015-2020 National Survey on Drug Use and Health. An estimated 5.1% of AAPI adults used ecstasy in their lifetime. Compared to males, females had higher odds of use (aOR = 1.45, 95% CI: 1.08-1.98). Compared to those aged 18-25, those aged 26-34 were at increased odds for use (aOR = 1.99, 95% CI: 1.30-3.06), while those aged ≥50 were at lower odds for use. Lifetime use of other substances including cannabis (aOR = 28.4, 95% CI: 17.1-47.2), ketamine (aOR = 10.9, 95% CI: 1.63-73.4), LSD (aOR = 3.82, 95% CI: 1.98-7.37), cocaine (aOR = 3.77, 95% CI: 2.54-5.59), psilocybin (aOR = 3.29, 95% CI: 1.75-6.16), prescription opioids (aOR = 2.43, 95% CI: 1.44-4.09), and prescription stimulants (aOR = 1.96, 95% CI: 1.29-2.99) were associated with increased odds of ecstasy/MDMA use. We estimated that over 1 in 20 AAPI adults have ever used ecstasy/MDMA. Variations by age, sex, family income, substance type, and mental health service utilization emphasize the need for targeted public health strategies.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"470-478"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12353433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Setting the Stage for the Inner Journey: Unraveling the Interplay of Contextual Factors and the Intensity of Psychedelic-Induced Ego Dissolution. 为内心之旅设置舞台：揭示背景因素的相互作用和迷幻药诱导的自我溶解的强度。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-09-01 Epub Date: 2025-02-13 DOI: 10.1080/02791072.2025.2464797

Stanisław Adamczyk, Małgorzata Paczyńska, Anastasia Ruban, Jan Szczypiński, Michał Bola, Paweł Orłowski

{"title":"Setting the Stage for the Inner Journey: Unraveling the Interplay of Contextual Factors and the Intensity of Psychedelic-Induced Ego Dissolution.","authors":"Stanisław Adamczyk, Małgorzata Paczyńska, Anastasia Ruban, Jan Szczypiński, Michał Bola, Paweł Orłowski","doi":"10.1080/02791072.2025.2464797","DOIUrl":"10.1080/02791072.2025.2464797","url":null,"abstract":"Psychedelics have the potential to induce profound alterations in cognition, emotionality, and sensory perception. The quality and intensity of these subjective effects exhibit high intra- and inter-individual variability, which can potentially be accounted for by the variability in contexts in which psychedelics are used. Therefore, the aim of the present cross-sectional study was to investigate how internal and external contextual factors are related to the subjective intensity of psychedelic-induced ego dissolution experiences. Participants completed an online survey in which they reported their motivations for past use of psychedelic substances, and the frequency of use in different environments and social contexts. Additionally, participants completed the Ego Dissolution Inventory to evaluate the intensity of past ego dissolution experiences. Robust linear regression analysis was performed on data from 862 psychedelics users (701 had used LSD and 553 had used psilocybin mushrooms); this revealed that participants consuming psychedelics for spiritual or self-healing purposes reported more intense, while those motivated by curiosity reported less intense ego dissolution experiences. However, the social context and physical environment did not exhibit robust associations with the reported ego dissolution. Therefore, our study enhances understanding of how set and setting factors relate to psychedelic-induced ego dissolution experiences in naturalistic contexts.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"377-388"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving Psychedelic Harm Reduction and Therapy: Community Perspectives from Individuals Who Use Recreationally and for Mental Health Purposes. 改善致幻剂的危害减少和治疗：社区观点从个人谁使用娱乐和精神健康的目的。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-08-12 DOI: 10.1080/02791072.2026.2710054

Jennifer S Jewell, Caleb James, Joshua C Black

{"title":"Improving Psychedelic Harm Reduction and Therapy: Community Perspectives from Individuals Who Use Recreationally and for Mental Health Purposes.","authors":"Jennifer S Jewell, Caleb James, Joshua C Black","doi":"10.1080/02791072.2026.2710054","DOIUrl":"https://doi.org/10.1080/02791072.2026.2710054","url":null,"abstract":"There is still inconsistency in psychedelic research across the United States. There are gaps in our understanding of the psychedelic community's perception of topics including reasons for use and set/setting. The goal is to utilize these findings to produce better quantitative research, to ask the right questions of the right communities. This qualitative study organized focus groups from people who use psychedelics for: 1) recreational/spiritual and 2) mental health reasons. We conducted 10 focus groups with 29 people. The data were analyzed using Grounded Theory. A primary coder (JJ) inductively coded the transcribed audio recordings, and a secondary coder (CJ) deductively coded the data using JJ's codebook. Four themes emerged. We learned that people who use for recreational reasons often still use with purposive intent. Secondly, there is evidence of preparation and integration with their use. In those that use for mental health reasons, it was not uncommon to have a history of prior psychedelic use, and those individuals also had concerns about access to psychedelics for others who needed mental health treatment. These themes provide useful information for researchers to develop data collection tools for harm reduction and therapy techniques that are grounded in community perspectives and supportive literature.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-8"},"PeriodicalIF":2.4,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148712676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychedelic Use Covaries with Psychological Flexibility Through Mystical Experiences: Results of a Retrospective Web Survey. 迷幻药使用伴随神秘体验的心理弹性：一项回顾性网络调查结果。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-08-10 DOI: 10.1080/02791072.2026.2710057

Angelica Spata, James W Sturges, Mitch Earleywine

{"title":"Psychedelic Use Covaries with Psychological Flexibility Through Mystical Experiences: Results of a Retrospective Web Survey.","authors":"Angelica Spata, James W Sturges, Mitch Earleywine","doi":"10.1080/02791072.2026.2710057","DOIUrl":"https://doi.org/10.1080/02791072.2026.2710057","url":null,"abstract":"The therapeutic effects of psychedelic-assisted treatments covary with acute mystical experiences as well as enhancements in psychological flexibility. Psychological flexibility, a key construct in acceptance and commitment therapy (ACT), has broad benefits for adaptive functioning and well-being, making it a vital focus of psychedelic-assisted therapy. More than 200 participants (54.9% female, 70% Caucasian, 72% with a college degree) completed the Mystical Experiences Questionnaire (MEQ-30) addressing their most profound mystical experience as well as the Multidimensional Psychological Flexibility Index (MPFI) and their psychedelic use. Analyses revealed that psychedelic use had an indirect effect on psychological flexibility through mystical experiences, underscoring the potential role of mystical experiences in fostering psychological growth. Participants who had used a psychedelic reported significantly higher scores on the MEQ-30 and MPFI compared to those with only non-drug mystical experiences. The flipped model did not achieve statistical significance. These findings suggest that mystical experiences might act as a catalyst for increases in psychological flexibility, and they underscore the need for further research on the mechanisms linking mystical experiences and psychological flexibility, particularly in clinical contexts. Psychedelic-assisted therapy, informed by frameworks like ACT, shows promise for enhancing psychological flexibility and fostering long-term mental health improvements. Preparatory and integration sessions that emphasize flexibility may improve treatment outcomes.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-9"},"PeriodicalIF":2.4,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Empathy and Love as Protective Factors in Opioid Use Disorder Recovery. 共情和爱作为阿片类药物使用障碍康复的保护因素。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-08-07 DOI: 10.1080/02791072.2026.2710067

Kobe R Hanson, Nina A Cooperman, Eric L Garland

{"title":"Empathy and Love as Protective Factors in Opioid Use Disorder Recovery.","authors":"Kobe R Hanson, Nina A Cooperman, Eric L Garland","doi":"10.1080/02791072.2026.2710067","DOIUrl":"10.1080/02791072.2026.2710067","url":null,"abstract":"Opioid use disorder (OUD) is a debilitating condition that impacts multiple domains of life, including social attachment systems, which makes recovery and relapse prevention challenging. The Brain Opioid Theory of Social Attachment suggests opioids hijack mechanisms involved in love and bonding. Previous studies show that social interaction can help reduce opioid use in both animals and humans, but little is known about whether prosocial emotions like love and empathy can protect against opioid use among people treated with medications for OUD. In this cross-sectional study, data were analyzed from 189 adults receiving methadone treatment for OUD at community-based programs in New Jersey and Utah. Surveys measured opioid use, empathy, love, along with covariates including pain, anxiety, depression, social support, and stigma. Participants reported lower levels of love and empathy compared to normative samples. In zero-inflated Poisson, higher love and empathy scores were significantly associated with fewer episodes of opioid use, even after adjusting for covariates. Anxiety, pain, and social support were significant predictors, with social support unexpectedly linked to greater opioid use. Findings suggest that love and empathy can buffer against opioid use, consistent with theories that support the use of prosocial emotions that target the same pathways as opioids.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0