Journal of psychoactive drugs最新文献_第5页

Death Anxiety Among Users and Non-Users of Psychedelics. 致幻剂使用者和非使用者的死亡焦虑。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-10 DOI: 10.1080/02791072.2025.2451035

Ana Cláudia Mesquita Garcia, Lucas Oliveira Maia, Everson Meireles, Denismar Alves Nogueira, Luís Fernando Tófoli

{"title":"Death Anxiety Among Users and Non-Users of Psychedelics.","authors":"Ana Cláudia Mesquita Garcia, Lucas Oliveira Maia, Everson Meireles, Denismar Alves Nogueira, Luís Fernando Tófoli","doi":"10.1080/02791072.2025.2451035","DOIUrl":"https://doi.org/10.1080/02791072.2025.2451035","url":null,"abstract":"This study is a survey-type, cross-sectional study conducted in Brazil (n = 517), with online data collection taking place from April to June 2022. The main objective of this study was to evaluate the death anxiety in users and non-users of psychedelics. To this end, we also assessed the validity and reliability of the Death Anxiety Scale in Brazil. The following instruments were used for data collection: a questionnaire for sociodemographic characterization, Death Anxiety Scale, Death Transcendence Scale, and Spiritual Well-Being Scale. Our main results indicated the following: 1) increased death anxiety is associated with never or almost never having used psychedelics; 2) death transcendence, especially creative and religious factors, was the only constant variable in all the explanatory models of the variation in death anxiety; 3) there is a negative relationship between death anxiety and mystical and religious factors of death transcendence. We interpret these results as follows: it's not psychedelics that reduce death anxiety - psychedelics can favor the experience of transcending death. And it's the possibility of transcending death, (idea of continuity beyond physical death, taking both spiritual and symbolic forms) that helps reduce death anxiety. These findings offer valuable insights into the role of psychedelics in human mortality perception.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Index of Cannabis Equivalence (ICE): A User-Centered Approach to Standardization of Cannabis Dose-Response. 大麻等效指数（ICE）：以用户为中心的大麻剂量反应标准化方法。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-09 DOI: 10.1080/02791072.2025.2449932

Michelle St Pierre, Stacey Squires, Sarah Daniels, Tatiana Sanchez, Zach Walsh

{"title":"The Index of Cannabis Equivalence (ICE): A User-Centered Approach to Standardization of Cannabis Dose-Response.","authors":"Michelle St Pierre, Stacey Squires, Sarah Daniels, Tatiana Sanchez, Zach Walsh","doi":"10.1080/02791072.2025.2449932","DOIUrl":"10.1080/02791072.2025.2449932","url":null,"abstract":"The increasing acceptance of cannabis use, and policy changes in several jurisdictions has led researchers and public health experts to call for a standard cannabis dose. Standard dosing units are useful tools for regulation, substance use guidelines, data collection, consistency of research, as a means of communicating low-risk recommendations and dose-related effects, and for self-monitoring. Efforts to standardize cannabis dose have focused on cannabinoid content without considering tolerance or mode. Cannabis users with diverse motivations for use and varying experience rated low, medium, and high doses across seven modes of use. The participants (N = 1368; 42% female) were 18-93 years of age (M = 31.64, SD = 14.70) who had a cannabis use history. The Index of Cannabis Equivalence (ICE) identified the following low-dose cannabis equivalencies: two puffs on a joint, pipe, herbal or concentrate vaporizer is equivalent to one hit on a bong, a 5 mg/THC edible, and ¼ dab of a concentrate. These findings are based on responses from users with lower tolerance, which may limit generalizability to those with higher tolerance. The ICE proposes standardized cannabis doses through user-derived ratings across different administration routes. The meaningful standardization of units of cannabis products in a manner similar to what has been achieved for alcohol represents a valuable step in establishing standard doses across different modes of cannabis administration.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-6"},"PeriodicalIF":2.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychotic-Like Experiences in Young Recreational Users of Ketamine: A Case Study. 青少年娱乐性氯胺酮使用者的精神病样经验：个案研究。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-08 DOI: 10.1080/02791072.2025.2449909

Valerio Ricci, Domenico De Berardis, Sheikh Shoib, Giovanni Martinotti, Giuseppe Maina

{"title":"Psychotic-Like Experiences in Young Recreational Users of Ketamine: A Case Study.","authors":"Valerio Ricci, Domenico De Berardis, Sheikh Shoib, Giovanni Martinotti, Giuseppe Maina","doi":"10.1080/02791072.2025.2449909","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449909","url":null,"abstract":"This study explores the psychotic-like experiences (PLEs) associated with recreational ketamine use among young adults. Ketamine, initially introduced as an anesthetic, is now widely used recreationally for its dissociative effects, raising concerns about its impact on mental health. Ten participants aged 18-24, who used ketamine recreationally multiple times a week, were assessed using the Community Assessment of Psychic Experiences (CAPE-42). Results showed a significant positive correlation between the frequency of ketamine use and PLEs, with no significant impact from other substances like THC, MDMA, and alcohol. These findings confirm ketamine's potential to induce psychotic-like symptoms by antagonizing NMDA receptors, similar to schizophrenia. The study underscores the need for preventive measures and targeted interventions to address the mental health risks of frequent ketamine use, particularly among young adults. However, limitations such as the small sample size and reliance on self-reported data suggest that further research is needed to establish causality and examine long-term effects. Overall, this study highlights the significant association between recreational ketamine use and increased PLEs, emphasizing the importance of early detection and intervention strategies.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Psilocybin Experience Gone Wrong: The Importance of Psychedelic Assisted Psychotherapy. 裸盖菇素的错误体验：迷幻辅助心理治疗的重要性。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-07 DOI: 10.1080/02791072.2025.2449918

Fernando Espi Forcen

引用次数: 0

Ketamine-Assisted Psychotherapy for Antisocial Personality Disorder: A Case Report. 氯胺酮辅助治疗反社会型人格障碍1例报告。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-07 DOI: 10.1080/02791072.2025.2449911

Matthew R Hicks, Heather Zwickey, Ryan Bradley

引用次数: 0

Cumulative Social Disadvantage and Medicinal Cannabis Use Among Younger Adults in Rural Communities: A Mixed Methods Approach.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-07 DOI: 10.1080/02791072.2025.2449919

Sharon Lipperman-Kreda, Emile Sanders, Julie Peach, Shelly Brantley, Geoffrey Hunt, Tamar M J Antin

{"title":"Cumulative Social Disadvantage and Medicinal Cannabis Use Among Younger Adults in Rural Communities: A Mixed Methods Approach.","authors":"Sharon Lipperman-Kreda, Emile Sanders, Julie Peach, Shelly Brantley, Geoffrey Hunt, Tamar M J Antin","doi":"10.1080/02791072.2025.2449919","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449919","url":null,"abstract":"This mixed-methods study investigated the role of medicinal cannabis use among younger adults who live in rural communities and experience high levels of cumulative social disadvantage (CSD). Results are based on cross-sectional surveys and online interviews with 153 younger adults (18-35-years old) in rural California. We assessed participants' levels of CSD (high, medium, and low) and examined associations with perceived general physical and mental health and with medicinal use of cannabis (MUC). Qualitative analyses were then conducted to better understand the roles of cannabis use in the lives of study participants with high versus low CSD. High CSD was associated with perceived poorer physical and mental health and with MUC, but not past month general cannabis use. Qualitative findings emphasized the significant role of MUC for rural young people with high CSD to reduce stress and manage physical and mental health. Findings suggest the need to address CSD inequities in rural communities, such as increasing access to health care, to reduce health inequities and the reliance on cannabis use for managing mental and physical health.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patterns of Opioid and NSAID Use in Saudi Arabia from 2010 to 2020. 2010年至2020年沙特阿拉伯阿片类药物和非甾体抗炎药使用模式

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-06 DOI: 10.1080/02791072.2025.2449912

Abdullah U Althemery, Mohammed Alsubaie, Hamoud Alharbi, Ammar Alqahtani, Ghazi Alsubaie, Abdulrahman Alotaibi

{"title":"Patterns of Opioid and NSAID Use in Saudi Arabia from 2010 to 2020.","authors":"Abdullah U Althemery, Mohammed Alsubaie, Hamoud Alharbi, Ammar Alqahtani, Ghazi Alsubaie, Abdulrahman Alotaibi","doi":"10.1080/02791072.2025.2449912","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449912","url":null,"abstract":"The use of analgesics has increased globally over the last three decades. Prescription drug abuse has increased significantly, and opioids have been identified as causing further harm to the world. This study explored the utilization and expenditure associated with opioids and non-steroidal anti-inflammatory drugs (NSAIDs) from 2010 to 2020 in Saudi Arabia. This descriptive time-series analysis was conducted in two major hospitals in Riyadh, Saudi Arabia, between 2010 and 2020. Data were collected from the inpatients, outpatients, and emergency departments of the Security Force Hospital and King Fahad Medical City in Riyadh. The analgesics examined included celecoxib, diclofenac sodium, ibuprofen, lornoxicam, mefenamic acid, paracetamol, and tramadol. A total of 48,106 analgesics were prescribed during this period. Peak utilization of all opioid and NSAID products occurred in 2019. Paracetamol accounted for 29.33% of all prescriptions. However, in 2020, tramadol prescriptions were the highest, accounting for 2,798 prescriptions. The average price per prescription unit decreased between 2012 and 2019 and increased in 2020 from SAR 0.87 to SAR 4.50 per unit. This study's findings can guide healthcare policy and practices and enhance the quality of treatment for patients who require analgesic treatment.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-6"},"PeriodicalIF":2.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Cannabis Product Characteristics and Pricing on Dark Web Markets. 大麻产品特性识别及暗网市场定价。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-04 DOI: 10.1080/02791072.2024.2446446

Matthew C Nali, Zhuoran Li, Vidya Purushothaman, Meng Zhen Larsen, Raphael E Cuomo, Joshua S Yang, Tim K Mackey

{"title":"Identification of Cannabis Product Characteristics and Pricing on Dark Web Markets.","authors":"Matthew C Nali, Zhuoran Li, Vidya Purushothaman, Meng Zhen Larsen, Raphael E Cuomo, Joshua S Yang, Tim K Mackey","doi":"10.1080/02791072.2024.2446446","DOIUrl":"https://doi.org/10.1080/02791072.2024.2446446","url":null,"abstract":"Growing cannabis use has made it the most widely cultivated and trafficked illicit drug globally according to the World Health Organization, with 147 million people consuming cannabis-derived products (CDPs) in various product forms and constituency. Despite restrictions in certain countries, unregulated access can still be found on the dark web which specializes in trafficking of illicit goods. The objective was to systematically collect data from multiple marketplaces to identify types of cannabis products offered for sale. The study was conducted in three phases: (1) data mining transactions on dark web markets using cannabis and tobacco keywords; (2) inductive coding of selling-related characteristics; and (3) pricing analysis of one marketplace based on product type, shipping, and cannabis policy status. Four dark web markets (Archetyp, Incognito, Royal, and Wethenorth) yielded 2,954 selling posts. The top 3 products based on keyword searches included CDPs (n = 2629, 89%), illicit and prescription drugs (n = 223, 7.55%), and psychedelics (n = 102, 3.45%). For Archetyp listings, cannabis concentrates pricing had a statistically significant difference in average price p/mg when shipped from a country with a complete prohibition. The dark web represents an unregulated digital space where numerous CDPs are sold and shipped to various countries at different prices.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling Psychedelics: One of the Most Meaningful Events in Life Associated with Improved Well-Being in Swedish Users. 揭秘迷幻药：生活中最有意义的事件之一，与改善瑞典用户的幸福感有关。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-02 DOI: 10.1080/02791072.2024.2444892

Petri J Kajonius, David Sjöström, Emma Claesdotter-Knutsson

{"title":"Unveiling Psychedelics: One of the Most Meaningful Events in Life Associated with Improved Well-Being in Swedish Users.","authors":"Petri J Kajonius, David Sjöström, Emma Claesdotter-Knutsson","doi":"10.1080/02791072.2024.2444892","DOIUrl":"https://doi.org/10.1080/02791072.2024.2444892","url":null,"abstract":"In the midst of growing research and societal discourse on psychedelic substances, a consistent finding is reported: A majority of users report profound personal meaning from their experiences. This pioneering study in Sweden, a nation renowned for its strict drug policies, sought to quantify the extent of reported meaningfulness among Swedish psychedelic users. Results revealed that a majority of the sample, 58%, ranked their psychedelic experience among the top 5 most meaningful events in their lives, while 85% among the top 10. These findings align well with previous research from other types of studies and other countries. Participants acknowledged challenging and mystical aspects as part of their psychedelic experiences, and a large majority, 94%, reported positive life improvements. Factors such as a personal growth motive and supportive social networks were associated with improved well-being. Despite many study limitations, including the self-selected sample, self-reported measures, and cross-sectional design, the findings underscore the impact psychedelic experiences potentially can have on individuals' lives.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parenting, Peers, and Alcohol Use Initiation Among Black, White, and Black-White Adolescents: Evidence Using Discrete-Time Survival Analysis. 父母、同伴与黑人、白人和黑人-白人青少年开始饮酒：使用离散时间生存分析的证据。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-01 Epub Date: 2023-12-24 DOI: 10.1080/02791072.2023.2297193

Trenette Clark Goings, Alejandro Martinez, Patrece L Joseph, Rachel Goode, Daniel Bauer

{"title":"Parenting, Peers, and Alcohol Use Initiation Among Black, White, and Black-White Adolescents: Evidence Using Discrete-Time Survival Analysis.","authors":"Trenette Clark Goings, Alejandro Martinez, Patrece L Joseph, Rachel Goode, Daniel Bauer","doi":"10.1080/02791072.2023.2297193","DOIUrl":"10.1080/02791072.2023.2297193","url":null,"abstract":"Alcohol use among Biracial adolescents remains understudied. This study examined how parenting and peer factors relate to age of alcohol use onset among Black, White, and Biracial Black-White adolescents and emerging adults. We used Add Health data to produce a final analytic sample of 13,528 adolescents who self-identified as White, Black, or Biracial Black-White. Discrete-time survival analysis implemented within logistic regression indicated Black adolescents showed the lowest probability of alcohol use onset by age 18, followed by Biracial adolescents, and White adolescents. The probability of alcohol use onset increased for Monoracial Black and White adolescents at ages 16, 18, and 21. Descriptively our model suggest that Biracial adolescents exhibit a sharp decline in their probability of alcohol use onset at age 16 and a sharp increase at age 21. However, this trend did not differ significantly from the other racial groups. Consistent with social control and learning theories, low parental acceptance, high parental control, and peer substance use were associated with alcohol use onset. Alcohol use onset trajectories differed for Monoracial and Biracial adolescents with Biracial individuals reporting greater alcohol onset in adulthood. Prevention efforts should continue to target parental acceptance, parental control, and peer substance use.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"54-61"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11194302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0