Journal of psychoactive drugs最新文献_第6页

Therapeutic Protocols Using Ketamine and Esketamine for Depressive Disorders: A Systematic Review. 使用氯胺酮和 Esketamine 治疗抑郁症的方案：系统性综述。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-08-28 DOI: 10.1080/02791072.2023.2248989

Julia M K Freind, Fernando R Beserra, Bruno S Menezes, Daniel C Mograbi

{"title":"Therapeutic Protocols Using Ketamine and Esketamine for Depressive Disorders: A Systematic Review.","authors":"Julia M K Freind, Fernando R Beserra, Bruno S Menezes, Daniel C Mograbi","doi":"10.1080/02791072.2023.2248989","DOIUrl":"10.1080/02791072.2023.2248989","url":null,"abstract":"Depression is one of the most prevalent mental health disorders globally, causing severe emotional suffering, reducing life expectancy and increasing the risk of suicide. Recently, the use of dissociative psychedelic substances such as ketamine and esketamine for depressive disorders has expanded treatment options. We sought to analyze, through a systematic review, the existing protocols for the treatment of depression with ketamine and esketamine. The search adopted PRISMA criteria and was performed using PubMed and Web of Science databases. Procedures in each study were compared, focusing on the sample recruited, therapeutic approaches, including the clinical team and professionals engaged in treatment, medical procedures, description of the setting (including music) and factors such as specific medication (ketamine or esketamine), route of administration and dosage employed. Results indicated the predominance of a medical approach, with a limited number of studies on ketamine assisted psychotherapy (KAP) and other modalities of psychedelic assisted therapy. Additionally, there is limited information on psychosocial elements such as preparation, psychological support during session and integration of experience. Altogether these findings suggest that treatment of depression with ketamine or esketamine diverges in relation to the practices employed with psychedelic substances. This is discussed considering future research directions in the field.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"496-512"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10075506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seasonal Variation of Use of Common Psychedelics and Party Drugs Among Nightclub/Festival Attendees in New York City. 纽约市夜总会/节日参与者使用常见迷幻药和派对药物的季节性变化。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-08-21 DOI: 10.1080/02791072.2023.2240322

Joseph J Palamar, Caroline Rutherford, Austin Le, Katherine M Keyes

{"title":"Seasonal Variation of Use of Common Psychedelics and Party Drugs Among Nightclub/Festival Attendees in New York City.","authors":"Joseph J Palamar, Caroline Rutherford, Austin Le, Katherine M Keyes","doi":"10.1080/02791072.2023.2240322","DOIUrl":"10.1080/02791072.2023.2240322","url":null,"abstract":"Few epidemiological studies have focused on seasonal variation in the use of common psychedelics and party drugs among nightclub and festival attendees, typically those who attend electronic dance music (EDM) events. We sought to determine whether the use of different drug types varies seasonally within this population. Across 15 seasons from summer 2017 through fall 2022, we surveyed 3,935 adults entering randomly selected nightclubs and festivals in New York City regarding their past-month use of cocaine, MDMA (3,4-methylenedioxymethamphetamine, commonly known as ecstasy), lysergic acid diethylamide (LSD), psilocybin (shrooms), and ketamine. Multivariable models were used to compare adjusted odds ratios for drug use within each season with the grand mean of combined seasons. Summer was associated with higher odds for use of LSD (aOR 2.72; 95% CI, 1.88-3.93) and psilocybin (aOR 1.65; CI, 1.12-2.43), independent of increases in psilocybin use over time (p < .001). A significant increase in use of ketamine (p = .014) and significant decreases in use of cocaine (p = .002) and ecstasy (p = .002) were found across time, but multivariable models did not detect seasonal variations. Summer is a risk factor for use of common psychedelics among people who attend EDM events. Therefore, the summer months may be the best time to disseminate information about harm reduction for psychedelic drug users.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"467-474"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10879452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10100866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploratory Growth Mixture Modeling of Cannabis-Withdrawal Syndrome Trajectories of Adult Pure Cannabis Dependents During Detoxification: Two Subtypes? 成年纯大麻依赖者戒毒期间大麻-戒断综合征轨迹的探索性增长混合模型：两种亚型？

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-07-18 DOI: 10.1080/02791072.2023.2229830

Benedikt Bernd Claus, Norbert Scherbaum, Michael Specka, Patrik Roser, Udo Bonnet

{"title":"Exploratory Growth Mixture Modeling of Cannabis-Withdrawal Syndrome Trajectories of Adult Pure Cannabis Dependents During Detoxification: Two Subtypes?","authors":"Benedikt Bernd Claus, Norbert Scherbaum, Michael Specka, Patrik Roser, Udo Bonnet","doi":"10.1080/02791072.2023.2229830","DOIUrl":"10.1080/02791072.2023.2229830","url":null,"abstract":"As clinical studies about subtypes of the cannabis withdrawal syndrome (CWS) are scant, we performed a re-analysis of longitudinal data with German adult cannabis-users seeking inpatient cannabis detoxification-treatment. Sixty-seven cannabis-dependents without active comorbidity were included for growth-mixture-analysis (GMM) of their CWS-severity-trajectories during a scheduled 24-day detox-treatment. As of treatment-day 12, thirty-six (53.7%) of 67 patients were discharged after successful detoxification. This led to artificial imputations for I-GMM. Therefore, we preferred the results of the GMM including raw data-only (R-GMM). By both, I-GMM and R-GMM, we found two classes of CWS severity time-courses. Class one (n = 44, R-GMM) showed a continuously decreasing CWS-severity; class two (n = 23, R-GMM) exhibited a sharp peak (generally between days 2-6 post-cessation). A short inpatient treatment-period and low urinary 11-nor-9-carboxy-Δ9 -tetrahydrocannabinol-level upon admission predicted the peaking trajectory of R-GMM-class-two-CWS. Withdrawal syndrome medication (PRN), comorbidity, cannabis-history data and gender balance were not significantly different between the CWS-classes. Although possibly confounded by PRN-medication, this exploratory study supports the presence of two CWS-variants in adult cannabis-dependents, characterized by a slowly decreasing (\"protracted\") slope (class one) or a clear crescendo-decrescendo trajectory (class two). The latter was associated with a significantly shorter inpatient detoxification period and lower urinary THC-COOH-levels at admission.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"551-562"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9827649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid. 乙酸 THC-O：迷幻大麻素的稀缺证据。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-06-29 DOI: 10.1080/02791072.2023.2230573

Daniel J Kruger, Carlton Cb Bone, Meredith C Meacham, Charles Klein, Jessica S Kruger

{"title":"THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid.","authors":"Daniel J Kruger, Carlton Cb Bone, Meredith C Meacham, Charles Klein, Jessica S Kruger","doi":"10.1080/02791072.2023.2230573","DOIUrl":"10.1080/02791072.2023.2230573","url":null,"abstract":"There is a growing interest in semi-synthetic cannabinoids, including THC-O-acetate (THC-Oac). Some cannabis marketers and users have claimed that THC-Oac produces psychedelic effects; the current study is the first to examine this claim. Researchers developed an online survey for THC-Oac consumers based on previous cannabis and psychedelic use surveys and in consultation with the moderator of an online forum. The survey assessed the experiential profile of THC-Oac and included items from the Mystical Experience Questionnaire (MEQ), an instrument for assessing psychedelic experiences. Participants reported a low to moderate level of cognitive distortions (altered sense of time, difficulties concentrating, difficulties with short-term memory) and few visuals or hallucinations. Participants' responses were significantly below the threshold for a complete mystical experience on all four MEQ dimensions. Participants who had used classic (5-HT2A agonist) psychedelics had lower scores on all MEQ dimensions. When asked directly, 79% responded that using THC-Oac is \"not at all\" or \"a little\" of a psychedelic experience. Some reports of psychedelic experiences may be due to expectations or contaminants. Those having prior experience with classic psychedelics had lower ratings of mystical experiences.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"563-567"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9699062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methamphetamine-Induced Wakefulness and Sleep Management: A Qualitative Analysis of Online Narratives. 甲基苯丙胺诱发的清醒和睡眠管理：对在线叙述的定性分析。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-08-20 DOI: 10.1080/02791072.2023.2246458

Sanjaya Regmi, Satish K Kedia, Michael Schmidt, Asos Mahmood, Tony Lugemwa, Patrick J Dillon

{"title":"Methamphetamine-Induced Wakefulness and Sleep Management: A Qualitative Analysis of Online Narratives.","authors":"Sanjaya Regmi, Satish K Kedia, Michael Schmidt, Asos Mahmood, Tony Lugemwa, Patrick J Dillon","doi":"10.1080/02791072.2023.2246458","DOIUrl":"10.1080/02791072.2023.2246458","url":null,"abstract":"While much attention has been given to methamphetamine's wake-promoting properties and the concept of using methamphetamine to increase energy, little is known about the ways people who use methamphetamine manage their use to pursue their functional goals or the challenges they encounter doing so. This qualitative study explores the experiences of people who used methamphetamine to manage wakefulness and reduce sleep as a means to achieve functional goals. We conducted a grounded theory analysis of 202 anonymous letters submitted to an online forum. Five themes emerged from this process: (1) Using methamphetamine to extend wakefulness and reduce the need for sleep; (2) Losing control over wakefulness and the need for sleep; (3) Managing wakefulness and the need for sleep while on methamphetamine; (4) Getting caught in a cycle of wakefulness and sleep; and (5) Sleep disruptions even after ceasing methamphetamine use. Participants believed methamphetamine was critical to meeting their functional goals, and they went to great lengths to try to manage the substance's ill effects. Thus, clients in treatment for methamphetamine use disorder may benefit from interventions addressing their underlying motivations and perceived associations between methamphetamine and meeting functional goals.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"595-602"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10021926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemsex and Harm Reduction Practices Among Men Who Have Sex with Men in Malaysia: Findings from a Qualitative Study. 马来西亚男男性行为者中的化学性行为和减低伤害做法：一项定性研究的结果。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-08-23 DOI: 10.1080/02791072.2023.2250342

Lindsay Palmer, Francesca Maviglia, Jeffrey A Wickersham, Antoine Khati, Olivia Kennedy, Nicholas M Copenhaver, Christopher Uyer, Mohd Akbar Ab Halim, Wan Mohd Ikhtiaruddin, Iskandar Azwa, Kamal Gautam, Roman Shrestha

{"title":"Chemsex and Harm Reduction Practices Among Men Who Have Sex with Men in Malaysia: Findings from a Qualitative Study.","authors":"Lindsay Palmer, Francesca Maviglia, Jeffrey A Wickersham, Antoine Khati, Olivia Kennedy, Nicholas M Copenhaver, Christopher Uyer, Mohd Akbar Ab Halim, Wan Mohd Ikhtiaruddin, Iskandar Azwa, Kamal Gautam, Roman Shrestha","doi":"10.1080/02791072.2023.2250342","DOIUrl":"10.1080/02791072.2023.2250342","url":null,"abstract":"Chemsex is a form of sexualized drug use commonly practiced among MSM with psychoactive substances, such as methamphetamine. While this phenomenon has gained global attention in the past two decades, there is a dearth of empirical data to inform culturally competent interventions. The current work investigates the socio-contextual factors related to chemsex and harm reduction practices among Malaysian MSM. Between February and August 2022, we conducted six online focus group sessions with Malaysian MSM who had engaged in chemsex during the previous 6 months (N = 22). We queried participants about perceived benefits and harms, harm reduction practices, and informational needs. Most participants' first chemsex experience occurred in a casual sexual encounter, often facilitated by mobile technology. Participants reported engaging in harm reduction practices before (e.g. medication reminders), during (e.g. peer support), and after (e.g. rest) chemsex. These findings have implications for future efforts to develop and implement tailored interventions to address the specific and acute needs of Malaysian MSM engaging in chemsex.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"585-594"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10884347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10200248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond Psilocybin: Reviewing the Therapeutic Potential of Other Serotonergic Psychedelics in Mental and Substance Use Disorders. 超越迷幻剂：回顾其他血清素能迷幻剂对精神障碍和药物使用障碍的治疗潜力。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-09-01 Epub Date: 2023-08-24 DOI: 10.1080/02791072.2023.2251133

Stanley Wong, An Yi Yu, Nicholas Fabiano, Ofer Finkelstein, Aryan Pasricha, Brett D M Jones, Joshua D Rosenblat, Daniel M Blumberger, Benoit H Mulsant, M Ishrat Husain

{"title":"Beyond Psilocybin: Reviewing the Therapeutic Potential of Other Serotonergic Psychedelics in Mental and Substance Use Disorders.","authors":"Stanley Wong, An Yi Yu, Nicholas Fabiano, Ofer Finkelstein, Aryan Pasricha, Brett D M Jones, Joshua D Rosenblat, Daniel M Blumberger, Benoit H Mulsant, M Ishrat Husain","doi":"10.1080/02791072.2023.2251133","DOIUrl":"10.1080/02791072.2023.2251133","url":null,"abstract":"There has been a resurgence of interest in the use of psychedelic therapies for several mental and substance use disorders. Psilocybin, a \"classic\" serotonergic psychedelic, has emerged as one of the primary compounds of interest in clinical research. While research on psilocybin's potential mental health benefits has grown, data on the safety and efficacy of other serotonergic psychedelics remain limited. A comprehensive scoping review on the use of mescaline, ibogaine, ayahuasca, N,N-dimethyltryptamine (DMT), and lysergic acid diethylamide (LSD) in the treatment of mental and substance disorders was conducted. Independent reviewers screened titles, abstracts, and full texts and conducted data extraction. Seventy-seven studies met the inclusion criteria. There were 43 studies of LSD, 24 studies of ayahuasca, 5 studies of DMT, 5 studies of ibogaine, and 5 studies of mescaline. Commonly reported benefits included improved mood and anxiety symptoms, improved insight, reduced substance use, improved relationships, and decreased vegetative symptoms. Commonly reported adverse effects were psychological, neurological, physical, and gastrointestinal in nature. Serious adverse events (homicide and suicide) were reported in published studies of LSD. In conclusion, there is only low-level evidence to support the safety and efficacy of non-psilocybin serotonergic psychedelics in individuals with mental and substance use disorders.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"513-529"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethical Issues in Treating Substance Use Disorders: Counselor Perspectives. 治疗药物使用障碍的伦理问题：咨询师的观点。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-08-30 DOI: 10.1080/02791072.2024.2394765

James L Sorensen, Caravella McCuistian, J Konadu Fokuo, Homero E Del Pino, Jaime Dumoit Smith, Sania Elahi, Emily A Arnold

{"title":"Ethical Issues in Treating Substance Use Disorders: Counselor Perspectives.","authors":"James L Sorensen, Caravella McCuistian, J Konadu Fokuo, Homero E Del Pino, Jaime Dumoit Smith, Sania Elahi, Emily A Arnold","doi":"10.1080/02791072.2024.2394765","DOIUrl":"10.1080/02791072.2024.2394765","url":null,"abstract":"Ethical issues arise frequently in the treatment of substance use disorders (SUD). Counselors need guidance to navigate ethical dilemmas but receive limited training in resolving ethical issues. To narrow the gap between the ethical dilemmas counselors face and their training, this qualitative study assessed ethical issues that counselors encounter, how they resolve them, and desired training. We conducted qualitative individual interviews with 20 front-line counselors working in two SUD treatment programs, presenting brief vignettes that depicted the ethics code of the national organization representing SUD counselors. The interviews asked open-ended questions about how counselors dealt with issues and their ideas for future ethics training. All participants had encountered ethical dilemmas. Areas of concern included confidentiality and privacy, mandatory reporting, fairness/equity, client-counselor boundaries, tensions between workplace and client welfare, and meeting clients' complex needs. Ways participants resolved ethical issues included consultations, using direct approaches to resolve ethical dilemmas, and commitment to providing client-centered care. Useful training in the workplace was sparse. Participants expressed needs for ongoing support to resolve workplace ethical dilemmas. Although the importance of ethical issues is widely acknowledged in treating SUD, this study underscores the need for ongoing and interactive training and supervision about ethical issues.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Associated with an Increased Risk of Opioid Misuse Among Patients with Non-Cancer Pain in Malaysian Pain Clinic Settings. 马来西亚疼痛诊所非癌症疼痛患者滥用阿片类药物风险增加的相关因素。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-08-05 DOI: 10.1080/02791072.2024.2387602

Asween R Sani, Che Suraya Zin

{"title":"Factors Associated with an Increased Risk of Opioid Misuse Among Patients with Non-Cancer Pain in Malaysian Pain Clinic Settings.","authors":"Asween R Sani, Che Suraya Zin","doi":"10.1080/02791072.2024.2387602","DOIUrl":"https://doi.org/10.1080/02791072.2024.2387602","url":null,"abstract":"This study examined the factors associated with a high risk of opioid misuse among patients receiving opioid treatment for their non-cancer pain in Malaysian pain clinics. The Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R), a validated instrument for predicting the risk of aberrant drug-related behaviors, were used as a proxy to indicate risk of opioid misuse. Data analysis was stratified into high-risk and low-risk patient groups. Patient factors assessed included pain intensity, pain interference with daily activities, and health-related quality of life. Prescription opioid exposure was examined via patient medical and prescription records review. Among the 61 patients recruited, 62.3% scored ≥18 on the SOAPP-R, which indicates a high risk for opioid misuse. Factors associated with a high risk of opioid misuse were found to be high level of pain interference with daily activities, poorer mental health, and younger age. High-risk patients were found to be prescribed a lower mean daily opioid dose of <20 mg/day compared to low-risk patients (20-49 mg/day). This highlights the need for further research to distinguish aberrant drug-related behaviors due to inadequate pain management from that of actual prescription opioid misuse among non-cancer pain patients attending pain clinics.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141889509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magic of the Mushrooms: Effects of Psilocybin Decriminalization. 蘑菇的魔力：迷幻药非刑罪化的影响。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2024-07-10 DOI: 10.1080/02791072.2024.2376755

Ashutosh Bhave

{"title":"Magic of the Mushrooms: Effects of Psilocybin Decriminalization.","authors":"Ashutosh Bhave","doi":"10.1080/02791072.2024.2376755","DOIUrl":"https://doi.org/10.1080/02791072.2024.2376755","url":null,"abstract":"In the past few years, psilocybin, a psychedelic compound found in \"magic mushrooms\" (psilocybin mushrooms), has undergone decriminalization in numerous cities across the US and has been legalized in Oregon and Colorado. Proponents of psilocybin decriminalization have emphasized its therapeutic potential in treating mental health disorders. Furthermore, psilocybin mushrooms are considered the safest psychedelic option, with lower potency and a reduced risk of overdoses and emergency hospitalizations compared to other prevalent psychedelics, such as LSD (lysergic acid diethylamide) and MDMA (3,4-methylenedioxymethamphetamine). We analyzed the impact of psilocybin reforms on public interest in psilocybin, as well as their cross-commodity effects on LSD and MDMA, utilizing extensive web-based search data. We observe a significant increase in psilocybin search volume and a notable reduction in search volume associated with LSD and MDMA. Our results are consistent nationwide across states, irrespective of their stance on psilocybin reforms. The shift in public interest toward psilocybin, which is considered the safest psychedelic, away from LSD and MDMA, carries positive implications for public health.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0