Journal of psychoactive drugs最新文献_第6页

Patterns of Opioid and NSAID Use in Saudi Arabia from 2010 to 2020. 2010年至2020年沙特阿拉伯阿片类药物和非甾体抗炎药使用模式

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-01-06 DOI: 10.1080/02791072.2025.2449912

Abdullah U Althemery, Mohammed Alsubaie, Hamoud Alharbi, Ammar Alqahtani, Ghazi Alsubaie, Abdulrahman Alotaibi

{"title":"Patterns of Opioid and NSAID Use in Saudi Arabia from 2010 to 2020.","authors":"Abdullah U Althemery, Mohammed Alsubaie, Hamoud Alharbi, Ammar Alqahtani, Ghazi Alsubaie, Abdulrahman Alotaibi","doi":"10.1080/02791072.2025.2449912","DOIUrl":"10.1080/02791072.2025.2449912","url":null,"abstract":"The use of analgesics has increased globally over the last three decades. Prescription drug abuse has increased significantly, and opioids have been identified as causing further harm to the world. This study explored the utilization and expenditure associated with opioids and non-steroidal anti-inflammatory drugs (NSAIDs) from 2010 to 2020 in Saudi Arabia. This descriptive time-series analysis was conducted in two major hospitals in Riyadh, Saudi Arabia, between 2010 and 2020. Data were collected from the inpatients, outpatients, and emergency departments of the Security Force Hospital and King Fahad Medical City in Riyadh. The analgesics examined included celecoxib, diclofenac sodium, ibuprofen, lornoxicam, mefenamic acid, paracetamol, and tramadol. A total of 48,106 analgesics were prescribed during this period. Peak utilization of all opioid and NSAID products occurred in 2019. Paracetamol accounted for 29.33% of all prescriptions. However, in 2020, tramadol prescriptions were the highest, accounting for 2,798 prescriptions. The average price per prescription unit decreased between 2012 and 2019 and increased in 2020 from SAR 0.87 to SAR 4.50 per unit. This study's findings can guide healthcare policy and practices and enhance the quality of treatment for patients who require analgesic treatment.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"194-199"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What Differentiates Dropping Out from Remaining in a Brief Intervention for Problematic and Dependent Methamphetamine Users? 对有问题和依赖的甲基苯丙胺使用者来说，退出和留在短暂干预中有什么区别？

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-02-12 DOI: 10.1080/02791072.2025.2464792

Magdalena Maria Rowicka

{"title":"What Differentiates Dropping Out from Remaining in a Brief Intervention for Problematic and Dependent Methamphetamine Users?","authors":"Magdalena Maria Rowicka","doi":"10.1080/02791072.2025.2464792","DOIUrl":"10.1080/02791072.2025.2464792","url":null,"abstract":"Amphetamine-type stimulants (including methamphetamine) are the second most frequently used illicit substances, after cannabis worldwide. The treatment dropout rate is higher among stimulant users than in the case of any other substance. Younger age, greater severity of the substance use disorder, lower motivation to change, and greater mental health problems are among the predictors of treatment dropout. Research showed that a brief intervention with cognitive-behavioral strategies and motivational interviewing addresses the most paramount issues. This paper investigates the differences between the individuals who dropped out and those who remained in the intervention. Twenty-one participants dropped out from the intervention, and 32 remained in the intervention. The analyzed variables included illicit substance use, severity of methamphetamine dependence, alcohol use (with distinction between spirits, wine and beer), motivation to change (readiness for change questionnaire), depressive and generalized anxiety symptoms, life satisfaction and self-efficacy. The results showed no differences between the two investigated groups except for beer consumed 30 days before the intervention. (the drop-out group consumed statistically more beer). The results showed that there is a need for further investigation since none of the substance use or person-specific characteristics differentiated dropping out from remaining in the intervention.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"217-225"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Approach Without Liking: The Effects of Smoking-Related Settings on Implicit Liking Attitudes and Approach Tendencies Toward Smoking. 不喜欢的方式：吸烟相关环境对隐性喜欢态度和吸烟接近倾向的影响。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-02-06 DOI: 10.1080/02791072.2025.2462004

Haide Chen, Enjin Zheng, Keying Lai, Boqiang Zhao, Tingting Wei, Lingfeng Gao, Weijian Li

{"title":"Approach Without Liking: The Effects of Smoking-Related Settings on Implicit Liking Attitudes and Approach Tendencies Toward Smoking.","authors":"Haide Chen, Enjin Zheng, Keying Lai, Boqiang Zhao, Tingting Wei, Lingfeng Gao, Weijian Li","doi":"10.1080/02791072.2025.2462004","DOIUrl":"10.1080/02791072.2025.2462004","url":null,"abstract":"Little is known about whether smokers consistently show implicit liking attitudes and approach tendencies toward smoking in various smoking-related settings. This study aimed to examine the effects of static object and dynamic action cues associated with cigarettes on the liking and approach components of implicit attitudes toward smoking. Three experiments were conducted using a modified paradigm of the Brief Implicit Association Test (BIAT). In each experiment, participants were required to complete both the liking-BIAT and approach-BIAT. Experiment 1 showed that smokers exhibited fewer negative attitudes and more approach tendencies toward smoking than nonsmokers. Experiment 2 showed that neither liking nor approach tendencies of implicit attitudes toward smoking differed significantly in smoking-related and neutral situations among smokers. Experiment 3 showed that smokers exhibited more approach tendencies toward smoking under dynamic action cues associated with cigarettes than that under static object cues, whereas implicit liking attitudes were not significantly different under these two settings. The present results suggested that the approach component of implicit attitudes was more sensitive to smoking-related settings, including cues of cigarette-offering action, than implicit liking attitudes, which increased the understanding of distinct activation mechanisms of different components of implicit attitudes toward smoking.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"351-360"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics of Health Professions Students with Nitrous Oxide Use Disorder. 卫生专业学生氧化亚氮使用障碍的临床特点

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-02-03 DOI: 10.1080/02791072.2025.2461992

Bernard Angerville, Alexandre Szusterman, Lisa Blecha, Amine Benyamina, Mickaël Naassila, Alain Dervaux

{"title":"Clinical Characteristics of Health Professions Students with Nitrous Oxide Use Disorder.","authors":"Bernard Angerville, Alexandre Szusterman, Lisa Blecha, Amine Benyamina, Mickaël Naassila, Alain Dervaux","doi":"10.1080/02791072.2025.2461992","DOIUrl":"10.1080/02791072.2025.2461992","url":null,"abstract":"Recreational use and misuse of nitrous oxide (N2O) have increased in recent years among young people. The objective of present study was to assess the frequency and the clinical characteristics of N2O use disorder (NUD) in a sample of health professions students. An online survey was distributed to health professions students. Age; sex; frequency (day/week/month/year/lifetime) of N2O use, DSM-5 criteria for NUD; history of mental health treatment; and current use of antidepressant medication were systematically collected. All participants completed the French version of Alcohol Use Disorders Identification Test (AUDIT), and Cannabis Abuse Screening Test (CAST). A total of 2067 students (mean age 21.7 ± 2.6 years, 74.9% female) completed the survey. A total of 38.2% (n = 790) reported lifetime N2O use. Among the 6.6% (n = 137) who fulfilled the DSM-5 criteria for current NUD, 5.5% (n = 114) had mild disorder, 0.8% (n = 16) had moderate disorder (n = 16) and 0.3% (n = 7) had severe disorder. Participants with NUD more frequently reported AUDIT scores > 12 (suggesting alcohol dependence), blackouts, a history of mental health treatment, and current use of antidepressants than did those without NUD. Longitudinal studies using structured interviews are needed to investigate potential associations between NUD and alcohol use disorders or psychiatric disorders in the general population.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"345-350"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Psilocybin Experience Gone Wrong: The Importance of Psychedelic Assisted Psychotherapy. 裸盖菇素的错误体验：迷幻辅助心理治疗的重要性。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-01-07 DOI: 10.1080/02791072.2025.2449918

Fernando Espi Forcen

引用次数: 0

Health-Promoting Behaviors in Male Patients with Opioid Use Disorder: An Exploratory Study. 阿片类药物使用障碍男性患者促进健康行为的探索性研究

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2024-12-26 DOI: 10.1080/02791072.2024.2446454

Vinit Patel, Parvender Singh Negi, Rekha Pal Shah, Anju Dhawan, Siddharth Sarkar

{"title":"Health-Promoting Behaviors in Male Patients with Opioid Use Disorder: An Exploratory Study.","authors":"Vinit Patel, Parvender Singh Negi, Rekha Pal Shah, Anju Dhawan, Siddharth Sarkar","doi":"10.1080/02791072.2024.2446454","DOIUrl":"10.1080/02791072.2024.2446454","url":null,"abstract":"Health-promoting lifestyle and behaviors play a crucial role in the prognosis of an illness as well as in healing. With the significant global burden of unhealthy lifestyle choices, their impact on individuals with substance use disorders can be particularly burdensome, hampering overall well-being. This study assesses health-promoting lifestyle and behavior and dietary habits among treatment-seeking male patients with opioid use disorders. This cross-sectional observational study enrolled 179 male patients undergoing treatment for opioid use disorder in a treatment center dedicated to addiction services. Data were collected using a semi-structured questionnaire, the Health-Promoting Lifestyle Profile II (HPLP-II), the Maudsley Addiction Profile, and a food frequency questionnaire adapted for the north Indian diet. The mean age of the sample was 31.5 years, and almost half of the participants were underweight (n = 86, 48.0%). Participants often engaged in some health-promoting behaviors, such as nutrition, stress management, spiritual growth, and interpersonal relations; and generally neglected aspects of physical activity and health responsibility. Over half of the participants consumed less energy than recommended, while about a fourth failed to meet daily protein intake recommendations. The study underscores the need to incorporate lifestyle and dietary assessment and modification alongside psycho-pharmacological treatment for patients with opioid use disorders.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"200-208"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Death Anxiety Among Users and Non-Users of Psychedelics. 致幻剂使用者和非使用者的死亡焦虑。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-01-10 DOI: 10.1080/02791072.2025.2451035

Ana Cláudia Mesquita Garcia, Lucas Oliveira Maia, Everson Meireles, Denismar Alves Nogueira, Luís Fernando Tófoli

{"title":"Death Anxiety Among Users and Non-Users of Psychedelics.","authors":"Ana Cláudia Mesquita Garcia, Lucas Oliveira Maia, Everson Meireles, Denismar Alves Nogueira, Luís Fernando Tófoli","doi":"10.1080/02791072.2025.2451035","DOIUrl":"10.1080/02791072.2025.2451035","url":null,"abstract":"This study is a survey-type, cross-sectional study conducted in Brazil (n = 517), with online data collection taking place from April to June 2022. The main objective of this study was to evaluate the death anxiety in users and non-users of psychedelics. To this end, we also assessed the validity and reliability of the Death Anxiety Scale in Brazil. The following instruments were used for data collection: a questionnaire for sociodemographic characterization, Death Anxiety Scale, Death Transcendence Scale, and Spiritual Well-Being Scale. Our main results indicated the following: 1) increased death anxiety is associated with never or almost never having used psychedelics; 2) death transcendence, especially creative and religious factors, was the only constant variable in all the explanatory models of the variation in death anxiety; 3) there is a negative relationship between death anxiety and mystical and religious factors of death transcendence. We interpret these results as follows: it's not psychedelics that reduce death anxiety - psychedelics can favor the experience of transcending death. And it's the possibility of transcending death, (idea of continuity beyond physical death, taking both spiritual and symbolic forms) that helps reduce death anxiety. These findings offer valuable insights into the role of psychedelics in human mortality perception.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"254-264"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tripping into Treatment: Comparing Initial and Current Motivations for Psychedelic Use. 进入治疗：比较最初和现在使用迷幻药的动机。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-02-05 DOI: 10.1080/02791072.2025.2461999

Daniel J Kruger, Jeff Albrecht, Jacob S Aday, Julie Barron, Moss Herberholz, Kevin F Boehnke

{"title":"Tripping into Treatment: Comparing Initial and Current Motivations for Psychedelic Use.","authors":"Daniel J Kruger, Jeff Albrecht, Jacob S Aday, Julie Barron, Moss Herberholz, Kevin F Boehnke","doi":"10.1080/02791072.2025.2461999","DOIUrl":"10.1080/02791072.2025.2461999","url":null,"abstract":"Psychedelic drugs are currently being explored for their therapeutic potential for a variety of health conditions. The recent increased public interest in psychedelics necessitates empirical investigation into motivations for use among users as well as how motivations may change over time. We asked a large sample of participants reporting naturalistic psychedelic use (N = 1221) about their motivations for using psychedelics initially (i.e. their first time) as well as currently. We found that motivations for psychedelic use change substantially over time, with initial use typically for recreation or exploration, and later use more for therapeutic or personal growth reasons, including managing mental health conditions, growing spiritually, connecting with nature, improving creativity, and managing trauma. These results highlight the distinct and shifting motivations for engaging in psychedelic use. Although the study was limited by a retrospective design, it is the first to show that motivations for using psychedelics may change over time, with initial use focused on recreation and curiosity but subsequent use more motivated by self-improvement (e.g. enhancing relationships and health). Future prospective designs and qualitative interviews may aid in further elucidating the mechanisms underlying these shifts in motivations over time.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"298-304"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug use Risks in Portuguese Rural vs Urban Environments: Harm Reduction Challenges in a Progressive Drug Policy Setting. 葡萄牙农村与城市环境中的药物使用风险：在进步的药物政策设置中减少危害的挑战。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-01-21 DOI: 10.1080/02791072.2025.2449913

Marta Sofia de Sousa Pinto, Cristiana Vale Pires, Helena Maria Ribeiro Moura de Carvalho, Catarina Pinto Pereira, Gabriela Almeida Pinto da Silva, Ludmila de Jesus Grilo Carapinha, Filipa Oliveira Gonçalves, Helena Valente

{"title":"Drug use Risks in Portuguese Rural vs Urban Environments: Harm Reduction Challenges in a Progressive Drug Policy Setting.","authors":"Marta Sofia de Sousa Pinto, Cristiana Vale Pires, Helena Maria Ribeiro Moura de Carvalho, Catarina Pinto Pereira, Gabriela Almeida Pinto da Silva, Ludmila de Jesus Grilo Carapinha, Filipa Oliveira Gonçalves, Helena Valente","doi":"10.1080/02791072.2025.2449913","DOIUrl":"10.1080/02791072.2025.2449913","url":null,"abstract":"Portugal is commonly recognized as one of the best drug policy examples in the world. Nonetheless, contrasts between drug use risks in rural vs urban settings in the country is an understudied topic, even if its specific challenges are commonly affirmed, both by professionals and people who use drugs (PWUD). The aim of this study was to compare rural and urban environments concerning socio-sanitary services availability; illegal drugs availability; risk behaviors related to drug use; stigma associated with illicit drug use; and social support. Additionally, specific harm reduction challenges and recommendations for improvement were explored. A qualitative study with two focus groups involving people who use drugs, outreach workers and local decision-makers was conducted. Distinct scenarios and challenges in both settings were found: In large cities, a significantly higher specialized service coverage than in rural areas was described. In rural settings, a higher number of drug-related risks, higher levels of stigma and lower availability of human and material resources were mentioned, although being associated with higher levels of informal social support and more proximal relationships with harm reduction teams. This study emphasizes the need for a harm reduction paradigm strongly focused on environmental risk determinants, as much as in individual ones.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"316-324"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex Differences in Religious Beliefs Before and After an Entity Encounter During an Ayahuasca Experience. 死藤水体验中实体接触前后宗教信仰的性别差异。

IF 2.4 4区医学

Journal of psychoactive drugs Pub Date : 2026-07-01 Epub Date: 2025-02-13 DOI: 10.1080/02791072.2025.2462008

Yitong Xin, Roland R Griffiths, Alan K Davis

{"title":"Sex Differences in Religious Beliefs Before and After an Entity Encounter During an Ayahuasca Experience.","authors":"Yitong Xin, Roland R Griffiths, Alan K Davis","doi":"10.1080/02791072.2025.2462008","DOIUrl":"10.1080/02791072.2025.2462008","url":null,"abstract":"An interesting aspect of entity encounters during psychedelic experiences is their ability to transform one's religious beliefs. However, little is known about sex differences in these transformations. This study investigates sex differences in changes in religious beliefs before and after an entity encounter among ayahuasca users. Data were collected via an anonymous Internet-based survey (N = 415; Mage = 38.53, SD = 11.39; male = 60.5%). Descriptive analyses, binary logistic regression, and two-proportion z-tests were conducted. Before the entity encounter, males were significantly more likely to identify as atheists (OR = 2.889, p = .001) and less likely to identify as having religious beliefs (OR = 0.453, p < .001) compared to females. After the entity encounter, no significant sex differences in religious beliefs were found (ps >0.05). Comparing changes before and after the experience, both sex groups showed decreases in atheism and agnosticism and increases in religious beliefs, with males exhibiting larger changes. Specifically, the proportion of males identifying as religious significantly increased from before to after the entity encounter (z = 3.49, p < .001), whereas the increase for females was not statistically significant. Findings suggest sex is associated with perceived changes in religious beliefs among ayahuasca users reporting an entity encounter, highlighting the importance of considering sex in psychedelic research and its impact on spirituality and related outcomes.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"246-253"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0