Journal of psychoactive drugs最新文献

Experimental Test of Perceptions of Psychedelics by Therapeutic and Recreational Use.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-22 DOI: 10.1080/02791072.2025.2452231

Mackenzie T Kiniry, Renee E Magnan, Sarah N Elder, Benjamin O Ladd

{"title":"Experimental Test of Perceptions of Psychedelics by Therapeutic and Recreational Use.","authors":"Mackenzie T Kiniry, Renee E Magnan, Sarah N Elder, Benjamin O Ladd","doi":"10.1080/02791072.2025.2452231","DOIUrl":"https://doi.org/10.1080/02791072.2025.2452231","url":null,"abstract":"Recent research on the potential therapeutic value of psychedelic substances has led to changes in media representation and drug policy in some U.S. states. Yet, little is known about lay perceptions of these substances. The current study aimed to describe health perceptions of psychedelic substances, test differences in perceptions of therapeutic vs. recreational use of psychedelic substances, and determine if such perceptions vary by use experience. Participants (N = 309) completed an online within-subjects experiment in which they responded to measures of positive and negative perceptions of therapeutic and recreational use of psychedelics. Endorsement of positive and negative health perceptions of psychedelics was moderate to strong. Recreational use was perceived as having more negative health consequences, while therapeutic use was perceived as having more positive health consequences. Participants who reported lifetime psychedelic use (40.7%) perceived both recreational and therapeutic uses as having more positive health consequences, and this pattern was consistent across most perception domains. The outcomes suggest that public perceptions of use may change based on reason for use. This information may aid in filling current gaps in knowledge and identifying potential targets for public health communications, and such approaches may benefit from considering prior use experience.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug use Risks in Portuguese Rural vs Urban Environments: Harm Reduction Challenges in a Progressive Drug Policy Setting. 葡萄牙农村与城市环境中的药物使用风险：在进步的药物政策设置中减少危害的挑战。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-21 DOI: 10.1080/02791072.2025.2449913

Marta Sofia de Sousa Pinto, Cristiana Vale Pires, Helena Maria Ribeiro Moura de Carvalho, Catarina Pinto Pereira, Gabriela Almeida Pinto da Silva, Ludmila de Jesus Grilo Carapinha, Filipa Oliveira Gonçalves, Helena Valente

{"title":"Drug use Risks in Portuguese Rural vs Urban Environments: Harm Reduction Challenges in a Progressive Drug Policy Setting.","authors":"Marta Sofia de Sousa Pinto, Cristiana Vale Pires, Helena Maria Ribeiro Moura de Carvalho, Catarina Pinto Pereira, Gabriela Almeida Pinto da Silva, Ludmila de Jesus Grilo Carapinha, Filipa Oliveira Gonçalves, Helena Valente","doi":"10.1080/02791072.2025.2449913","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449913","url":null,"abstract":"Portugal is commonly recognized as one of the best drug policy examples in the world. Nonetheless, contrasts between drug use risks in rural vs urban settings in the country is an understudied topic, even if its specific challenges are commonly affirmed, both by professionals and people who use drugs (PWUD). The aim of this study was to compare rural and urban environments concerning socio-sanitary services availability; illegal drugs availability; risk behaviors related to drug use; stigma associated with illicit drug use; and social support. Additionally, specific harm reduction challenges and recommendations for improvement were explored. A qualitative study with two focus groups involving people who use drugs, outreach workers and local decision-makers was conducted. Distinct scenarios and challenges in both settings were found: In large cities, a significantly higher specialized service coverage than in rural areas was described. In rural settings, a higher number of drug-related risks, higher levels of stigma and lower availability of human and material resources were mentioned, although being associated with higher levels of informal social support and more proximal relationships with harm reduction teams. This study emphasizes the need for a harm reduction paradigm strongly focused on environmental risk determinants, as much as in individual ones.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consuming and Thinking About Nangs: A Survey of Nitrous Oxide Use, Knowledge, Attitudes and Perceptions in Aotearoa New Zealand. 消费和思考Nangs：一项调查一氧化二氮的使用，知识，态度和看法在新西兰奥特罗阿。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-21 DOI: 10.1080/02791072.2025.2452224

Jai Whelan, Taylah John, Rose Crossin, Ryan D Ward

{"title":"Consuming and Thinking About Nangs: A Survey of Nitrous Oxide Use, Knowledge, Attitudes and Perceptions in Aotearoa New Zealand.","authors":"Jai Whelan, Taylah John, Rose Crossin, Ryan D Ward","doi":"10.1080/02791072.2025.2452224","DOIUrl":"https://doi.org/10.1080/02791072.2025.2452224","url":null,"abstract":"Non-medical use of nitrous oxide (N2O) is becoming increasingly popular globally, yet little data exists regarding N2O in Aotearoa New Zealand. We aimed to explore patterns of use and harm in those who consume N2O in Aotearoa, and related knowledge, perceptions and attitudes of those with and without N2O experience. A convenience sample of people with N2O experience (n = 466) and without (n = 510) completed an online survey about N2O. Most with N2O experience reported infrequent and low-dose consumption. Harm reduction behaviors were utilized by most consumers, and reports of adverse effects were relatively low. Self-reported acute or chronic harm (primarily psychological) was reported by only 5.8% of the N2O sample, whilst 9.2% reported ever experiencing persistent numbness (5.2% in the past 12 months). Self-reported knowledge about N2O varied and was greater in those with N2O experience. N2O knowledge was generally poor, although more accurate in those with N2O experience. Attitudes generally differed between those with and without N2O experience, and perceived harmfulness and experience significantly contributed to attitudes regarding N2O legality. Findings underscore the relative safety of N2O when used recreationally, but also highlight the need for greater drug education around potential risks of N2O use and harm reduction.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing Dual Dependencies: A Case Study of Concurrent Low-Dose Buprenorphine Induction and Rapid Phenobarbital Taper. 管理双重依赖：同时低剂量丁丙诺啡诱导和快速苯巴比妥逐渐减少的案例研究。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-14 DOI: 10.1080/02791072.2024.2446448

Brent Schnipke, Gayane Archer, Veronika Hanko, Brandon Hamm

引用次数: 0

Death Anxiety Among Users and Non-Users of Psychedelics. 致幻剂使用者和非使用者的死亡焦虑。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-10 DOI: 10.1080/02791072.2025.2451035

Ana Cláudia Mesquita Garcia, Lucas Oliveira Maia, Everson Meireles, Denismar Alves Nogueira, Luís Fernando Tófoli

{"title":"Death Anxiety Among Users and Non-Users of Psychedelics.","authors":"Ana Cláudia Mesquita Garcia, Lucas Oliveira Maia, Everson Meireles, Denismar Alves Nogueira, Luís Fernando Tófoli","doi":"10.1080/02791072.2025.2451035","DOIUrl":"https://doi.org/10.1080/02791072.2025.2451035","url":null,"abstract":"This study is a survey-type, cross-sectional study conducted in Brazil (n = 517), with online data collection taking place from April to June 2022. The main objective of this study was to evaluate the death anxiety in users and non-users of psychedelics. To this end, we also assessed the validity and reliability of the Death Anxiety Scale in Brazil. The following instruments were used for data collection: a questionnaire for sociodemographic characterization, Death Anxiety Scale, Death Transcendence Scale, and Spiritual Well-Being Scale. Our main results indicated the following: 1) increased death anxiety is associated with never or almost never having used psychedelics; 2) death transcendence, especially creative and religious factors, was the only constant variable in all the explanatory models of the variation in death anxiety; 3) there is a negative relationship between death anxiety and mystical and religious factors of death transcendence. We interpret these results as follows: it's not psychedelics that reduce death anxiety - psychedelics can favor the experience of transcending death. And it's the possibility of transcending death, (idea of continuity beyond physical death, taking both spiritual and symbolic forms) that helps reduce death anxiety. These findings offer valuable insights into the role of psychedelics in human mortality perception.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Index of Cannabis Equivalence (ICE): A User-Centered Approach to Standardization of Cannabis Dose-Response. 大麻等效指数（ICE）：以用户为中心的大麻剂量反应标准化方法。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-09 DOI: 10.1080/02791072.2025.2449932

Michelle St Pierre, Stacey Squires, Sarah Daniels, Tatiana Sanchez, Zach Walsh

{"title":"The Index of Cannabis Equivalence (ICE): A User-Centered Approach to Standardization of Cannabis Dose-Response.","authors":"Michelle St Pierre, Stacey Squires, Sarah Daniels, Tatiana Sanchez, Zach Walsh","doi":"10.1080/02791072.2025.2449932","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449932","url":null,"abstract":"The increasing acceptance of cannabis use, and policy changes in several jurisdictions has led researchers and public health experts to call for a standard cannabis dose. Standard dosing units are useful tools for regulation, substance use guidelines, data collection, consistency of research, as a means of communicating low-risk recommendations and dose-related effects, and for self-monitoring. Efforts to standardize cannabis dose have focused on cannabinoid content without considering tolerance or mode. Cannabis users with diverse motivations for use and varying experience rated low, medium, and high doses across seven modes of use. The participants (N = 1368; 42% female) were 18-93 years of age (M = 31.64, SD = 14.70) who had a cannabis use history. The Index of Cannabis Equivalence (ICE) identified the following low-dose cannabis equivalencies: two puffs on a joint, pipe, herbal or concentrate vaporizer is equivalent to one hit on a bong, a 5 mg/THC edible, and ¼ dab of a concentrate. These findings are based on responses from users with lower tolerance, which may limit generalizability to those with higher tolerance. The ICE proposes standardized cannabis doses through user-derived ratings across different administration routes. The meaningful standardization of units of cannabis products in a manner similar to what has been achieved for alcohol represents a valuable step in establishing standard doses across different modes of cannabis administration.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-6"},"PeriodicalIF":2.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychotic-Like Experiences in Young Recreational Users of Ketamine: A Case Study. 青少年娱乐性氯胺酮使用者的精神病样经验：个案研究。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-08 DOI: 10.1080/02791072.2025.2449909

Valerio Ricci, Domenico De Berardis, Sheikh Shoib, Giovanni Martinotti, Giuseppe Maina

{"title":"Psychotic-Like Experiences in Young Recreational Users of Ketamine: A Case Study.","authors":"Valerio Ricci, Domenico De Berardis, Sheikh Shoib, Giovanni Martinotti, Giuseppe Maina","doi":"10.1080/02791072.2025.2449909","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449909","url":null,"abstract":"This study explores the psychotic-like experiences (PLEs) associated with recreational ketamine use among young adults. Ketamine, initially introduced as an anesthetic, is now widely used recreationally for its dissociative effects, raising concerns about its impact on mental health. Ten participants aged 18-24, who used ketamine recreationally multiple times a week, were assessed using the Community Assessment of Psychic Experiences (CAPE-42). Results showed a significant positive correlation between the frequency of ketamine use and PLEs, with no significant impact from other substances like THC, MDMA, and alcohol. These findings confirm ketamine's potential to induce psychotic-like symptoms by antagonizing NMDA receptors, similar to schizophrenia. The study underscores the need for preventive measures and targeted interventions to address the mental health risks of frequent ketamine use, particularly among young adults. However, limitations such as the small sample size and reliance on self-reported data suggest that further research is needed to establish causality and examine long-term effects. Overall, this study highlights the significant association between recreational ketamine use and increased PLEs, emphasizing the importance of early detection and intervention strategies.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Psilocybin Experience Gone Wrong: The Importance of Psychedelic Assisted Psychotherapy. 裸盖菇素的错误体验：迷幻辅助心理治疗的重要性。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-07 DOI: 10.1080/02791072.2025.2449918

Fernando Espi Forcen

引用次数: 0

Ketamine-Assisted Psychotherapy for Antisocial Personality Disorder: A Case Report. 氯胺酮辅助治疗反社会型人格障碍1例报告。

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-07 DOI: 10.1080/02791072.2025.2449911

Matthew R Hicks, Heather Zwickey, Ryan Bradley

引用次数: 0

Patterns of Opioid and NSAID Use in Saudi Arabia from 2010 to 2020. 2010年至2020年沙特阿拉伯阿片类药物和非甾体抗炎药使用模式

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-01-06 DOI: 10.1080/02791072.2025.2449912

Abdullah U Althemery, Mohammed Alsubaie, Hamoud Alharbi, Ammar Alqahtani, Ghazi Alsubaie, Abdulrahman Alotaibi

{"title":"Patterns of Opioid and NSAID Use in Saudi Arabia from 2010 to 2020.","authors":"Abdullah U Althemery, Mohammed Alsubaie, Hamoud Alharbi, Ammar Alqahtani, Ghazi Alsubaie, Abdulrahman Alotaibi","doi":"10.1080/02791072.2025.2449912","DOIUrl":"https://doi.org/10.1080/02791072.2025.2449912","url":null,"abstract":"The use of analgesics has increased globally over the last three decades. Prescription drug abuse has increased significantly, and opioids have been identified as causing further harm to the world. This study explored the utilization and expenditure associated with opioids and non-steroidal anti-inflammatory drugs (NSAIDs) from 2010 to 2020 in Saudi Arabia. This descriptive time-series analysis was conducted in two major hospitals in Riyadh, Saudi Arabia, between 2010 and 2020. Data were collected from the inpatients, outpatients, and emergency departments of the Security Force Hospital and King Fahad Medical City in Riyadh. The analgesics examined included celecoxib, diclofenac sodium, ibuprofen, lornoxicam, mefenamic acid, paracetamol, and tramadol. A total of 48,106 analgesics were prescribed during this period. Peak utilization of all opioid and NSAID products occurred in 2019. Paracetamol accounted for 29.33% of all prescriptions. However, in 2020, tramadol prescriptions were the highest, accounting for 2,798 prescriptions. The average price per prescription unit decreased between 2012 and 2019 and increased in 2020 from SAR 0.87 to SAR 4.50 per unit. This study's findings can guide healthcare policy and practices and enhance the quality of treatment for patients who require analgesic treatment.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-6"},"PeriodicalIF":2.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0