Journal of psychoactive drugs最新文献_第2页

Prevalence and Patterns of Cannabis Product Adulteration: An Analysis of WEDINOS Data.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-19 DOI: 10.1080/02791072.2025.2478087

Simon Erridge, Martin Hall, Mikael H Sodergren

引用次数: 0

Psychedelic Use and Behavioral Addictions.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-15 DOI: 10.1080/02791072.2025.2474244

Trey Brasher, David Rosen, Marcello Spinella

{"title":"Psychedelic Use and Behavioral Addictions.","authors":"Trey Brasher, David Rosen, Marcello Spinella","doi":"10.1080/02791072.2025.2474244","DOIUrl":"https://doi.org/10.1080/02791072.2025.2474244","url":null,"abstract":"Recent clinical trials on classic psychedelics for depression and anxiety have raised questions about their potential to treat other psychiatric conditions. Evidence from pre-clinical and clinical research suggests psychedelics may help with substance use disorders, with ongoing registered trials. Behavioral addictions, sharing features with substance addictions, may also respond to psychedelic treatment. This study examined self-reported symptoms of problem gambling, sexual addiction, compulsive buying, and eating disorders in a community sample (N = 1107), alongside measures of well-being (self-transcendence, personal growth, depression/anxiety, etc.), and use of psychedelics and other psychoactive drugs. Significant positive correlations emerged among well-being measures and among behavioral addiction symptoms, with inverse correlations between well-being and behavioral addictions. Psychedelic users reported greater well-being and lower behavioral addiction symptoms, even after controlling for demographics and other drug use. Principal components analysis showed that behavioral addictions formed a single factor, which was combined into a composite score. Multiple regression analyses revealed that major stimulant, alcohol, and nicotine vaping use predicted higher behavioral addiction scores, while psychedelic use uniquely predicted lower scores. These findings suggest psychedelics may aid in treating behavioral addictions. A controlled pilot study or clinical trial is warranted to explore this therapeutic potential further.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-14"},"PeriodicalIF":2.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combat Veterans' Experiences of Moral Injury, Cannabis Use Disorder and the Process of Meaning-Making: A Mixed Methods Study.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-14 DOI: 10.1080/02791072.2025.2479100

Adi Loewenstein, Ariel Asper, Daniel Feingold

{"title":"Combat Veterans' Experiences of Moral Injury, Cannabis Use Disorder and the Process of Meaning-Making: A Mixed Methods Study.","authors":"Adi Loewenstein, Ariel Asper, Daniel Feingold","doi":"10.1080/02791072.2025.2479100","DOIUrl":"https://doi.org/10.1080/02791072.2025.2479100","url":null,"abstract":"Combat veterans are highly inclined to develop substance use disorders, including Cannabis Use Disorder (CUD), with emerging evidence suggesting that combat related Potentially Morally Injurious Events (PMIEs) may increase proneness to CUD. To explore the moderating role of time since release from military duty, mixed methodology was applied. In a quantitative study, 322 Israeli cannabis-using male combat veterans filled out validated self-report questionnaires assessing PMIEs, CUD and time since release from military duty. Results indicate that self-inflicted transgressions and sense of betrayal were significantly associated with CUD symptoms (p < .01). In addition, years since release from duty moderated the association between Betrayal and CUD (b=-.039, SE = .018, t=-2.20, p = .028), so that this association was significant only among veterans released approximately two and six years prior to their participation in the study (b = .33, SE = .09, t = 3.71, p < .001; b = .25, t = 3.45, p < .001, respectively), but not among those who were released approximately 10 years ago. A subsequent qualitative study investigated narratives of 14 older veterans, indicating that the process of meaning-making to combat-related experiences is a key in the process of adaptive coping. We conclude that time since release from duty may serve as a protective factor, presumably disentangling the PMIEs-CUD association via the process of meaning making.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methamphetamine Use Practices, Motivations, and Perceived Benefits and Risks: Exploring Differences Between Males and Females.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-14 DOI: 10.1080/02791072.2025.2478090

Madeline Hooten, Sydney Silverstein, Raminta Daniulaityte

{"title":"Methamphetamine Use Practices, Motivations, and Perceived Benefits and Risks: Exploring Differences Between Males and Females.","authors":"Madeline Hooten, Sydney Silverstein, Raminta Daniulaityte","doi":"10.1080/02791072.2025.2478090","DOIUrl":"https://doi.org/10.1080/02791072.2025.2478090","url":null,"abstract":"Methamphetamine use has increased across the US. To develop adequate interventions, understanding differences in male and female methamphetamine use is critical. Conducted in Dayton, Ohio, this study explores sex differences in attitudes and practices of methamphetamine use. Between 12/2019 and 11/2021, the study recruited 91 participants. Bivariate analyses were used to identify sex differences. Of the 91 participants, 52.7% were female, 95.6% were non-Hispanic white, and the mean age was 42.4 (SD 10.6) years. Age of methamphetamine initiation was similar for males and females (31.7 vs. 29.3). Participants reported multiple reasons for methamphetamine use, but females were more likely to report use to quit opioids (60.4% vs. 39.5%, p = .047), lose weight (35.4% vs. 14.0%, p = .019), and self-treat ADHD symptoms (43.8% vs. 16.3%, p = .005). Females were more likely to endorse increased productivity (81.3% vs. 48.8%, p = .001) as a benefit of methamphetamine use. Females were also more likely to endorse the following perceived risks of methamphetamine: depression (91.7% vs. 74.4%, p = .027), skin problems (100.0% vs. 76.2%, p = <0.001), aggression/violence (93.8% vs. 65.1%, p = <0.001), risk of HIV/AIDS (85.4% vs. 60.5%, p = .007), teeth problems (100.0% vs. 90.7%, p = .032), exposure to fentanyl contamination (81.3% vs. 55.8%, p = .009), and increased risk of an overdose (39.6% vs. 16.3%, p = .014).","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Potential of Psilocybin for Treating Neuropsychiatric Long COVID Symptoms: A Reddit Investigation.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-14 DOI: 10.1080/02791072.2025.2478097

Lukas Bobak, Ian Dorney, Alexsandra Kovacevich, Brian S Barnett

{"title":"Therapeutic Potential of Psilocybin for Treating Neuropsychiatric Long COVID Symptoms: A Reddit Investigation.","authors":"Lukas Bobak, Ian Dorney, Alexsandra Kovacevich, Brian S Barnett","doi":"10.1080/02791072.2025.2478097","DOIUrl":"10.1080/02791072.2025.2478097","url":null,"abstract":"Long COVID lacks effective pharmaceutical treatment options. Psychedelic treatment for long COVID has received attention given anecdotal reports of neuropsychiatric symptom improvement. This study investigates the use of psilocybin for neuropsychiatric long COVID symptoms, examining online accounts of individuals with reported long COVID using psilocybin. We searched the Reddit communities, \"r/LongCovid,\" and \"r/covidlonghaulers\" for terms, \"psilocybin,\" \"shrooms,\" and \"magic mushrooms.\" Posts were included if they self-reported (1) neuropsychiatric symptoms of long COVID, (2) use of psilocybin, and (3) descriptions of the perceived effect or lack thereof on long COVID symptoms. Posts were manually coded to identify the nature of psilocybin ingestion, long COVID symptoms, and post's author's perceived effect on symptoms. The most common symptoms identified were fatigue (47.3%, N = 52), cognitive impairment (46.4%, N = 51), and depression (30.0%, N = 33). Of 110 posts meeting criteria, 78.2% (N = 86) reported any improvement in long COVID symptoms, while 11.8% (N = 13) reported worsening. For those with improvement, 77.9% (N = 67) reported improvement lasting beyond their acute psychedelic experience, while 5.8% (N = 5) reported improvement only during the experience. Given these findings, studies employing comparison social media data for other long COVID self-treatments and/or prospective observational studies of individuals self-treating neuropsychiatric long COVID symptoms with psychedelics may be warranted.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meaningful Psychedelic Experiences Predict Increased Moral Expansiveness.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-12 DOI: 10.1080/02791072.2025.2478095

Will Olteanu, Sam G Moreton

引用次数: 0

The Healthcare Profession as a Determinant of Depression, Suicidal Ideation, and Drug Use in Spain During the COVID-19 Pandemic Crisis.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-07 DOI: 10.1080/02791072.2025.2474245

Víctor José Villanueva-Blasco, Adelaida Lozano-Polo, Carlos Guillamó Mínguez, Verónica Villanueva-Silvestre, Manuel Isorna Folgar, Vicente Gea-Caballero, Andrea Vázquez-Martínez

{"title":"The Healthcare Profession as a Determinant of Depression, Suicidal Ideation, and Drug Use in Spain During the COVID-19 Pandemic Crisis.","authors":"Víctor José Villanueva-Blasco, Adelaida Lozano-Polo, Carlos Guillamó Mínguez, Verónica Villanueva-Silvestre, Manuel Isorna Folgar, Vicente Gea-Caballero, Andrea Vázquez-Martínez","doi":"10.1080/02791072.2025.2474245","DOIUrl":"https://doi.org/10.1080/02791072.2025.2474245","url":null,"abstract":"The mental health and substance use of healthcare professionals are vital concerns given their socio-healthcare roles. This study explores whether (a) healthcare profession is associated withthe presence of depression, suicidal ideation, or alcohol, tobacco, and cannabis use, and (b) whether healthcare profession, depression, or suicidal ideation predict substance use. A cross-sectional, observational study was conducted with 630 participants from Psychology, Nursing, Medicine, and Nursing Auxiliary Care Technicians (TCAE). Descriptive analyses and Poisson regression models with robust variance were applied. Results show that TCAE and nurses report higher rates of depression and suicidal ideation, highlighting their vulnerability during health crises. Alcohol is the most consumed substance, with at-risk use prevalent across professions. Tobacco use is highest among psychologists, while cannabis use is low, although 20% of users report problematic use. Severe depression is significantly associated with tobacco use, while its relationships with alcohol and cannabis use are less consistent. Alcohol consumption correlates with sex and healthcare profession, being more common among women, physicians, psychologists, and other healthcare roles. Tobacco use is associated primarily by healthcare profession, while cannabis use is significantly linked to depression, with higher prevalence among professionals without depression. Comprehensive policies addressing these issues are essential.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interactions Between Depressive Symptoms, Childhood Trauma, and Drug Craving in Chinese Men with Methamphetamine Use Disorder: A Network Analysis.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-05 DOI: 10.1080/02791072.2025.2474747

Deyang Li, Dongmei Wang, Yang Tian, Zhaohe Chang, Jiajing Chen, Lianglun Jia, Fabing Fu, Xiaotao Wang, Xiang-Yang Zhang

{"title":"Interactions Between Depressive Symptoms, Childhood Trauma, and Drug Craving in Chinese Men with Methamphetamine Use Disorder: A Network Analysis.","authors":"Deyang Li, Dongmei Wang, Yang Tian, Zhaohe Chang, Jiajing Chen, Lianglun Jia, Fabing Fu, Xiaotao Wang, Xiang-Yang Zhang","doi":"10.1080/02791072.2025.2474747","DOIUrl":"https://doi.org/10.1080/02791072.2025.2474747","url":null,"abstract":"Drug craving in methamphetamine use disorder (MAUD) patients is influenced by various adverse psychological problems. This study adopted network analysis to investigate the interrelationships between psychological correlates and drug craving and identify the critical pathways between them. A total of 757 men with MAUD were recruited from a drug rehabilitation center in southwest China. They completed self-report scales to measure emotion regulation, depressive symptoms, childhood trauma, and drug craving. We conducted a network analysis to assess the interaction between psychological variables and drug craving. Network structural features included network centrality, stability, and bridge strength. Results revealed positive correlations between various psychological correlates and drug craving. Limited access to emotion regulation strategies, lack of emotional awareness, and non-acceptance of emotional responses emerged as the nodes with the highest strength centrality. A bridge function analysis identified that depressive symptoms, emotional abuse, and negative reinforcement were the main bridges connecting psychological problems and drug craving. These findings support the interaction between affective factors, childhood traumatic experiences, and drug craving. Central symptoms (e.g. limited access to emotion regulation strategies) and key bridge symptoms (e.g. depressive symptoms) may serve as potential targets for intervention for MAUD patients undergoing withdrawal treatment.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vermont Primary Care Provider Perspectives on Psychedelics - A Cross-Sectional Study.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-05 DOI: 10.1080/02791072.2025.2474246

Josephine Yalovitser, Jonah Levine, Cole Zweber, Lauren Tien, Mallory Stultz, Henry Mitchell, Elizabeth Cote, Charles D MacLean

{"title":"Vermont Primary Care Provider Perspectives on Psychedelics - A Cross-Sectional Study.","authors":"Josephine Yalovitser, Jonah Levine, Cole Zweber, Lauren Tien, Mallory Stultz, Henry Mitchell, Elizabeth Cote, Charles D MacLean","doi":"10.1080/02791072.2025.2474246","DOIUrl":"10.1080/02791072.2025.2474246","url":null,"abstract":"The medical utility of psychedelics has been the subject of significant scientific interest in recent years. While most of these substances remain Schedule I under the Controlled Substances Act, advancements in research have led states to consider expanding legal access, impacting primary care, where patients often seek mental health support and treatment. In July 2023 we conducted a cross-sectional survey of 770 Vermont primary care providers (PCPs) about their familiarity and concerns with psychedelics, as well as opinions on access and therapeutic value (response rate 17%). Two-thirds of respondents reported familiarity with psychedelics being used therapeutically, but less than half were aware of current regulatory statuses of LSD, psilocybin, and MDMA. Ninety-six percent were neutral or agreed that psychedelics have high therapeutic potential. The highest concerns were effects on youth, potential for psychosis, and traffic safety. Eighty-three percent were not at all or only slightly concerned about the inherent dangers of psychedelics. Seventy-seven percent were interested in further education. Overall, PCPs in Vermont, a state considering changes in access to psilocybin, are familiar with psychedelics, and cautiously optimistic about their therapeutic role. As research develops, it is important to incorporate resultant changes in policy and medicine into PCP continuing education.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Motivations, Experiences, and Consequences of Psychedelic Use in Aotearoa New Zealand.

IF 2.1 4区医学

Journal of psychoactive drugs Pub Date : 2025-03-05 DOI: 10.1080/02791072.2025.2474236

Ethan Mills, Jai Whelan, Sarah McGruddy, Ryan D Ward

{"title":"Exploring Motivations, Experiences, and Consequences of Psychedelic Use in Aotearoa New Zealand.","authors":"Ethan Mills, Jai Whelan, Sarah McGruddy, Ryan D Ward","doi":"10.1080/02791072.2025.2474236","DOIUrl":"https://doi.org/10.1080/02791072.2025.2474236","url":null,"abstract":"While interest in psychedelic research has recently increased globally, little is known about use in Aotearoa New Zealand. Therefore, we sought to explore motivations, features of subjective experience, and impact of use. We also aimed to explore and compare positive, typical, and worst experiences. An online survey was completed by 997 individuals who had used at least one classical psychedelic in Aotearoa New Zealand. Worst, best, and typical experiences were compared, and logistic regression analysis was used to explore predictors of positive psychological health impact. Worst experiences differed substantially from best experiences across emotional, cognitive, and relational domains, while typical experiences more closely resembled best experiences. Motivations for use changed after initial experience, and motivations associated with different experience types varied. A higher number of psychedelic use occasions, as well as therapeutic and growth-oriented motivations, were significant predictors of positive psychological health impact. Consequences of psychedelic use were mostly positive, with best psychedelic experiences resulting in the most benefit. The findings highlight the potential of psychedelic experiences for personal growth and wellbeing and emphasize the need for an open-minded approach to drug education and policy development for the minimization of harm and maximization of benefit regarding psychedelics.","PeriodicalId":16902,"journal":{"name":"Journal of psychoactive drugs","volume":" ","pages":"1-12"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0