Journal of Nutrition最新文献

{"title":"Beans Improve Satiety to an Effect that Is Not Significantly Different from Beef in Older Adults: A Randomized, Crossover Trial","authors":"Megan J Fluit,&nbsp;Brooke F Adams,&nbsp;Zachary J Ribau,&nbsp;Alison M Duncan","doi":"10.1016/j.tjnut.2025.02.008","DOIUrl":"10.1016/j.tjnut.2025.02.008","url":null,"abstract":"<div><h3>Background</h3><div>Beans are a candidate food for increasing satiety due to their protein and dietary fiber content. Beef is a common animal protein that can increase satiety due to its protein content, which is higher than beans but does not contain dietary fiber. Dietary guidance encourages higher intake of plant-based protein foods and warrants satiety studies that compare plant and animal protein foods, which could particularly benefit the rapidly growing population segment of older adults.</div></div><div><h3>Objectives</h3><div>To compare the effects of 2 bean varieties and beef consumed within a breakfast tortilla on satiety, food intake, and 24-h energy intake in older adults.</div></div><div><h3>Methods</h3><div>Older adults [<em>n</em> = 35, age 72.4 ± 6.66 y, BMI (in kg/m²) 25.1 ± 3.25] consumed 3 breakfast tortilla test meals containing 1 serving of black beans (135 g), red kidney beans (135 g), or beef (80 g) in a randomized, crossover design. Participants rated their appetite sensations on periodic visual analogue scales, food intake was measured at an ad libitum pizza lunch meal, and 24-h energy intake was measured using weighed food records. Appetite sensation area under the curves (AUCs) were compared between treatments using repeated-measures analysis of covariance, and food intake and 24-h energy intake were compared using repeated-measures analysis of variance.</div></div><div><h3>Results</h3><div>Fullness and satisfaction were significantly increased, while hunger, desire to eat, and prospective food consumption were significantly decreased, following consumption of the black bean, red kidney bean, and beef test meals. Appetite sensation AUCs, ad libitum pizza intake, and 24-h energy intake did not significantly differ between the test meals.</div></div><div><h3>Conclusions</h3><div>These results demonstrate that beans improve satiety to an extent that is not significantly different from beef in older adults, thereby supporting the role of beans as a nutrient-dense source of protein and dietary fiber as part of a satisfying meal for older adults.</div><div>This trial was registered at <span><span>clinicaltrials.gov</span><svg><path></path></svg></span> as NCT05499819.</div></div>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":"155 4","pages":"Pages 1193-1201"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-Effects of Natural Plant Bioactive Components on Intestinal Health in Pigs: Promising Feed-Antibiotic Alternatives?","authors":"Zhuan Song,&nbsp;Peng Li,&nbsp;Mengjun Wu,&nbsp;Shuangshuang Guo,&nbsp;Tao Wu,&nbsp;Yongqing Hou,&nbsp;Dan Yi","doi":"10.1016/j.tjnut.2025.02.009","DOIUrl":"10.1016/j.tjnut.2025.02.009","url":null,"abstract":"<div><div>The poor intestinal health induced by management, stress, or infection remains a substantial challenge restricting the rapid development of the pig industry. Some natural plant bioactive components (NPBCs) have garnered considerable interest owing to their multifarious benefits, including enhancing intestinal morphology, digestion and absorption, barrier function, immune function, and regulating the gut microbiota. However, there are critical factors, such as the lack of standardized production technologies, lower stability and bioavailability, and unclear mechanisms of NPBCs, severely limiting their feeding efficacy and their application in animal production. Here, we conducted a comprehensive review of the recent advances regarding the impacts of NPBCs on pig gut health. Additionally, we highlighted the key areas that warrant further in-depth investigation. Taken together, NPBCs could be green, safe, and effective feed additives by constructively overcoming their limitations, and they are expected to have broader applications in animal husbandry.</div></div>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":"155 4","pages":"Pages 1068-1076"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"p-Hydroxycinnamic Acids: Advancements in Synthetic Biology, Emerging Regulatory Targets in Gut Microbiota Interactions, and Implications for Animal Health","authors":"Chunlai Ma ,&nbsp;Ziqi Liang ,&nbsp;Yuan Wang ,&nbsp;Huiying Luo ,&nbsp;Xiaojun Yang ,&nbsp;Bin Yao ,&nbsp;Tao Tu","doi":"10.1016/j.tjnut.2025.01.034","DOIUrl":"10.1016/j.tjnut.2025.01.034","url":null,"abstract":"<div><div><em>p</em>-hydroxycinnamic acids (<em>p</em>-HCAs), a class of natural phenolic acid compounds extracted from plant resources and widely distributed, feature a C6-C3 phenylpropanoid structure. Their antioxidant, anti-inflammatory, and antibacterial activities have shown great potential for applications in food and animal feed. The interactions between <em>p</em>-HCAs and the gut microbiota, as well as their subsequent effects on animal health, have increasingly attracted the attention of researchers. In the context of a greener and safer future, the progress and innovation in biosynthetic technology have occupied a central position in ensuring the safety of food and feed. This review emphasizes the complex mechanisms underlying the interactions between <em>p</em>-HCAs and the gut microbiota, providing a solid explanation for the remarkable bioactivities of <em>p</em>-HCAs and their subsequent impact on animal health. Furthermore, it explores the advancements in the synthetic biology of <em>p</em>-HCAs. This review could aid in a basis for better understanding the underlying interactions between <em>p</em>-HCAs and gut microbiota and animal health.</div></div>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":"155 4","pages":"Pages 1041-1056"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Added sugar intake from infant formula and complementary foods: A longitudinal investigation and implications for infant weight gain.","authors":"Jigna M Dharod, Jeffrey D Labban, Helen Tadese, Valerie L Flax, Maureen M Black","doi":"10.1016/j.tjnut.2025.03.025","DOIUrl":"https://doi.org/10.1016/j.tjnut.2025.03.025","url":null,"abstract":"<p><strong>Background: </strong>Infant formula contains added sugar, although national recommendations state that added sugar should be avoided for infants.</p><p><strong>Objectives: </strong>Estimate average daily added sugar intake from formula and complementary foods. Examine associations between added sugar intake from formula and complementary foods and weight status among infants in low-income households.</p><p><strong>Methods: </strong>Between August 2019 and November 2021, mother-infant dyads were recruited from a pediatric clinic primarily serving Medicaid recipients, regardless of feeding type. 24-h feeding recalls were conducted at infant age 6, 9, and 12 months. For directly breast-fed infants, we used the average expected milk volume intake by age. Weight-for-age and weight-for-length z-scores were calculated from health record measurements. Descriptives, bivariate tests, and multilevel linear growth modeling were used.</p><p><strong>Results: </strong>Most participants (n=234) were African American (39%) or Latino (38%). Infants' daily added sugar intake was on average 7 g from complementary foods and 33 g from formula, with formula being the major source at 6 and 9 months. Daily intake of calories due to added sugar was significantly higher among formula-fed infants compared to breastmilk or sugar-free formula-fed infants (p =.034). For every 10 g of added sugar from formula daily, infants' weight-for-length z-scores increased by an average of 0.060 (SE = 0.018, p = .001).</p><p><strong>Conclusions: </strong>Formula significantly contributes to added sugar intake among infants compared to complementary foods. A significant positive association between added sugar from formula and infant weight gain suggests the need for regulations limiting added sugar in formula and including added sugar information on formula food labels.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cafeteria Diet-Induced Obesity Alters Uterine Function by Disrupting Insulin and Sex Steroid Actions in Rats.","authors":"Divya Srinivasan, Harini Raghavendhira, Mohammad Zafar Iqbal Khan, Saranya Kannan, Ravisankar Bhaskaran","doi":"10.1016/j.tjnut.2025.03.029","DOIUrl":"https://doi.org/10.1016/j.tjnut.2025.03.029","url":null,"abstract":"<p><strong>Background: </strong>The cafeteria diet (CAFD) model leads to obesity in rats, disrupting glucose metabolism, hormonal balance and ovarian function, which results in macrosomic offspring. Insulin and ovarian hormones are essential for uterine growth, but there is limited research on how CAFD-induced obesity affects uterine function by modulating hormonal levels.</p><p><strong>Objective: </strong>This study assesses how CAFD-induced obesity impacts uterine function in adult female rats by analysing ovarian steroids, insulin levels, and uterine responses.</p><p><strong>Materials & methods: </strong>Post-weaning female Sprague-Dawley rats (22 days), were divided into a control group fed standard chow and an obese group fed energy-dense snacks (CAFD) and standard chow for 32 weeks. Body weight, food intake, energy intake, and estrous cycles were monitored during the experiment. After the experimental period, the uterine tissues were evaluated histologically, and protein expression was analysed using Western blotting and immunofluorescence. Serum hormone levels were assessed by ELISA, and uterine oxidative stress markers (SOD, CAT, GSH, LPO, and vitamin C) were measured using spectrophotometric methods.</p><p><strong>Results: </strong>CAFD-fed rats exhibited increased body weight, BMI, and abdominal girth, along with hyperglycaemia, extended estrous cycles averaging 8.9 days and 40% reduction in uterine weight (p<0.05). The expression of PCNA was elevated (p<0.001), with a significant increase in uterine cell proliferation. Obese rats showed lower levels of SOD, GSH, and vitamin C, while levels of LPO and CAT were higher in uteri (p<0.05). Exposure to CAFD significantly reduced serum levels of prolactin, progesterone, and estradiol. Moreover, progesterone receptor and its target molecules (IHH, PPARγ, PRLR) were upregulated, while estrogen receptor-α (p<0.001) and its responsive molecules (VEGF, HOXA11) were downregulated (p<0.05).</p><p><strong>Conclusion: </strong>Consumption of CAFD caused obesity, leading to hyposecretion of ovarian steroids, insulin and oxidative stress in the uterus, which affected the uterine milieu by altering the expression of key molecules involved in uterine function.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum 25-hydroxyvitamin D and intact parathyroid hormone as functional biomarkers of bone mass in early childhood.","authors":"Karen M O'Callaghan, Celine Funk, Farzana Fariha, Marium H Nagaria, Alison Dasiewicz, Jennifer Harrington, Abdullah Al Mahmud, Steven A Abrams, Tahmeed Ahmed, Daniel R Moore, Daniel E Roth","doi":"10.1016/j.tjnut.2025.03.022","DOIUrl":"https://doi.org/10.1016/j.tjnut.2025.03.022","url":null,"abstract":"<p><strong>Background: </strong>The 25-hydroxyvitamin D concentration (25(OH)D) at which parathyroid hormone (PTH) concentration plateaus has been considered to benchmark vitamin D deficiency. However, in young children, there is limited evidence for a suppression point in the 25(OH)D-PTH relationship or its relevance to bone mass accrual.</p><p><strong>Objective: </strong>To determine whether the threshold of 25(OH)D at PTH suppression in young children is corroborated by associations of 25(OH)D (or PTH) with bone mineral content (BMC) and areal bone mineral density (aBMD).</p><p><strong>Methods: </strong>In a cross-sectional secondary analysis of data from the BONe and mUScle health in Kids (BONUSKids) study of 4-year old children in Bangladesh, serum 25(OH)D and intact PTH (iPTH) were analyzed by liquid chromatography-tandem mass spectrometry and a chemiluminescent immunoassay, respectively. BMC and aBMD were measured by dual-energy X-ray absorptiometry. Associations between 25(OH)D, iPTH and bone outcomes (BMC, BMC z-score, aBMD and aBMD z-score) were modelled using multivariable-adjusted linear regression and spline models. Model fit was compared using AIC.</p><p><strong>Results: </strong>Of 534 participants (51% female), 28% had 25(OH)D concentrations <25nmol/L and 34% had iPTH >6.7pmol/L. Model fit of the inverse relationship between 25(OH)D and iPTH was optimised with an inflection point at 25nmol/L (<25nmol/L: -0.16pmol/L per 1nmol/L increase in 25(OH)D; 95%CI: -0.22, -0.10; P<0.001), above which the slope attenuated (≥25nmol/L: -0.02pmol/L; 95%CI: -0.04, -0.003; P=0.019). However, the positive linear associations between 25(OH)D and bone mass outcomes were monotonic (P<0.05), and iPTH was not associated with any bone outcome in adjusted models (P>0.05 for all). Associations were similar in males and females.</p><p><strong>Conclusions: </strong>Among 4-year old children in Dhaka, Bangladesh, we did not identify a 25(OH)D threshold to define vitamin D deficiency based on its association with bone mass. However, efforts to raise 25(OH)D to ≥25nmol/L may be warranted based on the relatively strong inverse association of 25(OH)D with iPTH below this threshold.</p><p><strong>Clinical trial registry: </strong>Clinicaltrials.gov #NCT03537443.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Corn Flour Consumption on Human Health Across the Lifespan: A Scoping Review.","authors":"Alex E Mohr, Corrie M Whisner","doi":"10.1016/j.tjnut.2025.03.028","DOIUrl":"https://doi.org/10.1016/j.tjnut.2025.03.028","url":null,"abstract":"<p><p>Corn flour, a staple food in many regions worldwide, plays a significant role in the diet due to its versatility and broad food applications. Currently, there is no comprehensive synthesis of peer-reviewed research related to human corn flour consumption and health outcomes. This scoping review aimed to examine the current literature on the health effects of corn flour across diverse populations. Three databases (PubMed, Scopus, and CINAHL) were systematically searched in July 2024 for articles that reported on human corn flour consumption and health outcomes. Eligible studies were written in English, peer-reviewed, and compared corn flour to a grain-based or no intervention comparator. Twenty-one studies were included, investigating a wide range of health outcomes, including metabolic markers, growth metrics in infants, and the risk of chronic diseases such as type 2 diabetes, obesity, and hypercholesterolemia. Findings indicated that whole grain corn products, particularly those high in fiber-rich corn bran, were associated with favorable effects on blood lipid and glycemic profiles. Conversely, refined corn products, such as cornflakes and extruded snacks, were linked to less favorable metabolic outcomes, particularly in individuals with metabolic disorders. This review highlights the potential of corn flour to affect health depending on its processing and consumption context. While fiber-rich forms of corn flour may offer metabolic benefits, highly processed varieties may exacerbate metabolic risks. There is a clear need for more rigorous, larger-scale studies to better understand the long-term health impacts of corn flour consumption and its role in health. REGISTRY NUMBER: Open Science Framework; https://doi.org/10.17605/OSF.IO/9B8KR.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Umbrella Review of Systematic Reviews and Meta-Analyses on Consumption of Different Food Groups and Risk of Type 2 Diabetes Mellitus and Metabolic Syndrome.","authors":"Rivana Lambani Banjarnahor, Elaheh Javadi Arjmand, Anindita Tasnim Onni, Lise M Thomassen, Matteo Perillo, Rajiv Balakrishna, Ida Sofie Karlsen Sletten, Antonello Lorenzini, Pierluigi Plastina, Lars T Fadnes","doi":"10.1016/j.tjnut.2025.03.021","DOIUrl":"10.1016/j.tjnut.2025.03.021","url":null,"abstract":"<p><p>Type 2 diabetes is a major contributor to the burden of chronic diseases globally. Most cases of type 2 diabetes are preventable through healthy lifestyle modifications in diet and physical activity. This systematic umbrella review presents a comprehensive overview of the evidence about the associations between risk of type 2 diabetes and metabolic syndrome with 13 food groups, including refined and whole grains, fruits, vegetables, nuts, legumes, fish and fish products, eggs, dairy/milk, sugar-sweetened beverages, processed meat, and unprocessed red and white meat. We present these relationships in per-serving and with high-versus-low comparisons. After doing a systematic search in MEDLINE, Embase, Web of Science, and Epistemonikos (registered with PROSPERO: CRD42024547606), we screened 5074 references published until May 15, 2024, and included 67 articles. This included 46 meta-analyses on risk of type 2 diabetes with half a million participants, 17 meta-analyses on risk of metabolic syndrome, and 4 meta-analyses on risk of diabetes-related mortality. Based on quality assessments using AMSTAR-2, 25 of the 67 studies were classified as high-quality studies, 8 as moderate, 12 as low, and 22 as critically low quality. Our results showed that a high intake of whole grains was associated with a lower risk of type 2 diabetes (metaevidence: moderate) and metabolic syndrome (metaevidence: low), with a similar tendency also for a high intake of fruits and vegetables (metaevidence: moderate). In contrast, the high intakes of processed meat (metaevidence: high), red meat (metaevidence: moderate), and sugar-sweetened beverages (metaevidence: moderate) were associated with a higher risk of type 2 diabetes. For the other food groups, the associations were generally neutral and not statistically significant. The heterogeneity was high for most food groups except fruits, indicating potential differences within each of the food groups in association with type 2 diabetes.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary amino acids and risk of stroke subtypes: Results from three large prospective cohort studies.","authors":"Tammy Y N Tong, Yanping Li, Kathryn M Rexrode, Walter C Willett, Qi Sun, JoAnn E Manson, Valter D Longo, Timothy J Key, Frank B Hu","doi":"10.1016/j.tjnut.2025.03.026","DOIUrl":"10.1016/j.tjnut.2025.03.026","url":null,"abstract":"<p><strong>Background: </strong>Differences in dietary protein have been associated with stroke risk, with possible heterogeneity in associations by stroke type or food sources of protein.</p><p><strong>Objective: </strong>We examined the associations of individual dietary amino acids, as the constituents of dietary protein, with risks of ischemic, hemorrhagic and total stroke.</p><p><strong>Methods: </strong>We analysed data from 73,830 women in the Nurses' Health Study (1984-2012), 92,333 women in the Nurses' Health Study II (1991-2013), and 43,268 men in the Health Professionals Follow-Up Study (1986-2016). Dietary intakes of 22 (20 standard and two non-standard) amino acids were assessed using validated food frequency questionnaires, administered typically every four years. Multivariable-adjusted Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of ischemic, hemorrhagic and total stroke in relation to the energy-adjusted intakes of individual amino acids.</p><p><strong>Results: </strong>During an average follow-up of 23.7 years, 3058 ischemic, 872 hemorrhagic and 5997 total stroke cases were documented. After correction for multiple testing, lower risks of ischemic stroke were observed with higher intakes of glutamine (HR per 1 SD higher: 0.94, 95% CI: 0.90-0.98, p-value=0.004) and proline (0.94, 0.90-0.98, p-value=0.005). The associations remained directionally consistent across sensitivity analyses, but attenuated upon mutual adjustment. All other amino acids, including branched-chain amino acids, were not significantly associated with ischemic stroke. For hemorrhagic stroke, no significant associations were observed for any of the amino acids. For total stroke, inverse associations were also observed for both glutamine (0.94, 0.91-0.97, p-value<0.001) and proline (0.96, 0.93-0.99, p-value=0.004). In terms of dietary sources, glutamine was most strongly correlated with plant protein and whole grains, while proline was most strongly correlated with dairy protein and dairy products.</p><p><strong>Conclusions: </strong>Higher intakes of glutamine and proline were associated with lower risks of ischemic and total stroke.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotics and Prebiotics: Meeting Dietary Requirements for Optimal Health and Planetary Sustainability.","authors":"Juan Chen, Yifei Yu, SiYuan Sun, Weiru Yu, Yumei Lei, Chenxu Lu, Jianan Zhai, Feirong Bai, Fazheng Ren, Ran Wang","doi":"10.1016/j.tjnut.2025.03.027","DOIUrl":"10.1016/j.tjnut.2025.03.027","url":null,"abstract":"<p><p>Probiotics and prebiotics are valuable in enhancing human health and fostering sustainable development. This review focuses on the role of probiotics and prebiotics at all stages of life to promote nutrient absorption, boost immunity, and support healthy aging by mitigating cognitive decline and chronic disease. Health and environmental sustainability are deeply connected, making probiotics and prebiotics promising tools for promoting well-being and achieving global sustainability goals. In addition to health, probiotics and prebiotics contribute to sustainable development by optimizing agricultural byproducts, reducing reliance on antibiotics in animal feed, lowering greenhouse gas emissions, and supporting environmental protection. Future research should focus on personalizing treatments, improving bioavailability, and expanding applications to effectively address global health and the sustainable development goals.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}