Journal of oral biology and craniofacial research最新文献

{"title":"To evaluate the effect of oral zinc supplementation on salivary MMP-8 levels in periodontitis: A randomized, double-blind, placebo-controlled study","authors":"Vishakha Gupta ,&nbsp;Pavitra Rastogi ,&nbsp;Sadhna Ajay ,&nbsp;Nand Lal ,&nbsp;Umesh Pratap Verma ,&nbsp;Rameshwari Singhal ,&nbsp;Anjani Kumar Pathak ,&nbsp;Nitu Nigam ,&nbsp;Paridhi Rastogi","doi":"10.1016/j.jobcr.2025.02.013","DOIUrl":"10.1016/j.jobcr.2025.02.013","url":null,"abstract":"<div><h3>Background and objective</h3><div>Zinc is an essential micronutrient that plays a crucial role in maintaining oral health. Periodontitis is a widespread oral disease characterized by inflammation and destruction of the gums and surrounding tissues. The objective of this study was to evaluate the effect of oral zinc supplementation as an adjunct to scaling and root planing in the treatment of periodontitis by evaluating its effects on clinical parameters and salivary MMP-8 level.</div></div><div><h3>Methods</h3><div>42 patients were enrolled in the study from the periodontology OPD of a tertiary care hospital in India. The subjects were divided into two groups: group 1 and group 2 consisting of 21 patients each of moderate to severe periodontitis. Group 1 was given oral zinc supplementation along with scaling and root planing (SRP) and group 2 was given placebo tablet along with SRP for 1 month. Several periodontal parameters were assessed, including Papillary bleeding Index (BI), Gingival index (GI), Probing pocket depth (PPD) and Clinical attachment level (CAL) at baseline as well as at 1 month post treatment. Around 3 ml of whole unstimulated saliva was collected for MMP-8 estimation by ELISA method at baseline as well as at 1 month.</div></div><div><h3>Results</h3><div>The data was analyzed using SPSS version 26. All clinical parameters and MMP-8 level in saliva were comparable at baseline. 1 month after respective treatment modalities were performed in each group, it was found that all clinical parameters and salivary MMP-8 level showed significant differences with group 1 (zinc + SRP) showing highly significant decrease in GI, PPD and CAL (p &lt; 0.01) and significant decrease in BI and salivary MMP-8 level when compared to group 2 (placebo + SRP) (p &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>When compared with scaling and root planing alone, the administration of oral zinc supplementation along with scaling and root planing showed greater reduction in clinical parameters and salivary MMP-8 levels in patients with moderate to severe periodontitis. Zinc has a positive effect in management of periodontitis and can serve as an easy, cost effective, harmless and beneficial adjunct in treatment of periodontitis.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 493-499"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taste perception and muscular response: EMG based experimental evaluation","authors":"Bhavya Rohatgi ,&nbsp;Ramya Ramadoss ,&nbsp;K. Nitya ,&nbsp;Sandhya Sundar ,&nbsp;Suganya Panneer Selvam ,&nbsp;K. Hema Shree","doi":"10.1016/j.jobcr.2025.02.016","DOIUrl":"10.1016/j.jobcr.2025.02.016","url":null,"abstract":"<div><h3>Background</h3><div>Taste perception influences not only flavor preference but also the physiological processes of chewing and digestion. Each primary taste—sweet, sour, salty, bitter, and umami—affects specific receptors and shapes masticatory muscle activity, notably in the temporalis and masseter muscles. Limited research exists on how taste affects muscle synergy (coordinated activation) and symmetry (balanced activation) in chewing. Using surface electromyography (EMG), this study examines how different tastes impact these muscle dynamics, offering insights relevant to dentistry, nutrition, and food science.</div></div><div><h3>Methods</h3><div>This study included five healthy participants aged 18–22 years. EMG recordings were conducted on the temporalis anterior and masseter muscles. Each participant chewed five distinct jelly formulations (sweet, sour, salty, bitter, umami) prepared with standardized flavours. The muscle activity was analyzed to determine the effects of taste on muscle synergy (right and left temporalis and masseter) and symmetry (temporalis and masseter). Paired t-tests and ANOVA were used to assess statistical significance.</div></div><div><h3>Results</h3><div>The results revealed taste-dependent variations in muscle synergy and symmetry. Sweet and salty tastes increased muscle synergy, while bitter and umami decreased it. Minimal changes were observed in the symmetry of the temporalis muscle across taste conditions, while the symmetry of the anterior masseter showed notable variations, especially with salty and umami. However, statistical analysis indicated no significant differences in muscle synergy or symmetry between jelly and non-jelly conditions across all taste stimuli (p &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>This study underscores the complexity of the neuromuscular response to taste perception, suggesting potential subtle influences of taste on muscle activity. Future research with a larger sample size and advanced statistical methods may further elucidate the role of taste in modulating masticatory muscle function.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 472-477"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidants for the management of oral leukoplakia: A systematic review of randomized controlled trials","authors":"Divya Gopinath ,&nbsp;Sara Ibrahim Waki ,&nbsp;Kwok Fu Cheah ,&nbsp;Swagatika Panda","doi":"10.1016/j.jobcr.2025.03.001","DOIUrl":"10.1016/j.jobcr.2025.03.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Oral leukoplakia (OL) is a potentially malignant disorder characterized by non-scrabble white lesions that may turn into invasive carcinoma if left untreated. Few antioxidant treatments have shown promising results in the regression of lesions and prevention of their progression to carcinoma. We aim to summarize the current evidence on the effectiveness of antioxidants in the management of OL.</div></div><div><h3>Materials and methods</h3><div>The present systematic review followed PRISMA guidelines and involved a thorough search of three scientific databases: PubMed, Scopus, and Cochrane. We used specific algorithms related to the keywords “antioxidant” and “Oral leukoplakia” to identify randomized controlled trials (RCTs) that have explored the utility of antioxidants in the management of OL. The risk of bias assessment was conducted using the Cochrane risk of bias tool (ROB 2.0), ensuring the reliability of our findings.</div></div><div><h3>Results</h3><div>Out of 2490 articles retrieved, only thirteen RCTs involving 1147 participants fulfilled the inclusion criteria. Lycopene was found to be the most consistently effective antioxidant, showing significant effectiveness in reducing lesion size, both in oral and topical forms. The trials incorporating other antioxidants, including vitamin A, vitamin C, β-carotene, and curcumin, demonstrated mixed results. Severe heterogeneity was detected in treatment forms, dosage, administration frequency, treatment duration, and follow-up time among all included trials.</div></div><div><h3>Conclusion</h3><div>Lycopene may play a significant role in the non-surgical management of OL. Future research with large-scale, well-designed, randomized controlled trials with standardized dosing, delivery methods, and outcome measures is mandatory to provide more robust evidence on the available antioxidant therapy for OL.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 484-492"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative assessment of pericervical dentin in mandibular second primary molars through stress distribution analysis: A finite element study","authors":"Selvakumar Haridoss ,&nbsp;Mathan Rajan R ,&nbsp;Anbarasi K ,&nbsp;Vijayaragavan E ,&nbsp;Kavitha Swaminathan","doi":"10.1016/j.jobcr.2025.02.011","DOIUrl":"10.1016/j.jobcr.2025.02.011","url":null,"abstract":"<div><h3>Objective</h3><div>The purpose of this study was to quantify the Pericervical Dentin (PCD) in the mandibular second primary molar and its role in maintaining structural integrity under masticatory loads using Finite Element Analysis (FEA). By identifying the distribution and stress-bearing capacity of PCD, we aim to recommend treatment protocols that maintain PCD to improve fracture resistance in pediatric endodontics.</div></div><div><h3>Methods</h3><div>A 3D model of a mandibular second primary molar was generated from Cone Beam Computed Tomography (CBCT) scans and analyzed using FEA software. Simulated masticatory loads of 353.64 N (maximum), 169.3 N (mean), and 8.05 N (minimum) were applied at angles of 0°, 45°, and 90° to represent vertical, lateral, and maximum masticatory forces. PCD was quantified by measuring stress distribution along buccal, lingual, mesial, and distal surfaces.</div></div><div><h3>Results</h3><div>The analysis revealed that the stress-bearing region in the mandibular second primary molar extends approximately 1–1.5 mm from the Cemento-enamel Junction (CEJ) towards the coronal aspect and 1–1.5 mm from the CEJ towards the radicular aspect, creating a critical 3 mm zone of PCD. The highest stress was consistently found within this PCD zone across on all surfaces of the tooth, highlighting its importance for the tooth’s structural stability.</div></div><div><h3>Conclusion</h3><div>A quantitative analysis of the 3 mm PCD zone (coronal and radicular aspect from the CEJ) emphasizes its critical role in strengthening teeth. Based on these findings, we recommend conservative cavity preparation in pediatric endodontics on preserving PCD to avoid structural weakening and improve long-term clinical outcomes.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 478-483"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chitosan from sea urchin (Diadema setosum) spines for orthodontic miniscrews: Antibacterial effects against key oral pathogens","authors":"Karima Qurnia Mansjur ,&nbsp;Eka Erwansyah ,&nbsp;Ardiansyah S Pawinru ,&nbsp;Mansjur Nasir ,&nbsp;Arni Irawaty Djais ,&nbsp;Virgino Calvine Sumule ,&nbsp;Nurnabilla Syfadewi Attaya ,&nbsp;Dian Yosi Arinawaty ,&nbsp;Islamy Rahma Hutami ,&nbsp;Andi Dian Permana","doi":"10.1016/j.jobcr.2025.02.014","DOIUrl":"10.1016/j.jobcr.2025.02.014","url":null,"abstract":"<div><h3>Objective</h3><div>Peri-implantitis, exacerbated microbial growth characterized by progressive bone loss and soft-tissue inflammation, significantly contributes to miniscrew failure during orthodontic treatment. Using a natural antibacterial coating presents an innovative approach to combat bacterial colonization. Sea urchin (<em>Diadema setosum</em>) spines containing chitosan (CS) exhibit notable antibacterial properties and biocompatibility effects. This study investigates the antimicrobial potential of CS from sea urchin spines applied onto the surfaces of orthodontic miniscrews, aiming to mitigate the impact of peri-implantitis.</div></div><div><h3>Materials and methods</h3><div>The surface functional groups, phase composition, and crystal structure of CS were investigated using traditional examination methods alongside energy-dispersive X-ray analysis. The antibacterial activity of CS was evaluated against three bacteria by the disk diffusion method, minimum bacterial concentration (MBC), and minimum inhibitory concentration (MIC). Stainless steel miniscrews were coated with CS, and the surface was characterized by scanning electron microscopy (SEM).</div></div><div><h3>Results and discussion</h3><div>Sea urchin-derived chitosan demonstrated significant antibacterial effects against key oral pathogens associated with peri-implantitis, with minimum inhibitory concentrations (MICs) of 16 ppm against <em>Fusobacterium nucleatum</em> and 32 ppm for both <em>Aggregatibacter actinomycetemcomitans</em> and <em>Porphyromonas gingivalis</em>. The minimum bactericidal concentrations (MBCs) were 4 ppm for <em>A. actinomycetemcomitans</em> and 16 ppm for both <em>F. nucleatum</em> and <em>P. gingivalis,</em> indicating its strong bactericidal potential. Scanning electron microscopy (SEM) revealed that sea urchin chitosan effectively adhered to the surface of orthodontic miniscrews, showcasing its potential as a functional antimicrobial coating. These results emphasize the capability of sea urchin chitosan to target key oral pathogens, offering a promising approach to enhance microbial resistance and improve outcomes in orthodontic treatments.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 463-471"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supernumerary teeth: A pictorial review and revised classification","authors":"Christy Lana Davidson ,&nbsp;Chané Smit ,&nbsp;Sulette Nel","doi":"10.1016/j.jobcr.2025.03.005","DOIUrl":"10.1016/j.jobcr.2025.03.005","url":null,"abstract":"<div><div>Current literature regarding supernumerary teeth poses the risk of confusion as ambiguity in the terminology and classification of supernumerary teeth permits differing interpretations.</div><div>Uncertainty in this regard distorts data on the true incidence and prevalence of supernumerary teeth. This pictorial review provides an overview of the current understanding regarding the development of supernumerary teeth, their positional and morphological classification, and eruptive alterations. We highlight the ambiguity in defining supernumerary teeth and propose an updated classification for the description of these teeth.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 454-462"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced hierarchical attention networks for predictive interactome analysis of LncRNA and CircRNA in oral herpes virus","authors":"Pradeep Kumar Yadalam ,&nbsp;Carlos M. Ardila","doi":"10.1016/j.jobcr.2025.02.012","DOIUrl":"10.1016/j.jobcr.2025.02.012","url":null,"abstract":"<div><h3>Background</h3><div>Non-coding RNAs, including lncRNAs, circRNAs, and microRNAs, constitute 98 % of the human transcriptome and are vital regulators of gene expression, cellular processes, and host-pathogen interactions, particularly in viral infections. This study explores lncRNA-circRNA interactions and their biological significance in oral viral infections.</div></div><div><h3>Methods</h3><div>ViRBase, a database with over 820,000 interactions involving 50,000 RNAs from 116 viruses and 36 host organisms, was used to analyze herpesvirus datasets. The study employed hierarchical attention and knowledge graph embeddings to represent nodes and edges in the knowledge graph. These served as input features for a hierarchical attention model trained over 100 epochs. Model performance was evaluated based on loss calculation, optimization, and attention weight stability.</div></div><div><h3>Results</h3><div>The model achieved a final loss of 0.000180 at Epoch 100, with stable attention weights confirming reliability. Node embedding statistics showed a mean of 0.005110 and a standard deviation of 0.013370, while attention weights had a high mean of 0.997178, emphasizing model robustness.</div></div><div><h3>Conclusion</h3><div>This study provides insights into lncRNA-circRNA interactions in herpes viral infections, enhancing therapeutic development, disease progression monitoring, and understanding host-pathogen interactions, paving the way for targeted interventions and improved outcomes.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 445-453"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of MSX1 gene polymorphisms and maxillary lateral incisor agenesis in Non-syndromic cleft lip and/or palate individuals","authors":"Dhanyashri Kamalakannan ,&nbsp;Vignesh Kailasam ,&nbsp;Sridevi Padmanaban ,&nbsp;Solomon F.D. Paul ,&nbsp;Gnanasambandan Ramanathan","doi":"10.1016/j.jobcr.2025.02.003","DOIUrl":"10.1016/j.jobcr.2025.02.003","url":null,"abstract":"<div><h3>Background</h3><div>To investigate the association between MSX1 gene polymorphisms and maxillary lateral incisor agenesis with and without Non Syndromic Cleft lip and palate (NSCL/P) in a South Indian population.</div></div><div><h3>Methods</h3><div>The study sample was divided into four groups: Group I: Twenty five Cleft lip and palate (NSCL/P) subjects with unilateral/bilateral congenitally missing maxillary lateral incisors, without agenesis of any other permanent teeth, Group II: Twenty five individuals with NSCL/P and a full complement of teeth, Group III: Twenty five non-cleft individuals with unilateral/bilateral congenitally missing maxillary lateral incisors and Control group: Twenty five healthy individuals with normal teeth development and without orofacial defects. MSX1 gene polymorphisms rs12532, rs1042484 and rs11726039 were genotyped by Sanger sequencing method with pre designed primer using ABI 3730 DNA sequencer. Associations were tested using Pearson Chi-square analysis.</div></div><div><h3>Results</h3><div>The three SNPs, rs12532, rs1042484 and rs11726039 of MSX1 gene exhibited polymorphism. rs12532 was associated with reduced risk of maxillary lateral incisor agenesis in NSCL/P subjects. rs1042484 had significant association with the NSCL/P without maxillary lateral incisor agenesis (full complement of teeth) subjects. rs11726039 showed significant association with NSCL/P with or without maxillary lateral incisor agenesis.</div></div><div><h3>Conclusion</h3><div>The present study on a South Indian population revealed a significant association between the MSX1 gene polymorphisms and tooth agenesis in NSCL/P subjects. Keywords: MSX1, non syndromic cleft lip and palate, lateral incisor agenesis.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 440-443"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of Willems and Cameriere methods of dental age estimation among 6–14 year old Bengali children","authors":"Mehuli Kar ,&nbsp;Aruna Sharma ,&nbsp;Kaushik Dutta ,&nbsp;Rekha Puttanavar ,&nbsp;Sanguida A ,&nbsp;Ezhumalai Govindasamy","doi":"10.1016/j.jobcr.2025.02.006","DOIUrl":"10.1016/j.jobcr.2025.02.006","url":null,"abstract":"<div><h3>Background</h3><div>The knowledge of dental age estimation is essential to assess growth and development which aids in designing a treatment plan. Willems and Cameriere methods are the two most widely used approaches of dental age estimation.</div></div><div><h3>Aim</h3><div>The primary objective of this study was to evaluate the reliability and applicability of the two methods, among 6–14 year old children of Bengal populace. The secondary objective was to compare the efficacy of Sante DICOM Viewer and CorelDRAW Graphic Suite in assessing dental age by Cameriere method.</div></div><div><h3>Materials and methods</h3><div>The study sample encompassed 411 digital panoramic radiographs. Dental age was estimated using Willems and Cameriere methods. CorelDRAW Graphic Suite and Sante DICOM Viewer software were used for dental age estimation by Cameriere method. Paired <em>t</em>-test was applied for the inter group comparison. Pearson correlation coefficient was also used to measure the regression among all the groups.</div></div><div><h3>Results</h3><div>Dental age was overestimated by 0.286 years using Willems method (p = 0.001). However, there was no significant difference between dental ages estimated by Cameriere method using both software (p = 0.130).</div></div><div><h3>Conclusion</h3><div>Both the methods were equally applicable for age estimation in the targeted population. Cameriere method can be performed with equivalent accuracy using both software.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 433-439"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of nutritional status on dental maturation and mandibular bone density among Indonesian children aged 6–9 Years in Yogyakarta","authors":"Abshari Rizky Sudjatmoko ,&nbsp;Supartinah Santoso ,&nbsp;Ryna Dwi Yanuaryska","doi":"10.1016/j.jobcr.2025.02.010","DOIUrl":"10.1016/j.jobcr.2025.02.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Growth and development in children depend significantly on their nutritional status; therefore, nutritional deficiencies can greatly influence dental and bone maturity. The level of dental maturation can be used to measure dental development. Mandibular bone density (MBD) can directly impact certain invasive procedures, such as extractions and dental trauma management. This study aimed to determine the influence of nutritional status on dental maturation and MBD in children aged 6–9 years.</div></div><div><h3>Materials and methods</h3><div>The study used 108 panoramic radiographs from children in this age and divided them into three groups: low, moderate, and high nutritional status. The nutritional status was determined on the basis of height-for-age (H/A) z-scores using the WHO H/A chart. The dental maturity score was calculated as the total score of the seven mandibular teeth in the left region using the Nolla method. Using fractal analysis, MBD was measured as the average fractal dimension values from three regions of interest (ROI): the condyle, angle, and below the second premolar and first permanent molar of the left mandible. Data were analyzed using one-way ANOVA for dental maturation levels and the Kruskal-Wallis test for MBD (95 % CI).</div></div><div><h3>Results</h3><div>The results showed significant differences in dental maturation levels between the nutritional status groups, with dental maturation in the low-nutrition group being significantly slower than in the other groups. The MBD showed no significant differences between the nutritional status groups.</div></div><div><h3>Conclusion</h3><div>This study concluded that nutritional status influences the level of dental maturation, but not MBD.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 428-432"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}