Journal of oral biology and craniofacial research最新文献

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Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study 1%玫瑰花纳米乳剂提取物(芙蓉)对正畸微型种植体种植周相关细菌的抑菌活性:体外研究
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.017
Ridhofar Akbar Khusnul Abdillah , Theresia Indah Budhy , Ida Bagus Narmada , I Gusti Aju Wahju Ardani , Nastiti Faradilla Ramadhani , Ratri Maya Sitalaksmi , Muhammad Luthfi , Ninik Mas Ulfa , Albertus Putera Nugraha , Tengku Natasha Eleena binti Tengku Ahmad Noor , Alexander Patera Nugraha
{"title":"Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study","authors":"Ridhofar Akbar Khusnul Abdillah ,&nbsp;Theresia Indah Budhy ,&nbsp;Ida Bagus Narmada ,&nbsp;I Gusti Aju Wahju Ardani ,&nbsp;Nastiti Faradilla Ramadhani ,&nbsp;Ratri Maya Sitalaksmi ,&nbsp;Muhammad Luthfi ,&nbsp;Ninik Mas Ulfa ,&nbsp;Albertus Putera Nugraha ,&nbsp;Tengku Natasha Eleena binti Tengku Ahmad Noor ,&nbsp;Alexander Patera Nugraha","doi":"10.1016/j.jobcr.2024.12.017","DOIUrl":"10.1016/j.jobcr.2024.12.017","url":null,"abstract":"<div><h3>Objective</h3><div>The orthodontic mini-implant (OMI) failure often occurs due to the accumulation of peri-implantitis bacteria surrounding it, which results in a stable, resistant form of absolute skeletal anchorage during orthodontic treatment. Administering doxycycline may be the solution, but long-term side effects result in antibiotic resistance. Roselle flowers (Hibiscus sabdariffa) possess beneficial active phytochemical substances, which may have potential as an OMI peri-implantitis alternative therapy. This study investigates the antibacterial activity of 1 % Roselle flower (H. sabdarifa) nanoemulsion (NE) extract (1 % RNE) toward peri-implantitis bacteria in OMIs.</div></div><div><h3>Methods</h3><div>A phytochemical analysis of 1 % RNE was carried out to examine the active substances possessed in it, such as flavonoids, quinone, saponin, alkaloids, tannins, terpenoids, and steroids. Nanoemulsion characterization was carried out using a particle size analyzer (PSA). The antibacterial activity of 1 % RNE toward Prevotella intermedia (Pi), Porphyromonas gingivalis (Pg), Aggregatibacter actinomycetemcomitans (Aa), and Fusobacterium nucleatum (Fn) was carried out to determine the minimum inhibitory concentration, minimum bactericidal concentration, and inhibitory zone compared with doxycycline as a positive control.</div></div><div><h3>Results</h3><div>Roselle flower NE extract (1 %) possessed flavonoids, quinone, saponin, alkaloids, tannins, terpenoids, and steroids positively. The PSA showed that the 1 % RNE had a size of 98.13 d nm. The antibacterial activity of 1 % RNE against Aa, Pg, Pi, and Fn bacteria at 3.125 % showed significant differences (p &lt; 0.05). The antibacterial activity of 1 % RNE toward peri-implantitis bacteria is lower than that of doxycycline.</div></div><div><h3>Conclusion</h3><div>Roselle flower NE extract (1 %) has antibacterial activity against peri-implantitis bacteria at a concentration of 3.125 %.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 170-177"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Third molar infections and their impact on systemic health- an awareness study among women degree college students of Udupi City, Karnataka, India 第三磨牙感染及其对全身健康的影响——印度卡纳塔克邦Udupi市女大学生意识研究
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2025.01.002
Ananya Prabhu , Ramprasad Vasthare , Prajna P. Nayak , Gargi Gandhi , Shreyosi Banik , Bidisha Sarmah
{"title":"Third molar infections and their impact on systemic health- an awareness study among women degree college students of Udupi City, Karnataka, India","authors":"Ananya Prabhu ,&nbsp;Ramprasad Vasthare ,&nbsp;Prajna P. Nayak ,&nbsp;Gargi Gandhi ,&nbsp;Shreyosi Banik ,&nbsp;Bidisha Sarmah","doi":"10.1016/j.jobcr.2025.01.002","DOIUrl":"10.1016/j.jobcr.2025.01.002","url":null,"abstract":"<div><h3>Introduction</h3><div>The wisdom teeth usually erupt at the age of 17–25 years leading to the risk of pericoronitis, caries, periodontitis, anterior crowding of teeth and cyst development. Previous studies have reported that the third molar infection is more associated with the age group of 26–35 years and is more commonly reported in the female gender.</div></div><div><h3>Aims</h3><div>Hence, the aim was to assess knowledge regarding third molar infections among women degree college students.</div></div><div><h3>Method</h3><div>ology: This cross-sectional study was conducted among 600 students in three women's degree colleges. Awareness and oral health practices were recorded using a supervised self-administered structured questionnaire. The third molar status was recorded by two calibrated examiners. Descriptive statistics, ANOVA, independent T-test and chi-square tests were used to interpret the data.</div></div><div><h3>Results</h3><div>The prevalence of dental caries and pericoronitis with respect to the third molar was 22.5 % and 10.5 % respectively. 63 % expressed no awareness regarding problems associated with third molars. Only 27.2 % were aware of the impact of third molar infection on general health. Mean awareness score was 3.22 ± 1.60. There was a significant increase in awareness of third molars with age. Presence of dental caries significantly affects knowledge score, with those having dental caries (3.68) having a higher score.</div></div><div><h3>Conclusion</h3><div>This study emphasizes the importance of comprehensive oral health education programs tailored to the needs of students in different educational institutions. By raising awareness about third-molar-related complications and promoting regular dental check-ups, these programs can contribute to improving oral health outcomes among young adults.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 141-145"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive characterization of tobacco-induced changes in enamel surface topography 烟草诱导牙釉质表面形貌变化的综合表征。
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.007
Tamanna Kaur , Ramya Ramadoss , Nitya Krishnasamy , Sandhya Sundar , Suganya Panneer Selvam , Hema Shree K
{"title":"Comprehensive characterization of tobacco-induced changes in enamel surface topography","authors":"Tamanna Kaur ,&nbsp;Ramya Ramadoss ,&nbsp;Nitya Krishnasamy ,&nbsp;Sandhya Sundar ,&nbsp;Suganya Panneer Selvam ,&nbsp;Hema Shree K","doi":"10.1016/j.jobcr.2024.12.007","DOIUrl":"10.1016/j.jobcr.2024.12.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Enamel translucency, essential for the aesthetic appeal of teeth, is primarily determined by its thickness, quality, and refractive index. Several factors, including age, genetics, diet, oral hygiene practices, fluoride exposure, and acidic challenges, can influence enamel translucency. Tobacco use, in particular, leads to significant alterations in enamel appearance by penetrating its micropores, causing yellowing and browning. Prolonged exposure to tobacco results in demineralization, increasing enamel porosity and reducing its translucency. Over time, this exposure leads to permanent discoloration and structural degradation, rendering teeth dull and opaque. To assess these changes, various methods such as visual examinations, digital photography, spectrophotometry, stylus profilometry, and atomic force microscopy (AFM) are utilized.</div></div><div><h3>Materials and methods</h3><div>This study analyzed human enamel samples, including one unstained sample (Grade 0) and three tobacco-stained samples (Grades 1–3) according to Modified Lobene Stain Index (MLSI), to investigate the impact of tobacco exposure on enamel structure. The samples were thoroughly cleaned and dried to ensure accurate results. High-resolution AFM imaging was employed to assess surface roughness, porosity, and microstructural changes induced by tobacco staining. A stylus profilometer was used to trace the surface topography, providing detailed measurements of surface irregularities. Additionally, a spectrophotometer was utilized to evaluate the optical properties of the enamel, focusing on changes in translucency and light absorption due to tobacco exposure.</div></div><div><h3>Results</h3><div>AFM analysis revealed a clear progression of enamel surface roughness from Grade 0 to Grade 3. The Sa and Sq values increased significantly with the severity of tobacco staining, indicating greater surface degradation. The stylus profilometer data corroborated these findings, with rising Ra values as the degree of staining intensified, highlighting the topographical alterations caused by tobacco exposure. Spectrophotometric analysis further demonstrated a decrease in enamel reflectance and an increase in light absorption from mild to severe staining, underscoring the detrimental optical effects of tobacco on enamel.</div></div><div><h3>Conclusion</h3><div>The combined use of AFM, stylus profilometry, and spectrophotometry provided a comprehensive assessment of the impact of tobacco staining on enamel translucency and surface roughness. The findings show that as staining severity increases, enamel translucency diminishes, and surface roughness worsens. These alterations not only affect the aesthetic appearance of teeth but also have potential implications for enamel functionality and long-term oral health.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 97-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease 茎突表型和动脉粥样硬化斑块:甲状旁腺疾病的影像学和骨密度评估。
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.001
Adilia Mirela Pereira Lima Cid , Davi de Sá Cavalcante , Marcela Lima Gurgel , Ana Carolina Saraiva , Ana Alicia Sales Ricardo , Lúcio Mitsuo Kurita , Paulo Goberlânio de Barros Silva , Catarina Brasil d’Alva , Ana Rosa Pinto Quidute , Fabio Wildson Gurgel Costa
{"title":"Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease","authors":"Adilia Mirela Pereira Lima Cid ,&nbsp;Davi de Sá Cavalcante ,&nbsp;Marcela Lima Gurgel ,&nbsp;Ana Carolina Saraiva ,&nbsp;Ana Alicia Sales Ricardo ,&nbsp;Lúcio Mitsuo Kurita ,&nbsp;Paulo Goberlânio de Barros Silva ,&nbsp;Catarina Brasil d’Alva ,&nbsp;Ana Rosa Pinto Quidute ,&nbsp;Fabio Wildson Gurgel Costa","doi":"10.1016/j.jobcr.2024.12.001","DOIUrl":"10.1016/j.jobcr.2024.12.001","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to assess the styloid process (TBSP) phenotype and to identify suggestive images of calcified atheromatous plaques (CAP) in panoramic radiographs of patients with primary hyperparathyroidism (PHPT) and post-surgical hypoparathyroidism (hypoPT). Additionally, it aimed to analyze the association between the bone mineral status of patients with parathyroid diseases and the radiographic findings.</div></div><div><h3>Material and methods</h3><div>A cross-sectional case-control study was conducted with individuals diagnosed with PHPT (n = 25) and post-surgical hypoPT (n = 25). A control group (n = 50) comprised individuals without parathyroid gland disorders. Panoramic radiographs were utilized for both quantitative (length) and qualitative (mineralization patterns) evaluation of the TBSP, as well as for assessing the prevalence of CAP.</div></div><div><h3>Results</h3><div>The frequency of TBSP exceeding 30 mm was significantly higher in the PHPT and post-surgical hypoPT groups compared to the control group. CAP occurred more frequently in the PHPT group. Cases of low bone mineral density (BMD) were associated with PHPT. In the PHPT group, low BMD was linked to an increased average TBSP length (p = 0.025) and a higher frequency of elongated TBSP (p = 0.022). Multivariate analysis revealed an inverse relationship between the T-score of the femoral neck and TBSP length in the PHPT group (p = 0.028).</div></div><div><h3>Conclusions</h3><div>Compared to the control group, individuals with PHPT and post-surgical hypoPT showed distinct imaging findings related to TBSP and CAP. Individuals with PHPT and low BMD showed a higher frequency of elongated TBSP.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 88-96"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bibliometric analysis of 100 most cited papers on oral proliferative verrucous leukoplakia 口腔增殖性疣状白斑100篇被引文献计量分析。
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.11.008
Namrata Sengupta , Gargi S. Sarode , Sachin C. Sarode
{"title":"Bibliometric analysis of 100 most cited papers on oral proliferative verrucous leukoplakia","authors":"Namrata Sengupta ,&nbsp;Gargi S. Sarode ,&nbsp;Sachin C. Sarode","doi":"10.1016/j.jobcr.2024.11.008","DOIUrl":"10.1016/j.jobcr.2024.11.008","url":null,"abstract":"<div><h3>Background</h3><div>Bibliometric analysis of highly cited papers in a particular discipline brings forward the impactful papers published, the significant journals and the researchers in the field. These studies help in identifying research trends and research lacunae in the field, thus guiding the future research works. Oral proliferative verrucous leukoplakia (OPVL) is a challenging lesion with no uniform diagnostic criteria. Thus, bibliometric analysis of published papers in this field will help researchers and clinicians to get an overview of the research trends and the research lacunae associated with OPVL.</div></div><div><h3>Method</h3><div>A search was done with help of Scopus database in November 2023. The articles on OPVL were retrieved and reviewed thoroughly. The bibliometric data was also recorded.</div></div><div><h3>Results</h3><div>The impactful research papers were published in the time span of 1985–2022 with maximum output being in the decade 2011–2020. The highest citation received was 297 and the least was 4 (mean citations 34 ± 42.57). These papers were published in 47 different journals. Seven authors contributed 5 or more papers each. United States had the major contribution of papers (n = 28). There were 71 articles and 18 review papers in the top list.</div></div><div><h3>Conclusion</h3><div>This bibliometric and citation analysis of OPVL research papers will guide researchers and clinicians in understanding the research traits and thus, may help in making OPVL a less challenging lesion.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 41-47"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of bone healing in trabeculae structure of mandibular corpus and angulus fracture patients with fractal dimension analysis 用分形维数分析评价下颌骨骨小梁结构及骨角骨折患者的骨愈合
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.015
Poerwati Soetji Rahajoe , Hendra Sukawijaksa , Pingky Krisna Arindra , Silviana Farrah Diba
{"title":"Evaluation of bone healing in trabeculae structure of mandibular corpus and angulus fracture patients with fractal dimension analysis","authors":"Poerwati Soetji Rahajoe ,&nbsp;Hendra Sukawijaksa ,&nbsp;Pingky Krisna Arindra ,&nbsp;Silviana Farrah Diba","doi":"10.1016/j.jobcr.2024.12.015","DOIUrl":"10.1016/j.jobcr.2024.12.015","url":null,"abstract":"<div><h3>Background</h3><div>Fractures of the mandibular corpus and angulus are affected by different forces result from different strength of the muscles that influenced them. Therefore, it is presumed that there is a different in healing rate. Fractal dimension radiologic analysis assesses the trabecular pattern, due to it can be used to observe the healing process of bone fractures.</div></div><div><h3>Purpose</h3><div>The study aimed to compare the healing process of mandibular corpus and angulus fractures with fractal dimension analysis (FD) of trabecular patterns on panoramic radiographs through ImageJ software as consideration to determine mastication loading time.</div></div><div><h3>Methods</h3><div>This retrospective cross-sectional study observed medical records and panoramic radiographs of patients with a diagnosis of corpus and or mandibular angulus fractures undergoing open reduction (ORIF) 1 plate treatment combined with maxillomandibular fixation (MMF) at Hospital in 2017–2023. Observations were carried out on postoperative 1st day, 2nd week, 8–13th week and &gt;13th week respectively.</div></div><div><h3>Results</h3><div>Twenty-five subjects who met the inclusion requirements were involved in the study. The results of Two-Way ANOVA statistical test and Fisher's LSD post-hoc showed that the FD values of corpus fracture were significantly greater than that of mandibular angulus with p 0.000 (H1), 0.003 (H2), 0.03 (H3), 0.000 (H4) respectively. In both groups of mandibular corpus and angulus fractures, there was a significant effect of time with p = 0.00 in each group. The longer the observation time, the more trabeculae patterns were formed in the healing process of corpus and angulus fractures.</div></div><div><h3>Conclusion</h3><div>Post ORIF observation of corpus fracture shows a greater trabecula formation value which indicates faster healing when compared to mandibular angulus fracture.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 205-211"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143177403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of chewing and swallowing in post mandibular resection patients with no bony reconstruction – A cross sectional study 评估下颌切除术后无骨重建患者咀嚼和吞咽-一项横断面研究
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.014
Irfana Sithara Cholayil, Reena Rachel John, Narendran Achuthan
{"title":"Assessment of chewing and swallowing in post mandibular resection patients with no bony reconstruction – A cross sectional study","authors":"Irfana Sithara Cholayil,&nbsp;Reena Rachel John,&nbsp;Narendran Achuthan","doi":"10.1016/j.jobcr.2024.12.014","DOIUrl":"10.1016/j.jobcr.2024.12.014","url":null,"abstract":"<div><h3>Introduction</h3><div>The intricate process of chewing and swallowing is compromised following mandibular resection. An evaluation of chewing and swallowing is crucial to comprehend the quality of life following surgery in cases when bone repair was not performed. The purpose of this study is to evaluate chewing and swallowing in mandibulectomy patients without bony reconstruction.</div></div><div><h3>Material and method</h3><div>This study involved ten patients, including four with H defects, three with L defects, and three with LC defects, after a one-year postop period. Using Robbin's penetration aspiration scale, video fluoroscopy was used to evaluate swallowing. Using a functional oral intake scale, chewing was assessed. Fischer's exact test was used for statistical analysis.</div></div><div><h3>Results</h3><div>Robbin's penetration aspiration scale score of 1 was noted in all 10 patients. According to FOIS, 50 % of patients with H defect scored 4, and 66.7 % of those with L defect scored 6. The results were not significant when the scores were correlated with the type of defect.</div></div><div><h3>Conclusion</h3><div>Mandibular surgical defects which were not reconstructed with bone were shown to affect the quality of life in our study. Chewing efficiency was poorest in patients with H defect. Swallowing efficiency was not affected adversely in this group of patients.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 159-162"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143177745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of osteoblast response to polyacrylonitrile infused nano-curcumin coated on titanium discs: Invitro study cell culture experimental study 成骨细胞对聚丙烯腈注入纳米姜黄素包被钛片的反应评价:体外细胞培养实验研究。
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.003
Shilpi Gupta, N. Gopi Chander, Aravind Bhat, K.V. Anitha
{"title":"Evaluation of osteoblast response to polyacrylonitrile infused nano-curcumin coated on titanium discs: Invitro study cell culture experimental study","authors":"Shilpi Gupta,&nbsp;N. Gopi Chander,&nbsp;Aravind Bhat,&nbsp;K.V. Anitha","doi":"10.1016/j.jobcr.2024.12.003","DOIUrl":"10.1016/j.jobcr.2024.12.003","url":null,"abstract":"<div><h3>Purpose</h3><div>The study evaluated the influence of titanium discs, coated with polyacrylonitrile infused curcumin nanofibers on osteoblast activity.</div></div><div><h3>Materials and methods</h3><div>The titanium discs were coated with polyacrylonitrile nanofibers infused with curcumin. MG-63 cell lines were utilized for cell culture to assess osteoblast morphology upon exposure of curcumin on titanium discs. SEM comparison was made. Lactate Dehydrogenase (LDH) activity was measured after 2 and 7 days and the Alkaline Phosphatase (ALP) activity of the cells was quantified.</div></div><div><h3>Results</h3><div>The results indicated that the coating had a notable impact on mineralization, LDH and ALP activities. Significant differences were observed between uncoated and coated samples. The SEM analysis indicated that curcumin enhanced bone growth when the Ti discs coated with curcumin are implanted in the bone.</div></div><div><h3>Conclusion</h3><div>Polyacrylonitrile infused nano-curcumin fibers coated on titanium discs potentially enhanced osteoblast response and mineralization.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 57-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11681823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study 正颌手术对唇腭裂患者咀嚼功能的长期影响:一项前瞻性研究。
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.11.002
Patricia Martins Bueno , Paulo Alceu Kiemle Trindade , Laís Hollara Medeiros , Leide Vilma Fidélis da Silva , Ivy Kiemle Trindade-Suedam
{"title":"Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study","authors":"Patricia Martins Bueno ,&nbsp;Paulo Alceu Kiemle Trindade ,&nbsp;Laís Hollara Medeiros ,&nbsp;Leide Vilma Fidélis da Silva ,&nbsp;Ivy Kiemle Trindade-Suedam","doi":"10.1016/j.jobcr.2024.11.002","DOIUrl":"10.1016/j.jobcr.2024.11.002","url":null,"abstract":"<div><h3>Objective</h3><div>To prospectively evaluate the long-term effects of orthognathic surgery on masticatory function in individuals with repaired complete cleft lip and palate and to compare the results with a control group.</div></div><div><h3>Material and methods</h3><div>A total of 40 individuals were prospectively analyzed before (PRE-ORTHOG) and approximately 12 months after orthognathic surgery (POST-ORTHOG). The participants were divided into two groups: 1) Cleft Lip and Palate Group (CLP): 20 adults with CLP undergoing orthognathic surgery (14 ♂, 6 ♀, age 24 ± 3 years), and 2) Control Group (CON): 20 paired adults with Angle Class I skeletal pattern who had never undergone orthognathic surgery (14 ♂, 6 ♀, age 25 ± 5 years). Three variables were evaluated: 1) Bite Force (BF) (measured in Newtons – N) presented as the average of the bite force from the right and left molars (<span><math><mrow><mover><mi>x</mi><mo>‾</mo></mover></mrow></math></span> RM + LM), using a gnathodynamometer (IDDK Kratos), 2) Masticatory Efficiency (ME) (ranging from 0 to 1, with values closer to 1 indicating poorer efficiency), assessed through a dual-color masticatory gum test analyzed visually and optoelectronically (ViewGum©), and 3) Masticatory Capacity (MC): patient-reported ability to chew, rated on a two-point scale (P/R = poor to reasonable, G/O = good to optimal).</div></div><div><h3>Results</h3><div>In the PRE-ORTHOG phase, the BF for the CLP group (<span><math><mrow><mover><mi>x</mi><mo>‾</mo></mover></mrow></math></span> RM + LM = 285 ± 141) was significantly lower compared to the CON group (<span><math><mrow><mover><mi>x</mi><mo>‾</mo></mover></mrow></math></span> RM + LM = 524 ± 202). In the POST-ORTHOG phase, the CLP group (<span><math><mrow><mover><mi>x</mi><mo>‾</mo></mover></mrow></math></span> RM + LM = 373 ± 129) showed significant improvements in BF in relation to the PRE-ORTHOG phase, with values similar to those of the CON group. Masticatory efficiency improved significantly in the POST-ORTHOG phase (0.222 ± 0.071) compared to PRE-ORTHOG (0.470 ± 0.126) in the CLP group, while PRE-ORTHOG values were worse than those of the CON group (0.148 ± 0.050). Furthermore, 45 % of CLP participants reported P/R MC before surgery, while none reported this after surgery, a statistically significant improvement. The POST-ORTHOG MC results for CLP participants were comparable to the CON group, with 100 % reporting G/O MC after surgery.</div></div><div><h3>Conclusions</h3><div>Overall, the group with CLP demonstrated impaired masticatory function in the preoperative phase compared to the control group across all variables analyzed. Orthognathic surgery improves masticatory function in patients with CLP, with postoperative parameters comparable to those of the control group.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 33-40"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomized clinical trial comparing retention of complete dentures and oral health quality of life of patients with conventional and bioelectric impressions 一项比较常规和生物电印模患者全口义齿固位和口腔健康生活质量的随机临床试验。
Journal of oral biology and craniofacial research Pub Date : 2025-01-01 DOI: 10.1016/j.jobcr.2024.12.006
Sapna Rani, Pankaj Dhawan, Vidushi Saxena
{"title":"A randomized clinical trial comparing retention of complete dentures and oral health quality of life of patients with conventional and bioelectric impressions","authors":"Sapna Rani,&nbsp;Pankaj Dhawan,&nbsp;Vidushi Saxena","doi":"10.1016/j.jobcr.2024.12.006","DOIUrl":"10.1016/j.jobcr.2024.12.006","url":null,"abstract":"<div><h3>Aim</h3><div>The aim of the present study was to comparatively evaluate the retention of complete dentures and oral health-related quality of life (OHRQoL) of patients with conventional and bioelectric impressions or transcutaneous electric nerve stimulation (TENS).</div></div><div><h3>Materials and methods</h3><div>A total of thirty (n = 30) completely edentulous patients were randomly distributed into two groups: Group-C (n = 15) (Conventional) and Group-T (n = 15) (bioelectric). In Group C, border molding was performed using the manual manipulation of borders, and the final impression was made using zinc-oxide eugenol. In Group T, border molding and final impression were performed with the TENS application. Dentures were fabricated, and retention was evaluated with a digital gauge. OHRQoL was assessed at insertion and after three months of follow-up using the Oral Health Impact Profile Edentulous in Hindi (OHIP-Edent-H) questionnaire. A two-way ANOVA test was used for the significance level (<em>P</em> &lt; 0.05). Student t-test was used for intergroup comparison, and paired <em>t</em>-test was used for intragroup comparison of OHRQoL.</div></div><div><h3>Results</h3><div>There was no significant difference in the retention of maxillary and mandibular dentures fabricated with both techniques (<em>P</em> = 0.283, <em>P</em> = 0.682). Although, OHRQoL increased significantly in both groups at follow-up (<em>P</em> = 0.001). However, at follow-up, the Functional Limitation (FL) domain was significantly better in the conventional group.</div></div><div><h3>Conclusions</h3><div>Although, there was no significant difference in retention and OHRQoL between both groups. However, more clinical trials with large samples and longer follow-ups are required to reach a conclusive result.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 1","pages":"Pages 103-107"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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