Effect of cryotherapy, laser therapy and intraligamentary dexamethasone injection on post-treatment pain after single visit RCT–A double-blinded, randomized placebo-controlled trial

Q1 Medicine

Journal of oral biology and craniofacial research Pub Date : 2025-02-09 DOI:10.1016/j.jobcr.2025.01.005

Dr Sana Fatima , Dr Sonali Taneja , Dr Vivek Aggarwal , Dr Akriti Dheer , Dr Punya Taneja

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Abstract

Aim

This study designed to evaluate the effect of adjuvant therapies on the intensity of post-treatment pain after single-visit RCT in molars with symptomatic apical periodontitis.

Method

ology: This trial was reported according PRIRATE 2020 guidelines and registered with CTRI/2019/03/018,153.100 patients diagnosed with symptomatic apical periodontitis with a preoperative pain allocated to 4 groups,Group-1: placebo,Group-2:Intraligamentary injection of dexamethasone, Group-3:cryotherapy, Group-4: laser therapy. Patients were instructed to record postoperative pain intensity and intake of analgesics after 6,12,24,48 & 72 h. Intergroup pain intensity was tested by using the Kruskal-Wallis test. The need for painkillers between groups was analyzed using Chi-square test. P value of <0.05 was considered statistically significant.

Results: Patients in the placebo group exhibited higher intensity. Group 3 showed lesser pain at all-time intervals.

Conclusion

All the adjuvant pain management therapies reduced the intensity of postoperative pain and the frequency of intake of analgesics.

Abstract Image

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冷冻治疗、激光治疗和韧带内注射地塞米松对单次访视后疼痛的影响

目的探讨辅助治疗对症状性根尖牙炎磨牙单次随机对照试验治疗后疼痛强度的影响。方法：本试验根据PRIRATE 2020指南进行报道，并在CTRI/ 2019/03/018153.100例诊断为症状性根尖牙周炎并伴有术前疼痛的患者注册，分为4组，1组：安慰剂，2组：韧带内注射地塞米松，3组：冷冻治疗，4组：激光治疗。患者被指示在术后6、12、24、48和amp后记录疼痛强度和镇痛药的摄入量；72h。采用Kruskal-Wallis检验各组间疼痛强度。使用卡方检验分析各组间止痛药需求。P值为<；0.05认为有统计学意义。结果：安慰剂组患者表现出更高的强度。第三组在同一时间间隔表现出较轻的疼痛。结论所有辅助疼痛管理治疗均能降低术后疼痛强度和镇痛药物的使用频率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of oral biology and craniofacial research Medicine-Otorhinolaryngology

CiteScore

4.90

自引率

0.00%

发文量

133

审稿时长

167 days

期刊介绍： Journal of Oral Biology and Craniofacial Research (JOBCR)is the official journal of the Craniofacial Research Foundation (CRF). The journal aims to provide a common platform for both clinical and translational research and to promote interdisciplinary sciences in craniofacial region. JOBCR publishes content that includes diseases, injuries and defects in the head, neck, face, jaws and the hard and soft tissues of the mouth and jaws and face region; diagnosis and medical management of diseases specific to the orofacial tissues and of oral manifestations of systemic diseases; studies on identifying populations at risk of oral disease or in need of specific care, and comparing regional, environmental, social, and access similarities and differences in dental care between populations; diseases of the mouth and related structures like salivary glands, temporomandibular joints, facial muscles and perioral skin; biomedical engineering, tissue engineering and stem cells. The journal publishes reviews, commentaries, peer-reviewed original research articles, short communication, and case reports.