Journal of Medical Primatology最新文献

{"title":"Determination of Minimum Alveolar Concentrations of Isoflurane and Effective Plasma Concentration of Propofol in Common Marmosets (Callithrix jacchus)","authors":"Kanako Muta,&nbsp;Makoto Koizumi,&nbsp;Takako Miyabe-Nishiwaki,&nbsp;Yusuke Sotomaru,&nbsp;Asako Nobukiyo,&nbsp;Hiroki Ohta,&nbsp;Hirotaka James Okano,&nbsp;Masatoshi Kamata,&nbsp;Dai Nagakubo,&nbsp;Ryohei Nishimura","doi":"10.1111/jmp.70006","DOIUrl":"https://doi.org/10.1111/jmp.70006","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Common marmosets (<i>Callithrix jacchus</i>) have been widely used as laboratory animals; However, limited sedation and anesthetic protocols have yet to be established. In this study, the minimum alveolar concentration of an inhalant (isoflurane) and effective predicted plasma concentration of an injectable anesthetic (propofol) were measured for optimization of sedation and anesthetic protocols in marmosets.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The minimum alveolar concentrations (MACs) for several stimulations (nociceptive stimulation, endotracheal intubation, and non-painful direct stimulation), MAC-noci, MAC-extb, and MAC-awake, respectively, were measured for isoflurane with the up-and-down method from four healthy marmosets. Predicted plasma concentrations 50 (Cp50s), which are equivalent to MACs of isoflurane, Cp50-noci, Cp50-extb, and Cp50-awake, respectively, were measured for propofol.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>MAC-noci and MAC-extb of isoflurane in marmosets were 1.91% and 1.38%, respectively. MAC-awake was not determined owing to technical difficulties. Cp50-noci, Cp50-extb, and Cp50-awake were 9.45, 7.21, and 3.54 μg/mL, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The obtained results refined existing isoflurane and propofol for sedation and anesthesia in marmosets.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.70006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Field-Based Assessment of Disease Symptoms and Physical Wounds in Endangered Shennongjia Golden Snub-Nosed Monkey (Rhinopithecus roxellanahubeiensis) Colonies: Implications for Conservation","authors":"Muhammad Zaman,&nbsp;Fangyi Wei,&nbsp;Mei Chen,&nbsp;Luwei Chen,&nbsp;Hui Yao,&nbsp;Zuofu Xiang","doi":"10.1111/jmp.70003","DOIUrl":"https://doi.org/10.1111/jmp.70003","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Globally, approximately 60% of primate taxa are in danger of extinction and the population of 75% of primate species are declining in their natural habitats. The Endangered <i>R. roxellana hubeiensis</i> monkeys in Shennongjia National Park face threats due to their limited genetic diversity and restricted habitat.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Our study aimed to assess the health of these monkeys through focal animal sampling observations of 90 individuals from June 2023 to July 2024. Additionally, we compared the prevalence of health concerns on days with and without snow. We identified health issues in 32 individuals (46%), including wounds, signs suggesting disease, and deaths.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Nine lactating females one juvenile and one infant had eye injuries. We noticed three females and one male exhibiting symptoms of eye diseases. We observed that one adult male and three females showed signs of respiratory disease, while three females exhibited signs of skin disease. We found that one adult male and three females indicated signs of respiratory disease and three females showed signs of skin disease. We found that seven monkeys of different ages, including adults, juveniles and infants, died from injuries, diseases and unknown causes. Respiratory and skin disease symptoms were more common on snowy days than on non-snowy days. Additionally, physical and eye injuries were also more prevalent on snowy days.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In general, our study investigated the health status of Shennongjia golden snub-nosed monkeys and found signs of disease, wounds, and death. Our study also highlighted health issues in monkeys, which can help guide conservation efforts to ensure their survival in their natural habitats.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143431248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence of Toxoplasma gondii in Three Tamarin Species (Saguinus geoffroyi, Saguinus oedipus, and Leontocebus fuscicollis) Ex Situ in Colombia","authors":"Karime Angarita-Corzo,&nbsp;Lina M. Henao-Montoya,&nbsp;Mónica Franco-G,&nbsp;Henrique G. Riva,&nbsp;Nathalia M. Correa-Valencia","doi":"10.1111/jmp.70005","DOIUrl":"https://doi.org/10.1111/jmp.70005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Toxoplasmosis, caused by <i>Toxoplasma gondii</i>, is a zoonotic disease affecting public health and wildlife conservation, including nonhuman primates. This study evaluated the presence of <i>T. gondii</i> in three neotropical tamarin species (<i>Leontocebus fuscicollis, Saguinus geoffroyi</i> and <i>Saguinus oedipus</i>) at Barranquilla Zoo, Colombia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis (2017–2022) was conducted on 17 tamarins. Clinical evaluations and blood samples were used to detect IgG antibodies via latex agglutination test. Necropsies and histopathological analyses were used to assess organ lesions associated with <i>T. gondii.</i></p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In 2017, 35% (6/17) of the participants tested seropositive, increasing to 100% (13/13) by 2022. Antibody titer fluctuations were noted, with significant increases in female <i>S. oedipus</i>. Four deaths occurred, two linked to active or chronic infections. Stray cats and rodents in the zoo were identified as possible transmission vectors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study highlights <i>T. gondii</i> exposure to tamarins, associated mortality, and diagnostic challenges. Recommendations include stray cat management, pest control, and the exploration of vaccines to reduce transmission risks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143431247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Epididymo-Orchitis Caused by Escherichia coli in a Rhesus Monkey","authors":"Heling Li,&nbsp;Long Zhang,&nbsp;Hong Wang","doi":"10.1111/jmp.70004","DOIUrl":"https://doi.org/10.1111/jmp.70004","url":null,"abstract":"<div>\u0000 \u0000 <p>Epididymo-orchitis is characterized by painful swelling and inflammation of the epididymis and testes. A 4-year-old male rhesus monkey has clinical manifestations including anorexia, weakness, as well as redness and swelling of the right testis and epididymis. Bacterial culture of the urine was positive for <i>Escherichia coli</i>. Due to the antibiotic treatment being ineffective, the animal underwent a right orchiectomy. Postoperative histopathology confirmed necrosis and significant inflammatory cell infiltration, indicating severe acute epididymo-orchitis (EO) caused by <i>E. coli</i> infection in the rhesus monkey. After surgical treatment and postoperative care, the animal survived. To our knowledge, this represents the first report of acute EO caused by <i>E. coli</i> in a rhesus monkey. These findings not only enhance our understanding of EO in NHPs but also provide a reference for further biomedical studies of EO induced by <i>E. coli.</i></p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison Between Indirect Fluorescent Antibody Test and Modified Agglutination Test for Detecting Anti-Toxoplasma gondii IgG Antibodies in Neotropical Primates","authors":"Nycolas Octavio Ribeiro Carvalho,&nbsp;Raquel Cuba Gaspar,&nbsp;Suellen Gonçalves Lima,&nbsp;Dayane da Silva Zanini,&nbsp;Nássarah Jabur Lot Rodrigues,&nbsp;Victor Yunes Guimarães,&nbsp;Aristeu Vieira da Silva,&nbsp;Sheila Canevese Rahal,&nbsp;Anna Luisa Pizzaia Henrique,&nbsp;Felipe Fornazari,&nbsp;Helio Langoni","doi":"10.1111/jmp.70002","DOIUrl":"10.1111/jmp.70002","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p><i>Toxoplasma gondii</i> is a zoonotic parasite with a great impact on the health of Neotropical primates (NP). The aim of this study was to compare the agreement between the immunofluorescent antibody test (IFAT) and the modified agglutination test (MAT) to detect IgG anti-<i>T</i>. <i>gondii</i> antibodies in NP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Convenience serum samples of 77 animals were tested by IFAT and MAT according to standard protocols, and the agreement between results was analyzed using McNemar's <i>χ</i>² test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The samples included 30 red-handed howlers (<i>Alouatta belzebul</i>), 24 brown howler monkeys (<i>Alouatta guariba</i>), 22 capuchin monkeys (<i>Sapajus nigritus</i>), and one wedge-capped capuchin (<i>Cebus olivaceous</i>). Overall prevalence was 25.9% (<i>n</i> = 20), with three animals positive by IFAT and 20 positives by MAT. The agreement between tests was low (Kappa = 0.21).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The results indicated that IFAT and MAT are not comparable to assess qualitatively anti-<i>T</i>. <i>gondii</i> IgG serum antibodies in the studied species.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disseminated Lichtheimia sp. Infection in a Buff-Headed Capuchin (Sapajus xanthosternos)","authors":"Fernanda C. Rocha,&nbsp;Asheley Henrique B. Pereira,&nbsp;Davi S. Leal,&nbsp;Silvia B. Moreira,&nbsp;Alcides Pissinatti,&nbsp;Fernanda H. Maruyama,&nbsp;Luciano Nakazato,&nbsp;Valéria Dutra,&nbsp;Daniel G. Ubiali","doi":"10.1111/jmp.70000","DOIUrl":"10.1111/jmp.70000","url":null,"abstract":"<div>\u0000 \u0000 <p>A clinicopathologic picture caused by <i>Lichtheimia</i> sp. in a 33-year-old male <i>Sapajus xanthosternos</i> kept in a conservationist center is described. Acute apathy, vomiting, fever, and polydipsia were associated with pneumonia, enteritis, and gastritis presenting fibrinoid vasculitis containing hyphae. The fungi were demonstrated molecularly, highlighting the spontaneous disease in primates.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 6","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronous Pleural and Peritoneal Mesothelioma in a Free-Ranging Capuchin Monkey (Sapajus libidinosus)","authors":"Isabel Luana de Macêdo,&nbsp;Davi Emanuel Ribeiro de Sousa,&nbsp;Yasmin Nunes Godoy da Fonseca,&nbsp;Liz de Albuquerque Cerqueira,&nbsp;Ana Lívia Vasconcelos de Sousa,&nbsp;Cristiano Barros de Melo,&nbsp;Eduardo Mauricio Mendes de Lima,&nbsp;Márcio Botelho de Castro","doi":"10.1111/jmp.70001","DOIUrl":"10.1111/jmp.70001","url":null,"abstract":"<div>\u0000 \u0000 <p>A free-ranging capuchin monkey developed a synchronous biphasic pleural and peritoneal mesothelioma, a rare form of this tumor. Exophytic nodules were dispersed over the serosal surfaces, showing marked microscopical malignant features composed of both epithelioid and spindeloid neoplastic cells immunopositive for Pan-Cytokeratin, Cytokeratin 5/6, Vimentin, WT-1, and D2-40.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 6","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reports of Corneal Opacity in Wild Andean Night Monkeys (Aotus lemurinus) in the Colombian Andes","authors":"Silvia Juliana Ruiz-Lozano,&nbsp;Gilder Esteban González-Montenegro,&nbsp;Sebastián O. Montilla","doi":"10.1111/jmp.12743","DOIUrl":"10.1111/jmp.12743","url":null,"abstract":"<div>\u0000 \u0000 <p>Morphological abnormalities are rarely reported in night monkeys; in particular, eye problems in wild individuals are relatively rare in the literature. We present for the first time a record of corneal opacity in two wild individuals of the species <i>Aotus lemurinus</i> in the Andean region of Colombia. In this study, we found cases of corneal opacity probably associated with infectious and contagious processes, injuries resulting from attacks, the age of the individuals, and the health status of the groups in wildlife. We encourage researchers to report their observations of wild primates with ocular abnormalities, as this information could be useful in estimating rates of occurrence and addressing questions associated with the physiological status, social behavior of the species, and their effects on natural populations.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 6","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bertiella mucronata in Black-and-Gold Howler Monkey (Alouatta caraya) in Minas Gerais State, Brazil","authors":"Gabriele Zaine Teixeira Debortoli,&nbsp;Victor Luiz Gomes-Batista,&nbsp;Cibelli Silva Ribeiro,&nbsp;Dirceu Guilherme de Souza Ramos,&nbsp;Iago de Sá Moraes,&nbsp;Maíra Sales Castilho,&nbsp;Leticia Gomes Zanfagnini,&nbsp;Ramiro das Neves Dias Neto,&nbsp;Carlos Augusto dos Santos Sousa,&nbsp;Thaís Rabelo Santos-Doni","doi":"10.1111/jmp.12744","DOIUrl":"10.1111/jmp.12744","url":null,"abstract":"<div>\u0000 \u0000 <p>This is the first reported case of <i>Bertiella mucronata</i> infection in a black-and-gold howler monkey (<i>Alouatta caraya</i>) in Brazil. The present study confirms the widespread of <i>B. mucronata</i> in South America and suggest that black-and-gold howler monkeys may serve as viable reservoirs for <i>B. mucronata</i>.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 6","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Gut Microbiome of Malaysia's Colobine Monkeys : Insights into Health and Evolution","authors":"Abd Rahman Mohd-Ridwan,&nbsp;Badrul Munir Md-Zain,&nbsp;Mohd Faudzir Najmuddin,&nbsp;Nursyuhada Othman,&nbsp;Hidayah Haris,&nbsp;Nur Hartini Sariyati,&nbsp;Ikki Matsuda,&nbsp;Boo Sook Yee,&nbsp;Yiling Lee,&nbsp;Siew Fen Lye,&nbsp;Muhammad Abu Bakar Abdul-Latiff","doi":"10.1111/jmp.12742","DOIUrl":"10.1111/jmp.12742","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Colobines are primarily leaf-eating primates, depend on microbiota of gastrointestinal tracts for food digestion. However, the gut microbiota of Malaysia's colobines specifically langurs remains unstudied.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Aims&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Hence, we aim to analyze the fecal microbiomes of Malaysia's langurs using &lt;i&gt;Presbytis femoralis&lt;/i&gt;, &lt;i&gt;Presbytis robinsoni&lt;/i&gt;, &lt;i&gt;Trachypithecus obscurus&lt;/i&gt;, and &lt;i&gt;Trachypithecus cristatus&lt;/i&gt; from various landscapes as models.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Material and Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We collected samples from all four species across several areas in Peninsular Malaysia and performed 16S ribosomal RNA gene amplicon sequencing using the Illumina sequencing platform.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;&lt;i&gt;Presbytis femoralis&lt;/i&gt; exhibited the highest bacterial diversity, followed by &lt;i&gt;T. obscurus&lt;/i&gt;, &lt;i&gt;T. cristatus&lt;/i&gt;, &lt;i&gt;P. robinsoni&lt;/i&gt; and the lowest, &lt;i&gt;P. siamensis&lt;/i&gt;. Over 11 million operational taxonomic units (OTUs) were identified across Malaysia's langurs spanning 26 phyla, 180 families, and 329 genera of microbes. The OTUs were dominated by Firmicutes, Proteobacteria, and Bacteroidetes. There are 11 genera of pathogenic bacteria were identified across all host species. Nine pathogenic bacterial genera inhabit both &lt;i&gt;T. obscurus&lt;/i&gt;, indicating poor health due to low bacterial diversity and heightened pathogenicity. In contrast, &lt;i&gt;P. robinsoni&lt;/i&gt; with the fewest pathogenic species is deemed the healthiest among Malaysia's langurs.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Discussion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study demonstrates that alterations in diet, behavior, and habitat affect bacterial diversity in Malaysia's langurs' gut microbiota. Even though this is the first comprehensive analysis of langur microbiomes in Malaysia, it is important to note the limitations regarding the number of samples, populations sampled, and the geographical origins and landscapes of these populations. Our results suggest that Malaysia's langurs may harbor pathogenic bacteria, potentially posing a risk of transmission to humans.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This highlights the critical need for the conservation and management of Malaysia's langurs, particularly considering their interactions with humans. This data can serve as a foundation for authorities to inform the public about the origins and significance of animal health and the management of zoonotic diseases.&lt;/p&gt;\u0000 ","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 6","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}