Renal Cell Carcinoma in a Common Marmoset: First Report and a Brief Review of Nonhuman Primate Literature

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Medical Primatology Pub Date : 2025-03-27 DOI:10.1111/jmp.70014

Taysia Battee, Olga Gonzalez, Phil S. Medlin, Edward J. Dick Jr, Vinay Shivanna

引用次数: 0

Abstract

Renal cell carcinoma (RCC) is a malignant form of urogenital cancer that arises from renal tubular epithelial cells. Here, we describe a case of renal cell carcinoma in a common marmoset (Callithrix jacchus). Immunohistochemistry demonstrated positive reactivity for PAX8 and CD10 in the renal neoplasm. We review 115 cases of spontaneous renal tumors in nonhuman primates (NHP) reported in the literature and from the Southwest National Primate Research Center records. Across all NHPs, malignant renal neoplasms were more frequent than benign. There appears to be a male sex predilection for renal tumors in baboons. This is the first reported case of renal cell carcinoma in a marmoset.

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一种普通狨猴的肾细胞癌：首次报道和非人类灵长类动物文献综述

肾细胞癌（RCC）是一种起源于肾小管上皮细胞的泌尿生殖系统恶性肿瘤。在这里，我们描述了一例肾细胞癌在一个普通狨猴（Callithrix jacchus）。免疫组织化学显示PAX8和CD10在肾肿瘤中呈阳性反应。我们回顾了115例非人灵长类动物自发性肾肿瘤（NHP）的文献报道和来自西南国家灵长类动物研究中心的记录。在所有NHPs中，恶性肾肿瘤比良性肾肿瘤更常见。狒狒似乎有雄性对肾脏肿瘤的偏好。这是首例报道的狨猴肾细胞癌病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Primatology 生物-动物学

CiteScore

1.40

自引率

42.90%

发文量

审稿时长

6 months

期刊介绍： The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs. Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.