Victoria D. Silva, Pragathi B. Shridhar, Olga D. Gonzalez, Edward J. Dick Jr., Vinay Shivanna
{"title":"Pseudomonas Infections in the Common Marmoset (Callithrix jacchus): Gross and Histopathological Findings","authors":"Victoria D. Silva, Pragathi B. Shridhar, Olga D. Gonzalez, Edward J. Dick Jr., Vinay Shivanna","doi":"10.1111/jmp.70016","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Common marmosets (<i>Callithrix jacchus</i>) are a New World nonhuman primate (NHP) whose popularity as a research model continues to expand. Marmosets were identified as the predominant NHP species that is susceptible to spontaneous <i>Pseudomonas</i> infections based on a 27-year survey in a primate colony, encompassing several NHP species. 26 common marmosets were retrospectively identified and evaluated for spontaneous <i>Pseudomonas</i> spp. infections. Clinical symptoms included lethargy, weight loss, gastrointestinal issues (diarrhea, bloating, vomiting, poor appetite), increased respiratory effort, and difficulty urinating. Affected organs (larynx, lungs, liver, gallbladder, intestines, colon, uterus, and urinary bladder) appeared discolored, distended, or enlarged. Microscopic findings included inflammatory infiltrates, edema, necrosis, hemorrhage, and pseudomembranous lesions. Only animals with clinical symptoms or gross evidence of bacterial infection were cultured; therefore, the actual incidence of <i>Pseudomonas</i> spp. infections is unknown. We present the common and uncommon lesions associated with <i>Pseudomonas</i> infections in the common marmoset.</p>\n </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 2","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Primatology","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jmp.70016","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Common marmosets (Callithrix jacchus) are a New World nonhuman primate (NHP) whose popularity as a research model continues to expand. Marmosets were identified as the predominant NHP species that is susceptible to spontaneous Pseudomonas infections based on a 27-year survey in a primate colony, encompassing several NHP species. 26 common marmosets were retrospectively identified and evaluated for spontaneous Pseudomonas spp. infections. Clinical symptoms included lethargy, weight loss, gastrointestinal issues (diarrhea, bloating, vomiting, poor appetite), increased respiratory effort, and difficulty urinating. Affected organs (larynx, lungs, liver, gallbladder, intestines, colon, uterus, and urinary bladder) appeared discolored, distended, or enlarged. Microscopic findings included inflammatory infiltrates, edema, necrosis, hemorrhage, and pseudomembranous lesions. Only animals with clinical symptoms or gross evidence of bacterial infection were cultured; therefore, the actual incidence of Pseudomonas spp. infections is unknown. We present the common and uncommon lesions associated with Pseudomonas infections in the common marmoset.
期刊介绍:
The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs.
Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.