Journal of Medical Primatology最新文献

{"title":"Assessment of the Risks of Zoonotic Infection at the Primatology Centre of the Interdisciplinary Medical Research Centre of Franceville in Gabon","authors":"Nzue Nguema Jean,&nbsp;Otsaghe Ekore Désiré,&nbsp;Dibakou Serge Ely,&nbsp;Boundenga Larson,&nbsp;Tsoumbou Thiérry-Audrey,&nbsp;Moussadji Kinga Ivan Cyr,&nbsp;Okomo Nguema Yasmine,&nbsp;Mombo Landry Erik,&nbsp;Pontier Dominique,&nbsp;Ngoubangoye Barthélemy","doi":"10.1111/jmp.12741","DOIUrl":"https://doi.org/10.1111/jmp.12741","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Non-human primate (NHPs) conservation sites could be sites of exchange of pathogens involved in infectious diseases. It is important to assess the potential risks associated with this type of structure. The objective of this study was to carry out a risk assessment of the Primatology Centre housed in the Interdisciplinary Centre for Medical Research of Franceville (CIRMF).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A questionnaire was administered to the centre's staff to assess the risk associated with each workstation, followed by a review of the various pathogens identified in NHPs. The data were analysed using two diagrams: the Kiviat diagram and the Pareto diagram.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Based on our results, a variety of pathogens such as viruses, bacteria and parasites, potentially transmissible to humans, were described in the NHPs at the Primatology Centre of CIRMF. The position most exposed to zoonotic risks was that of animal handlers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The Primatology Centre of CIRMF is a potential transfer site for the transfer of zoonotic agents. To avoid the risk of parasite exchange between staff and animals, the implementation of biosecurity measures is essential.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12741","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142429954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic Measurements of the Hip Joint in Capuchin Monkeys (Sapajus spp.)","authors":"Rafael H. de Souza Siragusi,&nbsp;Sheila C. Rahal,&nbsp;Jeana P. da Silva,&nbsp;Maria J. Mamprim,&nbsp;Eduardo B. Mayrink Cardoso,&nbsp;Anneke Moresco","doi":"10.1111/jmp.12740","DOIUrl":"10.1111/jmp.12740","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Radiographs are useful for the initial evaluation of the hip joints. The information can be utilized for the betterment of animal health or other goals such as anatomic studies and gait analysis, among others. Therefore, this study aimed to evaluate radiographic measurements of the hip joint in capuchin monkeys, kept under human care at a reference center for wildlife.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twelve capuchin monkeys (<i>Sapajus</i> spp.) (three adult males, seven adult females, and two sub-adult females) were evaluated. Ventrodorsal radiographic views were taken under chemical restraint. All measurements on the digital images were performed in triplicate by one examiner.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results and Conclusions</h3>\u0000 \u0000 <p>None of the measurements evaluated were statistically different between males and females. No statistical differences were found between hind limbs. The mean (±SD) Norberg angle was 104.92° (±2.82°) and the Wiberg angle was 15.26° (±1.86°). The percentage of the femoral head covered by the acetabulum was 68.57% (±3.65%) and the acetabular index depth to width ratio was 54.66% (±3.85%). In conclusion, the radiographic measurements showed certain morphological features of the hip joint in <i>Sapajus</i> spp. that contribute to improving species knowledge.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-Infection of Bertiella studeri and Mycobacterium tuberculosis in a Captive Rhesus Macaque (Macaca mulatta)","authors":"Fangui Min,&nbsp;Shuwu Huang,&nbsp;Ruike Wu,&nbsp;Lan Zhang,&nbsp;Jing Wang","doi":"10.1111/jmp.12735","DOIUrl":"10.1111/jmp.12735","url":null,"abstract":"<div>\u0000 \u0000 <p><i>Bertiella studeri</i>, a typical intestinal cestode of nonhuman primates, accidentally infects human beings. However, <i>B</i>. <i>studeri</i> infection in monkeys has been rarely reported in recent years. A case of <i>B</i>. <i>studeri</i> infection was identified in one captive rhesus macaque with natural infection of <i>Mycobacterium tuberculosis</i>. This study contributes to alerting the public of this helmintic zoonosis, though its infection rate is quite lower in recent years.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Kidney Disease and Kidney Stone in a Wild Chimpanzee (Pan troglodytes verus) in Côte d'Ivoire","authors":"Jenny E. Jaffe,&nbsp;Kerstin Mätz-Rensing,&nbsp;Markus Ulrich,&nbsp;Tobias Gräßle,&nbsp;Verena Behringer,&nbsp;Roman M. Wittig,&nbsp;Fabian H. Leendertz","doi":"10.1111/jmp.12739","DOIUrl":"https://doi.org/10.1111/jmp.12739","url":null,"abstract":"<p>An older wild female chimpanzee (<i>Pan troglodytes</i>) was found dead with a large calcium oxalate stone in the renal pelvis. Histopathological changes included glomerulosclerosis, interstitial nephritis and fibrosis, focal mineralization, and medial hypertrophy. Urinary albumin-creatinine-ratio showed increased values from 15 months before death. Causes of the kidney disease remain unconfirmed.</p>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12739","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142324693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Gut Microbiota of Pig-Tailed Macaque (Macaca nemestrina) in Selected Habitats in Malaysia","authors":"Nur Azimah Osman,&nbsp;Millawati Gani,&nbsp;Roberta Chaya Tawie Tingga,&nbsp;Muhammad Abu Bakar Abdul-Latiff,&nbsp;Abd Rahman Mohd-Ridwan,&nbsp;Eddie Chan,&nbsp;Badrul Munir Md-Zain","doi":"10.1111/jmp.12737","DOIUrl":"https://doi.org/10.1111/jmp.12737","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The gut microbiota plays an important role in primates, which may be associated with their habitat. In Malaysia, pig-tailed macaques (<i>Macaca nemestrina</i>) live in different habitat environments and have traditionally been used for coconut plucking for more than a century. There is currently no information regarding the gut microbiota of this macaque in Malaysia. To address this oversight, this study employed a fecal metabarcoding approach to determine the gut microbiota composition of pig-tailed macaques and establish how these microbial communities correspond with the macaque external environments of residential area, forest edge, and fragmented forest.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>To determine this connection, 300 paired-end sequences of 16S rRNA were amplified and sequenced using the MiSeq platform.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the pig-tailed macaque fecal samples, we identified 17 phyla, 40 orders, 52 families, 101 genera, and 139 species of bacteria. The most prevalent bacterial families in the gut of pig-tailed macaques were Firmicutes (6.31%) and Proteobacteria (0.69%). Our analysis did not identify a significant difference between the type of environmental habitat and the gut microbiota composition of these macaques.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>There was great variation in the population richness and bacterial community structure. The abundance of Firmicutes and Proteobacteria helps this macaque digest food more easily while maintaining a healthy gut microbiota diversity. Exploring the gut microbiota provides an initial effort to support pig-tailed macaque conservation in the future.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142320708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of the Serum Microbiota and Circulating Metabolites in Cynomolgus Monkeys With Spontaneous Type 2 Diabetes Mellitus","authors":"Chaoyang Tian,&nbsp;Qunhui Yang,&nbsp;Haizhou Lv,&nbsp;Feng Yue","doi":"10.1111/jmp.12738","DOIUrl":"https://doi.org/10.1111/jmp.12738","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Type 2 diabetes mellitus (T2DM) is widely recognized as a serious global public health concern with a substantial economic burden on patients, their families, and society. Accumulating evidence suggests that an etiologic role for serum microbiota and circulating metabolites in the pathogenesis of T2DM. This study aims to characterize the serum microbiota and circulating metabolites in cynomolgus monkeys with spontaneous T2DM, and provide a reference for the diagnosis and treatment of clinical T2DM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We collected serum samples of the 14 cynomolgus monkeys (15–20 years old, male) for serum microbiota analysis by 16S rRNA gene V3-V4 region amplicon sequencing and circulating metabolites analysis by ultra-high-performance liquid chromatography–tandem mass spectrometry, of which seven were spontaneous T2DM cynomolgus monkeys and seven were healthy controls.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our results showed that the serum microbiota abundance and diversity were significantly increased in cynomolgus monkeys with spontaneous T2DM compared to healthy controls, the phyla of <i>Cyanobacteria</i> and <i>Chloroflexi</i> and the genera of <i>Lactobacillus, rhodobacter</i> and <i>collinsella</i> were also significantly increased. A total of 114 serum differentially expressed metabolites (DEMs) were identified, of which 22 were selected as potential biomarkers candidates related to spontaneous T2DM in cynomolgus monkeys by multivariate data analysis. In addition, serum levels of total SCFAs, acetate, butyrate, caproate, isobutyrate, and isovalerate were also significantly increased in the present study. The correlation network analyses have selected certain key DEMs, such as D-Psicose, 4-Oxoproline, D-Glutamine, and Hydroxyphenyllactic acid, which may serve as potential biomarkers for distinguishing between T2DM and healthy controls.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our results provide preliminary insights on perturbed serum microbiota and circulating metabolites of cynomolgus monkeys with spontaneous T2DM. These findings would be useful to develop microbiota-based strategies for T2DM prevention and control.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142276648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Experimental Study to Optimize Neuromuscular Blockade Protocols in Cynomolgus Macaques: Monitoring, Doses, and Antagonism","authors":"Hélène Letscher,&nbsp;Julien Lemaitre,&nbsp;Emma Burban,&nbsp;Roger Le Grand,&nbsp;Pierre Bruhns,&nbsp;Francis Relouzat,&nbsp;Aurélie Gouel-Chéron","doi":"10.1111/jmp.12736","DOIUrl":"https://doi.org/10.1111/jmp.12736","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Neuromuscular blocking agents (NMBAs) are a crucial component of anesthesia and intensive care through the relaxation of skeletal muscles. They can lead to adverse reactions such as postoperative residual neuromuscular block. Only one agent is capable of an instant block reversal in deep block situations, but is restricted to aminosteroid agents. Among animal models, non-human primates are an essential model for a great diversity of human disease models. The main objective of this study was to establish a model for NMBA monitoring with current available drugs before testing new reversal agents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Seven healthy male cynomolgus macaques were randomly assigned to this study. Experiments using macaques were approved by the local ethical committee (CEtEA #44). All animals were anesthetized according to institutional guidelines, with ketamine and medetomidine, allowing IV line placement and tracheal intubation. Anesthesia was maintained with isoflurane. Either rocuronium bromine (with or without sugammadex reversal) or atracurium besylate was evaluated. Monitoring was performed with two devices, TOF-Watch and ToFscan, measuring the T4/T1 and the T4/Tref ratios, respectively. Nonparametric Mann–Whitney statistical analyses were done when indicated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>NMBA monitoring required adaptation compared to humans, such as stimulus intensity and electrode placement, to be efficient and valid in cynomolgus macaques. When administered, both NMBAs induced deep and persistent neuro-muscular block at equivalent doses to clinical doses in humans. The rocuronium-induced profound neuromuscular block could be reversed using the cyclodextrin sugammadex as a reversal agent. We report no adverse effects in these models by clinical observation, blood chemistry, or complete blood count.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These results support the use of non-human primate models for neuromuscular block monitoring. This represented the first step before the forthcoming testing of new NMBA-reversal agents.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12736","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142276649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse Large B-Cell Lymphoma in a Cynomolgus Monkey","authors":"Heling Li,&nbsp;Long Zhang,&nbsp;Zhigang Chen,&nbsp;Faliang Zong,&nbsp;Baohong Tian,&nbsp;Xinglong Chen,&nbsp;Deli Liu,&nbsp;Qing Ning,&nbsp;Hong Wang","doi":"10.1111/jmp.12734","DOIUrl":"10.1111/jmp.12734","url":null,"abstract":"<div>\u0000 \u0000 <p>A captive 17-year-old male cynomolgus monkey (<i>Macaca fascicularis</i>) developed diffuse large B-cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Treatment of Cryptococcus gattii in an Immunocompetent Adult Rhesus Macaque (Macaca mulatta)","authors":"Joshua M. Taylor,&nbsp;Cassandra O. Cullin,&nbsp;Andrew J. Haertel,&nbsp;Anne D. Lewis,&nbsp;Lauren Renner","doi":"10.1111/jmp.12733","DOIUrl":"10.1111/jmp.12733","url":null,"abstract":"<div>\u0000 \u0000 <p>An adult female rhesus macaque presented during routine annual physical examination for evaluation of a 2.5-cm diameter superficial ulcerated dermal lesion that was subsequently diagnosed as a systemic fungal infection caused by <i>Cryptococcus gattii</i>. <i>Cryptococcus gattii</i> is one of several basidiomycetic yeasts responsible for pulmonary, neurologic, and disseminated infections in humans and animals. This report describes the diagnosis, management, and clinical resolution of a <i>C. gattii</i> infection in an immunocompetent 5-year-old female rhesus macaque.</p>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staphylococcus spp. as part of the microbiota and as opportunistic pathogen in free-ranging black-tuffed marmosets (Callithrix penicillata) from urban areas: Epidemiology, antimicrobial resistance, and pathology","authors":"Daniel Oliveira dos Santos,&nbsp;Bruna Hermine de Campos,&nbsp;Thayanne Gabryelle Viana de Souza,&nbsp;Yasmin Gonçalves de Castro,&nbsp;Geraldo Alves Neto,&nbsp;André Duarte Vieira,&nbsp;Letícia Neves Ribeiro,&nbsp;Caio Castro Cunha de Figueiredo,&nbsp;Janaina Ribeiro Duarte,&nbsp;Vinícius Henrique Barbosa Amaral,&nbsp;Lucas Reis de dos Souza,&nbsp;Nayara Ferreira de Paula,&nbsp;Carlyle Mendes Coelho,&nbsp;Herlandes Penha Tinoco,&nbsp;Ayisa Rodrigues Oliveira,&nbsp;Marcelo Pires Nogueira de Carvalho,&nbsp;Rodrigo Otávio Silveira Silva,&nbsp;Renato Lima Santos","doi":"10.1111/jmp.12732","DOIUrl":"10.1111/jmp.12732","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Marmosets (<i>Callithrix</i> sp.), including black-tuffed marmosets (<i>C. penicillata</i>), are neotropical primates that can be highly adapted to urban environments, especially parks and forested areas near cities. <i>Staphylococcus</i> spp. are part of the microbiota of many different hosts and lead to opportunistic severe infection. Isolates from wild animals can be resistant to antimicrobial drugs. However, there are a few studies that evaluated <i>Staphylococcus</i> spp. in neotropical primates. The goal of this study was to evaluate <i>Staphylococcus</i> spp. isolated from free-ranging black-tuffed marmosets.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Marmosets were captured in six urban parks. After sedation, skin and rectal swabs and feces were sampled. <i>Staphylococcus</i> spp. isolates were identified by MALDI-ToF and their antimicrobial susceptibility was determined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Over 30% of captured individuals were positive for <i>Staphylococcus</i> spp., and <i>S. aureus</i> was the most isolated species followed by <i>Mammaliicoccus</i> (<i>Staphylococcus</i>) <i>sciuri</i>. With the exception of the marmoset subjected to necropsy, none of the other had lesions, which supports that notion that <i>Staphylococcus</i> spp. are members of the microbiota, but also opportunistic pathogens. Most isolates were susceptible to all antimicrobials tested; however, one isolate of <i>S. epidermidis</i> was resistant to multiple antimicrobials (penicillin, cefoxitin, ciprofloxacin, clindamycin, and erythromycin). We considered <i>S. aureus</i> as the main staphylococci to colonize black-tuffed marmosets.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Black-tuffed marmosets can be colonized by several <i>Staphylococcus</i> species, most frequently by <i>S. aureus</i>, and the majority of isolates were sensible to the antimicrobials tested. One <i>S. epidermidis</i> isolate was considered multidrug resistant.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 5","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}